Clinical trials: sponsored by Tanta University
Dexmedetomidine, Adenotonsillectomy
Intranasal Dexmedetomidine in Children Undergoing Adenotonsillectomy Suffering From Mild Upper Respiratory Tract Infection
The purpose of this study is to detect the efficacy of intranasal dexmedetomidine as a premedication to general anesthesia in pediatric patients with respiratory comorbidities undergoing adenotonsillectomy.
- Conditions
- Dexmedetomidine, Adenotonsillectomy, Respiratory Tract Infections
- Trial name
- NCT05639777
- Testing
- Dexmedetomidine group, control group
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Tanta University
Knee Osteoarthritis
Metformin as Adjuvant Therapy in Obese Knee Osteoarthritis Patients
This study aims to evaluate the possible efficacy and safety of addition of metformin to celecoxib in patients with knee osteoarthritis.
- Trial name
- NCT05638893
- Testing
- Metformin Hcl 500Mg Tab
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Tanta University
Trauma, Patient Satisfaction
Awake Endotracheal Intubation in Cervical Injury
The researcher will compare awake endotracheal intubation with glidescope video assisted laryngoscope vs fiberoptic bronchoscope in patients with traumatic cervical injury;
- Conditions
- Trauma, Patient Satisfaction, Airway Morbidity
- Trial name
- NCT05619965
- Testing
- sedative, Awake endotracheal intubation by Glidescope videolaryngoscope, Awake endotracheal intubation by Fiberoptic bronchoscope
- Volunteers
- 100 people
- Sponsor
- Tanta University
Moderate Persistent Asthma
The Possible Efficacy and Safety of L-carnitine and Biotin as Adjunctive Therapies in Children With Moderate Persistent Asthma
The Possible Efficacy and Safety of L-carnitine and Biotin as Adjunctive Therapies in Children with Moderate Persistent Asthma
- Trial name
- NCT05632549
- Testing
- L-Carnitine 500Mg Oral Tablet, Biotin Capsules
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Tanta University
Ultrasound-Guided, Transeversus Thoracic Plane Blocks
Combined PECS II and Transeversus Thoracic Plane Blocks Vs Serratus Anterior Plane Block in Modified Radical Mastectomy
The aim of this study is to evaluate the analgesic efficacy of combined ultrasound (US)-guided pectoral nerve (PECS) block II and transversus thoracic plane (TTP) block versus US-guided serratus anterior plane (SAP) block in…
- Conditions
- Ultrasound-Guided, Transeversus Thoracic Plane Blocks, Pectoral Nerve (PECS) Block, Serratus Anterior Plane Block
- Trial name
- NCT04908878
- Testing
- Pectoral nerve (PECS) block -transversus thoracic plane (TTP) block, Serratus anterior plane (SAP) block
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Tanta University
Postoperative Pain
Comparison of Ultrasound Guided Erector Spinae Plane Block and Ultrasound Guided Pericapsular Nerve Group Block for Pediatric Hip Surgery
Surgical repair of the hip can be extremely painful and is associated with considerable postoperative pain in children despite the use of systemic opioids.
- Trial name
- NCT04373577
- Testing
- erector spinae plane block, pericapsular nerve group block
- Where
- Egypt
- Volunteers
- 56 people
- Sponsor
- Tanta University
Analgesia
Comparison Between Ultrasound-guided Ilioinguinal, Iliohypogastric Nerve Blocks, TAP Block and Quadratus Lumborum Block in Patients Scheduled for Lower Segment Ceserian Sections.
To compare between Ultrasound guided ilioinguinal, iliohypogastric nerve blocks, TAP block and Quadratus lumborum block in patients scheduled for lower segment ceserian sections.
- Trial name
- NCT05617482
- Testing
- General anesthesia, Ilioinguinal, iliohypogastric nerve blocks, TAP block
- Volunteers
- 150 people
- Sponsor
- Tanta University
Breast Cancer
The Possible Efficacy and Safety of Lansoprazole Co-administration With Neoadjuvant Chemotherapy in Women With Breast Cancer
Investigation of the possible efficacy and safety of lansoprazole co-administration with neoadjuvant chemotherapy in tumor response in women with breast cancer who will be planned for surgery.
- Trial name
- NCT04874935
- Testing
- Lansoprazole
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Tanta University
Non Alcoholic Steatohepatitis
Comparative Clinical Study Between Empagliflozin Versus Pioglitazone in Non-diabetic Patients With Non-alcoholic Steatohepatitis
This study aims to evaluate the possible beneficial effect of empagliflozin versus pioglitazone on non-diabetic patients with non-alcoholic steatohepatitis (NASH). This study will be a randomized, comparative parallel study.
- Trial name
- NCT05605158
- Testing
- Pioglitazone 30mg, Empagliflozin 10 MG
- Where
- Egypt
- Volunteers
- 56 people
- Sponsor
- Tanta University
Breast Cancer Female
The Anti-tumor Effect of Metformin And Atorvastatin in Breast Cancer
This study aims at evaluating and comparing the anti-tumor effects of metformin and statins (hydroxyl-methyl-glutaryl-CoA reductase inhibitors) in patients with non-metastatic breast cancer (stage I, II, \& III).
