Clinical trials: sponsored by Tanta University
Rheumatoid Arthritis
Pentoxifylline as Anti-Inflammatory in Patients With Rheumatoid Arthritis
Rheumatoid arthritis (RA) is a long-term inflammatory condition that leads to gradual damage of joints lined by synovial membranes, along with various potential effects outside of the joints.
- Trial name
- NCT06998628
- Testing
- Methotrexate, Pentoxifylline
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Tanta University
Rheumatoid Arthritis (RA
Dysphagia in Rheumatoid Arthritis
The primary goal of this cross-sectional study is to assess risk factors/predictors for dysphagia in RA. The secondary goals include demonstrating whether flexible fiberoptic pharyngolaryngoscopy can detect…
- Trial name
- NCT07401732
- Testing
- flexible fiberoptic pharyngolaryngoscopy
- Where
- 2 sites in Egypt
- Volunteers
- 30 people
- Sponsor
- Tanta University
Pediatric Dentistry, Post Pulpotomy Restoration
Use of Alkasite for Postpulpotomy Restoration
The aim of this study will be directed to: Evaluate the clinical performance of alkasite composite as a final restoration for pulpotomized primary molars.
- Trial name
- Cention-Forte (NCT07355920)
- Testing
- Cention Forte, Tetric® N-Ceram
- Where
- Egypt
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Tanta University
Pancreatic Cancer
Clinical Study Evaluating the Effect of Losartan
The pancreas is two organs packaged into one. The islets of Langerhans serve critical endocrine functions, and the exocrine portion is a major source of enzymes that are essential for digestion.
- Trial name
- NCT06539806
- Testing
- Losartan 50mg Tab
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University
Immediate Dental Implant
Modified Periosteal Inhibition With Simultaneous Implant Placement in Aesthetic Zone
A randomized controlled clinical and radiographic trial. Twenty sites with remaining roots or non-restorable teeth in the maxillary anterior region that fulfill the inclusion criteria will be selected from the Periodontology…
- Trial name
- NCT06519773
- Testing
- Modified periosteal inhibition
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Tanta University
Full Arch Implant Rehabilitation
Effect of Scanning Techniques on Accuracy of Mandibular Fixed Detachable Prostheses
This crossover clinical study aims to evaluate the influence of three different intraoral scanning techniques on the scanning accuracy and passive fit of mandibular implant-supported fixed detachable prostheses in completely…
- Trial name
- NCT07740265
- Testing
- Splinted Scan Body with composite, IO Connect Scanning Technique, Auxiliary Geometric Device Scanning Technique
- Where
- Egypt
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Tanta University
Extraction Socket Healing
Assessment of Topical Application of Chitosan 0.2% Chlorhexidine Gel on Wound Healing in Diabetic Patients
Despite efforts to prevent postoperative discomfort, immediate side effects of surgical extraction of lower molars include bleeding at the site of extraction, inflammation, pain, and alveolar osteitis especially in diabetic…
- Trial name
- NCT07429812
- Testing
- Surgical extraction of the offending tooth will be performed under local anesthesia using inferior alveolar nerve block technique with buccal mucosa infiltration, make an incision on the gingival tis
- Where
- Saudi Arabia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tanta University
Persistent Pulmonary Hypertension, Mechanical Ventilation Strategies
Pressure Regulated Volume Control Ventilation in Neonates Persistent Pulmonary Hypertension
This study aims to assess the clinical and respiratory outcomes of Pressure-Regulated Volume Control ventilation as compared with patient on pressure-controlled ventilation in neonates with persistent pulmonary hypertension.
- Conditions
- Persistent Pulmonary Hypertension, Mechanical Ventilation Strategies, Neonatal Intensive Care Unit (NICU), Ventilation
- Trial name
- NCT07850908
- Testing
- Pressure-Controlled Ventilation, Group II (Pressure-Regulated Volume Control)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Scapular Dyskinesis, Shockwave Therapy
Routine Rehabilitation Versus Shock Wave Therapy for Scapular Dyskinesis
It has been proposed that altered scapular muscle function can contribute to alterations in shoulder kinematics, which often lead to SD and are frequently associated with other shoulder pathologies.
- Trial name
- NCT07633340
- Testing
- Radial extracorporeal shock wave therapy (active comparator)
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Tanta University
Doxorubicin Induced Cardiotoxicity, Breast Cancer
Clinical Study to Evaluate The Cardioprotective Effect of Pentoxifylline Against Doxorubicin Induced Cardiotoxicity in Breast Cancer Patients
The goal of this clinical trial is to evaluate the cardioprotective effect of pentoxifylline against doxorubicin-induced cardiotoxicity in breast cancer patients. The main questions it aims to answer are: 1.
