Clinical trials: sponsored by Universidad Complutense de Madrid
Shoulder Pain
Impact of Different Electrical Frequencies Used in Percutaneous Neuromodulation on Muscle Strength and Pressure Pain Thresholds
Percutaneous electrical nerve stimulation (PENS) involves delivering electrical currents through fine filiform needles inserted near tissues such as muscles, ligaments, or nerves.
- Trial name
- PENS-DOSE (NCT07269925)
- Testing
- Percutaneous electrical nerve stimulation: High frequency, Percutaneous electrical nerve stimulation: Low frequency
- Where
- 2 sites in Poland
- Volunteers
- 30 people
- Sponsor
- Universidad Complutense de Madrid
Implant Infection
Biofilm Accumulation in Zirconia vs. Titanium Implants
The aim of this randomized clinical trial is to compare the amount and type of biofilm formed on the surface of zirconia implants compared to titanium implants.
- Trial name
- NCT06075017
- Testing
- dental implant placement
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Dental Malocclusion, Maxillary Deficiency
Effect on Periodontal Phenotype of Flapless Piezoincission During Orthodontic Treatment
Research Question While the reduction in treatment times and the patient satisfaction after periodontally accelerated osteogenic orthodontics (PAOO) are well sustained in the scientific literature, there is still controversy…
- Trial name
- Piezo_Ortho (NCT06315348)
- Testing
- flapless alveolar decortication with augmentation
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidad Complutense de Madrid
Stroke, Rehabilitation
Virtual Reality-Based Upper Limb Rehabilitation in Chronic Stroke
This randomized controlled study aims to evaluate the effectiveness of non-immersive virtual reality-based rehabilitation using the MindMotion™ GO system compared with conventional occupational therapy for improving upper limb…
- Conditions
- Stroke, Rehabilitation, Upper Limb Paresis, Chronic Stroke Patient
- Trial name
- NCT07534124
- Testing
- Non-Immersive Virtual Reality Rehabilitation, Occupational Therapy
- Where
- Spain
- Volunteers
- 26 people
- Sponsor
- Universidad Complutense de Madrid
Gingival Vascularization, Oral Soft Tissue Wound Healing
Analysis of the Reliability and Validity of Laser Speckle Contrast Imaging
This study is designed to validate laser speckle contrast imaging (LSCI) as a non-invasive method for measuring superficial gingival blood perfusion.
- Conditions
- Gingival Vascularization, Oral Soft Tissue Wound Healing, Laser Speckle Contrast Imaging, Periodontal Wound Healing
- Trial name
- LSCI (NCT07527351)
- Testing
- Laser Speckle Contrast Imaging
- Where
- Spain
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Peri-Implantational Loss, Surgical Wound
Strip Graft w/ Xenogeneic Matrix vs Free Gingival Graft for the Augmentation of Peri-implant Keratinized Mucosa
The primary objective of this study is to compare changes in peri-implant keratinized mucosa (PIKM) following the application of apically repositioned flap (ARF) using a combination of a Strip graft and a Xenogeneic matrix, or…
- Conditions
- Peri-Implantational Loss, Surgical Wound, Healing Surgical Wounds, Thin-gingiva
- Trial name
- NCT06261268
- Testing
- Strip graft with Mucograft, Free gingival graft
- Where
- Spain
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Ischemic Heart Disease
Effects of Home-based Respiratory Muscle Training Progamme in Individuals With Ischemic Heart Disease
The main objective of the present study is to verify whether respiratory muscle training programme (IMT+EMT; included both inspriratory and expiratory muscles), applied by telerehabilitation, is an effective intervention (versus…
- Trial name
- NCT06856915
- Testing
- Inspiratory muscle training, Combined inspiratory and expiratory muscle training, Conventional cardiac rehabilitation programme
- Where
- Spain
- Volunteers
- 104 people
- Sponsor
- Universidad Complutense de Madrid
Stable Coronary Artery Disease (CAD), Myocardial Infarction
Aerobic Interval vs Continuous Training on Heart Rate-Power Decoupling in Ischemic Heart Disease
This study is a randomized, parallel-group clinical trial with assessor and statistical analyst blinding, conducted at a single center.
- Trial name
- NCT07485400
- Testing
- Intervention Group, Control Group (A):
- Volunteers
- 48 people
- Sponsor
- Universidad Complutense de Madrid
Patellar Tendinopathy
Effects of HMB and Rehabilitation Program in Athletes With Patellar Tendinopathy
This randomized, double-blind, placebo-controlled clinical trial evaluates the effects of oral beta-hydroxy-beta-methylbutyrate (HMB) supplementation combined with an eccentric exercise and extracorporeal shockwave rehabilitation…
- Trial name
- HMB_TEN (NCT07466407)
- Testing
- Eccentric exercise and extracorporeal shock wave therapy, Beta-hydroxy-beta-methylbutyrate (HMB)
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Universidad Complutense de Madrid
Gingival Recession, Localized
Theravex Oral and Theravex Tissue Care Plus in the Healing Process of Mucogingival Surgery
This clinical study assesses the efficacy of two novel bioactive solutions, Theravex Oral and Theravex Tissue Care Plus, in enhancing soft tissue healing after periodontal surgery.
