Clinical trials: sponsored by Tanta University
Norepinephrine, Sepsis
The Impact of Early Norepinephrine Administration on Outcomes of Patients With Sepsis-induced Hypotension
Septic shock is defined as sepsis with persistent hypotension requiring vasopressors to maintain mean arterial pressure (MAP)≥ 65 mmHg and a serum lactate level of > 2 mmol/L (18 mg/dL) despite sufficient volume resuscitation .
- Conditions
- Norepinephrine, Sepsis, Hypotension
- Trial name
- NCT05774054
- Testing
- Crystalloid, noradrenaline
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Tanta University
GINGIVAL RECESSION
Growth Factor Enhanced Matrix With Subepithelial Connective Tissue Graft or Collagen Membrane in Treatment of Gingival Recession
The study aimed to compare, the effectiveness of Growth Factor Enhanced Matrix (GEM 21s) ® combined either with free connective tissue graft or collagen membrane in the treatment of Miller class II gingival recession.
- Trial name
- NCT05782751
- Testing
- GROUPI, GROUP II
- Where
- 2 sites in Egypt
- Volunteers
- 10 people
- Sponsor
- Tanta University
Rheumatoid Arthritis
Evaluating the Effect of Digoxin and Ursodeoxycholic Acid in Patients With Rheumatoid Arthritis
The purpose of this study is to investigate the potential therapeutic effects of the cardiac glycoside digoxin and the secondary bile acid ursodeoxycholic acid (UDCA) on synovial inflammation and disease activity when…
- Trial name
- NCT04834557
- Testing
- Digoxin 0.25 mg, Ursodeoxycholic acid (UDCA) 500 mg
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University
Interscalene Block, Superficial Cervical Block
Interscalene Block Versus Pericapsular Nerve Block and Superficial Cervical Plexus Block for Arthroscopic Shoulder Surgery
Interscalene brachial plexus block (ISB) is considered the standard nerve block for shoulder surgery . It provides superior analgesia and reduced opioid-related adverse effects .
- Trial name
- NCT05768009
- Testing
- Interscalene brachial plexus block (ISB)
- Where
- Egypt
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Tanta University
Left Ventricular Diastolic Dysfunction, Weaning Failure
Left Ventricular Diastolic Dysfunction as a Predictor of Weaning Failure From Mechanical Ventilation
Both premature and delayed extubation prolong the duration of mechanical ventilation and the intensive care unit (ICU) length of stay and increase morbidity and mortality.
- Conditions
- Left Ventricular Diastolic Dysfunction, Weaning Failure, Mechanical Ventilation Complication, Diaphragmatic Disorder
- Trial name
- NCT04703387
- Testing
- transthoracic echocardiography
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Tanta University
Progesterone, Contraceptive Methods
Progesterone Containing Contraceptive Methods on Endogenous Progesterone Level
The aim of this study is to assess the effect of different progesterone containing contraceptive methods on safety and endogenous progesterone level
- Trial name
- NCT05742503
- Testing
- Depo-Provera, Implanon, Norgestrel
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Tanta University
Premature Ovarian Failure
Platelet Rich Plasma Injection Into Ovary of Patients With Premature Ovarian Insufficiency
All encountered cases with POI will be assessed and examined then investigated. Eligible cases will be included in the study
- Trial name
- NCT04149028
- Testing
- PRP injection inside the ovary by laparoscoy. The injection volume is 2 ml
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Tanta University
Pulp Response to Castor Oil
Evaluation of Pulp Response to Castor Oil
The present study was conducted to evaluate and compare pulp response to Castor oil versus Formocresol as Pulpotomy Medicaments in Primary Teeth
- Trial name
- NCT05723900
- Testing
- Castor oil, Formocresol
- Where
- Egypt
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Tanta University
Alveolar Recruitment Maneuvers, Atelectasis
Alveolar Recruitment Maneuvers on Reduction of Lung Atelectasis in Bariatric Surgery by Using Lung Ultrasound Score
The study aims to compare the staircase alveolar recruitment maneuver with PEEP titration versus sustained inflation alveolar recruitment maneuver by using lung ultrasound score as an indicator of improving lung atelectasis in…
- Conditions
- Alveolar Recruitment Maneuvers, Atelectasis, Bariatric Surgery
- Trial name
- NCT05720351
- Testing
- Lachmann maneuver, Staircase maneuver
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Tanta University
Anesthesia Refusal
A Comparative Evaluation of Nebulized Dexmedetomidine and Nebulized Ketamine as a Premedication in Pediatric Surgeries
preoperative anxiety and parental deprivation can be a traumatic time for young children undergoing surgery and remain challenges to anesthesiologists.
- Trial name
- NCT05719506
- Testing
- normal saline without drug, Dexmedetomidine, Ketamine
- Where
- 2 sites in Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tanta University
Postpartum Hemorrhage, Ligation
Uterine Artery Color Doppler Parameters After Bilateral Uterine Artery Ligation
The aim of this study is to assess Uterine artery color doppler parameters after bilateral uterine artery ligation (BUAL) for Postpartum Hemorrhage.
