Clinical trials: sponsored by Technical University of Munich
Transcranial Magnetic Stimulation, Repetitive
Impact of nrTMS Therapy on the Progress of Neurorehabilitation
Low-frequency navigated repetitive transcranial magnetic stimulation (nrTMS) of the non-damaged hemisphere to increase cortical excitability of the damaged hemisphere and to reduce the increased neuronal inhibition in patients…
- Trial name
- NCT03982329
- Testing
- navigated repetitive transcranial magnetic stimulation, physical therapy
- Where
- Germany
- Volunteers
- 39 people
- Sponsor
- Technical University of Munich
Colon Polyp
Endocuff Vision Assisted vs. Standard Polyp Resection in the Colorectum
Adenomas are premalignant polyps of the colon that should be resected endoscopically. Complete resection of adenomatous polyps is the major task of colonoscopy.
- Trial name
- EVASTA (NCT03117114)
- Testing
- Endocuff Vision assisted polypectomy, Standard polypectomy
- Where
- Germany
- Volunteers
- 250 people
- Sponsor
- Technical University of Munich
Obstructive Sleep Apnea of Adult
Change in Tongue Strength and Fatigue After Upper Airway Stimulation Therapy
Upper airway stimulation (UAS) is an effective surgical alternative for patients with obstructive sleep apnea (OSA) who fail continuous positive airway pressure (CPAP) therapy.
- Trial name
- NCT03980158
- Where
- Germany
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Advanced Dementia
Advanced Dementia and End-of-life
Palliative and hospice care in advanced dementia: experiences of care givers and benefit of a brochure serving as a decision-making aid Aims: 1.
- Trial name
- NCT03548142
- Testing
- provision of relevant information
- Where
- Germany
- Volunteers
- 38 people
- Sponsor
- Technical University of Munich
Valvular Heart Disease
Valvular Heart Disease Registry
Patients undergoing transcatheter valvular interventions will be prospectively included into the present registry. Baseline, procedural and follow-up data will be collected and analyzed to adress various issues in the field of…
- Trial name
- NCT03488732
- Testing
- Transcatheter valvular repair or replacement
- Where
- Germany
- Volunteers
- 2,000 people
- Sponsor
- Technical University of Munich
Sarcoma, Soft Tissue
Radiomics for Tumor Grading of Soft Tissue Sarcomas.
Radiomics is defined as a quantitative high-throughput analysis of imaging data combined with model development aiming to predict biological correlates or clinical endpoints.
- Trial name
- NCT03798795
- Where
- Germany
- Volunteers
- 285 people
- Sponsor
- Technical University of Munich
Aneurysmal Subarachnoid Haemorrhage, SAH
Goal Directed Therapy After Aneurysmal Subarachnoid Haemorrhage
The objective of this study is to determine whether a goal-directed therapy can reduce the incidence of delayed cerebral ischaemia after aneurysmal subarachnoid haemorrhage.
- Trial name
- PiSAH (NCT01832389)
- Testing
- PiCCO
- Where
- Germany
- Volunteers
- 108 people
- Sponsor
- Technical University of Munich
Critical Care, Rehabilitation
Differences in Frail and Non-frail Critically-ill Patients in Functional Outcomes
This is a prospective analysis of patient registry data of intensive care patients. The aim is to investigate if frailty is a predictor of decline of functional status of critically ill patients during their hospital stay.
- Conditions
- Critical Care, Rehabilitation, Outcome Assessment, Critical Illness
- Trial name
- DEFAULT (NCT03789305)
- Where
- Germany
- Volunteers
- 731 people
- Sponsor
- Technical University of Munich
Delirium, Critical Illness
FAM-CAM Translation and Validation Into German
Validation and Translation of the Family Confusion Assessment Method (FAM-CAM) into German according to Principles of Good Practice for the Translation and Cultural Adaptation Process for Patient-Reported Outcomes of the…
- Conditions
- Delirium, Critical Illness, Family Members
- Trial name
- TRAVAGE-FAM (NCT03732443)
- Testing
- FAM-CAM
- Where
- Germany
- Sponsor
- Technical University of Munich
Soft Tissue Sarcoma of the Limb, AJCC Stage II and III
Preoperative Radiotherapy for Sarcomas of the Extremities With Intensity-Modulation, Image-Guidance and Small Safety-margins
RATIONALE: Modern radiotherapy techniques in a neoadjuvant setting have the potential to minimize morbidity and maximize efficacy.
