Clinical trials: sponsored by Tanta University
Renal Insufficiency, Chronic
Efficacy and Safety of Metformin Versus Empagliflozin on Chronic Kidney Disease Progression
This randomized controlled trial aims at evaluating the efficacy and safety of the antidiabetics metformin versus empagliflozin on chronic kidney disease (CKD) progression in patients with CKD stages 2 or/and 3.
- Trial name
- NCT05373680
- Testing
- Metformin, Empagliflozin, Control
- Where
- 2 sites in Egypt
- Volunteers
- 118 people
- Sponsor
- Tanta University
Necrotic Immature Permanent Incisors
Effect of Different NanoScaffolds on Pulp Regeneration in Non-Vital Immature Permanent Teeth (Randomized Clinical Trial)
the clinical trial aims to evaluate efficency of different scaffolds in cases of regeneration
- Trial name
- Regeneration (NCT07121348)
- Testing
- Platelet rich fibrin
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Tanta University
Nephrotoxicity
L-Carnitine Protective Effect in Nephrotoxicity
The goal of this clinical trial is to assess the possible reno-protective effect of L-carnitine against cisplatin-induced nephrotoxicity in patients receiving cisplatin-based chemotherapy.
- Trial name
- LC (NCT07108777)
- Testing
- L-Carnitine Tartrate
- Where
- Egypt
- Volunteers
- 46 people
- Sponsor
- Tanta University
Anterior Disc Displacement
Ultrasound-Guided Botulinum Toxin A Injection for TMJ Disc Displacement With Reduction
This clinical trial was designed to evaluate the effectiveness of ultrasonography-guided botulinum toxin type A (BTX-A) injection into the lateral pterygoid muscle for the management of temporomandibular joint (TMJ) anterior disc…
- Trial name
- NCT07076355
- Testing
- Botulinum Toxin type a (Botox)
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Tanta University
Spinal Anesthesia, Percutaneous Nephrolithotomy
Comparative Study Between Spinal Anesthesia Versus General Anesthesia in Supine Percutaneous Nephrolithotomy Operation
The aim of this study is to evaluate the efficacy of spinal anesthesia as an alternative to general anesthesia in PCNL operation in supine position.
- Conditions
- Spinal Anesthesia, Percutaneous Nephrolithotomy, General Anesthesia
- Trial name
- NCT07114250
- Testing
- spinal anesthesia, General Anesthesia
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Tanta University
Spinal Anesthesia Administration, Analgesic
Study of The Analgesic Profile of Two Adjuvants Added to Low Dose Hyperbaric Bupivacaine Versus One Adjuvant in Patients Undergoing Anal Surgery Using Spinal Anesthesia
This study will be conducted to compare the efficacy of fentanyl and Dexmedetomidine as an additive to hyperbaric bupivacaine 0.5% in saddle block anesthesia on duration of analgesia in patients undergoing anorectal surgeries.
- Conditions
- Spinal Anesthesia Administration, Analgesic, Anorectal Surgery
- Trial name
- NCT07114263
- Testing
- Group F (fentanyl group), Group D :Dexmedetomidine group, Group DF :Fentanyl and Dexmedetomidine group
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Anesthesia, Opioid
The Effect of Opioid Free Anesthesia Using Ultrasound-Guided Bilateral Transversus Abdominus Plane Block and Dexmedetomidine Infusion
This study aimed to determine the effects of Opioid-free anesthesia using dexmedetomidine and bilateral Transversus abdominis plane block on the quality of recovery, incidence of Opioid-free anesthesia, and post-operative pain…
- Conditions
- Anesthesia, Opioid, Gynecological Surgery
- Trial name
- NCT07114237
- Testing
- Opioid Free Anesthesia, Control group (general anesthesia)
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Tanta University
Inflammatory Bowel Diseases
Pentoxifylline as Adjunctive Therapy in Patients With Ulcerative Colitis
The exact underlying mechanisms of ulcerative colitis (UC), an idiopathic, chronic inflammatory disease marked by diffused inflammation of the colon and rectum mucosa, are still unknown.
- Trial name
- NCT05558761
- Testing
- Pentoxifylline 400 MG
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Tanta University
Intraoperative Infusion, Lidocaine
Intraoperative Infusion of Either Lidocaine or Dexmedetomidine on Regional Cerebral Oxygen Saturation and Postoperative Delirium in Elderly Patients Undergoing Abdominal Surgeries
This study aims to compare the effect of intraoperative infusion of either lidocaine or dexmedetomidine on the incidence of postoperative delirium (POD) in elderly patients undergoing major surgeries.
- Conditions
- Intraoperative Infusion, Lidocaine, Dexmedetomidine, Cerebral Oxygen Saturation
- Trial name
- NCT07108764
- Testing
- Lidocaine, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Tanta University
Bovine Bone, Concentrated Growth Factor
Bovine Bone With or Without Concentrated Growth Factor in the Treatment of Chronic Periodontitis
The aim of this study is to compare bovine bone with or without concentrated growth factor in the treatment of chronic periodontitis.
- Conditions
- Bovine Bone, Concentrated Growth Factor, Chronic Periodontitis
- Trial name
- NCT07108790
- Testing
- Concentrated growth factors, collagen membrane and xenograft bone graft, Collagen membrane and xenograft bone graft
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Tanta University
Gastroesophageal Reflux Disease, Severity
Association Between Gastroesophageal Reflux Disease (GERD) Severity and Dental Caries
This study aimed to assess the relationship between gastroesophageal reflux disease (GERD) severity (based on upper gastrointestinal endoscopy) and dental caries severity.
- Conditions
- Gastroesophageal Reflux Disease, Severity, Dental Caries
- Trial name
- NCT07108751
- Testing
- Endoscopy
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Tanta University
Zygomaticomaxillary Complex Fracture, Orbital Floor Fractures
Evaluating The Prebent Titanium Mesh for Zygomatico-Orbital Reconstruction in Twelve Patients Measuring Multiple Ophthalmologic Parameters, Aesthetic Results, Orbital Volume, Area of Bone Defect, Layout Angle, Gab Length and The Accuracy of Reconstruction
Purpose: The aim of this study was to evaluate the role of using a prebent titanium mesh on a 3D-printed model as an intraoperative guide to reconstruct orbito-zygomatic-maxillary complex (OZMC) fractures.
- Conditions
- Zygomaticomaxillary Complex Fracture, Orbital Floor Fractures, Ophthalmic Trauma
- Trial name
- NCT07103187
- Testing
- Zygomatico-Orbital reconstruction
- Where
- Egypt
- Volunteers
- 12 people
- Sponsor
- Tanta University
Laparoscopic Percutaneous Extra-peritoneal Closure, Internal Ring
Laparoscopic Percutaneous Extra-peritoneal Closure of the Internal Ring With or Without Peritoneal Cauterization
This research project aims to evaluate pediatric patients who underwent laparoscopic Percutaneous Internal Ring Suturing (PIRS) for inguinal hernia.
- Conditions
- Laparoscopic Percutaneous Extra-peritoneal Closure, Internal Ring, Peritoneal Cauterization
- Trial name
- NCT07102277
- Testing
- Percutaneous Internal Ring Suturing (PIRS) with peritoneal cauterization, Percutaneous Internal Ring Suturing
- Where
- Egypt
- Volunteers
- 270 people
- Sponsor
- Tanta University
Ventilator Associated Pneumonia ( VAP), Mechanical Ventilation
Evaluation of the Role of Acetyl Cysteine in Ventilator Associated Pneumonia by Carbapenem Resistance Klebsiella
The aim of the study is to evaluate the role of addition of Acetyl cysteine in the management of VAP induced by carbapenem resistant klebsiella.
- Trial name
- NCT07097727
- Testing
- acetyl cysteine 600 mg, antibiotics and saline.
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Tanta University
Femoral Triangle Block, Adductor Canal Block
Femoral Triangle Block Versus Adductor Canal Block in Arthroscopic Anterior Cruciate Ligament Reconstruction
The aim of this study is to compare the postoperative analgesic effect of femoral triangle block (FTB) and adductor canal block (ACB)after arthroscopic anterior cruciate ligament (ACL) reconstruction.
- Conditions
- Femoral Triangle Block, Adductor Canal Block, Anterior Cruciate Ligament Reconstruction
- Trial name
- NCT06402110
- Testing
- Femoral Triangle Block, Adductor Canal Block
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Tanta University
Vitiligo
Microneedling Combined With Topical Crisaborole 2 % Ointment in Treatment of Vitiligo.
The goal of this clinical trial is to learn if topical crisaborole ointment works to treat vitiligo. It will also learn about the safety of the drug.
- Trial name
- NCT07088276
- Testing
- microneedling with topical crisaborole
- Volunteers
- 20 people
- Sponsor
- Tanta University
S100B, Neutrophils/Lymphocytes Ratio
Protein S100B Versus Neutrophils/Lymphocytes Ratio in Early Prediction of Brain Injury
The study aimed to evaluate the role of Protein S100B versus the neutrophil-to-lymphocyte ratio (NLR) as an early predictor biomarker and the value of amplitude-integrated electroencephalography (aEEG) as an early predictor and…
- Conditions
- S100B, Neutrophils/Lymphocytes Ratio, Prediction, Brain Injury
- Trial name
- NCT07093723
- Testing
- S100B Protein, Neutrophils to Lymphocytes ratio
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Interscalene Block, Suprascapular Nerve Block
Ultrasound Guided Interscalene, Suprascapular and Anterior Glenoid Nerve Blocks on Diaphragmatic Excursion and Analgesia Following Arthroscopic Shoulder Surgery
This study aims to evaluate the diaphragmatic movement and postoperative analgesia following anterior glenoid, suprascapular, and interscalene nerve blocks in patients undergoing elective arthroscopic shoulder surgery.
- Conditions
- Interscalene Block, Suprascapular Nerve Block, Anterior Glenoid Nerve Block, Diaphragmatic Excursion
- Trial name
- NCT07090733
- Testing
- Interscalene brachial plexus block, Suprascapular nerve block, Anterior glenoid block
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Tanta University
Melatonin, Left Ventricular Function
Melatonin Effects on the Left Ventricular Function in Neonates With Persistent Pulmonary Hypertension
This study aimed to evaluate the effect of melatonin on the left ventricular function in neonates with persistent pulmonary hypertension
- Conditions
- Melatonin, Left Ventricular Function, Neonates, Persistent Pulmonary Hypertension
- Trial name
- NCT07090720
- Testing
- Melatonin
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Tanta University
Joshi's Step, Buccal Mucosal Graft
Joshi's Step With Buccal Mucosal Graft Urethroplasty in Nearly Obliterated Bulbar Urethral Stricture
This study aims to evaluate the functional and surgical outcome of Joshi's step with buccal graft urethroplasty for the management of nearly obliterated bulbar urethral stricture.
- Conditions
- Joshi's Step, Buccal Mucosal Graft, Urethroplasty, Obliterated Bulbar Urethral Stricture
- Trial name
- NCT07088198
- Testing
- Joshi's step
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Tanta University