Clinical trials: sponsored by Taichung Veterans General Hospital
Knee Osteoarthritis
Therapeutic Effect of Oral Hyaluronic Acid on Knee Osteoarthritis
The goal of this clinical trial is to investigate the effect of oral hyaluronate in patients with knee osteoarthritis. The main question it aims to answer is: the therapeutic effect in the combined treatment of oral nutritional…
- Trial name
- NCT07033312
- Testing
- oral hyaluronate and injection, hyaluronate injection
- Where
- Taiwan
- Volunteers
- 44 people
- Sponsor
- Taichung Veterans General Hospital
Safety Issues, Chronic Hepatitis B
Tenofovir Alafenamide Switching Therapy in Kidney or Liver Transplant Recipients With Chronic HBV Infection
tenofovir alafenamide (TAF) has been approved to be highly effective and safe in patients with chronic hepatitis B (CHB), therefore TAF may be a good option in kidney or liver transplant patients with chronic HBV infection.
- Conditions
- Safety Issues, Chronic Hepatitis B, Transplant Recipient
- Trial name
- NCT05410496
- Testing
- Tenofovir Alafenamide 25 MG
- Where
- 2 sites in Taiwan
- Volunteers
- 52 people
- Sponsor
- Taichung Veterans General Hospital
Thyroid Cancer
Follow up for Patients With Thyroid Cancer Planed for Radioiodine Scan or Treatment
The prevalence of thyroid cancer has increased in recent decades. Patients with thyroid cancer need to choose between Thyrogen® injection and Eltroxin® withdrawal before radioiodine therapy or scan.
- Trial name
- NCT03624751
- Testing
- radioiodine
- Where
- Taiwan
- Volunteers
- 107 people
- Sponsor
- Taichung Veterans General Hospital
Acute Ischemic Stroke From Large Vessel Occlusion
SGLT2 Inhibitor Utilization Re-perfusion Therapy
Background: Reperfusion therapies, including intravenous rt-PA and mechanical thrombectomy, significantly improve outcomes in acute ischemic stroke.
- Trial name
- SUPER (NCT06858436)
- Testing
- Canagliflozin 100mg
- Volunteers
- 150 people
- Sponsor
- Taichung Veterans General Hospital
Head and Neck
4DryField PH and Head and Neck Operations.
The aim of this study is to investigate whether 4DryField can reduce postoperative blood loss and drain duration following head and neck surgery.
- Trial name
- NCT07487636
- Testing
- Polysaccharide based hemostat (4DryField PH)
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Taichung Veterans General Hospital
Oncology, Radiology
Upfront Neck Dissection Before Radiotherapy in Stage N3 Nasopharyngeal Carcinoma: A Retrospective Study
This retrospective observational study aims to evaluate the association between neck tumor burden and high-risk imaging features with locoregional recurrence and distant metastasis in patients with stage N3 nasopharyngeal…
- Trial name
- NCT07180173
- Testing
- Salvage Neck Treatment
- Where
- Taiwan
- Volunteers
- 7 people
- Sponsor
- Taichung Veterans General Hospital
Ischemic Stroke, Embolic Stroke of Undetermined Source
SENIOR: Stroke Prevention in the Elderly by Patent Foramen Ovale closuRe vs Anticoagulation
Patent foramen ovale (PFO) is an important mechanism of embolic stroke of undetermined source (ESUS). Current guidelines recommend PFO closure for high-risk PFO in patients younger than 60 years, and a recent retrospective cohort…
- Conditions
- Ischemic Stroke, Embolic Stroke of Undetermined Source, Patent Foramen Ovale (PFO), Elderly
- Trial name
- SENIOR (NCT07479147)
- Testing
- PFO closure, Medication
- Where
- 3 sites in Taiwan
- Volunteers
- 400 people
- Sponsor
- Taichung Veterans General Hospital
Breast Cancer Females
Dextrose Hydrodissection for Post-Breast Cancer Chest Wall and Axillary Tightness.
The goal of this clinical trial (prospective case series) is to evaluate the feasibility, safety, and preliminary clinical outcomes of ultrasound-guided dextrose prolotherapy in female breast cancer survivors with persistent…
- Trial name
- NCT07378319
- Testing
- ultrasound guided dextrose prolotherapy
- Where
- Taiwan
- Volunteers
- 15 people
- Sponsor
- Taichung Veterans General Hospital
Analgesia
ESP Versus PIFB for Analgesia in Open Cardiac Surgery: a Randomized Control Trial
This clinical trial compares analgesia efficiency and recovery outcomes between two different fascial plane block techniques (ESPB vs.PIFB) in cardiac surgery patients participant population/health conditions].
- Trial name
- NCT06322810
- Testing
- Erector spinae plane block (ESPB), Pecto-intercostal fascial plane blok (PIFB)
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Taichung Veterans General Hospital
Colorectal Cancer
Clinical Outcomes of Treatment With Immunomodulator Plus Cancer Therapies for Patients With Colorectal Cancer
This study aims to evaluate the survival and treatment outcomes among colorectal cancer patients undergoing anti-cancer treatment, both with and without an immunomodulator.
- Trial name
- NCT06557668
- Where
- 2 sites in Taiwan
- Volunteers
- 250 people
- Sponsor
- Taichung Veterans General Hospital
Chronic Rhinosinusitis, Postoperative Care
Effect of Chinese Herbal Medicine Nasal Irrigation on the Postoperative Care of Chronic Rhinosinusitis
Investigators tried to evaluate the efficacy and safety of Chinese herbal medicine nasal irrigation as an adjuvant therapy after FESS.
- Trial name
- Breeze Clear (NCT07340411)
- Testing
- Chinese herbal medicine Powder, Salt Powder
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Taichung Veterans General Hospital
Stroke, Hemiparesis After Stroke
The Impact of Neuronavigation in rTMS for Hemiplegic Stroke Patients.
This is a randomized, controlled trial investigating the efficacy and precision of neuronavigation -guided repetitive transcranial magnetic stimulation (rTMS) for motor recovery in patients with subacute stroke hemiparesis.
- Trial name
- NeurorTMS-HS (NCT07284017)
- Testing
- Neuronavigation-Assisted rTMS for Stroke Hemiparesis, Standard Localization rTMS for Stroke Hemiparesis
- Volunteers
- 30 people
- Sponsor
- Taichung Veterans General Hospital
Non-Small Cell Lung Cancer (MeSH Term: Carcinoma, Non-Small-Cell Lung), Drug-Related Side Effects and Adverse Reactions (MeSH Term)
Cancer Therapy-Related Cardiac Dysfunction Associated With EGFR-TKIs in Advanced EGFR-mutant Non-small Cell Lung Cancer
This study investigated the incidence of cardiac dysfunction in patients with advanced or recurrent epidermal growth factor receptor (EGFR)-mutant non-small cell lung cancer treated with EGFR- tyrosine kinase inhibitors.
- Conditions
- Non-Small Cell Lung Cancer (MeSH Term: Carcinoma, Non-Small-Cell Lung), Drug-Related Side Effects and Adverse Reactions (MeSH Term), Egfr Tyrosine Kinase Inhibitor, Cardiotoxicity
- Trial name
- NCT07267247
- Testing
- EGFR-TKI, EGFR tyrosine kinase inhibitor
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Taichung Veterans General Hospital
Chronic Migraine
Laser Acupuncture for Chronic Migraine
A single-blind randomized controlled trial was conducted from October 2024 to May 2025. Chronic migraine patients were randomly assigned in a 1:1 ratio to receive either Laser acupuncture or sham treatment.
- Trial name
- LAFCM (NCT06219694)
- Testing
- Laser Acupuncture
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Taichung Veterans General Hospital
General Surgery, Oncology
3D Modeling for Detecting Locally Advanced Rectal Cancer With Positive Circumferential Resection Margin
This retrospective study aims to develop an AI-assisted 3D modeling system to improve staging accuracy for stage II-III locally advanced rectal cancer (LARC).
- Conditions
- General Surgery, Oncology, Medical Informatics
- Trial name
- NCT07183124
- Testing
- AI-Assisted 3D Imaging Model for Tumor and CRM Assessmen
- Where
- Taiwan
- Volunteers
- 1,500 people
- Sponsor
- Taichung Veterans General Hospital
Traumatic Anosmia
The Effect of Oral Theophylline on Traumatic Anosmia
This study aimed to improve the treatment outcomes of patients with post-traumatic anosmia through medication and olfactory training.
- Trial name
- theophylline (NCT07171021)
- Testing
- Theophylline 200 mg, olfactory training
- Where
- Taiwan
- Volunteers
- 158 people
- Sponsor
- Taichung Veterans General Hospital
Diabetes
Point-of-Care Testing in Outpatient Diabetes Care
Using a point-of-care (POC) platform, the investigators will investigate the effects of POC testing for glycated hemoglobin (HbA1c) and cystatin C at out-patient clinics on long-term diabetes outcomes.
- Trial name
- NCT06684990
- Testing
- POC testing
- Where
- Taiwan
- Volunteers
- 222 people
- Sponsor
- Taichung Veterans General Hospital
Breast Cancer
Factors Affecting Rehabilitation Time for Postoperative Complications Among Breast Cancer Patients
Breast cancer patients who had undergone surgery, chemotherapy and radiotherapy suffered from complications, including shoulder stiffness, lymphedema and scar contracture. These symptoms impaired one's ADL function.
- Trial name
- NCT05401877
- Testing
- therapies for breast cancer
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- Taichung Veterans General Hospital
Coronary Bypass Graft Stenosis, Valvular Heart Disease
Comparison of Post-operation Cardiopulmonary Capacity of Patients Underwent Conventional and Robot-assisted Coronary Artery Bypass Graft and Valve Replacement Surgery
Robotic surgery is one of the most popular minimally invasive procedures for patients with coronary artery disease or valvular diseases.
- Trial name
- NCT05430568
- Testing
- robot-assisted surgery
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Taichung Veterans General Hospital
Axillary Web Syndrome, Breast Cancer
Clinical Outcome of Extracorporeal Shock Wave Therapy in Patient With Axillary Web Syndrome
Axillary web syndrome(AWS) is common complication of breast cancer surgery. Overall, AWS affects more than a half of the patient receiving axillary lymph node dissection.
- Conditions
- Axillary Web Syndrome, Breast Cancer, Lymphedema, Extracorporeal Shock Wave Therapy
- Trial name
- NCT05082597
- Testing
- Low energy ESWT
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- Taichung Veterans General Hospital