Clinical trials: sponsored by Tulane University
Trichomonas Vaginitis, Bacterial Vaginitis
Refining Treatment Options for Trichomonas Vaginalis Infection: A Comparative Analysis of Metronidazole and Secnidazole
This is a multi-centered, randomized, open-label, parallel, phase IV clinical trial comparing the effectiveness and cost-effectiveness of oral multi-dose metronidazole (MTZ) and oral single-dose secnidazole (SEC) for the…
- Trial name
- NCT06261840
- Testing
- Metronidazole 500 mg, Secnidazole 2000 MG
- Where
- 4 sites in United States
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Tulane University
Diabetes, Diabetes Mellitus
Continuous Glucose Monitoring (CGM) in an Underserved Population
The investigators aim is to conduct a randomized clinical trial in an underserved population who are either uninsured or on Medicaid and taking at least one injection of insulin daily.
- Conditions
- Diabetes, Diabetes Mellitus, Diabetes Type 2
- Trial name
- NCT07135531
- Testing
- Continuous Glucose Monitoring (CGM)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Tulane University
Chagas Disease
Short-course Benznidazole Treatment to Reduce Trypanosoma Cruzi Parasitic Load in Women of Reproductive Age
The investigators are proposing to perform a double-blinded, non-inferiority randomized controlled trial comparing a short 30-day treatment with BZN 150mg/day (30d/150mg) vs. a 60-day treatment with BZN 300 mg/day (60d/300mg).
- Trial name
- BETTY (NCT03672487)
- Testing
- Benznidazole
- Where
- 3 sites in United States, Argentina
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Tulane University School of Public Health and Tropical Medicine
Valvular Heart Disease, Pericardial Disease
PPG to Predict Ejection Fraction and Other Echographic Data in the General Population
The investigators are aiming to investigate the association between ejection fraction (EF) determined by echocardiography and signals obtained from Photoplethysmography (PPG) in the general population.
- Conditions
- Valvular Heart Disease, Pericardial Disease, Cardiomyopathies
- Trial name
- NCT04843371
- Testing
- Photoplethysmography
- Where
- 3 sites in United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Tulane University
Atrial Fibrillation, Stroke
Advanced Cardiac Imaging To Predict Embolic Stroke On Brain MRI: A Pilot Study
Demonstrating the pathophysiological link between Left Atrial (LA) and Left Atrial Appendage (LAA) pathology and embolic strokes in non-Atrial Fibrillation (AF) individuals represents a major advance in stroke prevention…
- Conditions
- Atrial Fibrillation, Stroke, Stroke, Cardiovascular, Vascular Cognitive Impairment
- Trial name
- NCT04769310
- Testing
- Cardiac and Brain MRI
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Tulane University
Covid19, Cardiovascular Complication
WEAICOR: Wearables to Investigate the Long Term Cardiovascular and Behavioral Impacts of COVID-19
This is an observational COVID-19 study that uses wearable health monitoring technology to follow COVID-19 positive individuals to monitor persistent symptoms and any potential long-term complications or cardiovascular and…
- Conditions
- Covid19, Cardiovascular Complication, Behavioral Changes
- Trial name
- WEAICOR (NCT04605965)
- Where
- 2 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Tulane University
Atrial Fibrillation
The CoAGulation Biomarkers and Atrial Fibrillation (COAG-AF) Pilot Study
The aim of the Correlation Of CoAGulation-Atrial Fibrillation (COAG-AF) study is to prove that an increase in pro-thrombotic biomarkers in AF is associated with an increase in AF burden.
- Trial name
- NCT04947657
- Where
- 3 sites in United States
- Volunteers
- 20 people
- Sponsor
- Tulane University
Atrial Fibrillation, Atrial Fibrillation Recurrent
Effect of Dronedarone on Atrial Fibrosis Progression and Atrial Fibrillation Recurrence
Patients who have undergone cardiac ablation will be randomized and blinded to one of two groups; one group will receive dronedarone while the other group will receive a placebo.
- Trial name
- EDORA (NCT04704050)
- Testing
- dronedarone 400 mg Oral Tablet
- Where
- 4 sites in United States
- Volunteers
- 22 people
- Sponsor
- Tulane University School of Medicine
Health Care Workforce Burn Out, Stress
LA-CEAL 4.0: Wearable Sensor Project
The study seeks to explore the efficacy of biofeedback collected via a wrist worn sensor in helping healthcare workers self-manage symptoms of stress and burnout.
