Clinical trials: sponsored by University Hospital, Angers
Iliac Kinking
Systolic Ankle arteriaL Pressure and Transcutaneous oximetrY During a TURTLE Test in Athletes
Aim of the study is to test the feasibility of transcutaneous oxygen pressure (TcPO2) recording in the diagnosis of iliac kinking in 20 patients with suspected of endofibrosisoriliackinking and 40 asymptomatic control heathy…
- Trial name
- SALTY-TURTLE (NCT03568201)
- Testing
- Transcutaneous oximetry
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Extracorporeal Circulation; Complications
Preoperative Evaluation of Microcirculation for Prediction of Complications After Cardiac Surgery
Cardiac surgery is responsible for many complications. Microcirculation is involved in many of them. The objective of this study is to prospectively investigate the prognostic value of preoperative microcirculatory assessment in…
- Trial name
- MONS (NCT03631797)
- Testing
- Microvascular reactivity evaluation
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Angers
Thoracic Outlet Syndrome
Vascular Compression Assessment Using Transcutaneous Oxymetry in Patients Suspected of Having Thoracic Outlet Syndrome
Thoracic outlet syndrome (TOS) is characterized by nervous, venous or arterial symptoms resulting from a compression of the thoracic bundle in the thoracic outlet. The diagnostic approach of TOS is still controversial.
- Trial name
- NCT05702866
- Testing
- Transcutaneous oximetry
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Angers
Thoracic Surgery, Prehabilitation
Preoperative Inspiratory Muscle Training Effects on the Perioperative Inflammatory Reaction in Cardiac Surgery.
This study evaluates the impact of preoperative high-intensity inspiratory muscle training (IMThi) before cardiac surgery on perioperative inflammatory response.
- Conditions
- Thoracic Surgery, Prehabilitation, Respiratory Therapy
- Trial name
- EMI HiPo (NCT03158402)
- Testing
- Prehabilitation with inspiratory muscle training
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Angers
Popliteal Artery Entrapment
Physical Activity Return After Popliteal Artery Entrapement Syndrome Surgery
evaluation of physical activity return after popliteal artery entrapement syndrome surgery with the tegner activity scale
- Trial name
- PAES (NCT05584917)
- Testing
- tegner acticity scale
- Where
- France
- Volunteers
- 38 people
- Sponsor
- University Hospital, Angers
Acute Leukemia
Physical Fitness Impact of Early Physiotherapy Intervention With a Standardized Exercise Therapy Program in Adult Patients Receiving Intensive Induction Chemotherapy for Treatment of Acute Leukemia During Extended Hospitalization.
This study aimed to investigate the impact of Physical therapy in adult patients receiving intensive induction chemotherapy for the treatment of acute leukemia during prolonged hospitalization.
- Trial name
- KinHémo (NCT04899882)
- Testing
- KinHémo
- Where
- 4 sites in France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Angers
Claudication
Clinical Interest of the TcPO2 Technique
The measurement of the transcutaneous oxygen pressure records simultaneously the tcpO2 at the buttocks and chest level during walking.
- Trial name
- CINEYSOFT (NCT01808989)
- Testing
- Exercise oxymetry
- Where
- 8 sites in France
- Volunteers
- 952 people
- Sponsor
- University Hospital, Angers
Anemia, Intensive Care
Erythropoietin to Improve Critical Care Patient Outcomes
Recently, the french societies for critical care (SFAR and SRLF) produced guidelines for anemia treatment in critically ill patients that recommend the use of erythropoietin (EPO) in these patients, but the european society…
- Trial name
- EPO-ICU-FS (NCT05080049)
- Testing
- Erythropoietin
- Where
- 2 sites in France
- Volunteers
- 42 people
- Sponsor
- University Hospital, Angers
Iron-deficiency, Postoperative Complications
Impact of Iron Deficiency on the Incidence of Postoperative Infections
Iron deficiency is a common state during the perioperative period. Data from literature do not allow us to conclude on how perioperative iron deficiency influences postoperative infections occurrence.
- Conditions
- Iron-deficiency, Postoperative Complications, Postoperative Infection
- Trial name
- CARIPO (NCT04994275)
- Testing
- no intervention, but presence of ID or not
- Where
- France
- Volunteers
- 413 people
- Sponsor
- University Hospital, Angers
B Acute Lymphoblastic Leukemia, Leukemia Relapse
Identification of New Immune Factors Specific of Relapse in Childhood B Lineage Acute Lymphoblastic Leukemia
B-acute lymphoblastic leukaemia (ALL) is the most common childhood malignancy. Despite enhancement of childhood B-ALL outcome, relapses remain difficult to treat.
- Trial name
- LABMI (NCT02618109)
- Testing
- Collection of blood samples
- Where
- 18 sites in France
- Volunteers
- 119 people
- Sponsor
- University Hospital, Angers
Head Injury Trauma
Study Evaluating the Potential Impact of a Hemorrhagic Risk Stratification Score in Patients With Mild Head Trauma
Head injuries are a common reason for consultation in emergency departments. The clinical severity of head injury is assessed using the Glasgow Coma Scale (GCS).