- Conditions
- Postpartum Hemorrhage, Ligation, Color Doppler, Uterine Artery
- Trial name
- NCT05584995
- Testing
- Control group, BUAL group
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Tanta University
Bilateral Uterine Artery Ligation, Intrapartum or Postpartum Hemorrhage
Bilateral Uterine Artery Ligation After Intrapartum or Postpartum Hemorrhage on Ovarian Reserve Markers and Pregnancy Outcome
The aim of this study is to assess the possible negative effects of uterine artery ligation on ovarian reserve markers and subsequent pregnancy outcomes
- Conditions
- Bilateral Uterine Artery Ligation, Intrapartum or Postpartum Hemorrhage, Ovarian Reserve Markers, Pregnancy Outcome
- Trial name
- NCT05647538
- Testing
- Bilateral uterine artery ligation
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Tanta University
Postoperative Pain
Pre-emptive Dexamethasone in Hip Arthroplasty
Certain studies suggested that preoperative administration of systemic glucocorticoids in patients undergoing hip or knee arthroplasty surgery may improve the postoperative analgesia owing to their anti-inflammatory effect.
- Trial name
- NCT04898920
- Testing
- Normal saline, Dexamethasone
- Where
- Egypt
- Volunteers
- 83 people
- Sponsor
- Tanta University
Hernia, Inguinal
The Analgesic Efficacy of Two Bupivacaine Concentrations for Combined Ilioinguinal and Iliohypogastric Nerve Block in Postherniorrhaphy Pain
The present study will be undertaken to compare the postoperative analgesic effect of 0.25% bupivacaine and 0.5% bupivacaine for unilateral ilioinguinal and Iliohypogastric nerve block after open inguinal hernia repair.
- Trial name
- NCT05687981
- Testing
- Bupivacaine, Dexamethasone
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Tanta University
Bronchopulmonary Dysplasia
Effect of Caffeine Versus Probiotic on Preterm Neonates With Bronchopulmonary Dysplasia
The aim of this study is to evaluate the effectiveness of caffeine versus probiotics supplementation as adjuvant therapy for preterm neonates with Bronchopulmonary dysplasia (BPD).
- Trial name
- NCT05682807
- Testing
- Caffeine, Probiotic Formula
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University
Serratus Anterior Plane Block, Thoracic Paravertebral Block
Ultrasound- Guided Continuous Serratus Anterior Plane Block Versus Ultrasound- Guided Continuous Thoracic Paravertebral Block in Multiple Traumatic Rib Fractures.
The aim of this study is to compare the analgesic efficacy of ultrasound guided continuous SAP block and ultrasound guided continuous TPVB in patients with multiple traumatic rib fractures.
- Conditions
- Serratus Anterior Plane Block, Thoracic Paravertebral Block, Ultrasound, Multiple Traumatic Rib Fractures
- Trial name
- NCT04710823
- Testing
- Thoracic paravertebral block, Serratus anterior plane block
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Tanta University
Diabetes MellitusType 1
Role of Alpha-lipoic Acid in Diabetes Melitus Type 1
This study aims at investigating the possible effect of alpha-lipoic acid on endothelial dysfunction and atherosclerosis in children with type 1 diabetes mellitus.
- Trial name
- NCT05679037
- Testing
- Alpha Lipoic Acid 600 MG Oral Capsule
- Volunteers
- 52 people
- Sponsor
- Tanta University
Persistent Helicobacter Pylori Infection
Effect of Probiotics on Eradication of Persistent H.Pylori Infection
This study aims to investigate the possible safety and efficacy of probiotics (Bifidobacterium Infants, Enterococcus Feacium, and Lactobacillus Acidophilus) on the eradication rate of Helicobacter pylori and the incidence of…
- Trial name
- NCT05674864
- Testing
- Bifidobacterium Infants plus Enterococcus Feacium plus Lactobacillus Acidophilus
- Where
- Egypt
- Volunteers
- 92 people
- Sponsor
- Tanta University
Non-bleeding Peptic Ulcer
Diosmin as Adjuvant Therapy in Treatment of Non-bleeding Peptic Ulcer
The aim of the study is to evaluate the safety and efficacy of diosmin as adjuvant therapy in treatment of non-bleeding peptic ulcer patients.
- Trial name
- NCT05670457
- Testing
- Diosmin
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Tanta University
Acne Vulgaris
Comparison Between Isotretinoin, Silymarin and Both in the Treatment of Acne Vulgaris
This study aims to compare the effects of isotretinoin and silymarin or both in treatment of acne and their effects on the level of IGF-1, SAA1 and malondialdehyde (MDA) in acne patients.
- Trial name
- NCT05666765
- Testing
- Isotretinoin ,silymarin
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Tanta University