Clinical trials: sponsored by Tanta University
Amyloid, Fractional
Fractional CO₂ Laser for Primary Cutaneous Amyloidosis
This randomized, controlled clinical study will evaluate the clinical and ultrastructural effects, efficacy, and safety of fractional CO₂ laser in patients with primary cutaneous amyloidosis.
- Conditions
- Amyloid, Fractional, Laser
- Trial name
- FCO2-PCA (NCT07815132)
- Testing
- Fractional CO₂ Laser
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Tanta University
Pre-Eclampsia, Preeclampsia
Internal Jugular Vein Collapsibility Index for Volume Status Assessment in Preeclampsia in Correlation With Normotensive Parturients
This study aims to assess and analyze volume status in preeclamptic patients and compare these parameters with those of normotensive pregnant ones based on the change in internal jugular vein ultrasound-based indices.
- Trial name
- NCT07786246
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Tanta University
Poly Cystic Ovary Syndrome
Efficacy of Dapagliflozin Versus Metformin in Polycystic Ovary Syndrome
In PCOS (Polycystic Ovary Syndrome), studies have found impaired incretin secretion and activity, particularly in overweight/obese individuals.
- Trial name
- NCT07810998
- Testing
- Metformin, Dapagliflozin (10mg Tab)
- Volunteers
- 60 people
- Sponsor
- Tanta University
Neonatal Respiratory Distress, Lung Ultrasound Score
Predictive Value of Lung Ultrasound Combined With Serum ANGPL4 Levels for NICU Admission Needs in Late Preterm and Term Neonates With Respiratory Distress In The Transion Period
The aim of this study is to evaluate the validity of point-of-care lung ultrasound (POC-LUS) and serum ANGPL4 levels for predicting NICU admission needs in late preterm and full-term neonates with respiratory distress shortly…
- Trial name
- NCT07809971
- Testing
- Point of care lung ultrasound (POC-LUS), Serum ANGPTL4
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Tanta University
HELICOBACTER PYLORI INFECTIONS
Comparative Study Evaluating Safety and Effectiveness of ( Proton Pump Inhibitor Versus Vonoprazan ) Based Triple Therapy With or Without Zinc to Eradicate H. Pylori Infection
this Study Evaluating Safety and Effectiveness of (Proton Pump Inhibitor versus Vonoprazan) Based Triple Therapy with or without Zinc to Eradicate H. pylori Infection
- Trial name
- NCT07275827
- Testing
- zinc sulfate, Vonoprazan + amoxicillin + clarithromycin, proton pump inhibitor + amoxicillin
- Where
- Egypt
- Volunteers
- 88 people
- Sponsor
- Tanta University
HELICOBACTER PYLORI INFECTIONS, Helicobacter Infection
Vonoprazan vs Proton Pump Inhibitor With Vitamin D or Probiotics Based Triple Therapy for Eradication of Helicobacter Pylori Infection
Helicobacter pylori is a Gram-negative, spiral-shaped bacterium that infects up to 50% of the world's population, residing in the gastric mucosa and using the mucus layer for protection from the stomach's high acidity.
- Conditions
- HELICOBACTER PYLORI INFECTIONS, Helicobacter Infection, Helicobacter Pylori Gastrointestinal Tract Infection, Helicobacter Pylori Infected Patients
- Trial name
- NCT07293910
- Testing
- Vonoparazan, Vitamin D, Probiotic
- Where
- Egypt
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Tanta University
Diabetic Nephropathy Type 2
Vitamin D in Diabetic Neuropathy
Introduction Diabetic peripheral neuropathy (DPN) is among the most common chronic complications of diabetes mellitus and represents a major cause of morbidity, impaired quality of life, sleep disturbance, chronic pain, and…
- Trial name
- NCT07644520
- Testing
- Vitamin D
- Volunteers
- 150 people
- Sponsor
- Tanta University
Psoriatic Arthritis, Ultrasound Assessment
Apremilast and Adalimumab in Psoriatic Arthritis Patients
The aim of this work is to compare the efficacy of Apremilast combined with Methotrexate versus Adalimumab combined with Methotrexate
- Conditions
- Psoriatic Arthritis, Ultrasound Assessment, TNF
- Trial name
- NCT07398651
- Testing
- Adalimumab, Apremilast
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Thoracotomy Surgery, Analgesia
Ultrasound-guided Thoracic Mid-Point Transverse Process to Pleural Block Versus Thoracic Paravertebral Block for Post Thoracotomy Analgesia
The aim of the study is to compare the analgesic efficacy and safety of midpoint transverse process to pleura to pleural block versus Paravertebral block for post thoracic surgery analgesia.