- Trial name
- NCT06086028
- Testing
- Wrist worn sensor
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Tulane University
Human Immunodeficiency Virus, End Stage Renal Disease
Tulane Abdominal Transplant Institute (TATI) of Solid Organ Transplantation of HIV-Positive Recipients From HIV-Positive Donors
The U.S. Department of Health and Human Services (HHS), through the National Institutes of Health (NIH), published Final Human Immunodeficiency Virus (HIV) Organ Policy Equity (HOPE) Act Safeguards and Research Criteria for…
- Trial name
- NCT05159466
- Testing
- Kidney transplant
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Tulane University
Anxiety, Depression
M-O-M-S on the Bayou: Implementation of an Intervention for Mental Health in Pregnancy
Disasters have negative effects in the short term (physical trauma, adverse environmental exposures, and unstable housing) and the long term (relocation, changes in family functioning, and negative economic effects), which…
- Trial name
- NCT05838404
- Testing
- M-O-M-S on the Bayou
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Tulane University
Metastatic Castration-resistant Prostate Cancer
18F-fluciclovine PET in Metastatic Castration Resistant Prostate Cancer Treated With Life Prolonging Therapies
This is a pilot phase 2 single-arm study, of men with metastatic castration-resistant prostate cancer (mCRPC). Patients will be treated with any of the approved life-prolonging therapies: abiraterone 1000 mg daily plus prednisone…
- Trial name
- NCT04158245
- Testing
- 18F-fluciclovine PET Scan
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Tulane University
Hypertension, Health Behavior
Building Engagement Using Financial Incentives Trial - Hypertension
The goal of this pilot clinical trial is to determine feasibility and explore whether immediate versus delayed patient financial incentives improve patient engagement with self-monitoring of blood pressure in patients with…
- Conditions
- Hypertension, Health Behavior, Healthcare Patient Acceptance, Patient Engagement
- Trial name
- BENEFIT-H (NCT06195839)
- Testing
- Remote Patient Monitoring, Self-monitoring of hypertension-related factors, Immediate financial incentives
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Tulane University
Hypertension, Blood Pressure
Implementation of Multifaceted Patient-Centered Treatment Strategies for Intensive Blood Pressure Control (IMPACTS)
The IMPACTS study utilizes an effectiveness-implementation hybrid type 2 design to achieve two primary goals simultaneously: 1).
- Trial name
- IMPACTS (NCT03483662)
- Testing
- Multicomponent Intervention, Enhanced Usual Care
- Where
- 2 sites in United States
- Volunteers
- 1,272 people
- Sponsor
- Tulane University
Health Behavior, Colorectal Cancer
Building Engagement Using Financial Incentives Trial - Colorectal Cancer Screening
The goal of this pilot clinical trial is to determine feasibility and explore whether financial incentives paid to primary care patients for completing colorectal cancer screening increase completion of colorectal cancer…
- Conditions
- Health Behavior, Colorectal Cancer, Influenza, COVID-19
- Trial name
- BENEFIT-C (NCT06124131)
- Testing
- Financial incentive for colorectal cancer screening, Financial incentive for flu shot, Financial incentive for COVID-19 shot
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Tulane University
Gun Violence Prevention, Adolescent Behavior
Supportive Hospital-Based Intervention for Firearm Trauma
This study is a quasi-experimental design, specifically a non-randomized controlled trial (NCT) designed to test the effects of gun violence reduction intervention including MI for youth ages 16-24 years old who present to the…
- Trial name
- SHIFT (NCT06712940)
- Testing
- Motivational Interviewing and Firearm Safety Training, with Case Management
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- Tulane University
Hemophilia A
Factor IX as Adjunctive Therapy to Emicizumab (EMIX)
This trial will enroll patients with severe hemophilia A. Experiments will be run in vitro by spiking patients' blood with different molecules (currently used and theoretically proposed as adjunctive therapy to emicizumab)…
- Trial name
- NCT05281718
- Testing
- Factor IX
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- Tulane University
Parenting, Child Behavior
Longitudinal Follow-up of Brief Parenting Interventions to Reduce Risk of Child Physical Maltreatment
Universal and broad selective parenting education programs that improve parenting skills, increase parents' understanding of child development, and teach positive child discipline strategies can prevent use of corporal punishment…
- Conditions
- Parenting, Child Behavior, Child Rearing
- Trial name
- NCT04059185
- Testing
- Triple P-Level 2, Play Nicely, Usual care
- Where
- United States
- Volunteers
- 1,133 people
- Sponsor
- Tulane University
HIV, Mental Health
NOLA GEM: Feasibility and Acceptability of an MHealth Intervention for Violence-affected PLWH
The objective of the proposed research is to conduct formative work to develop, pilot and refine a smartphone delivered intervention for violence affected people living with HIV utilizing a novel spatial-temporal methodology…
- Conditions
- HIV, Mental Health, Substance Use
- Trial name
- NCT05784714
- Testing
- NOLA GEM
- Where
- 4 sites in United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Tulane University
Weight Loss
A Trial of the Ideal Protein System Versus Low Fat Diet for Weight Loss
This study will examine whether, compared to a standard, low-fat, calorie-restricted diet intervention, the clinic-supported Ideal Protein weight loss method will result in greater weight loss and improvement in cardiometabolic…
- Trial name
- RENEWAL (NCT03515889)
- Testing
- Ideal Protein Weight Loss Method, Standard Weight Loss
- Where
- United States
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Tulane University