Clinical trials: sponsored by Technical University of Munich
Perfusion, Complication of Perfusion
Extracorporeal Perfusion of Microvascular Free Flaps
The perfusion of microvascular free flaps is inevitable for completion of reconstruction in the head and neck area. In some patients microvascular anastomosis is impossible because of arteriosclerotic changes, different…
- Trial name
- NCT02449525
- Testing
- Perfusion of flaps by a special bypass system
- Where
- Germany
- Volunteers
- 10 people
- Sponsor
- Technical University of Munich
Locally Advanced Head and Neck Cancer
Impact of Selective Radiation Dose Escalation and Tumour Hypoxia Status on Locoregional Tumour Control After Radiochemotherapy of HNT
The major clinical problem and predominant cause of death after radio-oncological treatment of H+N cancers are loco-regional relapses.
- Trial name
- Escalox (NCT01212354)
- Testing
- Radiotherapy
- Where
- Germany
- Volunteers
- 270 people
- Sponsor
- Technical University of Munich
Cancer
RandOmized Study Exploring the Combination of radioTherapy With Two Types of Acupuncture Treatment: The ROSETTA Trial
The ROSETTA-trial will evaluate the effect of acupuncture as a complementary treatment parallel to radiation therapy in oncological patients. The trial is designed as a two-armed trial.
- Trial name
- ROSETTA (NCT02674646)
- Testing
- Radiotherapy, Needle Acupuncture
- Volunteers
- 74 people
- Sponsor
- Technical University of Munich
End Stage Renal Disease, Chronic Kidney Disease
Risk Stratification in End Stage Renal Disease (ESRD) - ISAR Study
The purpose of this study is to evaluate the use of non-invasive markers of the autonomic function and micro- and macrocirculation to predict mortality and cardiovascular end points in end-stage renal disease patients.
- Conditions
- End Stage Renal Disease, Chronic Kidney Disease, Cardiovascular Event, Sudden Cardiac Death
- Trial name
- ISAR (NCT01152892)
- Where
- 17 sites in Germany
- Volunteers
- 500 people
- Sponsor
- Technical University of Munich
Radiographic Contrast Agent Nephropathy
Does Bicarbonate in Addition to Theophylline Reduce CIN?
Contrast-induced nephropathy (CIN) is the third most frequent cause of hospital-acquired acute renal failure. Different regimes in the prophylaxis of CIN have been investigated in the last years.
- Trial name
- NCT02643602
- Testing
- Hydration with bicarbonate in addition to theophylline, Hydration with sodium chloride in addition to theophylline
- Volunteers
- 152 people
- Sponsor
- Technical University of Munich
Colon Adenoma, Colorectal Carcinoma
Accuracy of the Optical Diagnosis of Small Colonic Polyps Using the Nice Classification
Adenomas and hyperplastic polyps are polypoid lesion and may occur at any location in the colon. At the present moment, all polyps should be resected endoscopically, although only adenomas, but not hyperplastic polyps have the…
- Conditions
- Colon Adenoma, Colorectal Carcinoma, Hyperplastic Polyp
- Trial name
- ADOPTION (NCT02009774)
- Testing
- NBI Function
- Where
- 3 sites in Germany
- Volunteers
- 380 people
- Sponsor
- Technical University of Munich
Failed Conscious Sedation During Procedure
Magnetic Endoscope Imaging in Colonoscopy: Influence on Propofol Dosage
Magnetic Endoscope Imaging (MEI) is an optional tool which can be switched on at the beginning of colonoscopy. MEI works by creating an electromagnetic field of very low intensity.
- Trial name
- MEXICO (NCT02121704)
- Testing
- Magnetic Endoscope Imaging (Scope Guide)
- Where
- Germany
- Volunteers
- 334 people
- Sponsor
- Technical University of Munich
Hypertension, Chronic Kidney Disease
Impact of Sympathetic Renal Denervation- a Study in Patients After Renal Transplantation
The study is aiming to document the safety and effectiveness of renal denervation in patients after renal transplantation with hypertension.
- Conditions
- Hypertension, Chronic Kidney Disease, Renal Transplantation, Sympathetic Activity
- Trial name
- ISAR-denerve (NCT01899456)
- Testing
- Catheter-based renal denervation
- Where
- Germany
- Volunteers
- 18 people
- Sponsor
- Technical University of Munich
Forearm Pronation Strength Recovery
Pronator Quadratus Repair After Volar Plating of Distal Radius Fractures
Investigation of the influence of the pronator quadratus (PQ) muscle repair following volar plate fixation of distal radius fractures with regard to the forearm pronation strength.
- Trial name
- NCT02595229
- Testing
- Pronator quadratus repair
- Volunteers
- 60 people
- Sponsor
- Technical University of Munich
Renal Insufficiency or Renal Failure &or End-stage Renal Disease
Cytokine Adsorption in Sepsis and Acute Kidney Injury
Aim of the study is to reduce the incidence of RIFLE stadium L and E after acute kidney injury in patients with severe sepsis/septic shock
- Trial name
- CASAKI (NCT02588794)
- Testing
- CytoSorb 300 ml device (3804606CE01)
- Where
- Germany
- Volunteers
- 124 people
- Sponsor
- Technical University of Munich
Acute Respiratory Distress Syndrome
Extracorporeal Lung Assist Device in Acute Lung Impairment
The purpose of this study is to compare the effect of interventional Lung Assist iLA activve to standard therapy in mechanically ventilated patients with severe acute lung impairment.
