Clinical trials: sponsored by Technical University of Munich
Prediction of Volume Responsiveness
SMOOCH - Small Volume Challenges to Predict Volume Responsiveness: Prospective Interventional Study
test for volume responsiveness PiCCO-guided infusion over a pre-defined period of time
- Trial name
- SMOOCH (NCT01227304)
- Testing
- PiCCO-parameter-guided volume challenge
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Technical University of Munich
Inflammation, Heart Failure
Beer, Marathon, Genetics, Inflammation and the Cardiovascular System: Be-MaGIC-Trial
The purpose of the study is to determine the myocardial function and vascular adaptation after strenuous exercise in association with consumption of polyphenols.
- Conditions
- Inflammation, Heart Failure, Sudden Cardiac Death
- Trial name
- Be-MaGIC (NCT00933218)
- Testing
- polyphenols (non-alcoholic beer), beverage without polyphenols
- Where
- Germany
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Post-Traumatic Stress Disorder
Study of Eye Movement Desensitization and Reprocessing (EMDR) Working Mechanism
EMDR (Eye Movement Desensitization and Reprocessing) is an exposure-based procedure for the treatment of patients with post-traumatic stress disorder (PTSD).
- Trial name
- NCT01209377
- Testing
- standard, fixed, no focus
- Where
- Germany
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Schizophrenia
Shared Decision Making for Schizophrenia
The impact of a decision aid for inpatients with schizophrenia on perceived involvement and compliance is studied in comparison with routine care.
- Trial name
- NCT00220870
- Testing
- Decision aid
- Where
- Germany
- Sponsor
- Technical University of Munich
Abdominal Pain
Endosonography For Right Side Acute Intestinal Mal-Symptoms (EFRAIM- Study)
Hypothesis: Endosonography (EUS) in a single setting is equivalent to the standard algorithm combining abdominal sonography, gastroscopy, endosonography in patients with acute right side abdominal pain.
- Trial name
- EFRAIM (NCT01080690)
- Testing
- EGD, EUS
- Where
- Germany
- Volunteers
- 240 people
- Sponsor
- Technical University of Munich
Association of Heterotopic Gastric Mucosa of the Cervical Esophagus and Globus Sensations
Prevalence of Gastric Inlet Patches of the Cervical Esophagus.
As known from several observational and retrospective endoscopic studies the prevalence of gastric inlet patches (GIPs) of the cervical esophagus is estimated between 1-10%.
- Trial name
- NCT01056003
- Testing
- Endoscopy
- Where
- Germany
- Volunteers
- 4,000 people
- Sponsor
- Technical University of Munich
Grafting, Renal Transplantation
Value of Rituximab in Humoral Chronic Rejection After Renal Transplantation
To evaluate the benefit of rituximab in patients with CAN with histologically proven C4d deposits and/or plasma cell and/or B-Lymphocyte (CD20+ cells) infiltration of their grafts.
- Conditions
- Grafting, Renal Transplantation, Transplantation, Kidney, Chronic Allograft Nephropathy
- Trial name
- Rituximab 2006 (NCT00568477)
- Testing
- MabThera
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Technical University of Munich
Coronary Circulation
Suggestive Effects on the Diameter of Coronary Arteries
The aim of this randomized controlled pilot study was to answer the following questions: 1. Is it possible to affect the diameter of coronary arteries through a placebo injection, which is administered intracoronarily together…
- Trial name
- SUGO-KO (NCT00925834)
- Testing
- Verbal suggestions
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Technical University of Munich
Metabolic Syndrome
IT-Based Training in Metabolic Syndrome
Prospective, randomized, single center, controlled intervention study to investigate the effect of a systematic combined personal and IT-based training on the outcome of patients with metabolic syndrome.
- Trial name
- SPRINT (NCT00686244)
- Testing
- Combined 3-monthly endurance and strength training
- Where
- Germany
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Valvular Aortic Stenosis
Physical Activity in Patients After Aortic Valve Replacement (Valve-ex)
A structured and supervised, 3-month physical activity intervention in patients after aortic valve replacement due to severe stenosis, accompanied by examination of cardiac size and function, exercise capacity and endothelial…
- Trial name
- NCT00860678
- Testing
- Physical activity, no Intervention
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Technical University of Munich
Barrett Esophagus
Confocal Laserscanning Microscopy for Detection of Barretts Esophagus
Four quadrant biopsies in regular ranges is the goldstandard in monitoring this disease. The ideal situation for the endoscopist is to visualize cellular structures, which implies having microscopic imaging available.
- Trial name
- NCT00449995
- Testing
- confocal laser microscopy
- Where
- Germany
- Volunteers
- 73 people
- Sponsor
- Technical University of Munich
Postoperative Residual Curarization
Muscle Relaxants and Post-Anesthesia Complications
This Germany-wide, multi-center, epidemiologic study is designed to evaluate the incidence of post-operative/anesthesia effects of muscle relaxants (i.e.
- Trial name
- PORC (NCT00753389)
- Testing
- None (anesthesia)
- Where
- Germany
- Volunteers
- 20,000 people
- Sponsor
- Technical University of Munich
Globus, Deglutition Disorders
ACHAT-STUDY, Alternative Treatment of Chronic Globus Sensations
Globus sensations are associated with gastroesophageal reflux disease as well as the presence of a gastric inlet patch. No controlled trial exists on whether ablation of the cervical heterotopic mucosa may lead to improvement of…
- Trial name
- NCT00439439
- Testing
- Beamer Ablation (Argon Plasma Coagulation)
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Technical University of Munich
Patients With Persistent Objectified Gastroesophageal Reflux and Reflux-Associated Symptoms Despite PPI-Therapy With 40mg Esomeprazole
High Dosage Esomeprazole and Baclofen for Therapy of Gastroesophageal Reflux Disease
It has been reported that Baclofen is an appropriate tool in the therapeutic management of Gastroesophageal Reflux Disease. To objectify gastroesophageal reflux combined pH-metry/impedance monitoring was applied to patients with…
- Trial name
- NEXBAC (NCT00461604)
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Technical University of Munich
Breast Cancer
Nipple Areola Complex Conservation
96 patients were offered a nipple sparing mastectomy.
- Trial name
- NCT00641628
- Testing
- mastectomy
- Where
- Germany
- Sponsor
- Technical University of Munich
Healthy
Anesthetics and Auditory, Visceral, and Heat Evoked Potentials
The aim of the present study is to investigate and quantify the influence of commonly used anesthetics on auditory and pain evoked potentials.
- Trial name
- NCT00534586
- Testing
- Propofol, Remifentanil, S-Ketamine
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Contrast Induced Nephropathy, Kidney Diseases
Acetylcysteine, Theophylline, and a Combination of Both in the Prophylaxis of Contrast-Induced Nephropathy
Several studies demonstrated a significant reduction of contrast-induced nephropathy (CIN; definition: increase in serum creatinine of >=0.5mg/dl and/or >=25% increase within 48h after contrast-medium) by acetylcysteine (A) or…
- Conditions
- Contrast Induced Nephropathy, Kidney Diseases, Renal Failure, Adverse Effects
- Trial name
- ATHENS (NCT00492518)
- Testing
- Acetylcysteine, Theophylline
- Where
- Germany
- Volunteers
- 254 people
- Sponsor
- Technical University of Munich
Healthy
EEG and Auditory Evoked Potentials During Local Anesthesia
The aim of the present study was to investigate the sensitivity of AEP (auditory evoked potentials) to muscular artefacts using sedation and local anesthesia.
- Trial name
- NCT00408941
- Testing
- Propofol, Prilocaine
- Where
- Germany
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Elective Surgery, Healthy
The Influence of Injection Rate on EEG Propofol Peak Effect as Measured by Bispectral Index
The aim of the present study was to investigate whether injection rate of propofol has an influence on its maximum effect.
- Trial name
- NCT00290108
- Testing
- Propofol
- Where
- Germany
- Volunteers
- 99 people
- Sponsor
- Technical University of Munich