- Trial name
- NCT07430670
- Testing
- Modified Free Gingival Graft (M-FGG), Theravex Bioactive Solutions (Tissue Care Plus and Oral)
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Universidad Complutense de Madrid
Gingival Recession
Changes in Soft Tissue Thickness Following Multiple Coronally Advanced Tunnel (MCAT) vs Vestibular Incision Subperiosteal Tunnel Access (VISTA)
This randomized clinical trial will compare two surgical methods for treating multiple adjacent gingival recessions (types RT1 and RT2): the Modified Coronally Advanced Tunnel (MCAT) and the Vestibular Incision Subperiosteal…
- Trial name
- NCT07200258
- Testing
- Vestibular Incision Subperiosteal Tunnel Access (VISTA), Modified Coronally Advanced Tunnel (MCAT)
- Where
- Spain
- Volunteers
- 44 people
- Sponsor
- Universidad Complutense de Madrid
Skeletal Class III Malocclusion
Comparison of Maxillary Protraction Using Tooth-borne Facemask Versus Skeletal Anchorage Chin-plate in Class III Growing Patients
This retrospective non-randomized controlled clinical trial aimed to compare the skeletal and dentoalveolar effects of two orthopedic treatment protocols for skeletal Class III malocclusion in growing patients: a conventional…
- Trial name
- NCT07383259
- Testing
- Tooth-Borne Expander with Facemask (FM), Hybrid Skeletal Anchorage Expander with Chin-Plate (SA)
- Volunteers
- 36 people
- Sponsor
- Universidad Complutense de Madrid
Bone Augmentation Associated With Immediate Loading
Immediately Loaded Implants With or Without Horizontal Augmentation
This study aims to compare the clinical success and patient-reported outcomes of immediately loaded dental implants placed in sites with buccal dehiscence treated by horizontal augmentation versus immediately loaded implants…
- Trial name
- ILHA (NCT07374757)
- Testing
- guided bone regeneration technique, No intervention
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Edentulism
Accuracy of Metal Sleeve-Free Fully Guided Implant Surgery
This clinical trial aims to evaluate the in vivo accuracy of fully guided dental implant surgery using 3D-printed surgical guides without metal sleeves.
- Trial name
- NCT07364006
- Testing
- Standard Drilling Channel Metal Sleeve-Free Surgical Guide, Reduced drilling channel Metal Sleeve-Free Surgical Guide
- Where
- Spain
- Volunteers
- 15 people
- Sponsor
- Universidad Complutense de Madrid
Patellar Tendinopathy / Jumpers Knee
Long-Hold Yielding Isometric Exercise for Patellar Tendinopathy in Weightlifting Athletes
The goal of this clinical trial is to evaluate whether a long-hold yielding isometric exercise program improves pain, tendon vascularity, mechanical properties, and functional performance in weightlifting athletes with patellar…
- Trial name
- QuantFlow (NCT07361848)
- Testing
- Long-Hold Yielding Isometric Exercise Program, Usual-Care Training Condition
- Where
- Spain
- Volunteers
- 24 people
- Sponsor
- Universidad Complutense de Madrid
Oral Lichen Planus
Effectiveness of a Sodium Hyaluronate 0.01% and Sh-Oligopeptide-85 SP Mouthwash for the Treatment of Symptomatic Oral Lichen Planus
Annex 1. Patient Information and Informed Consent for the Study Study Title: Effectiveness of a sodium hyaluronate 0.01% and Sh-Oligopeptide-85 SP mouthwash for the treatment of symptomatic oral lichen planus: a randomized…
- Trial name
- NCT07280442
- Testing
- Sodium hyaluronate 0.01% and Sh-Oligopeptide-85 SP Mouthwash
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidad Complutense de Madrid
Non-specific Low Back Pain (NSLBP), Facet Joint Syndrome
Percutaneous Electrical Nerve Stimulation As Alternative To Nerve Blocks In Anesthesia, Pain Medicine And Rehabilitation Of Nonspecific Chronic Pain
Chronic musculoskeletal pain of non-specific origin affects approximately 30% of the global population. Beyond its prevalence, it represents a serious health and socioeconomic problem.
- Trial name
- PENSAR (NCT07273006)
- Testing
- Nerve block with Lidocain, Percutaneous electrical nerve stimulation
- Where
- Poland
- Volunteers
- 82 people
- Sponsor
- Universidad Complutense de Madrid
Diabetes Complications, Diabetes Education
Impact of an Educational Intervention on Ulcer Incidence, Knowledge, Self-Care, and Quality of Life in Diabetic Foot Syndrome
This randomized clinical trial assessed the impact of a structured educational intervention in patients with diabetic foot syndrome.
- Conditions
- Diabetes Complications, Diabetes Education, Diabetes Foot Care
- Trial name
- NCT07329491
- Testing
- Structured education intervention, Standard podiatry care
- Where
- Spain
- Volunteers
- 42 people
- Sponsor
- Universidad Complutense de Madrid
Partial Edentulism, Tooth Loss / Rehabilitation
In Vivo Evaluation of the Accuracy of Immediate Screw-Retained Provisional Crowns Fabricated Using Digital Planning and Guided Surgery
This clinical trial aims to evaluate the in vivo accuracy of a fully digital workflow for the immediate placement of a previously fabricated screw-retained provisional crown using digital planning and guided implant surgery.
- Trial name
- NCT07315607
- Testing
- Fully Guided Implant Placement and Immediate Provisionalization
- Where
- Spain
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Prosthesis and Implant Dentistry
Passive Fit of Implant-Supported Complete-Arch Prostheses Using Digital Workflows
The goal of this clinical trial is to evaluate and compare three digital workflows for the fabrication of definitive implant-supported full-arch prostheses in adult patients requiring fixed implant rehabilitation.
- Trial name
- MFS03-Pdental (NCT07315620)
- Testing
- CBCT-STL Alignment Workflow, Splint-Guided Alignment Workflow, Automated AI-Assisted CBCT-STL Alignment Workflow
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Universidad Complutense de Madrid