- Trial name
- TCL (NCT04993495)
- Where
- France
- Volunteers
- 470 people
- Sponsor
- University Hospital, Angers
Small Bowel Obstruction, Conservative Management
Radiologic Score and Failure of Conservative Management of Adhesive Small Bowel Obstruction
The management of acute adhesive small bowel obstruction remains challenging for the digestive surgeon. The Bologna guidelines recommend that conservative management of aSBO.
- Conditions
- Small Bowel Obstruction, Conservative Management, Imaging
- Trial name
- PREDIFAIL (NCT05517057)
- Where
- France
- Volunteers
- 279 people
- Sponsor
- University Hospital, Angers
Lower Limb Trauma, Venous Thromboembolism
Thromboembolic Risk Stratification by TRiP(Cast) Score to Guide Physicians in Preventive Treatment Prescriptions for Patients With Lower Limb Trauma Requiring Brace or castING.
Non-surgical traumas to the lower limbs that require orthopedic immobilisation (plaster or splint) are a frequent reason for going to accident and emergency.
- Conditions
- Lower Limb Trauma, Venous Thromboembolism, Stratification
- Trial name
- CASTING (NCT04064489)
- Testing
- TRIPscore
- Where
- 15 sites in Belgium, France
- Volunteers
- 2,123 people
- Sponsor
- University Hospital, Angers
ARDS (Acute Respiratory Distress Syndrome), Electrical Impedance Tomography (EIT)
Comparison of Different PEEP Titration Strategies Using Electrical Impedance Tomography in Patients With ARDS
The aim of the this study is to assess the short term physiological effects of 3 ventilation strategies for adult patients with ARDS admitted to intensive care unit.
- Conditions
- ARDS (Acute Respiratory Distress Syndrome), Electrical Impedance Tomography (EIT), Positive End Expiratory Pressure (PEEP), Acute Lung Injury
- Trial name
- DELTA (NCT04247477)
- Testing
- Ventilation strategy
- Where
- France
- Volunteers
- 22 people
- Sponsor
- University Hospital, Angers
Sedentary Lifestyle, Cardiovascular Diseases
Physical Exercise Prescription With PEdometeR in General Practice for Patients With Cardiovascular Risk Factors - PEPPER
This study evaluates the efficacy, in terms of energy expenditure, physical activity level, quality of life, blood pressure, waist circumference and weight, of a general practice based intervention involving a personalised…
- Conditions
- Sedentary Lifestyle, Cardiovascular Diseases, Hypertension, Hypercholesterolemia
- Trial name
- PEPPER (NCT02317003)
- Testing
- Intervention PPIL, Control OR
- Where
- France
- Volunteers
- 126 people
- Sponsor
- University Hospital, Angers
Cardiovascular Diseases
Value of Ankle Pressure Index After Maximal Exercise Tests
Estimate the response of ankle to brachial pressure index to incremental maximum exercise in subjects free from prior cardiovascular disease. Estimate morbi-mortality of included patients over a 5 years follow up.
- Trial name
- VICTOR (NCT01812343)
- Testing
- Exercise test
- Where
- France
- Volunteers
- 1,760 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Hip Fractures Pathologic, Anemia
HiFIT Study : Hip Fracture: Iron and Tranexamic Acid
Fractures of the upper end of the femur, called commonly "Hip fractures" are very common, with an incidence of approximately 1.6 million cases per year worldwide.
- Trial name
- HiFIT (NCT02972294)
- Testing
- Iron Isomaltoside 1000, Tranexamic Acid
- Where
- 13 sites in France
- Volunteers
- 419 people
- Sponsor
- University Hospital, Angers
Peripheral Arterial Occlusive Disease
Sildenafil Efficacy Study on Time Walk From Peripheral Arterial Desease Patients (Stade II) With Arterial Claudication
Efffect of a single dose oral intake of sildenafil Or placebo on the walking capacity on treadmill of PAD patients with claudication
- Trial name
- ARTERIOFIL (NCT02832570)
- Testing
- Sildenafil 100mg single oral dose
- Volunteers
- 14 people
- Sponsor
- University Hospital, Angers
Iron-deficiency, Valvular Heart Disease
Impact of Iron Deficiency and Its Correction on Mitochondrial Metabolism of the Cardiomyocyte (MitoCardioFer)
Iron is involved in essential functions of the body. It allows the transport of oxygen in the blood, via hemoglobin, at the muscular level, via myoglobin, and it is also involved in cellular metabolism in general, in particular…
- Trial name
- MitoCardioFer (NCT03541213)
- Testing
- myocardial biopsy, sternal bone marrow biopsy, blood sample
- Where
- France
- Volunteers
- 55 people
- Sponsor
- University Hospital, Angers
Cerebral Palsy, Child
EEG in Children With Unilateral Cerebral Injury During Action and Action Observation(AOE)
To study the reactivity of the mu rhythm during action and action-observation by EEG in children with unilateral cerebral injury.
- Trial name
- AOE (NCT02597374)
- Testing
- EEG
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Angers