- Trial name
- PTX / BC (NCT07137793)
- Testing
- Pentoxifylline 400mg plus chemotherapy
- Where
- Egypt
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Tanta University
Hepatobiliary Disorders
Evaluation of Efficacy, Safety and Molecular Mechanism of Pentoxifylline Supplementation in Patients With Hepatic and Obstructive Jaundice
Investigating the efficacy, safety, and molecular mechanism of Pentoxifylline supplementation in improving elevated direct bilirubin level and liver function tests in patients with hepatic and post-hepatic jaundice
- Trial name
- NCT06944704
- Testing
- Pentoxifylline
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Tanta University
Glioma, Dapagliflozin (Forxiga)
Dapagliflozin Versus Dexamethasone Role in Pre-operative Management of Non- Diabetic Brain Tumor Patients
The aim of the study is to compare between the role of dapagliflozin versus dexamethasone in pre-operative management of non-diabetic glioma patients on levetiracetam as anti-seizure drug.
- Conditions
- Glioma, Dapagliflozin (Forxiga), Dexamethasone
- Trial name
- NCT06750458
- Testing
- DexamethasoneGroup III (n=25) (Dexamethasone group)
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Tanta University
Scapular Dyskinesis
Study of Early Scapular Dyskinesis
This study is a prospective blind study of periscapular muscle thickness measured with MSUS and correlate it with EMG findings.
- Trial name
- NCT07681999
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Tanta University
Edentulous Maxilla, Atrophic
Guided Pterygoid Implants: an Accuracy Study
The aim of this clinical study is to evaluate the accuracy of placing pterygoid implants using custom-made surgical guides in patients with atrophied posterior maxilla.
- Trial name
- G-PTERYGOID (NCT07840339)
- Testing
- 3D Printed Digital Surgical Guide
- Where
- Egypt
- Volunteers
- 9 people
- Sponsor
- Tanta University
Ulcerative Colitis, Ulcerative Colitis (UC)
Alpha Lipoic Acid in Ulcerative Colitis
This study aims at evaluating the efficacy and safety of alpha-lipoic acid as adjuvant therapy to mesalamine in patients with mild to moderate ulcerative colitis due to its effect as anti-oxidant and anti-inflammatory drug which…
- Trial name
- NCT06067698
- Testing
- "Mesalamine" and "alpha-lipoic acid"
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Probiotic, Ventilator Associated Pneumonia
Probiotic Role in Prevention of Ventilator Associated Pneumonia in Critically- Ill Children Admitted at Pediatric Intensive Care Unit
The aim of the work is to evaluate the impact of Probiotics supplementation on prevention of ventilator associated pneumonia in critically ill children admitted at Pediatric Intensive Care Unit at Tanta University Hospitals.
- Conditions
- Probiotic, Ventilator Associated Pneumonia, Critically- Ill Children
- Trial name
- NCT07848165
- Testing
- Probiotics, Standard management
- Where
- Egypt
- Volunteers
- 68 people
- Sponsor
- Tanta University
Cleft Palate
Repair of Oronasal Fistula Using Interpositional Buccal Pad of Fat as a Free Graft in a Cleft Palate Patient
36 cleft palate patients had residual oronasal fistula included in this study divided randomly to two groups group I (control group): the fistula was repaired using two layers (oral and nasal layers) group II (study group): The…
- Trial name
- NCT06807450
- Testing
- closure of oro-nasal fistula in cleft palate patients
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Tanta University
Modified Fixed Bridge
3D Printed vs CAD/CAM Rehabilitation of Primary Anterior Teeth Loss
compare 3D Printed versus CAD/CAM fabricated modified fixed appliance for rehabilitation of premature loss of anterior teeth in preschool children
- Trial name
- NCT07752147
- Testing
- 3D Printed modified fixed bridge, CAD/CAM fabricated modified fixed bridge
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Tanta University
Empgliflozin Cardioprotective Effect
Cardioprotective Effect of Empagliflozin in Breast Cancer Patients
Background: Doxorubicin (DOX) remains a cornerstone in adjuvant and neoadjuvant therapy for breast cancer, but its utility is hindered by dose-dependent cardiotoxicity.
- Trial name
- NCT07815808
- Testing
- Empagliflozin (EMPA), Metformin
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Tanta University
Ketamine, Cognitive
Intraoperative Ketamine Versus Lidocaine Infusion on Postoperative Cognitive Dysfunction in Patients Undergoing Hip Surgery
This study aims to compare effects of ketamine versus lidocaine on postoperative cognitive dysfunction in geriatric patient undergoing hip surgery.
- Conditions
- Ketamine, Cognitive, Dysfunction, Hip Surgeries
- Trial name
- NCT07838909
- Testing
- Group Ketamine, Group Lidocaine
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Tanta University