Clinical trials: sponsored by University Hospital, Angers
Peripheral Arterial Disease
First Approach for Aspirin Misuse Objective Screening
prospective interventional study. The aim is to analyse the effect of usual ongoing treatments over the microvascular cutaneous response to galvanic current application (Current induced vasodilation ; CIV) on the forearm of…
- Trial name
- FirstAMOS (NCT02997436)
- Testing
- Laser speckle flowmetry
- Where
- France
- Volunteers
- 400 people
- Sponsor
- University Hospital, Angers
Femoral Neck Fracture
Perioperative Analgesia by Femoral Perineural Catheter for Femoral Neck Fracture - Study KTcol
Therapeutic essay of phase IV, monocentric, prospective, randomized, in double-blind during 48 hours(then simple-blind),controlled by placebo.
- Trial name
- KTcol (NCT01052974)
- Testing
- ropivacaine
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Angers
Abortion, Induced
Postoperative Pain After Medical Abortion Under Local Anesthesia : Comparison of Several Analgesic Regimen
To compare postoperative analgesia by paracetamol 1gr or ketoprofen 100 mg or the combination of these two analgesics each treatment beeing allocated by randomization
- Trial name
- NCT00188071
- Testing
- paracetamol, ketoprofen, ketoprofen + paracetamol
- Where
- France
- Volunteers
- 240 people
- Sponsor
- University Hospital, Angers
Microcirculation
Use of Laser Speckle to Study Post Occlusive Reactive Hyperhemia in Healthy Subjects
The investigators aim to test the hypothesis that Laser speckle contrast imaging allows for the measurement of cutaneous blood flow following various durations of tourniquet ischemia.
- Trial name
- SpeckleShake (NCT01169974)
- Testing
- tourniquet ischemia
- Where
- France
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Kidney Tranplant
"Lived Experience, Representations and Psychic Processes in Patients Awaiting Kidney Transplantation"
The kidney transplant remains the privileged treatment of the terminal renal insufficiency. This care is complex for the patient both on a medical surgical plan and by the psychic reorganizations.
- Trial name
- LER-Psy-PAKT (NCT02690272)
- Testing
- Psychic processes
- Volunteers
- 33 people
- Sponsor
- University Hospital, Angers
Neurocognitive Disorders
VItamin K Inhibition and NeurocoGnition (VIKING)
The primary objective of this study is to determine whether patients usually taking Vitamin K Antagonists (VKAs) exhibit a poorer global cognitive performance than control patients (matched on age, gender and indication for…
- Trial name
- VIKING (NCT03276377)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Angers
Immediate Postpartum Hemorrhage
Tranexamic Acid for Preventing Postpartum Haemorrhage Following a Vaginal Delivery
The purpose of this study is to assess whether the administration of a low dose of tranexamic acid just after vaginal delivery can reduce the incidence of immediate postpartum hemorrhage, in women who receive a prophylactic…
- Trial name
- TRAAP (NCT02302456)
- Testing
- Tranexamic Acid
- Where
- France
- Volunteers
- 4,079 people
- Sponsor
- University Hospital, Angers
Renal Cancer, Nephrectomy
Study of the Variations of the Blood Pressure After Nephrectomy for Renal Cancer (VAPANCR)
This study evaluates the impact of nephrectomy in renal cancer on blood pressure and renal function. The patients will have a follow-up of their blood pressure and renal function until 6 months after their operation.
- Conditions
- Renal Cancer, Nephrectomy, Blood Pressure
- Trial name
- VAPANCR (NCT03218319)
- Testing
- Renin measurement
- Volunteers
- 200 people
- Sponsor
- University Hospital, Angers
Elderly Care
One Year Outcome of Elderly Patients Admitted to an ICU and Mechanically Ventilated
Elderly patients are increasingly admitted in the Intensive Care Unit. Short-term outcome (e.g. hospital survival) of an ICU stay is improving in this population but little data have been published on long-term outcome.
- Trial name
- SENIOREA (NCT01679171)
- Where
- France
- Volunteers
- 489 people
- Sponsor
- University Hospital, Angers
Arterial Pulsed Oxygen Saturation
Accuracy and Precision of Different Devices for the Monitoring of Pulsed Oxygen Saturation
Hypoxemia is a frequent situation in clinical practice, particularly in intensive care units or perioperative. The mortality and morbidity increase for cardiovascular reason, due to hypoxia has been reported several times.
- Trial name
- PULSEREA (NCT02832817)
- Testing
- Pulse oximeter
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Angers
ICU Acquired Weakness
Impact of Early Mobilization on Mechanical Ventilation Duration in Intubated Critically Ill Patients
The purpose of the present study is to compare usual care in terms of mobilization performed to intubated ICU patients to a standardized program designed to deliver early mobilization at least 5 days a week.
- Trial name
- EarlyMob (NCT02520193)
- Testing
- Protocolized early mobilization in ICU
- Where
- 23 sites in Belgium, France and 1 more
- Volunteers
- 772 people
- Sponsor
- University Hospital, Angers
Geriatric Disorders
Ionized Calcium and Behavioural Disorders in Older Adults (CALICO Study)
The primary objective of this study is to determine whether geriatric inpatients with severe behavioral disorders exhibit higher serum ionized calcium concentration than geriatric inpatients without behavioral disorders, but no…
- Trial name
- NCT02909491
- Where
- France
- Volunteers
- 90 people
- Sponsor
- University Hospital, Angers
Cirrhosis
Validation in a Non-targeted Population of Single Ultrasound Doppler Signs of Liver Fibrosis
The diagnosis of liver fibrosis lesions remains an important issue in patients with chronic liver diseases. The early detection of fibrosis is important for determining disease progression and postponing the evolution of chronic…
- Trial name
- DECHO2 (NCT03027921)
- Testing
- elastography
- Where
- France
- Volunteers
- 1,500 people
- Sponsor
- University Hospital, Angers
Evaluate the Risks of Using Arteriovenous Fistula as First Choise for Drug Administration
Use of Arterio-venous Fistula as First Choice for Intravenous Drug Administration in Kidney Transplant Recipients
Use of arteriovenous fistula for IV drug administration is controversial and often prohibited by nephrologists. However, we have been using this method in our department for years now in order to keep the patients 'veins for…
- Trial name
- PerFAV (NCT02874391)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Angers
Fetal Manual Rotation
RMOS Study : Impact of Manual Rotation of Occiput Posterior Position on Operative Delivery Rate (RMOS)
Introduction: The frequency of fetuses in occiput posterior position during labor is approximately 20 %, in which 5% remain occiput posterior at the end of labor.
- Trial name
- RMOS (NCT03009435)
- Testing
- prophylactic manual rotation
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Peripheral Artery Disease
Walking Estimated Limitation Calculated by History - Study 2
The purpose of this study is to test and validate a new questionnaire in order to get a "walking estimated limitation calculated by history (WELCH) in patients referred for vascular investigations.
- Trial name
- WELCH-2 (NCT01424020)
- Testing
- Questionnaire
- Where
- 18 sites in France
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Peripheral Artery Disease
Walking Impairment Questionnaire in PAD
Purpose is to test and validate a new questionnaire (the WELCH questionnaire) to estimate walking capacity in patients with claudication
- Trial name
- WELCH (NCT01114178)
- Testing
- questionnaire
- Where
- France
- Volunteers
- 340 people
- Sponsor
- University Hospital, Angers
Ischemia, Peripheral Artery Disease
Tissue Lesions in Exercise Related Ischemia
The purpose of this study is to evaluate the effect of muscle ischemia during claudication on mitochondrial function. Comparison to patients with arterial disease but absence of lower limb claudication (Cardiac group) feasibility…
- Trial name
- SARTORIUS (NCT02834351)
- Testing
- Muscle Biopsy
- Where
- France
- Volunteers
- 36 people
- Sponsor
- University Hospital, Angers
Peripheral Artery Disease
Claudication Evaluation During Rowing ExerciseS
Check the feasibility of the collection of reliable measures of tcpO2 the lower limbs in arteriopathy when performing rowing on effort.
- Trial name
- CERES (NCT02833597)
- Where
- France
- Volunteers
- 6 people
- Sponsor
- University Hospital, Angers
Obstructive Sleep Apnea Syndrome
VASO-AM :Impact of Oral Appliance Therapy on Endothelial Function in Obstructive Sleep Apnea
This is a randomized controlled study evaluating the impact of 2 months of oral appliance therapy on endothelial function in patients with severe obstructive sleep apnea syndrome intolerant to continuous positive airway pressure…
- Trial name
- VASO-AM (NCT01426607)
- Testing
- AMO
- Where
- 4 sites in France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Angers