Clinical trials: open to volunteers, sponsored by Tanta University
Lactium, Premedication
Lactium Premedication to Prevent Emergence Agitation
This biased coin sequential allocation, dose finding study will be conducted to determine the effective dose of oral lactium in 90% of children (ED90) for prevention of emergence agitation during recovery from adenotonsillectomy.
- Conditions
- Lactium, Premedication, Emergence Agitation, Adenotonsillectomy
- Trial name
- NCT07894484
- Testing
- Lactium
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Tanta University
Bipolar Radiofrequency Ablation, Unipolar Radiofrequency Ablation
Unipolar Versus Bipolar Radiofrequency Ablation in Knee Osteoarthritis Pain
This study aims to compare the efficacy of unipolar versus bipolar radiofrequency ablation (RFA) in knee osteoarthritis pain.
- Conditions
- Bipolar Radiofrequency Ablation, Unipolar Radiofrequency Ablation, Knee Osteoarthritis, Pain
- Trial name
- NCT07789340
- Testing
- Unipolar radiofrequency ablation, Bipolar radiofrequency ablation
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Tanta University
Benign Prostatic Hyperplasia With Outflow Obstruction
Learning Curve of Tri-lobar HoLEP Versus En-bloc HoLEP
Several HoLEP techniques have been developed, with the conventional tri-lobar and the en-bloc approaches being the most commonly practiced.
- Trial name
- NCT07890103
- Testing
- Tri-lobar HoLEP, En-bloc HoLEP
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Tanta University
SBP - Spontaneous Bacterial Peritonitis
N-Acetylcysteine in the Management of Spontaneous Bacterial Peritonitis
Spontaneous bacterial peritonitis (SBP) is one of the most serious infectious complications of liver cirrhosis and ascites. It affects approximately 10-30% of hospitalized patients with decompensated cirrhosis and carries an…
- Trial name
- NCT07803952
- Testing
- NAC
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
SBP - Spontaneous Bacterial Peritonitis
Nitazoxanide in Spontaneous Bacterial Peritonitis
Spontaneous bacterial peritonitis (SBP) is a life-threatening complication of liver cirrhosis characterized by infection of ascitic fluid in the absence of an evident intra-abdominal source.
- Trial name
- NCT07808450
- Testing
- Nitazoxanide (NTZ)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Irreversible Pulpitis
Effect of Temperature Elevation on the Antimicrobial Efficacy of Two Root Canal Irrigants in Primary Root Canal Infections: A Randomized Controlled Clinical Trial
evaluate the antimicrobial efficacy of preheated sodium hypochlorite and dexamethasone sodium phosphate and at room temperature in patients with primary root canal infection.
- Trial name
- NCT07906925
- Testing
- Dexamethasone Sodium Phosphate 10 MG/ML, Sodium Hypochlorite 2,5%
- Volunteers
- 40 people
- Sponsor
- Tanta University
Acne
A Split-Face Comparative Study of Mono Threads Versus Combination With Plasma Gel for the Treatment of Post-Acne Scars
This study aims to evaluate and compare the efficacy and safety of mono threads alone versus mono threads combined with plasma gel for the treatment of atrophic post-acne scars.
- Trial name
- NCT07903012
- Testing
- polydioxanone (PDO) mono threads, Mono Threads with Plasma Gel
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Tanta University
NAFLD (Nonalcoholic Fatty Liver Disease)
Evaluating the Safety and Efficacy of Roflumilast in the Treatment of Nonalcoholic Fatty Liver Disease Patients
Nonalcoholic fatty liver disease (NAFLD) is a global public health concern, and the leading cause of chronic liver disease, especially in developed countries.
- Trial name
- NCT07900087
- Testing
- Roflumilast
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
NAFLD (Nonalcoholic Fatty Liver Disease)
Evaluating the Safety and Efficacy of Rupatadine in the Treatment of Nonalcoholic Fatty Liver Disease Patients.
NAFLD is characterized by excessive hepatic fat accumulation without other recognized causes of increased fat content (e.g., alcohol, virus, drugs, and autoimmunity).
- Trial name
- NCT07900100
- Testing
- Rupatadin
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Rheumatoid Arthritis (RA
Efficacy and Safety of Dapagliflozin as an Adjunct to Conventional Disease-Modifying Antirheumatic Drugs in Patients With Rheumatoid Arthritis
Rheumatoid arthritis (RA) is a long-standing autoimmune inflammatory disease marked by continuous synovial inflammation, which contributes to progressive cartilage and bone damage, eventually resulting in joint destruction.
- Trial name
- NCT07901309
- Testing
- Dapagliflozin (10mg Tab)
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Tanta University
Post-Traumatic Atrophic Scar, Atrophic Scar
Nanofat Injection and Fractional CO2 Laser for Post-Traumatic Atrophic Scars
Post-traumatic atrophic scars are characterized by skin depressions caused by loss of collagen and can lead to cosmetic and psychological concerns.
