Clinical trials: sponsored by Umeå University
Parkinson Disease
Digital Dance for People With Parkinson's Disease During the COVID-19 Pandemic
Dance as a treatment to support physical, cognitive and emotional functioning, has gained increased acceptance as a healthcare intervention for people with Parkinson's Disease (PD).
- Trial name
- NCT04942392
- Testing
- Digital dance for PD
- Where
- Sweden
- Volunteers
- 33 people
- Sponsor
- Umeå University
Parkinson Disease, Cognitive Impairment
Cognitive Training in Parkinson's Disease, the iPARK Study
The aim of the iPARK-study is to investigate the effects of a process-based cognitive training program with focus on working memory in patients with Parkinson's Disease (PD).
- Trial name
- iPARK (NCT03680170)
- Testing
- Working memory updating training
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Umeå University
Dental Caries in Children
Prevention of Recurrent Caries With Lactobacilli PRECAL
The aim of this study was to compare the effect of drops containing probiotic bacteria (Lactobacillus reuteri 17938, Lactobacillus reuteri PTA 5289, Biogaia AB, Sweden) on the incidence of dental caries with placebo drops in…
- Trial name
- NCT04929340
- Testing
- Probiotic bacteria
- Where
- 3 sites in Sweden
- Volunteers
- 70 people
- Sponsor
- Umeå University
Vaccination; Infection, Covid19
Immune Response to Vaccination Against Covid-19, a Follow up Study
The study investigates the immune response after vaccination in individuals with and without pre-existing immunity to Coronavirus disease (COVID) -19. The participants are followed and sampled up to 4 years after vaccination.
- Trial name
- CoVacc (NCT04920357)
- Testing
- Vaccination
- Where
- 5 sites in Sweden
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Umeå University
Breast Neoplasm Female, Regional Anesthesia
PECS-2 for Breast Surgery
There is no consensus regarding which alternative is the best anesthesia for breast surgery, general anesthesia and morphine for postoperative analgesia or a combination of regional anesthesia and general anesthesia that possibly…
- Conditions
- Breast Neoplasm Female, Regional Anesthesia, Anesthesia, Regional Anesthesia Morbidity
- Trial name
- NCT03117894
- Testing
- Ropivacaine 5 mg/ml, 35 ml, Remifentanil 50 microg/ml, Betamethason 4 mg
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Umeå University
Dental Trauma
Cone-beam Computed Tomographic (CBCT) and Regenerative Endodontic Treatment.
Dental trauma injuries during childhood may have an adverse impact on oral health throughout life. If trauma injuries causes pulpal necrosis, then the root stop forming.
- Trial name
- Regeneration (NCT03544528)
- Testing
- Regeneration
- Where
- Sweden
- Volunteers
- 34 people
- Sponsor
- Umeå University
Abdominal Surgery, Continuous Positive Airway Pressure
Continuous Positive Airway Pressure After Abdominal Surgery
This is a randomized controlled trial with an allocation ratio of 1:1. Half the patients are randomized to continuous positive airway pressure (CPAP) and half to routine medical care.
- Conditions
- Abdominal Surgery, Continuous Positive Airway Pressure, Lung Function
- Trial name
- NCT04747535
- Testing
- Auto-CPAP, CPAP since before
- Where
- Sweden
- Volunteers
- 120 people
- Sponsor
- Umeå University
Eczema, Allergy
Probiotics in Prevention of Allergies, Obesity and Caries
During the period of 2000-2003, 179 healthy, term infants with no previous signs of allergic disease were recruited and randomized to daily intake of cereals with or without the addition of Lactobacillus paracasei subspecies…
- Conditions
- Eczema, Allergy, Asthma, Obesity
- Trial name
- ELEFANT (NCT00894816)
- Testing
- Lactobacillus F19
- Where
- Sweden
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Umeå University
Vaccination; Infection, Covid19
Risk of COVID-19 Infection After Vaccination
The purpose of this observational nationwide study is to evaluate the effects of three different COVID-19 vaccines for the outcome of different severities of incident COVID infection.
- Trial name
- NCT04848441
- Testing
- The COVID-19 vaccines BNT162b2, mRNA-1273 and ChAdOx1
- Volunteers
- 2,000,000 people
- Sponsor
- Umeå University
Type 2 Diabetes Mellitus, Mild Cognitive Impairment
DEMAND - Multifactorial Study to Reduce Dementia in People With Type 2 Diabetes
In the DEMAND pilot study, we will recruit and randomize 80 participants at two study sites (Umeå and Uppsala) for a one-year intervention.
