Clinical trials: completed, sponsored by Unity Health Toronto
Hysterectomy for Abnormal Uterine Bleeding
Laparoscopic Gynecology Curriculum for Residents
Gynecologists are currently using laparoscopy to perform many surgeries traditionally approached by laparotomy. The technical skills required for laparoscopic surgery are different than the skills required for laparotomy, causing…
- Trial name
- NCT01916343
- Testing
- Study Laparoscopic Curriculum
- Where
- Canada
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Postpartum Depression
Postpartum Anemia and Postpartum Depression
Postpartum anemia (PPA) and Postpartum depression (PPD) are common afflictions affecting women after childbirth. Both disorders have a significant impact on women's health and functional status.
- Trial name
- PPADS (NCT00782912)
- Where
- Canada
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
HIV, AIDS Virus
HIV Testing in Pregnant Women: Evaluating an Opt-Out Testing Strategy
Mother-to-child transmission of HIV is an important but preventable mode of infection. Prevention depends on identifying pregnant women infected with HIV and offering medications during pregnancy which can dramatically decrease…
- Conditions
- HIV, AIDS Virus, Pregnancy
- Trial name
- NCT00393302
- Testing
- HIV screening in pregnancy
- Where
- Canada
- Volunteers
- 1,074 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Rubella, Vaccine
Rubella Susceptibility in Multiparous Women
The purpose of this study is to determine the reasons why multiparous women (women who are pregnant and have been pregnant before) might still be susceptible to rubella.
- Trial name
- NCT00401505
- Where
- Canada
- Volunteers
- 310 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Pregnancy
Text Message Reminders for Influenza Vaccine in Pregnancy
Influenza virus accounts for numerous cases (epidemics) of respiratory illnesses each year worldwide and affects people of all ages.
- Trial name
- NCT02428738
- Where
- Canada
- Volunteers
- 317 people
- Sponsor
- Unity Health Toronto
BACTERIAL VAGINOSIS
Bacterial Vaginosis Screening at IUD Insertion
A number of studies have shown a higher prevalence of BV among IUD users.13,,14 None, however, have screened women prior to inserting the IUD.
- Trial name
- NCT00802386
- Where
- Canada
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Laparoscopic Hysterectomy for Benign Conditions
Comparing Two Devices of Uterine Manipulation and Vaginal Fornix Delineation at Total Laparoscopic Hysterectomy
We hypothesize, that the use of the Hohl manipulator® at total laparoscopic hysterectomy reduces operative time (from skin incision to detachment of the uterus) and lateral termal damage of the vaginal wall during colpotomy due…
- Trial name
- NCT02197728
- Testing
- Use of the Colpo-Probe™ Vaginal Fornix Delineator or Hohl manipulator® during total laparoscopic hysterectomy
- Where
- Canada
- Volunteers
- 91 people
- Sponsor
- Unity Health Toronto
Cystocele
Lower Urinary Tract Symptoms Screening Questionnaire
The purpose of this study is to determine the validity of a screening tool which has been designed to detect the presence or absence of lower urinary tract symptoms in the general female population.
- Trial name
- LUTS-2 (NCT01616810)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
HPV
Human Papilloma Virus (HPV) Knowledge and Attitudes and the Role of (SES) Socioeconomic Status and Ethnicity
This is a survey study to assess the vaccination knowledge and attitudes of women in an inner city Gynecology clinic. Results of this study will help determine which factors influence vaccination knowledge and attitudes.
- Trial name
- NCT01105000
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Gonococcal Infection, Chlamydia Infections
Screening of Gonococcal and Chlamydial Infections in the Third Trimester
Untreated maternal infection with gonorrhea and/or chlamydia can have serious complications in pregnancy and the neonatal period.
