Clinical trials: sponsored by University College, London
Depression, Anxiety
Online Support Groups for Depression and Anxiety
The purpose of this study is to determine the effectiveness of online support groups for anxiety and depression.
- Trial name
- NCT01149265
- Testing
- Online support group, Expressive writing
- Where
- United Kingdom
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University College, London
Acute Coronary Syndrome
Secondary Prevention in Acute Coronary Syndromes: A CALIBER Study
All contemporary guidelines for secondary prevention in acute coronary syndromes recommend a combination of aspirin, beta-blockers, ACE-inhibitors and statins. Yet underutilisation of these drugs is common.
- Trial name
- NCT01162187
- Volunteers
- 400,000 people
- Sponsor
- University College, London
Falls
Promoting Physical Activity in the Over 65s
The aim of the project is to evaluate the delivery, impact and cost effectiveness of a community based exercise programme (FaME); compared to a home based exercise programme (OEP) supported by similarly aged mentors; compared…
- Trial name
- ProAct65+ (NCT00726531)
- Testing
- Otago Exercise Programme, Fame, Treatment As Usual
- Where
- 2 sites in United Kingdom
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- University College, London
Cytomegalovirus Infections
CMV Glycoprotein B Vaccine in Allograft Recipients
Patients who receive transplants are at increased risk of developing serious cytomegalovirus (CMV) infections because they have a decreased immune system.
- Trial name
- NCT00299260
- Testing
- CMV gB vaccine
- Where
- United Kingdom
- Volunteers
- 140 people
- Sponsor
- University College, London
Dementia
Dementia Early Recognition and Response in Primary Care
The purpose of this study is to develop and test an educational intervention for dementia in primary care, combining timely diagnosis, psychosocial support around the period of diagnosis and management concordant with guidelines.
- Trial name
- EVIDEM-ED (NCT00866099)
- Testing
- Educational Dementia training
- Where
- 2 sites in United Kingdom
- Volunteers
- 125 people
- Sponsor
- University College, London
Liver Cirrhosis
Predictive Utility of DASIMAR as a Prognostic Biomarker in Acute-on-chronic Liver Failure (ACLF)
Patients with acute on chronic liver failure have a risk of developing multiorgan failure and a high mortality. The current scoring systems defining the outcome of patients with acute decompensation of cirrhosis fail to identify…
- Trial name
- DASIMAR (NCT01071746)
- Where
- United Kingdom
- Volunteers
- 700 people
- Sponsor
- University College London Hospitals
Secondary Progressive Multiple Sclerosis
A Randomised Controlled Trial of Neuroprotection With Lamotrigine in Secondary Progressive Multiple Sclerosis
A present there is no safe treatment for reducing rate at which disability worsens in people with secondary progressive multiple sclerosis.
- Trial name
- NCT00257855
- Testing
- Lamotrigine
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- University College London Hospitals
Epilepsy
Clinical Trial of Light Therapy for Epilepsy
This study is designed to investigate whether light therapy may be an effective treatment for some people with epilepsy. Light treatment is already an established treatment for depression.
- Trial name
- NCT01028456
- Testing
- Light Therapy, 100 lux
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- University College, London
Chronic Hepatitis C Infection
The Role of Dendritic Cells in Hepatitis C Infection
The role of the dendritic cells, the most potent antigen presenting cells, in the establishment of chronic hepatitis C is not established.
- Trial name
- NCT00723242
- Testing
- Viraferon-peg and Rebetol
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- University College, London
Urologic Diseases
Pharmacology and Physiology of the Lower Urinary Tract
The function of the lower urinary tract is simple - urine storage and voiding. However, despite this simplicity of function, the control of the lower urinary tract is a rather complex, multilevel process (urothelium, detrusor…
- Trial name
- NCT00662064
- Where
- United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University College London Hospitals
Atherosclerotic Narrowing of the Superficial Femoral Artery, Atherosclerotic Occlusion of the Superficial Femoral Artery
The Safety and Efficacy of Photodynamic Therapy for Femoral Artery Stenosis
Rstenosis is common after angioplasty of atherosclerotic disease of the femoral artery. Pilot study data suggests that adjuvant photodynamic therapy, using delta amino kleavulinic acid as a photosensitiserr is feasible and safe.
- Trial name
- NCT00187811
- Testing
- Delta amino leavulinic acid photodynamic therapy
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- University College London Hospitals
Chronic Hepatitis C, HCV Genotype 1
Analysis of the Duration of Combination Therapy That is Necessary for HCV Genotype 1 Eradication
Open-label, single centre study evaluating efficacy and viral kinetics of combination PEG-IFNa2a and Ribavirin treatment on CHC genotype 1 patients, administered until viral clearance demonstrated between 4 - 12 weeks, then…
- Trial name
- NCT00152581
- Testing
- Pegylated interferon-alfa2a (Pegasys); ribavirin
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- University College London Hospitals
Sepsis, Critical Illness
Regulation of Endocrine, Metabolic, Immune and Bioenergetic Responses in Sepsis
The hypothesis of this study is that bioenergetic failure in human sepsis, related to endocrine, metabolic and mitochondrial dysfunction, is a major determinant of defective host immune responses, increasing disease severity and…
- Trial name
- NCT00187824
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University College London Hospitals