Clinical trials: sponsored by University Hospital, Angers
Chest Pain
Efficacy of the CARE Rule Associated With the HEART Score in Patients With Emergency Chest Pain
Acute coronary syndrome (ACS) is a major public health problem and its diagnosis remains a challenge for the emergency physician.
- Trial name
- eCARE (NCT04157790)
- Testing
- CARE score
- Where
- 11 sites in Belgium, France
- Volunteers
- 2,153 people
- Sponsor
- University Hospital, Angers
Facioscapulohumeral Muscular Dystrophy
Unraveling Metabolic Involvement in Facioscapulohumeral Dystrophy Through Metabolomics
The pathogenesis of facioscapulohumeral dystrophy (FSHD), one of the most prevalent types of inherited muscle disease, is unknown.
- Trial name
- METIN-FSHD (NCT06086548)
- Testing
- metabolomic on plasma sample
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Non Alcoholic Fatty Liver Disease
UDFF Performance Evaluation ((Ultrason Derived Fat Fraction)
The purpose of this study is to assess UDFF performance (compared to MRI)
- Trial name
- UDFF (NCT06080386)
- Testing
- UDFF
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Angers
Catheter-Related Infections, Catheter Complications
Impact of Tubing Colonization on the Incidence of Central Venous Catheter Infection
The objective of this study is to assess the relationship between infusion system colonization (ramps or multi-lumen devices) and the occurrence of CVC infection/colonization.
- Conditions
- Catheter-Related Infections, Catheter Complications, Catheter Infection, Catheter-related Bloodstream Infection
- Trial name
- CRIC (NCT06019897)
- Volunteers
- 200 people
- Sponsor
- University Hospital, Angers
Fasting
Observance of Preoperative Fasting Time a Before-and-after Sensitization Campaign to Fasting Guidelines Study
The goal of this before and after observational study is to evaluate the impact of a global sensitization campaign (targeted on surgeons, anesthetist and patients) about pre-operative fasting in an adult population.
- Trial name
- BreakFast (NCT05743803)
- Testing
- Sensititization campaign on preoperative fasting rules
- Where
- France
- Volunteers
- 364 people
- Sponsor
- University Hospital, Angers
Premature Birth
Evaluation of Immunization Coverage of Premature Infants Leaving CHU d'Angers According to the Recommended Regimen During the First 4 Months (VACCIPREM)
Premature children are particularly vulnerable in terms of infection and vaccinated in a specific, reinforced vaccination schedule.
- Trial name
- VACCIPREM (NCT03918096)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 384 people
- Sponsor
- University Hospital, Angers
Small Bowel Obstruction, Surgery
Enhanced Recovery Programs and Small Bowel Obstruction
Small bowel obstruction surgery is frequent and would benefit from enhanced recovery programs. While some studies advocate for their feasibility, it has never been proved and prospective studies are required to confirm the…
- Trial name
- RACO (NCT04929275)
- Testing
- Enhanced recovery program
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Angers
Negative Challenge to Amoxicillin
Outcome of Patients After a Negative Oral Challenge to Amoxicillin
This study aims to evaluate the outcome of patients who had a negative oral challenge to Amoxicillin
- Trial name
- REINAD (NCT04922034)
- Testing
- Amoxicillin
- Where
- France
- Volunteers
- 190 people
- Sponsor
- University Hospital, Angers
Food Allergy in Children, 6 Years Old Maximum
Assessment of Orality Disorders in Children With Food Allergies
Orality disorders are frequent in child. There are complications like growth and psychomotor development disorders. The aim is to estimate the prevalence of orality disorder for child with one or several food allergy.
- Trial name
- ALLERGORAL (NCT04378335)
- Testing
- completion of questionnaire
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Angers
Body Representation, Congenital Skin Disorder
Representation of Congenital Birthmarks
This descriptive cross-sectional single center study will be conducted at Angers Maternity Unit. It pertains to the ways in which healthcare professionals represent congenital birthmarks found in newborns.
- Conditions
- Body Representation, Congenital Skin Disorder, Feelings
- Trial name
- ReCONNAISSANCE (NCT06042075)
- Testing
- Questionnaire on congenital birthmarks
- Where
- France
- Volunteers
- 140 people
- Sponsor
- University Hospital, Angers
Myeloproliferative Neoplasm, Secondary Leukemia
MultiOmic characteriZation of Acute Myeloid Leukemia Evolving From myelopRoliferative Neoplasm to Identify New Targeted Therapeutic Strategies
Myeloproliferative neoplasms (MPN) are chronic myeloid malignancies characterized by a risk of evolution to acute myeloid leukemia (AML).
- Trial name
- MOZART (NCT06022341)
- Testing
- Multiomic characterization, In vitro drug screening
- Volunteers
- 120 people
- Sponsor
- University Hospital, Angers
Appendicitis
Peri-operative Analgesia for Single-incision Laparoscopic Appendectomy
Laparoscopic appendectomy is a very common intervention in pediatric surgery. To improve outcomes, some teams have developed the use of single-site laparoscopic appendectomy (SILAP).
- Trial name
- PAMAL (NCT05773521)
- Testing
- SILAP (single incision laparoscopic appendectomy)
- Where
- France
- Volunteers
- 140 people
- Sponsor
- University Hospital, Angers
Work-Related Condition
Feasibility of a Physiological Monitoring for Teleassistance to Isolated Workers in Industrial Cleaning
The purpose of the study is to test the feasibility of the monitoring of physiological parameters during operations of industrial cleaning
- Trial name
- TIGER (NCT04915560)
- Testing
- Connected T-shirt
- Where
- France
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Covid19, Microcirculation
COVID-19 Associated Endothelial Dysfunction Study
SARS-CoV-2 enters human cells through the binding of the spike protein with angiotensin converting enzyme-2 (ACE2), a membrane receptor highly expressed in immune or non-immune cells, and in many organs, including lungs and…
- Trial name
- CAUSED (NCT04773899)
- Testing
- Procedure : Multimodal microvascular assessment at study inclusion
- Where
- 2 sites in France
- Volunteers
- 75 people
- Sponsor
- University Hospital, Angers
Trauma Injury
External Validation of the Clinical Pre-hospital "Red- Flag" Alert for Activation of Intra-hospital Hemorrhage Control Response in Blunt Trauma.
External validation of the clinical pre-hospital "Red- Flag" alert for activation of intra-hospital hemorrhage control response in blunt trauma.
- Trial name
- RED-FLAG 2 (NCT05820217)
- Volunteers
- 630 people
- Sponsor
- University Hospital, Angers
Compartment Syndrome
COmpartment Syndrome vaLidation Of Non Invasive Assessment of Tissue Pressure
Chronic Compartment Syndrome (CCS) is a pathology that affects more specifically subjects exposed to repeated movements, particularly in a professional life or sports. The diagnosis is difficult and often delayed.
- Trial name
- COLONIA (NCT03840434)
- Testing
- MyotonPRO
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Angers
Aging
Interest and Feasibility of the DIGItracking Technique for the Early Diagnosis of COGnitive Disorders
The main objective is to assess the usability of a novel tool of neurocognitive disorders detection, called the Digitracking, by the elderly population.
- Trial name
- DIGICOG-start (NCT05784623)
- Testing
- User experience
- Where
- France
- Volunteers
- 135 people
- Sponsor
- University Hospital, Angers
Emergencies, Old Age; Debility
Impact of Video Regulation Associated With an Emergency Kit on Night Hospitalizations of the Residents of Nursing Homes.
The aim is to evaluate the effectiveness of the device (emergency kit and video-medical control in emergency call centers) in reducing deep night hospitalizations of elderly people living in retirement homes.
- Conditions
- Emergencies, Old Age; Debility, Nursing Caries
- Trial name
- VisioR-EHPAD (NCT05773508)
- Testing
- Video regulation and emergency kit
- Where
- France
- Volunteers
- 350 people
- Sponsor
- University Hospital, Angers
Pseudoxanthoma Elasticum, Employment
Employment of Patients With Pseudoxanthoma Elasticum
Pseudoxanthoma elasticum (PXE) is a rare, autosomal recessive genetic disease characterized by progressive calcification and fragmentation of elastic fibers in connective tissues.
- Trial name
- MEE-PXE (NCT05246189)
- Testing
- Telephone Call
- Where
- France
- Volunteers
- 99 people
- Sponsor
- University Hospital, Angers
Sleep Apnea Syndromes, Obstructive, Cancer
Exosomes Implication in PD1-PD-L1 Activation in OSAS
An increased occurrence of cancer associated mortality has been described in patients with Obstructive Sleep Apnea Syndrome (OSAS).
- Trial name
- ExoSAS (NCT03811600)
- Testing
- PD1/PD-L1 exosomal expression
- Where
- France
- Volunteers
- 90 people
- Sponsor
- University Hospital, Angers