Clinical trials: sponsored by Tulane University
Atherosclerosis, Cardiovascular Diseases
Bogalusa Heart Study
To determine the natural history of atherosclerosis, coronary artery disease, and hypertension in children and adults from birth through mid-life in a total biracial community.
- Conditions
- Atherosclerosis, Cardiovascular Diseases, Heart Diseases, Coronary Disease
- Trial name
- BHS (NCT00005129)
- Where
- United States
- Volunteers
- 11,737 people
- Sponsor
- Tulane University
Neonatal Abstinence Syndrome, Substance Withdrawal, Neonatal
The Effect of Music Therapy on Newborns
The clinical study is evaluating the impact of music therapy on neonates, specifically infants with neonatal opioid withdrawal syndrome (NOWS).
- Trial name
- NCT03987165
- Testing
- Music Therapy
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Tulane University
Psychopathology
Virtual Mom Power With High-Adversity Mothers and Children (MPHAMC)
This study is a randomized controlled confirmatory efficacy trial of virtual Mom Power (MP), a group-based, relationship-focused multifamily preventive intervention.
- Trial name
- NCT05129397
- Testing
- Mom Power, Mom Power Informational Mailing
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Tulane University
Malaria
Studies of a Candidate Aminoquinoline Antimalarial (AQ-13)
This is an initial efficacy study of a candidate antimalarial in human subjects with uncomplicated malaria caused by the most common and most important parasite in Africa (Plasmodium falciparum).
- Trial name
- NCT01614964
- Testing
- AQ-13 Treatment, Coartem Treatment
- Where
- Mali
- Volunteers
- 66 people
- Sponsor
- Tulane University
Atrial Fibrillation, Arrhythmia
Epigenetic Analysis of Regulation of the Inflammasome-activating NLRP3 Gene in Monocytes From Atrial Fibrillation Patients and Controls
The study will analyze blood from volunteers to determine whether there is an underlying epigenetic cause of the inflammation of the heart associated with atrial fibrillation (AF) and its progression with age.
- Trial name
- NCT04766814
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Tulane University
Ischemic Stroke
China Antihypertensive Trial in Acute Ischemic Stroke
This randomized trial tests the effect of early blood pressure reduction on major disability and death among patients with acute ischemic stroke in china.
- Trial name
- CATIS (NCT01840072)
- Testing
- Active antihypertensive treatment
- Where
- China
- Volunteers
- 4,071 people
- Sponsor
- Tulane University
Alcohol Abuse, Drug Use
The Weaving Healthy Families Program
Alcohol and other drug (AOD) abuse and violence in families are co-occurring risk factors that drive health disparities and mortality among Native Americans (NA), making the long-term goal of this research is to promote health…
- Conditions
- Alcohol Abuse, Drug Use, Violence, Domestic, Child Abuse
- Trial name
- NCT03924167
- Testing
- Weaving Healthy Families Program
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Tulane University
Covid19, Vaccine Refusal
Impact of LA-CEAL HALT COVID-19 Ambassador Program on Likelihood to Vaccinate
The purpose of the study is to assess the effectiveness of the HALT COVID Ambassador educational outreach program on increasing likelihood to vaccinate against COVID-19
- Trial name
- NCT04930965
- Testing
- Community health worker engagement
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Tulane University
Atrial Fibrillation, Fibrosis
Efficacy of Delayed Enhancement MRI-Guided Ablation vs Conventional Catheter Ablation of Atrial Fibrillation
This proposal is aiming at modifying and improving persistent AF management guidelines by evaluating targeting DE-MRI detected atrial fibrosis during AF ablation and its related effect on procedural outcome.
- Trial name
- DECAAFII (NCT02529319)
- Testing
- MRI-Guided Ablation, Conventional Ablation
- Where
- United States
- Volunteers
- 843 people, healthy volunteers welcome
- Sponsor
- Tulane University School of Medicine
Diabetes, Hypertension
Diabetes Complication Control in Community Clinics (D4C) Trial
The overall objective of the proposed cluster randomized trial is to test whether implementation of protocol-based integrated care will improve CVD risk factors (glycated hemoglobin [HbA1C], systolic blood pressure [SBP], and…
- Conditions
- Diabetes, Hypertension, Dyslipidemia, Cardiovascular Disease
- Trial name
- D4C (NCT02835287)
- Testing
- Protocol-based integrated care
- Where
- 2 sites in United States, China
- Volunteers
- 11,132 people
- Sponsor
- Tulane University
Hypertension
Text My Hypertension BP Meds NOLA
The specific aims of this research study are to 1. Engage participants with poorly controlled hypertension and medication non-adherence to use simple digital approaches, specifically recurring text-messages to improve medication…
- Trial name
- NCT05074173
- Testing
- Text
- Where
- 2 sites in United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Tulane University
Type 2 Diabetes, Hypertension
Effect of Renin-angiotensin-system Blockade on Urinary Free Light Chains in Patients With Type 2 Diabetes Mellitus
The purpose of this study is to study the effect of blocking the renin angiotensin system on urinary free light chain excretion as compared to urine microalbumin creatinine ratio in subjects with type 2 diabetes.
- Trial name
- UFLC (NCT02046395)
- Testing
- amlodipine, hydralazine, terazosin or hydrochlorothiazide
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Tulane University School of Medicine
Phenylketonuria, Behavior and Behavior Mechanisms
Evaluation of Behavior, Executive Function, Neurotransmitter Function and Genomic Expression Kuvan Nonresponders
This observational study seeks to establish evidence: 1. that physiologic changes, unrelated to effect on the Phenylalanine Hydroxylase (PAH) enzyme, occur in Phenylketonuria (PKU) patients who are treated with sapropterin…
- Conditions
- Phenylketonuria, Behavior and Behavior Mechanisms, PAH Gene Expression
- Trial name
- IST (NCT01274026)
- Testing
- sapropterin dihydrochloride
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Tulane University School of Medicine
Acute Ischemic Stroke
China Antihypertensive Trial in Acute Ischemic Stroke II
The investigators propose to conduct a multicenter randomized trial to test the primary hypothesis of whether early antihypertensive treatment starting between the first 24-48 hours after the onset of an acute ischemic stroke…
- Trial name
- CATIS-2 (NCT03479554)
- Testing
- Early antihypertensive treatment, Delayed antihypertensive treatment
- Where
- China
- Volunteers
- 4,810 people
- Sponsor
- Tulane University
Covid19
Estradiol and Progesterone in Hospitalized COVID-19 Patients
The purpose of this study is to determine to what extent a short systemic steroid therapy with estradiol and progesterone, administered early to hospitalized and confirmed COVID-19 positive patients of both sexes in addition to…
- Trial name
- NCT04865029
- Testing
- Estradiol Cypionate 5 mg/ml, Progesterone 200 mg Oral Capsule
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Tulane University
Obesity, Glucose Homeostasis
Bazedoxifene/Conjugated Estrogens (BZA/CE) Improvement of Metabolism (BIM)
The goal of this pilot clinical study is to perform a randomized placebo-controlled study to assess the beneficial effect of a 3 month-treatment with Bazedoxifene/Conjugated Estrogens (BZA/CE) vs.
- Conditions
- Obesity, Glucose Homeostasis, Postmenopausal Symptoms
- Trial name
- BIM (NCT02237079)
- Testing
- Bazedoxifene/Conjugated Estrogens (BZA/CE)
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Tulane University Health Sciences Center
Hypertension, Hypercholesterolemia
Clinical Trial of Protein and Blood Pressure
The purpose of this randomized, double-blind, controlled trial is to examine the effect of soybean protein supplementation on blood pressure in persons with prehypertension or stage-1 hypertension.
- Trial name
- ProBP (NCT00107744)
- Testing
- Soy protein-milk protein-carbohydrate, Milk protein-carbohydrate-soy protein, Carbohydrate-soy protein-milk protein
- Volunteers
- 352 people, healthy volunteers welcome
- Sponsor
- Tulane University
Prostatic Neoplasms, Prostatic Neoplasms, Castration-Resistant
68Ga-PSMA-11 Patients With Newly Diagnosed and Recurrent Prostate Cancer (Firefly)
This is a prospective, Phase 2, single-center, open-label study of 68Ga-PSMA-11 PET scans in patients with biochemically recurrent prostate cancer or those diagnosed and untreated with high risk or very high risk localized…
- Trial name
- Firefly (NCT04854369)
- Testing
- 68 Ga-PSMA-11 prepared using a PSMA-11 Sterile Cold Kit
- Where
- United States
- Sponsor
- Tulane University
Diabetes Mellitus, Type 2, Chronic Disease
Impact of CMS Reimbursement Policy Supporting Care Coordination in Louisiana
Investigators propose to use a natural experiment design to examine the impacts of the new CPT code (99490) for chronic care management on health outcomes.
- Trial name
- NCT03136471
- Where
- United States
- Volunteers
- 22,242 people, healthy volunteers welcome
- Sponsor
- Tulane University
Dermatomyositis, Adult Type
Evaluating Safety & Efficacy of Apremilast in the Treatment of Cutaneous Disease in Patients With Recalcitrant Dermatomyositis
With limited treatment options available for dermatomyositis, the investigators hypothesize that apremilast, a phosphodiesterase-4 (PDE-4) inhibitor, is a safe and efficacious add-on treatment in patients with refractory…
- Trial name
- NCT03529955
- Testing
- Apremilast 30mg
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Tulane University