- Trial name
- NCT05507398
- Volunteers
- 100 people
- Sponsor
- Tanta University
Breast Cancer, Peripheral Neuropathy
Role of Silymarin in Chemotherapy Toxicity and Cognition Improvement in Breast Cancer Patients
Aim of the work This study aims to evaluate the possible beneficial role of silymarin in attenuating both doxorubicin related cardiac and hepatic toxicities and paclitaxel associated peripheral neuropathy and improving cognitive…
- Conditions
- Breast Cancer, Peripheral Neuropathy, Cardiac Toxicities, Hepatic Toxicity
- Trial name
- NCT05595109
- Testing
- Silymarin
- Where
- Egypt
- Volunteers
- 56 people
- Sponsor
- Tanta University
Ovarian Carcinoma
Itraconazole in Advanced Ovarian Cancer
This is a randomized, placebo controlled; parallel study that will be conducted on 66 female patients with advanced epithelial ovarian carcinoma (stage III and stage IV) to compare effect of adding Itraconazole to paclitaxel and…
- Trial name
- NCT05591560
- Testing
- Itraconazole capsule
- Where
- Egypt
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Tanta University
Colo-rectal Cancer, Neuropathy;Peripheral
Protective Effect of Pentoxifylline Against Chemotherapy Induced Toxicities in Patients With Colorectal Cancer
This study aims to: Evaluate the possible protective effect of pentoxifylline against oxaliplatin induced peripheral neuropathy and chemotherapy induced mucositis in patients with stage II and stage III colorectal cancer.
- Conditions
- Colo-rectal Cancer, Neuropathy;Peripheral, Mucositis
- Trial name
- NCT05590117
- Testing
- Pentoxifylline, FOLFOX-6 regimen
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Tanta University
Diabetic Nephropathies
Niclosamide Role in Diabetic Nephropathy
This study is randomized, controlled, parallel, prospective clinical study will be conducted on 60 patients diagnosed with type 2 diabetes mellitus at least five years ago.
- Trial name
- NCT04317430
- Testing
- Niclosamide
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Injection Site Irritation
Valsalva Manoeuvre and Intravenous Dexmedetomidine on Attenuating Pain During Propofol Injection in Upper GIT Endoscopy
No previous study has cited the use of the Valsalva manoeuvre for the reduction of pain on propofol injection in comparison with dexmedetomidine injection.
- Trial name
- Valsalva (NCT05225610)
- Testing
- Valsalva Manoeuvre, Dexmedetomidine Injection [Precedex], normal Saline
- Where
- Saudi Arabia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Tanta University
Delayed Gastric Emptying
Evaluating Neostigmine Effect on Reducing Gastric Residual Volume as Compared With Metoclopramide and Ondansetron
One big problem in mechanically ventilated ICU patients is delayed gastric emptying. Delayed gastric emptying in these patients, causes intolerance and high gastric residual volume (GRV) that can lead to abdominal distention…
- Trial name
- NCT05342818
- Testing
- Neostigmine, Ondansetron 8mg, Metoclopramide Injection
- Where
- Saudi Arabia
- Volunteers
- 90 people
- Sponsor
- Tanta University
Efficacy of Erector Spinae Plane Block in Lower Limb Surgery in Pediatric
Erector Spinae Plane Block in Pediatric Lower Limb Surgery
Anesthesia will be induced in all patients using Fentanyl 1µg,propofol 2mg/kg and cisatracurium 0.15 mg/kg IV to facilitate endotracheal intubation, maintenance of anaesthesia afterward will be achieved by isoflurane1.5-2% in…
- Trial name
- NCT05369455
- Testing
- erector spinae plane block, ultrasound guided caudal block
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Tanta University
Beta Thalassemia With Increased Tricuspid Regurgitant Jet Velocity
Clinical Study to Evaluate the Possible Efficacy and Safety of L- Carnitine and Sildenafil in Children Having Beta Thalassemia With Increased Tricuspid Regurgitant Jet Velocity
This study aims to investigate the possible efficacy and safety of L_Carnitine and Sildenafil on patient with Beta thalassemia complicated with increased Tricuspid Regurgitant Jet Velocity
- Trial name
- NCT05584956
- Testing
- L_carnitine, Sildenafil
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Tanta University
Ulnar Neuropathy at Elbow
Efficacy of Ultrasound-Guided PRP Versus Corticosteroid Injection in Patients With Ulnar Neuropathy at Elbow
This study was be performed on 60 patients with ulnar neuropathy at elbow diagnosed clinically and by electrophysiology and/or ultrasonography selected from Physical medicine, Rheumatology \& Rehabilitation Department, Faculty of…
- Trial name
- NCT05567081
- Testing
- Triamcinolone Acetonide 40mg/mL, PRP
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tanta University
Pain, Postoperative, Hip Dysplasia
Ultrasound Guided Psoas Compartment Block vs Suprainguinal Fascia Iliaca Compartment Block
The aim of this study was to compare the intraoperative and the postoperative analgesic effect of psoas compartment block (PCB) and supra-inguinal fascia iliaca compartment block (SFIB) in pediatric patients undergoing…
- Trial name
- NCT05543109
- Testing
- Fentanyl, Propofol, Rocuronium
- Where
- Egypt
- Volunteers
- 85 people
- Sponsor
- Tanta University