Clinical trials: sponsored by Turku University Hospital
Jaw Deformity, Facial Asymmetry
Computational Modeling for Prediction of Acoustic Changes in Vowel Production Due to Orthognathic Surgery
A computational model of human sound production based on high quality anatomic measurements and physical laws of sound propagation cannot be accomplished without a comprehensive data set including both 3D-images of the speaker's…
- Trial name
- PUMA (NCT01887977)
- Testing
- MRI examination
- Where
- Finland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Chronic Neck Pain, Chronic Low Back Pain
Radiofrequency Denervation for Reducing Chronic Pain: a Meta-analysis
The meta-analysis of data obtained from randomized controlled trial on effectiveness of radiofrequency denervation on reducing chronic neck and low back pain.
- Trial name
- NCT01882959
- Testing
- Radiofrequncy Denervation
- Volunteers
- 374 people
- Sponsor
- Turku University Hospital
Diabetic Polyneuropathy, Postherpetic Neuralgia
Efficacy, Safety, Tolerability and Pharmacokinetics of Concomitant Administration of Tramadol With Duloxetine or Pregabalin
Tramadol is an opioid analgesic, which is widely used in the treatment of acute and neuropathic pain. Treatment of neuropathic pain often requires a combination of pain medications due to the complex nature of neuropathic pain…
- Trial name
- NCT01116531
- Testing
- Tramadol, Duloxetine, Pregabalin
- Where
- Finland
- Sponsor
- Turku University Hospital
Endometriosis
Operative Treatment of Endometriosis Patients in Turku University Hospital
The women's clinic at Turku University Hospital has also since year 2000 accomplished and systematically increased advanced surgical treatment for the endometriosis patients with difficult disease.
- Trial name
- ProEndo (NCT01849354)
- Where
- Finland
- Volunteers
- 600 people
- Sponsor
- Turku University Hospital
Quality of Life
The Quality of Life in Late Menopause
The purpose of this study is to evaluate the quality of life of late postmenopausal Finnish women and the factors affecting it.
- Trial name
- QoL (NCT01848223)
- Where
- Finland
- Volunteers
- 64 people
- Sponsor
- Turku University Hospital
Healthy
Effects of Voriconazole on the Pharmacokinetics and Pharmacodynamics of Oral Buprenorphine: A Two-phase Cross-over Study in Healthy Subjects
Variability in drug response can be due to either pharmacokinetic or pharmacodynamic factors. The reasons why people differ in pharmacokinetics or pharmacodynamics are manifold and include, e.g., genetic factors, diseases, age…
- Trial name
- NCT01466803
- Testing
- Vorikonazole
- Where
- Finland
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Sleep Apnea
Postmenopausal Women,Treatment of Sleep Apnea and Co-morbidities
The purposes of this study are to evaluate the degree and duration of medroxyprogesterone acetate effect as well as tolerability in postmenopausal women with nasal continuous positive airway pressure (CPAP) treated sleep apnea…
- Trial name
- NCT01472315
- Testing
- medroxyprogesterone acetate
- Where
- Finland
- Volunteers
- 34 people
- Sponsor
- Turku University Hospital
Stress Urinary Incontinence
Long-term Outcome of the TVT Procedure Without Preoperative Urodynamic Examination
A follow-up study of 191 patients operated on with the TVT procedure between January 1998 and May 2000 at the Department of Obstetrics and Gynecology in the Turku City Hospital.
- Trial name
- NCT01426048
- Testing
- Gynaecological examination and a supine stress test, questionnaires
- Where
- Finland
- Volunteers
- 138 people
- Sponsor
- Turku University Hospital
Stress Urinary Incontinence
The Outcome of the Transobturator Tape (TOT) Procedure
The aim of our study is to report the subjective and objective outcome of outside-in transobturator technique (TOT) (Monarc®) in long-term follow-up.
- Trial name
- NCT01532583
- Testing
- Gynaecological examination, a supine stress test, questionnaires
- Where
- Finland
- Volunteers
- 139 people
- Sponsor
- Turku University Hospital
Postoperative Pain
Pain Management After Forefoot Surgery
The purpose of this study was to compare the efficacy of transdermal fentanyl to placebo both administered together with peroral nonsteroidal antiinflammatory drug (NSAID) and paracetamol in treatment of postoperative pain after…
- Trial name
- NCT01666379
- Testing
- Fentanyl
- Where
- Finland
- Volunteers
- 60 people
- Sponsor
- Turku University Hospital
Atrial Fibrillation
Safety of Cardioversion of Acute Atrial Fibrillation
The purpose of this study is to investigate the complications of cardioversion of acute (<48 hours duration) atrial fibrillation (AF).
