Clinical trials: sponsored by Technical University of Munich
Atypical Gastroesophageal Reflux Symptoms, Objectified Gastroesophageal Reflux Disease
Effect of Full-thickness Gastroplication With the GERD-X System on Atypical Gastro-esophageal-reflux-symptoms
Patients with atypical symptoms of objectified gastroesophageal reflux disease will be treated by full-thickness gastroplication and the effect of this intervention will be measured by questionnaires and clinical diagnostics (for…
- Trial name
- NCT02181855
- Testing
- Full-thickness gastroplication (GERD-X)
- Where
- 4 sites in Austria, Germany
- Volunteers
- 23 people
- Sponsor
- Technical University of Munich
Magnetic Endoscope Imaging in Single-balloon-enteroscopy
Magnetic Endoscope Imaging in Single-balloon-enteroscopy
Magnetic endoscope imaging (MEI) is already used in colonoscopy in order facilitate scope navigation. In this study the use of MEI will be evaluated for small bowel enteroscopy in which scope navigation is particularly important.
- Trial name
- Magenta (NCT02184754)
- Testing
- Magnetic endoscope imaging (MEI)
- Where
- Germany
- Volunteers
- 10 people
- Sponsor
- Technical University of Munich
Coronary Artery Disease
The Effects of Combined Exercise Training on Exercise Capacity in Cardiac Rehabilitation
Seventy patients in cardiac rehabilitation with maximal exercise capacity less than 1.4 watt per kilogram bodyweight will be randomized 1:1 into either an intervention training (IN) group or usual care (UC).
- Trial name
- DOPPELHERZ (NCT01921036)
- Testing
- traditional cardiac rehabilitation, combined exercise
- Where
- Germany
- Volunteers
- 70 people
- Sponsor
- Technical University of Munich
Transcatheter Aortic Valve Replacement
Exercise Training After Transcatheter Aortic Valve Implantation
This pilot study will evaluate the effect of a rehabilitative exercise training on exercise capacity in patients after percutaneous aortic valve replacement.
- Trial name
- SPORT:TAVI (NCT01935297)
- Testing
- Exercise
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Technical University of Munich
Eosinophilic Esophagitis
Esophageal Motility in Eosinophilic Esophagitis Evaluated by High Resolution Manometry.
Esophageal Motility in eosinophilic esophagitis will be evaluated by High Resolution Manometry before and after medical treatment - motility is suspected to change/improve after therapy.
- Trial name
- HIMEOS (NCT02331849)
- Testing
- High resolution manometry (HRM)
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Technical University of Munich
Somatoform Vertigo/Dizziness
Tailored Care for Somatoform Vertigo/Dizziness
The purpose of this study is to evaluate the efficacy of a manualised, multimodal group psychotherapy, based on integrative psychotherapy (IPT) and tailored to somatoform vertigo/dizziness (SVD) subgroups of mental disorders…
- Trial name
- NCT02320851
- Testing
- SVD-tailored Integrative Psychotherapy (IPT), Self-help group (SHG)
- Volunteers
- 216 people
- Sponsor
- Technical University of Munich
Laxative Compatibility
Sodium Picosulfate Plus Magnesium Citrate Versus Macrogol 4000 in the Bowel Cleansing Procedure: a Comparison of Efficiency and Compatibility
For effective cleansing of the bowel prior to colonoscopy polyethylene glycol (e.g. macrogol) has widely been used in Germany. Usually patients have to drink between 4 an 6 liter of macrogol in a split dose (3 liter on the day…
- Trial name
- NCT01607099
- Testing
- Compatibility
- Where
- Germany
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Sedation Problems, Breathing Complications
Patient Positioning During Colonoscopy: Effects on Safety and Diagnostic Outcome
The purpose of this study is to determine the effects of patient positioning during colonoscopy on patient safety and diagnostic outcome.
- Trial name
- PACSO (NCT02001792)
- Testing
- Position the patient during colonoscopy, pulse oximeter
- Where
- 2 sites in Germany
- Volunteers
- 412 people
- Sponsor
- Technical University of Munich
Insulin Resistance
Changes in Insulin Resistance in Healthy Volunteers on STRIBILD® Medication
Changes in insulin resistance in healthy volunteers with normal body weight (BMI 18-25) after 14 days of STRIBILD®-, Truvada®/Kaletra® or Truvada®/Prezista®/Norvir® intake, measured by hyperinsulinemic euglycemic clamp.
- Trial name
- NCT02203461
- Testing
- Tenofovir disaproxil fumarate/emtricitabine/elvitegravir/cobicistat, Tenofovir disaproxil fumarate/emtricitabine + Lopinavir/ritonavir, Tenofovir disaproxil fumarate/emtricitabine + ritonavir-boosted darunavir
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Fracture, Closed, Comminuted, Healing
Treatment of Displaced Lateral Clavicle Fractures Using a Locking Compression Plate With Lateral Extension
Treatment of lateral fractures of the clavicle is challenging and has been controversially discussed for a long time due to high non-union rates in non-operative treatment and high complication rates in surgical treatment.
