Clinical trials: sponsored by Technical University of Munich
Colonic Polyps
Computer Assisted Optical Assessment of Small Colorectal Polyps
The aim of the study is to develop a computer program which is able to distinguish between adenomatous and non- adenomatous polyps on the basis of optical features of the polyps.
- Trial name
- NCT02522702
- Testing
- Photography of polyps, resection of polyps
- Where
- Germany
- Volunteers
- 250 people
- Sponsor
- Technical University of Munich
Sleep Apnea Syndromes
Detection of Airway Obstruction by Manometry in Different Sleep Stages and Comparing it to DISE
Patients with OSA receive manometry measurements with Apneagraph (AG) during one night of sleep. All patients are simultaneously evaluated with polysomnography.
- Trial name
- NCT02969551
- Testing
- Manometry and possibly DISE
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Technical University of Munich
Pancreatitis, Acute, SIRS
Pancreatitis CytoSorbents (CytoSorb®) Inflammatory Cytokine Removal
Severe acute pancreatitis (SAP) has a mortality of up to 42%. The outcome of SAP is related to the development of SIRS and consecutive organ failures.
- Trial name
- PACIFIC (NCT03082469)
- Testing
- CytoSorb
- Volunteers
- 30 people
- Sponsor
- Technical University of Munich
Plantar Foot Pressure
Pedobarographic Changes After Forefoot Reconstruction
Static pedobarography is routinely used for pre- and postoperative questions regarding plantar foot pressure. This Investigation does insufficiently detect dynamic Forces.
- Trial name
- PEDfore (NCT02643485)
- Testing
- Forefoot surgery
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Survival , Tumor
Retrospective Evaluation of Liposarcoma
Retrospective Evaluation of Survival after Liposarcoma
- Trial name
- RELiSa (NCT03034252)
- Testing
- Patients with Liposarcoma
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Technical University of Munich
Abdominal Aortic Aneurysm, AAA
Screening Cardiovascular Patients for Aortic aNeurysms (SCAN)
The aim of the cohort study SCAN (Screening Cardiovascular patients for Aortic aNeurysms) is to establish a screening programm for patients with a high risk for an AAA.
- Trial name
- SCAN (NCT02179801)
- Where
- 2 sites in Germany
- Volunteers
- 1,000 people
- Sponsor
- Technical University of Munich
Colonic Polyp
Computer Assisted Measurement of Colorectal Polyps
Adenomas are polyps of the colorectum that have the potential to develop into colon cancer. However, some adenomas never become malignant tumors, or if so, progression from adenoma into cancer takes a long time.
- Trial name
- NCT02970760
- Where
- Germany
- Volunteers
- 500 people
- Sponsor
- Technical University of Munich
Adenoma
Endoscopic Full-thickness REsection of Residual Colorectal Lesions - The FiRE Study
Adenomatous lesions of the colon are premalignant lesions which have the potential to develop cancer. Therefore adenomas should be resected endoscopically (endo- mucosa resection, EMR).
- Trial name
- FiRE (NCT02353533)
- Testing
- over- the- scope full- thickness resection device (FTRD), EMR
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Technical University of Munich
Colon Adenoma, Diverticulosis
Impact of Diverticular Disease on the Detection of Colon Adenomas
Benign adenomas of the colon have the potential to degenerate and become malignant. Therefore adenomatous polyps should be detected and resected during colonoscopy.
- Trial name
- DECADE (NCT02057562)
- Where
- 2 sites in Germany
- Volunteers
- 1,000 people
- Sponsor
- Technical University of Munich
Fracture, Healed, Fibrous Union
Mid-term Outcome Following Revision Surgery of Clavicular Non- and Malunion
Background Treatment of clavicular non- and malunion is still challenging. Current surgical procedures often result in partially frustrating functional outcome along with high-grade subjective impairment and increased rates of…
- Trial name
- Nonunion (NCT02951468)
- Testing
- LCP plus iliac crest autograft
- Volunteers
- 14 people
- Sponsor
- Technical University of Munich
Knee Pain Treated With Knee Arthroplasty
Changes of Plantar Pressure After Knee Reconstructive Surgery
Knee reconstructive surgery (knee prosthesis, osteotomies) often results in changes of alignment of the lower limb axis. This affects also biomechanics of the hindfoot.
- Trial name
- PEDKnee (NCT02906735)
- Testing
- Surgery
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Infection of Total Knee Joint Prosthesis
Comparison of Two Different Techniques of Synovial Biopsy and Resistances of Cutaneous Smears in Suspected PPI
The purpose of this study is to determine whether an undirected synovial biopsy technique has the same accuracy in detecting periprosthetic joint infection in the knee as an arthroscopic assisted directed synovial biopsy…
- Trial name
- COSPI (NCT02594930)
- Testing
- synovial biopsy of total knee arthroplasty
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Technical University of Munich
Visualisation and Evaluation of Ampulla of Vater
Cap Assisted Upper Endoscopy to Visualize the Major Duodenal Papilla
Aim of the present study is the evaluation of the diagnostic value of a cap assisted upper GI-endoscopy compared to a standard upper GI-endoscopy regarding the visualisation and evaluation of the papilla duodeni major.
- Trial name
- Kappa-I (NCT02877797)
- Testing
- Cap
- Where
- Germany
- Volunteers
- 101 people
- Sponsor
- Technical University of Munich
Degenerative Cervical Spinal Stenosis, Cervical Disc Herniation
Multicentric Registry for the Detection of C5 Palsy After Anterior Cervical Discectomy and Fusion
Detect the reason for the frequently occurring C5 palsy after anterior cervical discectomy and fusion
- Conditions
- Degenerative Cervical Spinal Stenosis, Cervical Disc Herniation, Suspected Cervical Spine Instability
- Trial name
- C5registry (NCT02875431)
- Testing
- Patients undergo ACDF or cervical vertebral body replacement
- Where
- Germany
- Volunteers
- 1,087 people
- Sponsor
- Technical University of Munich
End Stage Renal Disease (ESRD)
Substitution of Acetate by Citrate in the Bicarbonate Based Hemodialysis
Acetate is the primary acidifying solution used in bicarbonate-based hemodialysis worldwide. It has been published in small trials or case series that the addition of acetate is associated with a rise in nitric oxide production…
- Trial name
- NCT02745340
- Testing
- Acetate by Citrate substitution and vice versa
- Where
- 2 sites in Germany
- Volunteers
- 100 people
- Sponsor
- Technical University of Munich
Observation of Neuromuscular Block, Respiratory Paralysis
Comparison of AMG and EMG to Avoid Residual Paralysis After General Anesthesia
This study evaluates three different neuromuscular monitoring devices (acceleromyography, one- or three-dimensional, and electromyography) with regard to their precision to detect residual paralysis after injection of…
- Conditions
- Observation of Neuromuscular Block, Respiratory Paralysis, Anaesthesia
- Trial name
- CAMEM (NCT02126852)
- Testing
- Acceleromyography (AMG, one-dimensionally), Acceleromyography (AMG, three-dimensionally), Electromyography (EMG)
- Where
- 2 sites in Germany
- Volunteers
- 214 people
- Sponsor
- Technical University of Munich
Sleep Apnea Syndrome
Upper Airway Collapse in Patients With Obstructive Sleep Apnea Syndrome by Drug Induced Sleep Endoscopy
This is a prospective, interventional cohort study of drug-induced sleep endoscopy (DISE). The goal is to evaluate the upper airway in a cohort of patients with obstructive sleep apnea hypopnea syndrome (OSAHS) diagnosed in a…
- Trial name
- NCT02588300
- Testing
- Drug induced sleep endoscopy
- Where
- Germany
- Volunteers
- 43 people
- Sponsor
- Technical University of Munich
Postoperative Complications
Haemodynamic Monitoring in Head and Neck Cancer Patients
In order to estimate the effect of fluid management in regard to postoperative complications this observatory study will document every kind of fluid intervention peri- and intraoperatively.
- Trial name
- HMHN (NCT02715310)
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Technical University of Munich
Heart Failure, Sudden Cardiac Death
Marathon, Genetics, Inflammation and the Cardiovascular System: MAGIC-Trial
The purpose of the study is to determine the myocardial function and vascular adaptation after strenuous exercise in association with genotype/polymorphisms.
- Trial name
- MAGIC (NCT00845286)
- Testing
- Munich Marathon
- Where
- Germany
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Gastrointestinal Stromal Tumors
Detection of CF-DNA in Patients With Gastrointestinal Stromal Tumors (GIST)
Activating mutations of the kinases CKIT or PDGFRA can be detected in 90% of cases by DNA sequence analysis of a pathological specimen.
- Trial name
- NCT01462994
- Testing
- Blood will be withdrawn at baseline and in intervals of 3 months for a total period of 2 years
- Where
- Germany
- Volunteers
- 25 people
- Sponsor
- Technical University of Munich