Clinical trials: sponsored by Thomas Jefferson University
Sickle Cell Disease, HEMOGLOBIN SS
A Randomized Trial of LOVAZA in Pediatric Sickle Cell Disease (SCD)
The purpose of the study is to determine the effectiveness of LOVAZA (fish oil capsules) to decrease inflammation in children and adolescents with Sickle Cell Disease (SCD).
- Conditions
- Sickle Cell Disease, HEMOGLOBIN SS, Hemoglobin S Beta-0 Thalassemia, Inflammation
- Trial name
- NCT01202812
- Testing
- Omega-3 Fatty Acids: Eicosapentaenoic Acid (EPA) and Docosahexaenoic Acid (DHA)
- Where
- 2 sites in United States
- Volunteers
- 48 people
- Sponsor
- Thomas Jefferson University
Diabetes, Diabetes Mellitus
Computer-Assisted Cancer Risk Behavior Counseling
To test whether or not giving patients information before their doctor visits changes the care they receive and what type of information is best to give before the doctor visit.
- Conditions
- Diabetes, Diabetes Mellitus, Hypertension
- Trial name
- NCT00242645
- Testing
- Health Information, Preventive Services, Computer tailored information
- Volunteers
- 200 people
- Sponsor
- Thomas Jefferson University
Alzheimer's Disease
Project TAP: Tailored Activities Project
Specific Aims 1. Establish a preliminary effect size for the impact of the intervention on depressive affect and agitated behaviors in persons with dementia in 4 months 2.
- Trial name
- NCT00259467
- Testing
- Home-Based Behavorial Intervention
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Thomas Jefferson University
Heart Failure, Congestive, Cardiac Pacemaker, Artificial
Optivol Diagnostic Data for Discharge in Heart Failure
The objective of this study is to evaluate whether the heart rate variability, daily heart rate, and/or intrathoracic impedance recorded by implantable cardiac devices can be used in conjunction with other traditional clinical…
- Trial name
- 3DHF (NCT00420108)
- Where
- 5 sites in United States
- Volunteers
- 23 people
- Sponsor
- Thomas Jefferson University
Heart Failure
Measuring G Protein-coupled Receptor Kinase-2 (GRK2) in the Blood to Diagnose and Treat Patients With Heart Failure
The primary objective of this study is to determine the utility of GRK2 to differentiate between normal patients and patient groups that differ by the presence/absence of HF symptoms, systolic or diastolic left ventricular…
- Trial name
- NCT00419965
- Where
- United States
- Volunteers
- 582 people
- Sponsor
- Thomas Jefferson University
Dementia, Alzheimer Type
Project COPE:Managing Dementia at Home
This study tests the effectiveness of an in-home intervention to reduce upset and burden among family caregivers, and decrease nursing home placement.
- Trial name
- NCT00259454
- Testing
- In-home intervention
- Where
- United States
- Volunteers
- 278 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Analgesia
Postoperative Analgesia After Shoulder Replacement
A comparison was made regarding opioid analgesic usage immediately after elective shoulder replacement and for seven days at home between patients randomly given either 0.5% or 0.75% ropivacaine via interscalene block prior to…
- Trial name
- NCT01003860
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
HIV Infections
Safety Study of Elvucitabine in HIV-1 Subjects
The purpose of this 28 day study is to assess the viral kinetics and safety of elvucitabine.
- Trial name
- NCT00405249
- Testing
- elvucitabine
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Thomas Jefferson University
Cluster Headache
A Double-Blind, Placebo-Controlled Study Examining the Use of Topiramate in the Treatment of Cluster Headache
Topiramate is a medication that has been approved by the Food and Drug Administration (FDA) for the treatment of patients with seizures. The trade name for this drug is Topamax®.
- Trial name
- NCT00203190
- Testing
- Topiramate
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Thomas Jefferson University
Migraine
A Research Study To Compare Two Kinds Of Daily Headache
Chronic daily headache has been classified into several categories. One category is of sudden onset and is called New Daily Persistent Headache (NDPH).
- Trial name
- NCT00335803
- Where
- United States
- Sponsor
- Thomas Jefferson University
Migraine
Research Study Examining Nerve Block for Migraine
Migraine and the skin sensitivity that accompanies it can go away in minutes after a nerve block, which is a procedure involving an injection of a small amount of a local anesthetic next to a nerve to the skin, causing an area of…
- Trial name
- NCT00203346
- Testing
- Greater Occipital Nerve Block
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Thomas Jefferson University
Migraine Headache
Clinical Study Examining Use of an Over-the-Counter Supplement for the Prevention of Menstrually-Associated Migraine Headache
The purpose of this trial is to study the use of soy isoflavones in the prevention of menstrually-associated migraines. Additionally, this trial may provide insight into the menstrual cycle and menstrually-related headaches in…
- Trial name
- NCT00203255
- Testing
- Soy Isoflavones
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Thomas Jefferson University
Breast Cancer, Major Depressive Disorder
Wellbutrin XL, Major Depressive Disorder and Breast Cancer
To evaluate the efficacy of bupropion extended release (Wellbutrin XL™) in the treatment of Major Depressive Disorder in women with breast cancer.
- Trial name
- NCT00234195
- Testing
- bupropion extended release (Wellbutrin XL)
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Thomas Jefferson University
Preterm Birth
Does Fetal Fibronectin and Ultrasound Cervical Length Help in the Evaluation of Women With Suspected Preterm Labor?
The objective of this study is to investigate the effect of the use of both sonographic cervical length (CL) and fetal fibronectin (FFN) on the length of outpatient triage and preterm labor interventions in symptomatic women with…
- Trial name
- NCT00371046
- Testing
- Transvaginal ultrasound cervical length, Cervicovaginal fetal fibronectin
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Thomas Jefferson University