- Conditions
- Thoracotomy Surgery, Analgesia, Thoracic Paravertebral Block
- Trial name
- NCT07799844
- Testing
- Group A (Thoracic Paravertebral Block ), Group B : thoracic Mid-Point Transverse Process to Pleural Block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Deep Iliacus Plane Block, Transmuscular Quadratus Lumborum Block
Deep Iliacus Plane Block Versus Transmuscular Quadratus Lumborum Block for Postoperative Analgesia After Total Hip Arthroplasty
This study aims to compare the analgesic efficacy, opioid consumption, motor function preservation, and quality of recovery of ultrasound-guided deep iliacus plane block (DIPB) and transmuscular quadratus lumborum block (QLB) in…
- Conditions
- Deep Iliacus Plane Block, Transmuscular Quadratus Lumborum Block, Postoperative Analgesia, Total Hip Arthroplasty
- Trial name
- NCT07798830
- Testing
- Deep iliacus plane block, Quadratus lumborum block
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Tanta University
The Effect of Preoperative Administration of Oral Tizanidine, Post Operative Pain
The Effect of Preoperative Administration of Oral Tizanidine on the Postoperative Pain and Sleep Quality
The majority of lower limb fractures treated with surgery often leading to significant morbidity and mortality. Despite improvements in perioperative care, about 20% suffer from severe postoperative complications.
- Trial name
- Tizanidine (NCT07800364)
- Testing
- Tizanidine
- Where
- Egypt
- Volunteers
- 68 people
- Sponsor
- Tanta University
Bipolar Radiofrequency Ablation, Unipolar Radiofrequency Ablation
Unipolar Versus Bipolar Radiofrequency Ablation in Knee Osteoarthritis Pain
This study aims to compare the efficacy of unipolar versus bipolar radiofrequency ablation (RFA) in knee osteoarthritis pain.
- Conditions
- Bipolar Radiofrequency Ablation, Unipolar Radiofrequency Ablation, Knee Osteoarthritis, Pain
- Trial name
- NCT07789340
- Testing
- Unipolar radiofrequency ablation, Bipolar radiofrequency ablation
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Tanta University
Bite Force, Stainless-steel Crown
Bite Force Recovery Following Pediatric Full Crown Restorations
A component of masticatory function is bite force. Dental caries is one factor that contributes to poor dental health, which has an overall negative influence on quality of life.
- Conditions
- Bite Force, Stainless-steel Crown, Masseter Muscle
- Trial name
- NCT07786805
- Testing
- Preformed BioFlx Crown, Preformed Stainless Steel Crown
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Tanta University
Unilateral Alveolar Cleft of Maxilla
Bone Marrow Aspirate Concentrate With Bovine Bone Graft for Unilateral Alveolar Cleft Reconstruction
This randomized clinical trial evaluated whether adding autologous bone marrow aspirate concentrate (BMAC) to a bovine-derived bone graft improves healing and bone regeneration in patients undergoing reconstruction of a…
- Trial name
- NCT07786259
- Testing
- BMAC-Enriched Bovine Bone Grafting, Bovine Bone Grafting
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Tanta University
Obstructive Sleep Apnea (OSA)
Fractional Exhaled Nitric Oxide as Possible Non - Invasive Biomarker to Assess Obstructive Sleep Apnea Severity
Aim of work 1. Primary aim: Asses correlation between FeNO level, OSA severity 2. Secondary aim: Clarifying FeNO's role as a biomarker to assess airway inflammation, Cut off value prediction to moderate and severe OSA and its…
- Trial name
- NCT07606898
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Tanta University
Pulpitis Reversible, Pulp Exposure, Dental
Comparative Evaluation of Eggshell Powder in Primary Teeth Pulpotomy
To assess \& compare clinical \& radiographic effects of Eggshell Powder, Biodentine and MTA as pulpotomy agents in primary teeth.
- Trial name
- NCT05812053
- Testing
- pulpotomy, cone beam computed tomography (CBCT) assessment
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Tanta University
Alveolar Bone Loss
VST vs Modified Periosteal Inhibition Technique
Losing a tooth in the upper front of the mouth is common, and many people choose a dental implant to replace it. When a tooth is removed, the thin layer of bone in front of the socket - the buccal, or front, bone - often shrinks…
- Trial name
- VST (NCT07784764)
- Testing
- VST, Mucoperiosteal inhibition
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Tanta University
HCV Infection ( Genotype 4) in CKD Patients
Treatment of CKD Patients With HCV
The goal of this clinical trial is to evaluate the optimal drug therapy of HCV in CKD Patients different stages with or without compensated cirrhosis.
- Trial name
- HCV/CKD (NCT07770984)
- Testing
- SOF+DCV, OBV/PTV/r) ± ribavirin (RBV)
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Tanta University
Intrathecal Morphine, Intrathecal Dexmedetomidine
Intrathecal Morphine Versus Intrathecal Dexmedetomidine Compared to Placebo for Postoperative Pain Relief After Spine Fixation Surgeries
This study aims to compare the efficacy of intrathecal morphine and intrathecal dexmedetomidine in reducing pain following lumbar spine fixation surgeries.
- Conditions
- Intrathecal Morphine, Intrathecal Dexmedetomidine, Placebo, Postoperative Pain
- Trial name
- NCT07777627
- Testing
- Intrathecal Morphine, Intrathecal Dexmedetomidine, Normal Saline
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University
Nasal Packing Duration, One-Day Packing
Comparative Study of Nasal Packing Duration: One-Day Packing Versus Three-Day Packing After Turbinate Surgery
This study aimed to assess the optimum timing for nasal packs removal after turbinate surgery by comparing removal after one day versus removal after three days.
- Conditions
- Nasal Packing Duration, One-Day Packing, Three-Day Packing, Turbinate Surgery
- Trial name
- NCT07775118
- Testing
- Nasal packing for 1 day, Nasal packing for 3 days
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Tanta University