Clinical trials: sponsored by The Cleveland Clinic
Chronic Systolic Heart Failure (Dilated Cardiomyopathy)
NORDIC: Nitric Oxide-Derived Oxidants and Regional Endothelial and Diastolic Dysfunction in Dilated Cardiomyopathy
The principal aim is to investigate the safety and efficacy of rosiglitazone in patients with chronic systolic heart (Dilated cardiomyopathy).
- Trial name
- NORDIC (NCT00293137)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- The Cleveland Clinic
Acute Myocardial Infarction
A Phase I - II Safety Study of Filgrastim (Neupogen) to Improve Left Ventricular Function After Severe Acute Myocardial Infarction
The objective is to obtain initial information regarding the safety and efficacy of the use of Filgrastim in the setting of acute myocardial infarction.
- Trial name
- NCT00215124
- Testing
- Filgrastim
- Where
- United States
- Sponsor
- The Cleveland Clinic
Peripheral Vascular Disease
FIRE-PAD: Functional Improvement Through Revascularization of the Extremities for Peripheral Arterial Disease
The specific aims of the project are as follows: To determine whether catheter-based revascularization procedures improve functional capacity and quality of life among patients with intermittent claudication.
- Trial name
- NCT00274157
- Testing
- Behavior, diet control, smoking cessation, exercize
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- The Cleveland Clinic
Aortic Stenosis
Speckle Tracking Imaging in Patients With Low Ejection Fraction Aortic Stenosis (SPArKLE-AS)
In patients with aortic stenosis and low ejection fraction, how can we predict who will recover their ejection fraction after aortic valve replacement? We plan to observe 50 patients with Low EF aortic stenosis and perform serial…
- Trial name
- SPArKLE-AS (NCT00535899)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- The Cleveland Clinic
Coronary Artery Disease, Inflammatory Response
Trial to Study the Effects of Supplementary Omega-3 on Serum C-Reactive Protein Levels
To study the anti-inflammatory effects of marine omega-3 fatty acids, also known as n-3 polyunsaturated fatty acids (PUFA), we propose a randomized, double-blinded, prospective, single-center trial to examine the effect of…
- Conditions
- Coronary Artery Disease, Inflammatory Response, Atherosclerosis
- Trial name
- Omega-3 (NCT00578578)
- Testing
- eicosapentaenoic acid (EPA),
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- The Cleveland Clinic
Mechanical Valve Replacement, Warfarin Therapy
ABRIDGE: Low Molecular Weight Heparin in Bridging Patients After Mechanical Valve Replacement
The primary aim is to determine the rate of major bleeding and blood clots when using enoxaparin as a bridge to oral blood thinning medication in patients who have undergone mechanical valve replacement.
- Trial name
- NCT00298285
- Testing
- enoxaparin
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- The Cleveland Clinic
Peripheral Arterial Disease
Validation of a Correction Factor for Measurement of an Accurate Ankle-Brachial Index in the Seated Position
The purpose of this study is to test a correction factor which would allow ankle brachial indexes taken in the seated position to accurately predict an ankle brachial index taken in the supine position.
- Trial name
- NCT00452309
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- The Cleveland Clinic
Atrial Fibrillation
Assessment of Cardioversion Using Transesophageal Echocardiography II (ACUTE II)
SPECIFIC AIM: To test the safety and feasibility of using low molecular weight heparin (LMWH, enoxaparin sodium; Lovenox, Sanofi-Aventis) in lieu of unfractionated heparin (UFH) as antithrombotic therapy for patients in atrial…
- Trial name
- NCT00289042
- Testing
- Enoxaparin
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- The Cleveland Clinic
Influenza
Influenza Vaccination in Bone Marrow Transplantation
The purpose of this study is to determine whether influenza vaccination protects patients who receive a certain type of bone marrow transplantation.
- Trial name
- NCT00419224
- Testing
- inactivated split-virus influenza vaccine
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Common Cold, Gastroenteritis
Echinacea, Propolis and Vitamin C for URI Prevention in Preschoolers
We hypothesize the herbal preparation will enhance the preschoolers' immune response and when taken prophylactically for 12 weeks will decrease episodes of upper respiratory infections and gastroenteritis in the active versus the…
- Trial name
- NCT00231218
- Testing
- dietary supplement--echinacea, propolis, and vitamin c
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Influenza
Improving Influenza Vaccination Rates Among Health Care Professionals
The purpose of this study was to see if reminder letters and a large raffle prize would encourage health care workers to receive influenza vaccinations.
- Trial name
- NCT00404664
- Testing
- influenza vaccine, reminders letters, raffle prize
- Where
- United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic