Clinical trials: sponsored by Umeå University
Milk Allergy
Swedish Study of Immunotherapy for Milk Allergy in Children
This trial is a two-armed open randomized controlled trial in children aged 5-15 years with challenge proven Immunoglobulin E (IgE)-associated milk allergy.The purpose is to determine if oral immunotherapy with milk can induce…
- Trial name
- SWITCH (NCT03819556)
- Testing
- Milk protein in fresh milk
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Umeå University
Osteoarthritis, Hip, Arthroplasty Complications
A Randomized RSA Study Comparing HXLPE to Conventional Polyethylene in Cemented Total Hip Arthroplasty
A prospective randomized study comparing two types of cemented acetabular components, a highly-crosslinked polyethylene or conventional polyethylene in total hip arthroplasty.
- Trial name
- NCT04322799
- Testing
- Device: Randomization between prosthetic components
- Where
- Sweden
- Volunteers
- 57 people
- Sponsor
- Umeå University
Anemia, Iron-Deficiency
Iron Supplementation of Marginally Low Birth Weight Infants
Iron is essential for brain development and there is a well established association between iron deficiency in infants and poor neurological development. In Sweden, about 5% of newborns have low birth weight (< 2500 g).
- Conditions
- Anemia, Iron-Deficiency, Child Behavior Disorders, Cognitive Manifestations
- Trial name
- JOHN (NCT00558454)
- Testing
- Iron
- Where
- 2 sites in Sweden
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- Umeå University
Infant, Dietary Supplements
Iron Absorption From Infant Formula and Iron Drops in Infants (MJAU-studien)
Iron deficiency (ID) affects up to 25% of Swedish infants and severe ID is associated with cognitive and behavioral problems. To avoid this, iron supplements or iron-fortified infant foods are recommended for infants.
- Conditions
- Infant, Dietary Supplements, Food, Fortified
- Trial name
- MJAU (NCT01216709)
- Testing
- ferrous sulfate, iron-fortified infant formula (12.4 mg iron/L), iron-fortified infant formula (2.3 mg iron/L)
- Where
- Sweden
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Umeå University
Postoperative Pain
Postoperative Pain After Colorectal Surgery
This study aimed to evaluate pain after elective colorectal surgery and to identify risk factors for postoperative pain. Patients:All elective colorectal surgeries at the department of surgery, Umeå university Hospital, Umeå…
- Trial name
- NCT04318860
- Where
- Sweden
- Volunteers
- 459 people
- Sponsor
- Umeå University
Stroke, Dysphagia
Oral Neuromuscular Training in Stroke Patients With Dysphagia
This study aims to explore if oral neuromuscular training is superior to orofacial sensory-vibration stimulation in patients with oropharyngeal dysphagia.
- Trial name
- NCT04164420
- Testing
- Oral neuromuscular training and orofacial sensory-vibration, Orofacial sensory-vibration stimulation
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Umeå University
Hernia, Inguinal, Hernia, Femoral
Chronic Pain After Groin Hernia Surgery in Women
The goal of this study was to evaluate chronic pain and reoperation rates due to recurrence after groin hernia surgery in women compared to men and surgical method.
- Trial name
- NCT04228536
- Testing
- Totally ExtraPeritoneal (TEP) repair, TransAbdominal PrePeritoneal (TAPP) repair, Open anterior mesh repair (OAM)
- Volunteers
- 44,915 people
- Sponsor
- Umeå University
Participation, Patient, Psychiatric Hospitalization
Shared Decision Making in Psychiatric Inpatient Care
Introduction National guidelines and The Patient Act from 2014 call for an active role for the patient in the decision making process.
- Conditions
- Participation, Patient, Psychiatric Hospitalization, Psychosis
- Trial name
- DEAL (NCT04175366)
- Testing
- Shared Decision Making
- Where
- 2 sites in Sweden
- Volunteers
- 160 people
- Sponsor
- Umeå University
Challenging Behaviour
Effects of a Web-based Training Programme Focusing on Challenging Behaviour
The interaction between people with intellectual disabilities and professional carers is often influenced by communicative difficulties contributing challenging behaviours.
- Trial name
- NCT03390868
- Testing
- Web-based training for staff
- Where
- Sweden
- Volunteers
- 212 people
- Sponsor
- Umeå University
Healthy, Exposure to Pollution
Sympathetic Nerve Response Incited by Biodiesel Exhaust Exposure
The adverse effects of current ambient air pollution on cardiovascular and respiratory health have been demonstrated in an extensive series of epidemiological, observational and experimental studies.
- Trial name
- NCT03698344
- Testing
- Biodiesel exhaust exposure
- Where
- Sweden
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Umeå University
Healthy
Acute Vascular Effects of E-cigarette Use
Tobacco use harms nearly every organ in the body and has been linked to ischemic heart disease, chronic obstructive pulmonary disease, stroke, respiratory illness, lung cancer and other cancers.
- Trial name
- NCT03746119
- Testing
- E-cigarette vapor containing nicotine, E-cigarette vapor, nicotine free
- Where
- Sweden
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Umeå University
Anastomotic Leak
Anastomotic Leakage After Anterior Resection for Rectal Cancer - Predictive Biomarkers and Rectal Blood Flow
The purpose of this study is to determine whether reduced rectal blood flow is associated with the extent of surgery when performing an operation to remove rectal cancer.
- Trial name
- NCT02401100
- Where
- Sweden
- Volunteers
- 36 people
- Sponsor
- Umeå University
Hemodynamic Instability, Fluid Therapy
Hemodynamic Stability During Induction of Anaesthesia
The study aim is to investigate if preoperative volume bolus based on lean body weight could preserve mean arterial pressure during target controlled infusion of anaesthesia (TCI) or rapid sequence induction of anaesthesia (RSI)…
- Conditions
- Hemodynamic Instability, Fluid Therapy, Anesthesia; Adverse Effect
- Trial name
- NCT03394833
- Testing
- gelofusine
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Umeå University
Adverse Effect, Anesthesia
Airway Management During TCI vs RSI Anesthesia Induction
The aims of this observational study is to evaluate and compare feasibility of airway management during standardized TCI and RSI anesthesia induction.
- Conditions
- Adverse Effect, Anesthesia, Airway Complication of Anesthesia
- Trial name
- NCT03723109
- Testing
- Induction of anesthesia
- Where
- Sweden
- Volunteers
- 70 people
- Sponsor
- Umeå University
Rectal Cancer
Radiographic Validation of the Inferior Mesenteric Artery Tie Level in Rectal Cancer Surgery
The inferior mesenteric artery is the feeding vessel for tumours in the rectum. When performing surgery for these tumours, the surgeon can cut the vessel close to the aorta or after the vessel bifurcates to the superior rectal…
- Trial name
- RAVAL (NCT03875612)
- Where
- 2 sites in Sweden
- Volunteers
- 98 people
- Sponsor
- Umeå University
Insulin Resistance, Hypertension
Metabolic and Cardiovascular Effects of Renal Denervation
Renal denervation has recently shown to improve glucose metabolism and insulin sensitivity in addition to reducing blood pressure. The mechanisms are however unclear.
- Trial name
- NCT02057224
- Testing
- Renal denervation using Medtronic Symplicity System (mono-electrode)
- Where
- Sweden
- Volunteers
- 5 people
- Sponsor
- Umeå University
Pulmonary Disease, Chronic Obstructive
Feasibility and Effects of KOL-webben in Patients With COPD
This study evaluates the effects of KOL-webben (the COPD web), an interactive web-based system directed towards two target groups; people with chronic obstructive pulmonary disease (COPD) and health professionals in primary care.
- Trial name
- NCT02696187
- Testing
- KOLwebben
- Where
- Sweden
- Volunteers
- 83 people
- Sponsor
- Umeå University
Cushing Syndrome, Hypercortisolism
Liquorice and Salivary Cortisol
Salivary cortisol is used as a diagnostic analysis in the investigation of suspected Cushings' syndrome. This study evaluates if liqourice intake increases salivary cortisol in healthy individuals.
- Trial name
- NCT04045015
- Testing
- Liqourice
- Where
- Sweden
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Umeå University
Glaucoma
Blood Flow of Ophthalmic Artery and Glaucoma
The main purpose of this project is to investigate the blood flow of the ophthalmic artery (OA) in patients with ocular hypertension, high tension glaucoma and normal tension glaucoma.
- Trial name
- NCT02656979
- Testing
- Latanoprost
- Where
- Sweden
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Umeå University
Childhood Obesity
Group Sessions and Web-based Treatment Targeting Children With Obesity Age 5-12 Years and Their Families
The aim of this study is to assess the efficacy of group sessions and a web-based program for children with obesity age 5-12 years and their parents.
- Trial name
- Webcop (NCT04013230)
- Testing
- Usual care, Web-COP
- Where
- 3 sites in Sweden
- Volunteers
- 60 people
- Sponsor
- Umeå University