- Trial name
- DEMAND (NCT03877783)
- Testing
- mediterranean diet, individualized fitness program, recommended modified pharmacological treatment
- Where
- Sweden
- Volunteers
- 10 people
- Sponsor
- Umeå University
Keratoconus
Treatment of Keratoconus With Advanced Corneal Crosslinking
The purpose of this study was to determine whether mechanical compression of the cornea during corneal crosslinking for keratoconus using a sutured rigid contact lens can improve the optical outcomes of the treatment.
- Trial name
- NCT02425150
- Testing
- Corneal reshaping/crosslinking (CRXL), Corneal Crosslinking (CXL)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Umeå University
Myopia, Corneal Crosslinking
Advanced Cross Linking for Low-grade Myopia
To evaluate the improvement in myopic refractive error and the corneal endothelial safety with a corneal crosslinking treatment regimen for mild myopia.
- Trial name
- PiXLO2 (NCT03197272)
- Testing
- PiXL
- Where
- Sweden
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Umeå University
Myopia, Corneal Crosslinking
Photorefractive Intrastromal Corneal Crosslinking as a Treatment for Low Grade Myopia
To assess the improvement in refractive error and the corneal endothelial safety with a customized corneal crosslinking treatment regimen for low grade myopia.
- Conditions
- Myopia, Corneal Crosslinking, Refractive Errors, Eye Diseases
- Trial name
- NCT03987880
- Testing
- 4.0 mm treatment, 3.5 mm treatment
- Where
- Sweden
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Umeå University
Infant
Effects of Milk Fat Globule Membrane (MFGM) - Enriched Formula With Reduced Energy and Protein Content on Growth and Development
Formula-fed infants differ from breast-fed infants in the growth pattern, risk for obesity and cardiovascular diseases, neurological development and morbidity in infections.
- Trial name
- TUMME (NCT00624689)
- Testing
- Modified formula (MFGM-enriched formula with reduced energy and protein content)
- Where
- Sweden
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Umeå University
Blood Gas Monitoring, Transcutaneous
Effect of PEP on Oxygen Saturation and Carbon Dioxide After Abdominal Surgery
Positive expiratory pressure( PEP) is routinely given to patients after surgery in order to improve lung function and oxygen saturation.
- Trial name
- NCT03176589
- Testing
- positive expiratory pressure (PEP), Deep breathing maneuvers
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Umeå University
Infant, Metabolism
Carbohydrate and Metabolism: a Pilot Study
The optimal choice of carbohydrate in infant formula needs to be assessed in more detail. Lactose has conventionally been used in most milk-based infant formulas, but more recently lactose-free formulas based on corn syrup…
- Trial name
- NCT02441296
- Testing
- Formula with lactose, Formula with maltodextrins
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Umeå University
Parastomal Hernia
Endostomal Three-dimensional Ultrasonography for Parastomal Hernia
The intention is to examine the role of ultrasonographic examination inside intestinal stomas in diagnosing parastomal hernia. Patients with a stoma since at least one year back who are being scheduled for abdominal surgery will…
- Trial name
- CTULOP (NCT04311333)
- Testing
- Endostomal three-dimensional ultrasonography, Computerized tomography of the abdomen, Clinical examination
- Where
- 3 sites in Sweden
- Volunteers
- 100 people
- Sponsor
- Umeå University
Nutrition Disorder, Infant
Effects of Two Different Parenteral Nutrition Regimes on Nutrient Intakes, Growth and Plasma Electrolytes in Very Low Birth Weight Infants
A single-center retrospective observational study comparing two cohorts of very low birth weight (VLBW, birth weight < 1500 grams) infants who received parenteral nutrition (PN) either before or after a concentrated PN regime was…
- Trial name
- PUMPA (NCT04085484)
- Testing
- More concentrated parenteral nutrition solution
- Where
- Sweden
- Volunteers
- 134 people
- Sponsor
- Umeå University
Type 2 Diabetes Mellitus
The Interaction Between Metformin and Microbiota - the MEMO Study.
Metformin has been used in Sweden since 1957, and it is recommended as first line therapy for type 2-diabetes (T2D) in national and international guidelines.
- Trial name
- MEMO (NCT03718715)
- Testing
- Metformin
- Where
- Sweden
- Volunteers
- 600 people
- Sponsor
- Umeå University
Aged
The Umeå High-Intensity Training Study
This randomized controlled trial will evaluate the effect of high-intensity training (HIT) in older sedentary people. Seventy older people, aged 65 and over, will be randomized to HIT or moderate-intensity continuous training…
- Trial name
- Umeå HIT (NCT03765385)
- Testing
- High-intensity training, Moderate-intensity continuous training
- Where
- Sweden
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Umeå University