Clinical trials: sponsored by Turku University Hospital
Urinary Incontinence,Stress
Ultrasound and Cure Rate Three Months and 15 Years After TOT-procedure
The study is a cohort study. Between 2005 and 2008, a total of 54 patients were examined with ultrasound before and after TOT surgery. The collected data has not been previously published.
- Trial name
- NCT05787730
- Testing
- Transobturator tape
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Low Back Pain, Stress Fracture
Treatment of Spondylolysisin Pediatric Patients.
A clinical trial comparing healing of unilateral or bilateral spondylolysis in children treated with a Boston thoracolumbar orthosis (brace) or with a soft spinal brace (Porostrap lumbar support) for four months.
- Trial name
- NCT03675152
- Testing
- Soft spinal brace, thoracolumbar orthosis, Excersice restriction
- Where
- 2 sites in Finland
- Volunteers
- 60 people
- Sponsor
- Turku University Hospital
Myocardial Infarction, Myocardial Ischemia
SuperTROPO (Better Diagnostics of Myocardial Infarction With a Test for Special Forms of Troponin)
The aim of this study is to investigate whether measurement of the long forms of cTnT with the novel SuperTROPO assay would improve the diagnosis of myocardial infarction in patients in the emergency department.
- Trial name
- SuperTROPO (NCT05858112)
- Testing
- SuperTROPO novel assay to measure the long forms of cTnT
- Where
- Finland
- Volunteers
- 3,000 people
- Sponsor
- Turku University Hospital
VUR - Vesicoureteric Reflux
Diagnosing Vesicoureteric Reflux in Children by Direct Isotope Cystography and Contrast Enhanced Voiding Ultrasonography
The purpose of this study is to examine the applicability of contrast enhanced voiding ultrasonography in diagnosing vesicoureteral reflux (VUR) in pediatric patients compared to direct isotope cystography.
- Trial name
- NCT06138080
- Testing
- Contrast-enhanced voiding ultrasonography (CEVUS), Direct isotope cystography
- Where
- Finland
- Volunteers
- 100 people
- Sponsor
- Turku University Hospital
Infertility, Male
Modern Analyses of the Semen in Evaluating Male Fertility and Treatment Options of Male Infertility
Men are recruited to collect seminal plasma samples and serum samples from men with azoospermia, men receiving medical treatment of infertility and men attending semen analysis.
- Trial name
- SemiFluid (NCT02932865)
- Where
- Finland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Alzheimer Disease, Mild Cognitive Impairment
Brain Insulin Resistance in Mild Cognitive Impairment
Alzheimer´s disease (AD) is the most common cause of dementia. The most important risk factor for AD is old age; modifiable risk factors for AD include metabolic risk factors, i.e. diabetes, and obesity.
- Conditions
- Alzheimer Disease, Mild Cognitive Impairment, Positron Emission Tomography
- Trial name
- COINS (NCT06116188)
- Testing
- FDG-PET study
- Where
- Finland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Prostate Cancer, Prostate Hyperplasia
Prostate Metabolism, Cancer Risk and Gut Microbiota
This is a prospective, single center translational multiple cohort study to investigate the association of gut microbiota and prostate cancer.
- Trial name
- PROMIC (NCT06116851)
- Testing
- MRI scan and laboratory visit, Prostate biopsies, Radical prostatectomy and blood, urine and tissue sampling
- Where
- 2 sites in Finland
- Volunteers
- 300 people
- Sponsor
- Turku University Hospital
Male Infertility
Treatment of Severe Male Infertility - Predictive Factors (Imaging)
Testes of men with non-obstructive azoospermia (NOA) are imaged using MRI to find potential differences depending on the outcome, ie. sperm recovery in consequent microdissection testicular sperm extraction (MD-TESE).
- Trial name
- TESE-MRI (NCT02931721)
- Testing
- MRI
- Where
- 2 sites in Finland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Prostatic Hyperplasia, Prostate Cancer
Prostate Medication, Metabolism and Gut Microbiota
PROMED is a prospective, single center translational multiple cohort study to investigate the association of prostate medication and gut microbiota.
- Trial name
- PROMED (NCT06001619)
- Testing
- Prostate hyperplasia medication, LhRH-antagonist
- Where
- 2 sites in Finland
- Volunteers
- 100 people
- Sponsor
- Turku University Hospital
Diabetes Mellitus, Type 2
A Repeatability Study of Fatty Acid Uptake Using PET/MR Imaging in Patients With T2DM and Non-diabetic Control Subjects
The main purpose of this study is to evaluate the overall variation in the assessment of fatty acid uptake and blood flow in adipose tissue and skeletal muscle in the fasted and postprandial states by evaluating the repeatability…
- Trial name
- AM05 (NCT05132335)
- Testing
- Imaging Biomarkers
- Where
- 2 sites in Finland
- Volunteers
- 19 people
- Sponsor
- Turku University Hospital
Depression, Anxiety
Effectiveness of Enhanced Mental Health Support for Young People
The aim of the research project is to measure the effectiveness of an early and rapid psychiatric nurse intervention at schools in improving the emotional well-being and functioning of adolescents.
- Conditions
- Depression, Anxiety, Emotional Stress
- Trial name
- Nopsatuki (NCT05356949)
- Testing
- Intervention
- Where
- Finland
- Volunteers
- 124 people
- Sponsor
- Turku University Hospital
IBS - Irritable Bowel Syndrome, Microbial Substitution
The Optimal Route of Fecal Microbiota Transplantation for Irritable Bowel Syndrome
The object of this study is to find out is there an optimal route for the fecal microbiata transplant (FMT) in patients that suffer from irritable bowel syndrome.
- Trial name
- NCT05874830
- Testing
- Fecal microbiota transplant or plasebo through endoscopy
- Where
- 3 sites in Finland
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Acute Stroke
Effect of Music Listening on Stress in Acute Stroke
Investigation on changes in the neurochemical stress parameters in acute stroke. 30 patients are recruited in the stroke unit, blood samples are collected at fixed intervals during the first two days.
- Trial name
- MUKU3-1 (NCT05859841)
- Testing
- Music listening, Control
- Where
- Finland
- Volunteers
- 32 people
- Sponsor
- Turku University Hospital
Coronary Artery Disease
Total Body Perfusion in Patients With Chest Pain
The Purpose of this study is to better understand changes in obstructive coronary artery disease in different organs other than the heart such as the brain and the kidneys using a new generation total body PET scanner.
- Trial name
- KOVERI (NCT05825859)
- Where
- Finland
- Volunteers
- 300 people
- Sponsor
- Turku University Hospital
Bladder Cancer
Fluorescence Cystoscopy and Optimized MMC in Recurrent Bladder Cancer (FinnBladder 9)
Bladder cancer (BC), the second most common urological malignancy, is an important public health issue. One of the main challenges in the treatment of bladder cancer if the prevention of recurrences of non-invasive tumors, which…
- Trial name
- NCT01675219
- Testing
- white light TUR-BT, blue light TUR-BT, optimized MMC
- Where
- 10 sites in Finland
- Volunteers
- 400 people
- Sponsor
- Turku University Hospital
Pregnancy, Obesity
Nutrition and Pregnancy Intervention Study
A randomized double-blind placebo controlled intervention study with pregnant obese women (n=440) will be conducted. The intervention will involve consumption of fish oil and/or probiotic capsules from early pregnancy until 6…
- Conditions
- Pregnancy, Obesity, Gestational Diabetes Mellitus, Adiposity
- Trial name
- NCT01922791
- Where
- 2 sites in Finland
- Volunteers
- 439 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Early Skin-to-skin Contact, Psychological Distress
Effects of the Couplet Care in Neonatal Intensive Care Unit
This is a quasi-experimental before and after intervention study taking place in the level III NICU of Turku University Hospital in Finland to evaluate the effects of the Couplet Care, a care model which provides maternal and…
- Conditions
- Early Skin-to-skin Contact, Psychological Distress, Parenting, Preterm Infant
- Trial name
- NCT05655104
- Testing
- Couplet Care
- Volunteers
- 30 people
- Sponsor
- Turku University Hospital
Cancer
Exercise Intervention for Cancer Patients
Exhausting chemotherapy, adverse effects of chemotherapy and a lack of information on the benefits of physical exercise are the among the reasons for reduced physical exercise among cancer patients during chemotherapy courses.
- Trial name
- NCT04151238
- Testing
- Exercise intervention for cancer patients to increase physical activity during chemotherapy
- Where
- Finland
- Volunteers
- 8 people
- Sponsor
- Turku University Hospital
Ulcerative Colitis
Fecal Microbiota Transplantation and Newly Diagnosed Ulcerative Colitis (UC)
In this FinUC study we are trying to find out the efficacy and safety of the Fecal microbiota transplantation (FMT) in newly diagnosed active ulcerative colitis patients.
- Trial name
- FinUC (NCT04687150)
- Testing
- Fecal microbiota transplantation, Colored water
- Where
- Finland
- Volunteers
- 20 people
- Sponsor
- Turku University Hospital
Fracture of Tibia
Conservative Versus Intramedullary Nailing for Pediatric Tibial Shaft Fractures
Tibial shaft fracture is a common fracture in the pediatric and adolescent population. The outcomes of both conservative and operative treatment are not clear and to date there is no randomized prospective trial comparing…
- Trial name
- CINPED (NCT05501496)
- Testing
- intramedullary nailing, casting
- Where
- 2 sites in Finland
- Volunteers
- 66 people
- Sponsor
- Turku University Hospital