- Trial name
- NCT03073538
- Volunteers
- 1,691 people
- Sponsor
- Unity Health Toronto
Chronic Rhinosinusitis
A Randomized Controlled Trial Evaluating Postoperative Debridement Following Endoscopic Sinus Surgery
Chronic rhinosinusitis (CRS) is a common sinus and nasal condition affecting more than 33 million Americans. The treatment of CRS typically begins with maximal medical therapy however, when this fails to improve patient symptoms…
- Trial name
- NCT02154555
- Testing
- debridement
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Unity Health Toronto
Diabetes Mellitus Type 2, Hypertension
Combined Rg3-enriched Korean Red Ginseng and American Ginseng in the Management of Hypertension in Type 2 Diabetes
The study is a combined Phase-I like (safety) and Phase-II like (efficacy) double blind randomized placebo controlled trial. The objective is to investigate whether the combination of AG and Rg3-enriched Korean Red ginseng added…
- Trial name
- R-KAT (NCT01578837)
- Testing
- Ginseng, Wheat Bran
- Where
- 2 sites in Canada, Croatia
- Volunteers
- 90 people
- Sponsor
- Unity Health Toronto
Type2 Diabetes, Coronary Heart Disease
Konjac-Mannan Improves Glycemia and Other Risk Factors for CHD in T2DM
To examine whether Konjac-mannan fiber improves metabolic control measured by glycemia, lipidemia, and blood pressure in individuals with type-2 diabetes.
- Trial name
- NCT03741660
- Testing
- konjac glucomannan, wheat bran
- Volunteers
- 11 people
- Sponsor
- Unity Health Toronto
Insulin Resistance Syndrome
Effect of Konjac-mannan in Individuals With Insulin-Resistance Syndrome
To study whether a diet high in fiber from Konjac-mannan (KJM) has an effect on metabolic control in individuals with insulin resistance syndrome.
- Trial name
- NCT03741686
- Testing
- konjac glucomannan, wheat bran
- Volunteers
- 11 people
- Sponsor
- Unity Health Toronto
Lipidemia, Healthy
Viscosity of Fibre Predicts Cholesterol-lowering in Healthy Individuals
To investigate the role of fibre viscosity (low, medium, high) in lowering cholesterol in healthy individuals
- Trial name
- NCT03741621
- Testing
- Viscous Fibre Blend, Psyllium, Wheat Bran
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Colorectal Cancer
A Randomized Control Trial of a Simulation-based Curriculum to Enhance Skills in Colonoscopy
Colonoscopy is a commonly used medical procedure. Medical and surgical residents learning colonoscopy typically learn the procedure experientially but simulation based teaching is increasingly being integrated into training…
- Trial name
- NCT01991522
- Testing
- Curriculum Group, Self-directed learning group
- Where
- Canada
- Volunteers
- 33 people
- Sponsor
- Unity Health Toronto
Type 2 Diabetes, Obesity
Canola-Mediterranean Diet Study in T2DM
The purpose of the study is to assess whether a Mediterranean-type weight-loss diet, enriched with canola oil, high in plant protein, and low in carbohydrates will produce blood sugar control, reduce coronary heart disease (CHD)…
- Conditions
- Type 2 Diabetes, Obesity, Overweight, Cardiovascular Diseases
- Trial name
- NCT02245399
- Testing
- A canola oil enriched mediterranean diet, A high wheat fiber diet
- Where
- 3 sites in Canada
- Volunteers
- 164 people
- Sponsor
- Unity Health Toronto
Aortic Aneurysm, Thoracic
The Aortic Surgery Cerebral Protection Evaluation (ACE) Randomized CardioLink-3 Trial
The ACE trial is a multicentre, randomized controlled trial comparing axillary vs. innominate artery cannulation for established antegrade cerebral perfusion in patients having aortic surgery (thoracic and aortic arch) requiring…
- Trial name
- NCT02554032
- Testing
- Axillary artery cannulation, Innominate artery cannulation
- Where
- 2 sites in Canada
- Volunteers
- 110 people
- Sponsor
- Unity Health Toronto
Dysphonia, Singing
Effects of External Vibration on Voice Quality in Muscle Tension Dysphonia Patients and Classically Trained Singers
Muscle tension dysphonia (MTD) is a disabling voice disorder which causes severe voice change, neck pain, and voice fatigue. Current therapy modalities to treat these disorders include multiple visits to a qualified speech…
- Trial name
- NCT02083341
- Testing
- Lelo® Siri vibrator, Lelo® Siri vibrator with vibration component removed
- Where
- Canada
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Disorder; Heart, Functional, Postoperative, Cardiac Surgery
Transfusion Requirements in Cardiac Surgery III
TRICS-III is an international, multi-centre, open-label randomized controlled trial of two commonly used transfusion strategies in high risk patients having cardiac surgery using a non-inferiority trial design.
- Trial name
- TRICS-III (NCT02042898)
- Testing
- Restrictive Transfusion Strategy, Liberal transfusion strategy
- Where
- 74 sites in United States, Australia and 17 more
- Volunteers
- 5,028 people
- Sponsor
- Unity Health Toronto