Clinical trials: sponsored by Technical University of Munich
Quality of Life in Patients With Inflammatory Bowel Disease
Impact of Physical Exercise on Quality of Life in Patients With Inflammatory Bowel Disease - a Pilot Study.
Patients with inflammatory bowel disease (IBD) suffer from a diminished quality of life compared to healthy adults. This is due to the chronic course of disease accompanied with diarrhea, stomach pains but also with psychological…
- Trial name
- NCT01834573
- Testing
- physical exercise
- Where
- Germany
- Volunteers
- 36 people
- Sponsor
- Technical University of Munich
Knee Injury
The Munich Knee Questionnaire - Development and Validation
the purpose of this study is to develop and validate a new PRO measurement tool for the knee joint, the so-called Munich Knee Questionnaire (MKQ), allowing for a qualitative self-assessment of the Knee Injury and Osteoarthritis…
- Trial name
- MKQ (NCT01950208)
- Where
- Germany
- Volunteers
- 105 people
- Sponsor
- Technical University of Munich
Type 1 Diabetes, Children
Cord Blood Infusion for Type 1 Diabetes Mellitus (T1DM)
Type 1 diabetes (T1D) is still associated with tremendous morbidity and premature mortality. Patients require multiple daily insulin injections throughout their lives as well as close monitoring of their diet and blood sugar…
- Trial name
- NCT00989547
- Testing
- Umbilical Cord Blood VITA 34
- Where
- Germany
- Volunteers
- 18 people
- Sponsor
- Technical University of Munich
Globus Sensations in the Throat
Long Term Outcome of Argon Plasma Coagulation of Cervical Heterotopic Gastric Mucosa as an Alternative Treatment for Globus Sensations
APC of gastric inlet patches is successful for the treatment of globus sensations in the throat (Bajbouj et al Gastroenterology 2009; 137:440-4). There is no data for long term efficiency of this treatment.
- Trial name
- ACHAT FU (NCT01574755)
- Volunteers
- 49 people
- Sponsor
- Technical University of Munich
Metastatic Gastric Cancer
Histone Deacetylases - Gastric Cancer (HDAC-GaCa-2008)
This is an open-label, phase II trial evaluating the antitumor activity and safety of the oral Histone Deacetylase (HDAC)-Inhibitor LBH589.
- Trial name
- HDAC (NCT01528501)
- Testing
- Panobinostat (LBH589)
- Where
- 2 sites in Germany
- Volunteers
- 28 people
- Sponsor
- Technical University of Munich
Chronic Diabetic Foot Ulcers
Shockwave Treatment of Diabetic Foot Ulcer: Step I
Extracorporeal Shock Wave treatment is a well established treatment in orthopedics. Considerable success has been reported after treatment of various soft tissue pathologies (Tendinitis, heel spur etc).
- Trial name
- STUF (NCT00954343)
- Testing
- Extracorporeal Shock Wave
- Where
- Germany
- Sponsor
- Technical University of Munich
Neuromuscular Block
Sugammadex and Neostigmine at Shallow Neuromuscular Blockade
This study is designed to compare recovery times after reversal of a residual neuromuscular block (TOF-ratio 0.5) with different doses of either neostigmine or sugammadex.
- Trial name
- SUNDRO (NCT00895609)
- Testing
- Sugammadex, Neostigmine, Saline
- Where
- Germany
- Volunteers
- 99 people
- Sponsor
- Technical University of Munich
Gastric Cancer
Imatinib, Capecitabine, and Cisplatin in Treating Patients With Unresectable or Metastatic Stomach Cancer
RATIONALE: Imatinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as capecitabine and cisplatin, work in different ways to stop the growth of tumor…
- Trial name
- NCT00601510
- Testing
- capecitabine, cisplatin, imatinib mesylate
- Where
- Germany
- Volunteers
- 38 people
- Sponsor
- Technical University of Munich
Neuromuscular Blockade
Neuromuscular Blockade Improves Surgical Conditions
This study is designed to test the clinical hypothesis that a neuromuscular block improves surgical conditions, operation time, and post-operative pain.
- Trial name
- NISCO (NCT00895778)
- Testing
- Neuromuscular blockade with rocuronium and reversal with sugammadex
- Where
- Germany
- Volunteers
- 57 people
- Sponsor
- Technical University of Munich
Autoimmune Pancreatitis
EUS-guided Procore-biopsy in Diagnosing Autoimmune Pancreatitis
The goal of this prospective study is to evaluate the feasibility of the Core Biopsy Needle with reverse bevel (Procore TM) in diagnosing autoimmune pancretitis
- Trial name
- NCT01774513
- Testing
- Procore-Needle
- Where
- Germany
- Volunteers
- 16 people
- Sponsor
- Technical University of Munich
Major Non-cardiac Surgery
Goal Directed Hemodynamic Management and Renal Outcome After Major Non-cardiac Surgery
This study is designed to compare renal outcome of patients following major non-cardiac surgery with different perioperative hemodynamic managements: a goal directed hemodynamic management group (using PiCCO) and a control group.
- Trial name
- IROM (NCT01035541)
- Testing
- PiCCO® Monitoring
- Where
- Germany
- Volunteers
- 180 people
- Sponsor
- Technical University of Munich
Neuromuscular Blockade
Sugammadex Improves Muscle Function After Standard Neuromuscular Recovery
This study is designed to investigate, whether Sugammadex improves muscle function after standard neuromuscular recovery (TOF 0.9) from relaxation with rocuronium.
- Trial name
- NCT01101139
- Testing
- Sugammadex
- Where
- Germany
- Volunteers
- 300 people
- Sponsor
- Technical University of Munich
Lymphoma
Everolimus in Treating Older Patients With Mantle Cell Lymphoma Previously Treated With First-Line or Second-Line Chemotherapy
RATIONALE: Everolimus may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. PURPOSE: This phase II trial is studying how well everolimus works in treating older patients with mantle cell…
- Trial name
- NCT00727207
- Testing
- everolimus
- Where
- Germany
- Volunteers
- 35 people
- Sponsor
- Technical University of Munich
Residual Neuromuscular Block (TOF-ratio of 0.2)
Sugammadex and Neostigmine at Residual Neuromuscular Blockade
This study is designed to compare recovery times after reversal of a residual neuromuscular block (TOF-ratio 0.2) with different doses of either neostigmine or sugammadex.
- Trial name
- SUNDRO20 (NCT01006720)
- Testing
- Sugammadex, Neostigmine, Saline
- Where
- Germany
- Volunteers
- 99 people
- Sponsor
- Technical University of Munich
Pancreatic Cancer
Stereotactic Radiation Therapy and Combination Chemotherapy in Treating Patients Undergoing Surgery for Locally Advanced Pancreatic Cancer
RATIONALE: Stereotactic radiation therapy may be able to send x-rays directly to the tumor and cause less damage to normal tissue.
- Trial name
- NCT00425841
- Testing
- gemcitabine hydrochloride, oxaliplatin, adjuvant therapy
- Where
- Germany
- Volunteers
- 29 people
- Sponsor
- Technical University of Munich
Subepithelial Tumors of the Upper Gastrointestinal Tract
22-G-Procore Needle for the Diagnosis of SETs of the Upper GI Tract
The goal of this prospective study is to evaluate the feasibility of the 22-G Core Biopsy Needle with reverse bevel (Procore TM) in biopsy sampling of subepithelial tumors of the upper gastrointestinal tract.
- Trial name
- PRO-SET (NCT01726010)
- Testing
- 22-G Procore Needle
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Technical University of Munich
Anesthesia, Electroencephalography/ Drug Effect
Detection of Consciousness by EEG and Auditory Evoked Potentials
The objective of the present investigation is to analyze EEG and auditory evoked potentials at the transition from consciousness to unconsciousness and vice versa.
- Trial name
- NCT01720615
- Testing
- Propofol / Remifentanil, Sevoflurane / Remifentanil
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- Technical University of Munich
Pancreatic Cancer
Resection in Pancreatic Cancer With Minimal Metastatic Disease or Venous Infiltration Trial at Technische Universität München
PaMeViTUM is a mono-centric prospective randomized controlled trial that compares different operating procedures in patients with pancreatic cancer and minimal metastatic disease or venous infiltration.
- Trial name
- PaMeViTUM (NCT00855634)
- Testing
- Resection of metastases, Resection of infiltrated veins
- Where
- Germany
- Volunteers
- 355 people
- Sponsor
- Technical University of Munich
Lymphoma
Rituximab, Fludarabine, Cyclophosphamide, and Yttrium Y 90 Ibritumomab Tiuxetan in Treating Patients With Relapsed B-Cell Non-Hodgkin's Lymphoma
RATIONALE: Monoclonal antibodies, such as rituximab, can block cancer growth in different ways. Some block the ability of cancer cells to grow and spread.
- Trial name
- NCT00397800
- Testing
- rituximab, cyclophosphamide, fludarabine phosphate
- Where
- 12 sites in Germany
- Volunteers
- 12 people
- Sponsor
- Technical University of Munich
Gastrointestinal Endoscopy, Sedation
Bispectral Index Monitoring of Sedation During Endoscopic Retrograde Cholangiopancreaticography
This randomized study investigates the benefits of an additional Bispectral Index monitoring of depth of sedation during endoscopic retrograde cholangiopancreaticography.
- Trial name
- EndoBISs (NCT00952458)
- Testing
- BIS monitoring
- Where
- Germany
- Volunteers
- 144 people
- Sponsor
- Technical University of Munich