- Trial name
- PREMISS (NCT01552239)
- Testing
- IMRT/IGRT, Tumor resection, Brachytherapy
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Technical University of Munich
Schizophrenia, Schizophrenia and Disorders With Psychotic Features
Evaluation of the Necessity of Long-term Pharmacological Treatment With Antipsychotics in Schizophrenic Patients
The main objective of the trial is to evaluate, how long an antipsychotic relapse-prevention should be continued and to which time a patient with schizophrenia is protected enough, so that a withdrawal or reduction of the…
- Conditions
- Schizophrenia, Schizophrenia and Disorders With Psychotic Features, Schizoaffective Disorders
- Trial name
- NCT02307396
- Testing
- Olanzapine, Amisulpride, Risperidone
- Where
- Germany
- Volunteers
- 21 people
- Sponsor
- Technical University of Munich
Colon Adenoma, Colorectal Carcinoma
NBI Versus White Light Endoscopy for Optical Characterization of Neoplastic Polyps in the Colorectum
Adenomas, serrated adenomas and hyperplastic polyps are polypoid lesion in the colorectum. At the present moment, all polyps should be resected endoscopically, although only adenomas and serrated adenomas, but not hyperplastic…
- Conditions
- Colon Adenoma, Colorectal Carcinoma, Hyperplastic Polyp, Serrated Adenoma
- Trial name
- ADOPTION II (NCT03679429)
- Testing
- NBI Function
- Where
- 3 sites in Germany
- Volunteers
- 370 people
- Sponsor
- Technical University of Munich
Immunosuppression After Kidney Transplantation
PEL-1235_REN-0176-I (Pelicon)
Aim of this study is to investigate whether in patients following kidney transplantation (>6 months after transplantation), the intra-patient variability of levels of tacrolimus is comparable after administration of tacrolimus…
- Trial name
- Pelicon (NCT01904045)
- Testing
- tacrolimus Advagraf, tacrolimus Prograf
- Where
- Germany
- Volunteers
- 51 people
- Sponsor
- Technical University of Munich
Critical Care, Rehabilitation
Influence of the Initial Level of Consciousness on Early, Goal-directed Mobilization
Analysis of the randomized controlled SOMS trial of early, goal-directed mobilization to investigate if the treatment effect is consistent and independent of the initial conscious state without evidence of moderation or…
- Trial name
- SOMS-GCS (NCT03666338)
- Testing
- Early, goal-directed mobilization
- Volunteers
- 200 people
- Sponsor
- Technical University of Munich
Degeneration of Lumbar Intervertebral Disc
Dynamic Stabilization Versus Fusion
The purpose of this study is to compare posterior dynamic stabilization with fusion in the treatment of lumbar degenerative disease.
- Trial name
- DYNORFUSE (NCT01365754)
- Testing
- standard, new
- Where
- Germany
- Volunteers
- 440 people
- Sponsor
- Technical University of Munich
Anesthesia
Validation of a Multimodal Indicator of Depth of Anesthesia
The present study is designed to validate an multimodal indicator of anesthetic depth (Schneider G et al. 2014, Anesthesiology 120, 819-28). The indicator previously developed shall now be tested on an independent set of data.
- Trial name
- NCT02742012
- Testing
- the study is observational
- Where
- 3 sites in Germany
- Volunteers
- 257 people
- Sponsor
- Technical University of Munich
Immature Platelets, Deep Venous Thrombosis
Immature Plateletes in the Etiopathology of Deep Venous Thrombosis
The study is designed to evaluate the role of platelets and immature platelets in the ethiopathology of deep venous thrombosis and pulmonary embolism.
- Trial name
- iPLATELET (NCT02361294)
- Testing
- Blood samples
- Where
- Germany
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Proximal Femoral Fracture
Multimodal Approach to Improve the Outcome of Patients With a Proximal Femoral Fracture
This study is designed to compare the outcome of patients with proximal femoral fractures with different perioperative regimes: a group with a multimodal intervention and a control group.
- Trial name
- FEMO (NCT01673776)
- Testing
- PulsioFlex® Monitoring
- Where
- Germany
- Volunteers
- 132 people
- Sponsor
- Technical University of Munich
Colonic Polyps
Computer Assisted Detection & Selection of Serrated Adenomas and Neoplastic Polyps - a New Clinical DRAft
The aim of the study is to develop a computer program which is able to automatically detect colorectal polyps in endoscopic video sequences.
- Trial name
- CASSANDRA II (NCT03601065)
- Testing
- Videos of polyps, resection of polyps
- Where
- Germany
- Volunteers
- 250 people
- Sponsor
- Technical University of Munich
Polyps, Adenoma Colon
Computer Assisted Selection of Serrated Adenomas and Neoplastic Polyps - a New Clinical DRAft
The aim of the study is to develop a computer program which is able to classify different entities of colorectal polyps on the basis of optical polyp features.
- Conditions
- Polyps, Adenoma Colon, Automatic Judgement, Colonic Neoplasms
- Trial name
- CASSANDRA I (NCT03550625)
- Testing
- Computer program
- Volunteers
- 300 people
- Sponsor
- Technical University of Munich