- Trial name
- EXODUS (NCT02550600)
- Testing
- iLA activve treatment, Control group
- Where
- 8 sites in Austria, Germany and 2 more
- Volunteers
- 300 people
- Sponsor
- Technical University of Munich
Gastrointestinal Neoplasms
Improvement of Colonoscopy Preparation by New Media (APP)
Feasibility of an newly programmed offline application for smartphones (SPA, APP) for colonoscopy preparation offering a 5 day guidance prior colonoscopy containing dietary- and behavioral recommendation.
- Trial name
- PERICLESAPPI (NCT02512328)
- Testing
- APP supported colonoscopy preparation
- Where
- Germany
- Volunteers
- 25 people
- Sponsor
- Technical University of Munich
Prostate Cancer
Detection of Micrometastases in Lymph Nodes of Patients With Prostate Cancer
The purpose of this study is to set up a model for detecting micrometastases in Lymph nodes of patients with prostate cancer by quantitative polymerase chain reaction and its impact on progression-free survival.
- Trial name
- NCT01615965
- Testing
- tumor marker detection in lymph nodes
- Where
- Germany
- Volunteers
- 160 people
- Sponsor
- Technical University of Munich
Recurrent Childhood Soft Tissue Sarcoma, Recurrent Ewing Sarcoma
Trabectedin and Irinotecan for Refractory Pediatric Sarcomas
The purpose of the study is to evaluate patients with refractory childhood sarcomas, who have been treated with a combination therapy of trabectedin and irinotecan (within compassionate use), to determine, if this is a promising…
- Conditions
- Recurrent Childhood Soft Tissue Sarcoma, Recurrent Ewing Sarcoma, Recurrent Rhabdomyosarcoma
- Trial name
- TrIPReSarc (NCT02509234)
- Testing
- Combined chemotherapy with trabectedin followed by irinotecan
- Volunteers
- 30 people
- Sponsor
- Technical University of Munich
Inflammation, Death, Sudden, Cardiac
The Effects of Enzymes and Flavonoids on Inflammation and Coagulation After Marathon
The aim of the present study is to investigate changes in inflammatory status and incidence of infection after extreme aerobic physical stress (participation in a marathon).
- Conditions
- Inflammation, Death, Sudden, Cardiac, Death, Heart Diseases
- Trial name
- Enzy-MagIC (NCT01916408)
- Testing
- Wobenzym plus, PL 1
- Where
- Germany
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Psychological Distress
Indication-based Identification and Psychosocial Treatment of Orthopedic Cancer Patients
Aim of this study is to develop and establish an indication-based algorithm for identifying particular stress patterns of patients with initial diagnosis of a sarcoma or a metastatic bone disease.
- Trial name
- NCT01631175
- Testing
- psychosocial treatment
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Technical University of Munich
Endothelial Function (Reactive Hyperemia)
MOVING - MOtiVation, INtervention and Vascular chanGe
Background: The impact of demographic changes on workplace has increased the importance of effective occupational preventive health programs.
- Trial name
- MOVING (NCT01919632)
- Testing
- health-behavior seminar and endurance exercise
- Where
- 2 sites in Germany
- Volunteers
- 330 people
- Sponsor
- Technical University of Munich
Postoperative Infection
Antibiotics in Free Flaps Reconstructions
The purpose of this study is to monitor and compare peri-operative problems and outcomes of reconstructive surgery with microvascular free flaps in the head and neck region between groups of patients treated with perioperative…
- Trial name
- NCT02436083
- Testing
- antibiotic (use of penicilline, unacid, cefuroxime)
- Volunteers
- 350 people
- Sponsor
- Technical University of Munich
Cardiac Death, Congestive Heart Failure
Correlation Between Reticulated Platelets and Major Adverse Cardiac and Cerebrovascular Events After Noncardiac Surgery
This is an observational study designed to monitor the course of the fraction of reticulated platelets and the correlation thereof to major adverse cardiac and cerebrovascular events after noncardiac surgery.
- Conditions
- Cardiac Death, Congestive Heart Failure, Angina Pectoris, Stroke
- Trial name
- NCT02097602
- Where
- Germany
- Volunteers
- 1,000 people
- Sponsor
- Technical University of Munich
Atypical Gastroesophageal Reflux Symptoms, Objectified Gastroesophageal Reflux Disease
Effect of Full-thickness Gastroplication With the GERD-X System on Atypical Gastro-esophageal-reflux-symptoms
Patients with atypical symptoms of objectified gastroesophageal reflux disease will be treated by full-thickness gastroplication and the effect of this intervention will be measured by questionnaires and clinical diagnostics (for…
- Trial name
- NCT02181855
- Testing
- Full-thickness gastroplication (GERD-X)
- Where
- 4 sites in Austria, Germany
- Volunteers
- 23 people
- Sponsor
- Technical University of Munich