- Conditions
- Post-Traumatic Atrophic Scar, Atrophic Scar, Scar
- Trial name
- NANOCO2-PTS (NCT07679217)
- Testing
- Autologous Nanofat Injection, Fractional CO2 Laser
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Anesthesia, Anxiety
Buzzy Bee for Pain and Anxiety Control During Pediatric Dental Local Anesthesia
The present study will evaluate the effectiveness of Buzzy Bee in reducing pain and physiological responses during maxillary buccal infiltration in children aged 5-7 years compared with a conventional injection protocol.
- Conditions
- Anesthesia, Anxiety, Pain, Children
- Trial name
- NCT07886333
- Testing
- Intervention A: Buzzy® Bee-Assisted Local Anesthesia, Intervention B: Conventional Local Anesthesia Technique
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Tanta University
Fluoride Varnishes, Molar Incisor Hypomineralisation
Nanohydroxyapatite Versus Sodium Fluoride Varnish in Remineralizing MIH Anterior Teeth
This randomized controlled clinical trial evaluates and compares the remineralization efficacy of a 8.6% nanohydroxyapatite (nano-HAp) varnish versus a standard 5% sodium fluoride (NaF) varnish in young permanent anterior teeth…
- Conditions
- Fluoride Varnishes, Molar Incisor Hypomineralisation, Permanent Anterior Teeth, Remineralization
- Trial name
- NCT07894510
- Testing
- Nanohydroxyapatite Varnish Application, Sodium Fluoride Varnish Application
- Where
- Egypt
- Volunteers
- 26 people
- Sponsor
- Tanta University
MTA, Pulp Caping
Clinical and Radiographic Evaluation of Dia-Root Bio MTA for Indirect Pulp Capping in Young Permanent Molars
This split-mouth randomized controlled clinical trial evaluates and compares the clinical and radiographic success of Dia-Root Bio MTA versus conventional Mineral Trioxide Aggregate (MTA Plus) as indirect pulp capping (IPC)…
- Conditions
- MTA, Pulp Caping, Permanent Molars, Radiographic Evaluation
- Trial name
- NCT07894523
- Testing
- Dia-Root Bio MTA Indirect Pulp Capping, MTA Plus Indirect Pulp Capping
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Tanta University
3D Printing, Oral Habit
3D-Printed Versus Conventional Palatal Cribs in Managing Tongue Thrusting Habit in Children
This randomized controlled clinical trial evaluates and compares the clinical effectiveness of 3D-printed palatal cribs versus conventional soldered palatal cribs in managing the tongue thrusting habit in pediatric patients.
- Conditions
- 3D Printing, Oral Habit, Patient Comfort
- Trial name
- NCT07895121
- Testing
- 3D-Printed Palatal Crib Appliance Therapy (Group I):, Conventional Soldered Palatal Crib Appliance Therapy (Group II)
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Tanta University
Clinical, Primary Teeth
Clinical Evaluation of Bioflx Crowns in Restoring Primary Anterior Teeth
This randomized controlled clinical trial evaluates and compares the clinical success and performance of prefabricated Bioflx crowns versus conventional Celluloid strip crowns in the restoration of badly decayed or traumatized…
- Conditions
- Clinical, Primary Teeth, Restoration, Crown
- Trial name
- NCT07883187
- Testing
- Bioflx Crown Restoration (Group I), Celluloid Strip Crown Restoration (Group II)
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Tanta University
Pulpectomy, Pulpitis - Irreversible
Clinical and Radiographic Evaluation of E-IodoCal in Primary Molar Pulpectomy
This randomized controlled split-mouth clinical trial evaluates the clinical and radiographic performance of E-IodoCal paste compared to zinc oxide-eugenol (ZOE) as root canal filling materials in primary molar pulpectomies.
- Conditions
- Pulpectomy, Pulpitis - Irreversible, Zinc Oxide, Root Canal Obturation
- Trial name
- NCT07883200
- Testing
- E-IodoCal Root Canal Obturation (Group I), Zinc Oxide-Eugenol Root Canal Obturation (Group II)
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Tanta University
Breast Cancer
Comparative Study Between (SGLT-2i) and (DPP-4i) in the Prevention of DIC
Background: Breast cancer is the most frequently diagnosed malignancy among women worldwide and a major cause of morbidity and mortality.
- Trial name
- SGLT2i/DPPi (NCT07436663)
- Testing
- Dapagliflozin (5-10 mg daily) - SGLT2 Inhibitor Therapy, Sitagliptin (DPP4 inhibitor), Standard Care (in control arm)
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Tanta University
Cardiotoxicity
Cardioprotection Effect of Linagliptin
1. Background and Rationale Breast cancer is one of the most common malignancies affecting women worldwide and represents a major health burden in Egypt.
- Trial name
- Linagliptin (NCT07852546)
- Testing
- Doxorubicin, Empaglifloz 5 mg orally once daily
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Tanta University
Hypotension After Spinal Anesthesia
Carotid Ultrasound for Post-Spinal Anesthesia Hypotension in Elderly Hip Surgery
This study aims to evaluate the predictability of preoperative carotid artery-corrected flow time (CFTc) for hypotension after spinal anesthesia in patients undergoing geriatric hip replacement surgery.
- Trial name
- NCT07876063
- Testing
- Ultrasound
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Tanta University