- Trial name
- FinCV (NCT01380574)
- Where
- 3 sites in Finland
- Volunteers
- 7,700 people
- Sponsor
- Turku University Hospital
IVF Treatment, Human Epididymal Secretory Protein E4
Serum Biomarker HE4 During IVF Treatment
Human epididymal secretory protein 4 (HE4) is a new biomarker for ovarian cancer. The effect of IVF stimulation will be evaluated in order to see whether severe hormonal changes in the gonadotrophin and steroid status affect the…
- Trial name
- FHE4 (NCT01576744)
- Where
- Finland
- Volunteers
- 20 people
- Sponsor
- Turku University Hospital
Healthy
Effect of Duloxetine and Venlafaxine on the Pharmacokinetics and Pharmacodynamics of Oral Tramadol: A Three-phase Randomized Balanced Cross-over Study in Healthy Volunteers
Tramadol is an opioid analgesic, which is widely used in the treatment of acute and neuropathic pain. After oral administration, tramadol is rapidly and almost completely absorbed.
- Trial name
- NCT01443520
- Testing
- Duloxetine, Venlafaxine
- Where
- Finland
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Intrahepatic Cholestasis, Pregnancy
Ursodeoxycholic Acid in the Treatment of Intrahepatic Cholestasis of Pregnancy
The purpose of this study is to examine the efficacy and safety of ursodeoxycholic acid (UDCA) in the treatment of patients with intrahepatic cholestasis of pregnancy (ICP).
- Trial name
- NCT01576458
- Testing
- ursodeoxycholic acid
- Where
- Finland
- Volunteers
- 20 people
- Sponsor
- Turku University Hospital
Mammary Ductal Carcinoma
The Significance of MRI in the Development of Diagnostics and Treatment of Breast Cancer
The purpose of this study is to determine how MRI changes the treatment and diagnostics of ductal breast cancer. 100 women with newly diagnosed breast cancer will participate the study.
- Trial name
- NCT01484704
- Where
- Finland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Deep Biliary Cannulation
The Use of Guide Wire in Biliary Cannulation: Angled or Straight Tipped Guide Wire?
The purpose of the study is to prospectively evaluate the deep biliary cannulation in ERCP with the angled tipped guide wire or the straight tipped guide wire.
- Trial name
- NCT01002404
- Testing
- angled and straight tipped guide wire
- Where
- Finland
- Volunteers
- 164 people
- Sponsor
- Turku University Hospital
Biliary Obstruction, Cholangitis
Treatment of Biliary Obstruction Using Biliary Stent With or Without Antireflux Valve
Biliary obstruction can be relieved by biliary stent. Ascending infection of biliary passage (cholangitis) causes hospitalization and obstruction of stents.
- Trial name
- NCT00990366
- Testing
- Cook´s biliary stent with an antireflux stent, normal biliary stent
- Where
- Finland
- Volunteers
- 15 people
- Sponsor
- Turku University Hospital
Healthy
Effect of Celecoxib and Etoricoxib on the Pharmacokinetics and Pharmacodynamics of Oral Tramadol
Tramadol is an opioid analgesic, which is widely used in the treatment of acute and neuropathic pain. After oral administration, tramadol is rapidly and almost completely absorbed.
- Trial name
- NCT01304069
- Testing
- Selecoxib, Etoricoxib
- Where
- Finland
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Shoulder Arthroscopy
Continuous Subacromial Bupivacaine
The investigators wanted to re-evaluate the effects of subacromial bupivacaine infusion after shoulder arthroscopy with standard surgical techniques, including rotator cuff operations.
- Trial name
- NCT01377415
- Testing
- bupivacaine
- Where
- Finland
- Volunteers
- 90 people
- Sponsor
- Turku University Hospital
Bone Tumors
Bioactive Glass Granules in Filling of Bone Defects
This is a randomized clinical trial that will be carried out to examine the use of bioactive glass granules (S53P4) as bone graft substitute in filling small and large bone defects as compared with autogenous and allogeneic bone…
- Trial name
- NCT01304121
- Testing
- Bioactive glass (SP53P4)
- Where
- Finland
- Volunteers
- 48 people
- Sponsor
- Turku University Hospital