- Trial name
- LatClav (NCT02256059)
- Testing
- Plate osteosynthesis
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Technical University of Munich
Complication
Surgical Innovations in Treatment of Clavicle Fractures
Surgical incision for plate osteosynthesis of midshaft fractures of the clavicle averages 7 to 8 centimeters in the literature. It is hypothesized, that depending on the invasiveness of this incision secondary problems like…
- Trial name
- ClavFrac (NCT02247778)
- Testing
- conventional plate osteosynthesis, mini-incision-type osteosynthesis
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Technical University of Munich
Schizophrenia, Schizoaffective Disorder
How Can Rehospitalisations of Patients With Schizophrenia be Avoided? A Comparison Between Different Compliance Programs
Participation in one of the three interventions psychoeducation by professionals, psychoeducation by peer-moderators, or video-education can reduce the rehospitalisation rate of patients with schizophrenia compared to a control…
- Trial name
- NCT00514423
- Testing
- Psychoeducation by professonals, Psychoeducation by peer-moderators, Video-education
- Where
- Germany
- Volunteers
- 896 people
- Sponsor
- Technical University of Munich
Oral Lichen Planus
Impact of Continuous Defocused CO2 Laser Vaporisation on the Histological Malignant Transformation of Erosive Oral Lichen Planus in Patients
Oral Lichen Planus (OLP) is a common condition with its erosive variant occasionally presenting a management challenge to the clinician. In addition it can have debilitating consequences on the patients' quality of life.
- Trial name
- NCT02154607
- Testing
- CO2-Laser Treatment
- Volunteers
- 263 people
- Sponsor
- Technical University of Munich
Anesthesia, Drug Effects
Neural Mechanisms of Sevoflurane Induced Anesthesia: an EEG fMRI Study in Healthy Volunteers
In imaging functional connectivity (FC) analyses of the resting brain, alterations of FC during unconsciousness have been reported.
- Trial name
- NCT02149927
- Testing
- Sevoflurane
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Neuromuscular Blockade, Anesthesia
Rocuronium Dose Finding Study After Single-shot or Steady-state Propofol Anesthesia
This study is designed to determine the effective-doses ED-50 and ED-95 (the doses required for a 50% and 95% twitch inhibition, respectively) of the non-depolarizing muscle relaxant rocuronium after single-shot or steady-state…
- Trial name
- ROSANNA (NCT02054468)
- Testing
- Single-Shot Propofol, 30min infusion Propofol, Remifentanil infusion
- Where
- Germany
- Volunteers
- 82 people
- Sponsor
- Technical University of Munich
Esophageal Cancer
Cetuximab, Oxaliplatin, Fluorouracil, and Radiation Therapy in Treating Patients With Stage II or Stage III Esophageal Cancer
RATIONALE: Monoclonal antibodies, such as cetuximab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread.
- Trial name
- NCT00425425
- Testing
- cetuximab, fluorouracil, oxaliplatin
- Where
- 3 sites in Germany
- Volunteers
- 43 people
- Sponsor
- Technical University of Munich
Modes of Exercise and Myocardial and Endothelial Function, Microcirculation
Investigation of Cardiac Function and Cardiovascular Risk Factors in Marathon Runners- The Munich Marathon Study
The purpose of this study is to determine the cardiovascular risk involved in the exertional exercise of marathon running. The researchers aim to investigate the beneficial effects of regular well-dosed exercise on health and…
- Conditions
- Modes of Exercise and Myocardial and Endothelial Function, Microcirculation, Subclinical Endorgan Damage, Obesity
- Trial name
- MMS (NCT00500773)
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Obesity, Inactivity
IT-based Training in Obesity
Though possibly cost-saving, there is little scientific evidence for the effectiveness and reasonable modality of internet-delivered physical activity interventions in primary prevention.
- Trial name
- NCT00899964
- Testing
- Physical activity
- Where
- Germany
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Adenoma Detection Rate
Training Effects in Colonoscopy
Colon cancer is the second most common cause of death among cancer-related deaths in Germany. Precancerous lesions such as adenomas can be detected efficiently by colonoscopy.
- Trial name
- TraCo (NCT01786213)
- Where
- Germany
- Volunteers
- 3,500 people
- Sponsor
- Technical University of Munich
Overweight, Obesity
Fatty Acids During Pregnancy and Lactation and Body Fat Mass in Newborns
Pregnant and lactating women receive n-3 fatty acids starting from week 15 of gestation until 4 months post-partum (pp) in comparison to a control group, who only gets information about adequately healthy nutrition during…
- Trial name
- NCT00362089
- Testing
- Marinol D-40
- Where
- Germany
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich