Clinical trials: sponsored by Umeå University
Traumatic Intracranial Hemorrhage, Brain Injuries
Mild Traumatic Brain Injury and the Risk for Traumatic Intracranial Hemorrhage
Management of traumatic brain injuries causes significant efforts on emergency departments (ED) and overall health care. Patients on antithrombotic treatment with even minor trauma to the head, although without significant…
- Trial name
- NCT05609721
- Testing
- no intervention, only observational study
- Where
- Sweden
- Volunteers
- 2,044 people
- Sponsor
- Umeå University
Traumatic Intracranial Hemorrhage, Traumatic Brain Injury
No Cases of Delayed Intracranial Hemorrhage (d-ICH) Among Patients With Mild Traumatic Brain Injury (mTBI) on Oral Anticoagulation Therapy
Abstract Purpose Patients with anticoagulation therapy has a higher risk of developing traumatic Intracranial Hemorrhage (tICH).
- Trial name
- NCT05609734
- Testing
- no intervention, only observational retrospective study
- Where
- Sweden
- Volunteers
- 249 people
- Sponsor
- Umeå University
Overweight and Obesity
Dietitian Online - Internet-based Dietetic Treatment Within Health Care Services
The project aims to investigate the effect of internet-based dietetic treatment (IDT) on patients, dietitians, and society. The project will show: If IDT is equivalent to traditional dietetic treatment with physical meetings…
- Trial name
- DiOn (NCT04245384)
- Testing
- Internet-based dietetic treatment with video calls, Traditional dietetic treatment
- Volunteers
- 400 people
- Sponsor
- Umeå University
Caries,Dental
Evaluation of Caries Prevention Based on Genetic Etiology and Risk.
Dental caries affects billions of people worldwide and involves saliva immunodeficiency, commensal pathogen and exposure (lifestyle) causal subtypes of the disease.
- Trial name
- PRECARIES (NCT05600517)
- Testing
- Fluoride
- Where
- Sweden
- Volunteers
- 520 people
- Sponsor
- Umeå University
Breast Cancer, Liver Metastases
BreCLIM-2 - A RCT Investigating Local Treatment for Breast Cancer Liver Metastases
Breast cancer is the second most common cancer in Sweden with an incidence of 8000 per year. The role of surgery for distant breast cancer metastasis beyond local lymph nodes remains controversial even though some reports suggest…
- Trial name
- BreCLIM-2 (NCT04079049)
- Testing
- Surgical intervention, Control
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Umeå University
Hydrocephalus, Normal Pressure
Using Cerebrospinal Fluid Dynamics to Optimize Treatment of Idiopathic Normal Pressure Hydrocephalus
The purpose of the study is to determine if the so called pulsatility curve, which describes the relationship between intracranial pressure (ICP) and ICP pulsatility, can be used to predict outcome of treatment, in the form of…
- Trial name
- PULSE-OPT (NCT03076723)
- Testing
- Change in shunt opening pressure, Simulated change in shunt opening pressure
- Where
- 5 sites in Finland, Sweden
- Volunteers
- 43 people
- Sponsor
- Umeå University
Accidental Falls
The Effectiveness of a Self-managed Digital Exercise Programme to Prevent Falls in Older Community-dwelling People
The overall aim of the study is to evaluate the effectiveness of a digital self-management exercise program in preventing falls in community dwelling older people.
- Trial name
- SafeStepRCT (NCT03963570)
- Testing
- Safe Step - digital exercise program, Control group
- Where
- Sweden
- Volunteers
- 1,628 people
- Sponsor
- Umeå University
Postoperative Complications
Sleeve Gastrectomy as a Standard Bariatric Procedure
This study compared differences in weight loss, comorbidity resolution and complications and reoperations between a recently established sleeve gastrectomy (SG) and prior laparoscopic Rox-en-Y gastric bypass (RYGB).
- Trial name
- NCT05336331
- Testing
- SG or a RYGB
- Where
- Sweden
- Volunteers
- 1,015 people
- Sponsor
- Umeå University
Female Stress Urinary Incontinence
Web-based Management of Female Stress Urinary Incontinence
The purpose of this study is to determine whether treatment of female stress urinary incontinence using a web-based programme is effective.
- Trial name
- NCT01032265
- Testing
- Web-based treatment with PFMT and elements of CBT, Pamphlet treatment
- Where
- Sweden
- Volunteers
- 250 people
- Sponsor
- Umeå University
Parenting, Children, Only
Digital Support for Parents of Children in Child Health Care
Becoming a parent is a life-changing event that can be both gratifying and stressful. As a parent, one is responsible for another person, where there sometimes is a need for new information, knowledge, and advice to live up to…
- Conditions
- Parenting, Children, Only, Health Care Seeking Behavior, Health Knowledge, Attitudes, Practice
- Trial name
- LValan (NCT05256407)
- Testing
- Intervention, digital support
- Where
- Sweden
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Umeå University
Idiopathic Normal Pressure Hydrocephalus (INPH), Brain Diseases
Ventriculomegaly and Gait Disturbance in the Senior Population in the Region of Västerbotten
Idiopathic normal pressure hydrocephalus (INPH) is a treatable disease of the elderly, typically causing gait impariment, dementia and urinary incontinence.
- Conditions
- Idiopathic Normal Pressure Hydrocephalus (INPH), Brain Diseases, Central Nervous System Diseases, Dementia
- Trial name
- VESPR (NCT05204745)
- Where
- Sweden
- Volunteers
- 6,500 people
- Sponsor
- Umeå University
Pancreas Cancer, Pancreas Neoplasm
Prognostic Factors in Periampullary Tumors and Cysts
The project aims at analysing prognostic and predictive factors involved in diagnostics and surgical treatment of cysts and tumors in the pancreas and periampullary region using both clinical data and blood and tissue samples for…
- Conditions
- Pancreas Cancer, Pancreas Neoplasm, Pancreas Cyst, Pancreatic Fistula
- Trial name
- NCT05155878
- Where
- Sweden
- Volunteers
- 500 people
- Sponsor
- Umeå University
Hypovolemia, Heart Failure
Prevalence of Hypovolemia and Heart Failure in Non-cardiac Surgery
Prevalence of biventricular function of the heart and preoperative level of venous return is not known in non-cardiac non-morbid obese population.
- Conditions
- Hypovolemia, Heart Failure, Diastolic Dysfunction, Systolic Dysfunction
- Trial name
- NCT03349593
- Testing
- Echocardiography
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Umeå University
Hemodynamic Instability, Anesthesia; Adverse Effect
Heart Failure and Hemodynamic Stability During Anesthesia Induction
The study aim is to investigate whether preoperative heart failure has impact on hemodynamic stability during anesthesia induction by target controlled infusion of anesthesia (TCI) in non-cardiac, non-morbidly obese surgery.
- Conditions
- Hemodynamic Instability, Anesthesia; Adverse Effect, Heart Failure, Diastolic Dysfunction
- Trial name
- NCT03576261
- Testing
- Preoperative colloid fluid bolus (Gelofusine), Preoperative transthoracic echocardiography
- Where
- Sweden
- Volunteers
- 44 people
- Sponsor
- Umeå University
Ethics Support
Ethics Communication in Groups Among Healthcare Professionals (The Ethics-com Study).
Moral distress has been described as a condition with frustration, guilt, anger and as one reason for health care professionals to leave the profession.
- Trial name
- Ethics-com (NCT05146102)
- Testing
- ethics communication in group, in line with "the one to five-step method"
- Where
- 2 sites in Sweden
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Umeå University
Stress, Health Knowledge, Attitudes, Practice
The PIFBO-study: Person-centred Information to Parents in Paediatric Oncology
The aim of this project is to evaluate a person-centred informational intervention aimed at parents of children with cancer. The following hypotheses will be tested: an informational intervention emanating from the parents'…
- Trial name
- PIFBO (NCT02332226)
- Testing
- Representational approach
- Where
- 2 sites in Sweden
- Volunteers
- 32 people
- Sponsor
- Umeå University
Cognitive Impairment
An Intervention Study to Reduce Drug-related Problems and Readmissions Among Old People With Dementia
The aim of this randomized controlled study is to investigate if medication reviews performed by a clinical pharmacist as part of a ward team can reduce drug related problems and reduce readmissions to hospital among elderly…
- Trial name
- NCT01504672
- Testing
- Medication review
- Where
- 2 sites in Sweden
- Volunteers
- 460 people
- Sponsor
- Umeå University
Mental Ill-health, Care Environment
The Light- and Environment Project in Psychiatric Inpatient Care
The care environment influences both patients' experiences of care as well as staff's experiences of the work environment. A radical change in physical environment is planned at a psychiatric ward, aiming at creating a care…
- Conditions
- Mental Ill-health, Care Environment, Light Installations
- Trial name
- LEPPIC (NCT03140618)
- Testing
- The light and environment project in psychiatric inpatient care
- Where
- Sweden
- Volunteers
- 24 people
- Sponsor
- Umeå University
Accidental Falls
Evaluation of Reach, Effects and Cost Effectiveness of a Fall Preventive Intervention Including a mHealth Application
The purpose is to evaluate reach, effects and costs effectiveness of a mobile, fall prevention exercise program for older community-dwelling persons (70+ years) in a pragmatic trial.
- Trial name
- NCT04161625
- Testing
- Digital exercise program with support
- Where
- Sweden
- Volunteers
- 173 people
- Sponsor
- Umeå University
Hormones, Cytokines
Effects of a Single Bout of Resistance Training Session on Hormonal Response in Pre-pubertal and Pubertal Boys
: Resistance training induces strength gains in both children and adolescents. Exercise training is linked to anabolic functions through the GH-IGF-I axis.
- Trial name
- NCT05022992
- Testing
- Resistance Training
- Where
- Sweden
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Umeå University