Clinical trials: sponsored by Unity Health Toronto
Obesity
Effects of Viscous Fibre Containing Foods on Satiety (Gel Form)
The purpose of this study is to assess whether low caloric, low energy density, konjac food products are effective in appetite regulation when administered as caloric replacements.
- Trial name
- NCT02134938
- Testing
- Konjac Glucomannan
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Arterial Stiffness, Blood Pressure
Korean Red Ginseng Rg3 Extract on Arterial Stiffness and Blood Pressure
The purpose of the study is to evaluate the acute effect of a standardized extract of KRG (Rg3-KRG) consisting of 30% total ginsenosides, including 10% Rg3 ginsenoside on arterial stiffness and blood pressure, as measured by the…
- Trial name
- KRAB (NCT01951443)
- Testing
- Ginseng, Wheat Bran
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Type 2 Diabetes, Metabolic Syndrome
Acute Dose Response of Korean White Ginseng in Metabolic Syndrome or Type 2 Diabetes
The study is a Phase-I like double blind randomized placebo controlled crossover design trial. The objective is to assess the dose response relationship on glycemic and vascular effects of an acutely administered Korean White…
- Trial name
- KWG (NCT01699074)
- Testing
- 1 gram of White Korean Ginseng, 3 grams of White Korean Ginseng, 6 grams of White Korean Ginseng
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Unity Health Toronto
Healthy
Acute Effect of Nitrate From Natural Dietary Sources on Arterial Stiffness and Blood Pressures in Healthy Individuals
The purpose of this study is to evaluate the acute effect of a meal high in dietary nitrates on aortic augmentation index, brachial and aortic blood pressures, and subendocardial viability ration (SEVR).
- Trial name
- DNAB (NCT01604993)
- Testing
- Spinach soup, Asparagus soup
- Where
- Canada
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Cardiovascular Diseases
Effect of Flax, Poppy, Sesame & Salba on Postprandial Blood Glucose Response, Vascular, Appetite & Sensory Parameters
Consumption of whole grains has been heavily endorsed by both government and major health agencies, as evidenced in Health Canada's Food Guide, the US Department of Agriculture's Food Pyramid, and the Heart and Stroke…
- Trial name
- NCT01579656
- Testing
- Salba, Poppy, Flaxseed
- Where
- Canada
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Healthy
Effects of Mode of Administration of Soluble Fibre Blend on Glycemia, Appetite & Sensory Parameters
Soluble, viscous fibre has been established as an effective dietary component for lowering postprandial glycemia and promoting satiety.
- Trial name
- FI-FORM (NCT01657058)
- Testing
- Soluble viscous fibre blend powder in hydrophobic matrix, Soluble viscous fibre blend in pre hydrated form, No soluble viscous fibre blend
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Chronic Postoperative Pain, Headache
Effects of Perioperative Pregabalin for Post-Craniotomy Pain
Objective: To compare the incidence of chronic pain at 3 months among adults undergoing craniotomy between those received two different doses of pregabalin and those receiving placebo.
- Trial name
- NCT01591980
- Testing
- Pregabalin
- Where
- Canada
- Sponsor
- Unity Health Toronto
Diabetes, Healthy
Soluble Fibre Enriched CHO Food Study
The proposed study will examine the effects of incorporating a soluble fibre blend into commonly consumed refined carbohydrate foods on sensory parameters and postprandial blood glucose.
- Trial name
- NCT01898026
- Testing
- Bread, Mashed Potatoes, Muffins
- Where
- Canada
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Acute Disease
A Virtual Ward to Reduce Readmissions After Hospital Discharge
The purpose of this study is to see whether a Virtual Ward reduces readmissions after hospital discharge.
- Trial name
- NCT01108172
- Testing
- Virtual Ward, Usual care
- Where
- 5 sites in Canada
- Volunteers
- 1,928 people
- Sponsor
- Unity Health Toronto
Diabetic Macular Edema
Efficacy and Safety Study to Evaluate Two Doses of Oral DMI-5207 in Adult Subjects With Diabetic Macular Edema
The drug being tested in this study is low doses of Optina (formerly known as Danazol) (DMI-5207) that may be an effective treatment for diabetic retinopathy and diabetic macular edema (DME).
- Trial name
- NCT02002403
- Testing
- Danazol
- Volunteers
- 34 people
- Sponsor
- Unity Health Toronto
Breast Cancer, Psychosocial Effects of Cancer and Its Treatment
Stress Reduction in Older Women With Stage II, Stage III, or Stage IV Breast Cancer
RATIONALE: Transcendental meditation may be an effective way to decrease the amount of stress in older women with breast cancer.
- Trial name
- NCT00006346
- Testing
- psychosocial assessment and care, quality-of-life assessment
- Where
- 3 sites in United States
- Sponsor
- Unity Health Toronto
Healthy
Acute Vascular Response To Meals Varying In Glycemic Index And Glycemic Load
This study examines the effects of carbohydrate type (high- or low-Glycemic Index (GI)) and amount (high- or low-Glycemic Load (GL)) have on blood glucose levels, blood pressure and arterial stiffness in healthy individuals.
- Trial name
- HILO (NCT01883700)
- Testing
- Boiled Pasta, Boiled Chickpeas with Oil, Instant Mashed Potatoes
- Where
- Canada
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Homeless Persons, Emergency Medical Services
Attitudes of Medical Trainees Towards Homeless Persons Presenting for Care in the Emergency Department
Homelessness is a significant problem in Canada, and many homeless people will seek routine care in the Emergency Department (ED) as a result of barriers to access.
- Trial name
- NCT00281398
- Testing
- Questionnaire
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Obesity
Satiety Study of a Carbohydrate Meal to a Highly Viscous Gel Meal
To evaluate the effects of Konjac on satiety and subsequent food intake in healthy individuals.
- Trial name
- InGel (NCT01875627)
- Testing
- Konjac noodles, Carbohydrate and Konjac Noodles, Carbohydrate noodles
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Impaired Glucose Tolerance, Diabetes
Effect of Ginseng on Glycemic Control
Ginseng (American ginseng, Asian ginseng, Korean ginseng etc) is expected to show positive hypoglycemic effects, including improvements in glycated blood proteins[HbA1c], fasting glucose, fasting insulin, and the homeostasis…
- Trial name
- NCT01841229
- Where
- Canada
- Volunteers
- 770 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Coronary Angioplasty, Coronary Artery Disease
Arterial Closure vs Direct Compression for Hemostasis After PCI - The ACDC Trial
Hemostasis at the arterial puncture site after percutaneous coronary interventions is achieved by either placement of a puncture closure device or by delaying sheath removal for hours to allow normalization of heparin induced…
- Trial name
- NCT00264264
- Testing
- Closure Device, Direct Compression
- Where
- Canada
- Volunteers
- 572 people
- Sponsor
- Unity Health Toronto
Chronic Kidney Disease
Intensive Dietary Education to Lower Serum Phosphorus in Patients With Chronic Kidney Disease
A low phosphorus diet is recommended for patients with chronic kidney disease who exhibit high levels of phosphorus. The purpose of this study is to determine the effects of a more intensive, innovative dietary phosphorus…
- Trial name
- NCT00656279
- Testing
- Intensive dietary phosphorus education
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Unity Health Toronto
Critical Care Trial Participation Consent by SDM
The Approach Study
In the Approach Study, the investigators will study the 'process' by which Substitute Decision Makers (SDMs) are approached for consent for their loved one's participation in critical care research.
- Trial name
- NCT01232621
- Testing
- Physician Introduction of research personnel
- Where
- Canada
- Volunteers
- 138 people
- Sponsor
- Unity Health Toronto
Heart Failure
The Prevalence of Thiamin Deficiency in Ambulatory Patients With Heart Failure
Patients with heart failure are at an increased risk for thiamin deficiency (TD), for many reasons such as malnutrition and the use of diuretic drugs.
- Trial name
- NCT00953823
- Where
- Canada
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Education, General Surgery
Individualized Deliberate Practice on a Virtual Reality Simulator
Training on simulated models in a surgical skills laboratory has been shown to improve technical performance in the operating room.
- Trial name
- NCT01753947
- Testing
- Deliberate Practice
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto