Clinical trials: sponsored by Turku University Hospital
Pharmacokinetics and Pharmacodynamics of Sublingual Buprenorphine
Effects of Posaconazole and Voriconazole on the Pharmacokinetics and Pharmacodynamics of Sublingual Buprenorphine
Variability in drug response can be due to either pharmacokinetic or pharmacodynamic factors. The reasons why people differ in pharmacokinetics or pharmacodynamics are manifold and include, e.g., genetic factors, diseases, age…
- Trial name
- PosaBupre (NCT01367808)
- Testing
- vorikonazole, posakonazole
- Where
- Finland
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Type 2 Diabetes Mellitus, Healthy Volunteers
The Effects of Short-time High-intensity Interval Training on Tissue Glucose and Fat Metabolism in Healthy Subjects and Patients With Type 2 Diabetes
The objectives of this study are to investigate the effects of short-time high-intensity interval training on tissue glucose and fat metabolism in healthy lean subjects and type 2 diabetic patients using modern and noninvasive…
- Trial name
- HITPET (NCT01344928)
- Testing
- HIT exercise intervention, Aerobic exercise intervention
- Where
- Finland
- Volunteers
- healthy volunteers welcome
- Sponsor
- Turku University Hospital
Pharmacokinetics, Pharmacodynamics
Effect of Itraconazole and Ticlopidine on the Pharmacokinetics and Pharmacodynamics of Oral Tramadol
Tramadol is an opioid analgesic, which is widely used in the treatment of acute and neuropathic pain. After oral administration, tramadol is rapidly and almost completely absorbed.
- Trial name
- NCT01214941
- Testing
- Ticlopidine, Ticlopidine and itraconazole
- Where
- Finland
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
GERD
Conventional Nissen Fundoplication Versus Laparoscopic Nissen Fundoplication
This is a long-term follow-up of a prospective randomized trial comparing open and laparoscopic Nissen fundoplication.
- Trial name
- NCT01230944
- Testing
- Laparoscopic Nissen fundoplication, Open Nissen fundoplication
- Where
- Finland
- Volunteers
- 110 people
- Sponsor
- Turku University Hospital
Bone Substitutes
Bioactive Glass Composite Implants in Cranial Bone Reconstruction
The purpose of this study is to study composites of bioactive glass and methylmetacrylate with glass fibre reinforcement in cranial bone defect reconstruction.
- Trial name
- NCT01202838
- Testing
- Composite Implant
- Where
- Finland
- Volunteers
- 10 people
- Sponsor
- Turku University Hospital
Neuromuscular Blocking Agents
Effect of Nitrous Oxide on Cisatracurium Infusion Demands
Background: Recent studies have questioned our previous understanding on the effect of nitrous oxide on muscle relaxants, since nitrous oxide has been shown to potentiate the action of bolus doses of mivacurium, rocuronium and…
- Trial name
- NCT01152905
- Where
- Finland
- Volunteers
- 70 people
- Sponsor
- Turku University Hospital
Gut Microbiota, Skin Microbiota
Lactobacillus Rhamnosus GG: Interaction With Human Microbiota and Immunity
Hypothesis: Probiotics have been used as novel adjunct therapeutic approach in atopic dermatitis. In addition to balancing the gut microecology and promoting host immune defences, specific probiotics might further aid in…
- Conditions
- Gut Microbiota, Skin Microbiota, Humoral Immune Responses, Severity of Atopic Dermatitis
- Trial name
- NCT01148667
- Testing
- Casein hydrolysate added with LGG, Infants drink casein hydrolysate without LGG
- Where
- Finland
- Volunteers
- 40 people
- Sponsor
- Turku University Hospital