Clinical trials: sponsored by University Hospital, Angers
Age-Related Hearing Loss, Postural; Defect
Postural Modification and Hearing Aids in Presbycusis
Presbycusis could be associated to increased risk to fall. There is little about the impact on postural balance of hearing aids.
- Conditions
- Age-Related Hearing Loss, Postural; Defect, Hearing Aid
- Trial name
- Post-AP (NCT05706051)
- Testing
- posturography
- Where
- 2 sites in France
- Volunteers
- 51 people
- Sponsor
- University Hospital, Angers
Thoracic Outlet Syndrome
Differences in Quality of Life After Thoracic Outlet Syndrome Surgery
Quality of life evaluation after thoracic outlet surgery with Quick-DASH and SF-36 forms
- Trial name
- POST-AP (NCT05426473)
- Testing
- QuickDASH form
- Where
- France
- Volunteers
- 88 people
- Sponsor
- University Hospital, Angers
Pediatric Inguinal Hernia
Development of Taxi Teaching for Strangled Inguinal Hernias in Children
Inguinal hernias in children are very common but pose a risk of strangulation, which, if not treated quickly, can lead to life-threatening complications (intestinal obstruction, peritonitis) or functional complications…
- Trial name
- DETHREAT (NCT07106515)
- Volunteers
- 104 people
- Sponsor
- University Hospital, Angers
Testicular Positioning Anomalies, Cryptorchidism
Learning to Palpate the Child's Testicles Using Simulation
Hypothesis is that better training of medical students in the examination of boy's external genitalia could improve the diagnosis of testicular position anomalies.
- Trial name
- PaTenSim (NCT07106502)
- Testing
- testicular palpation training on a mannequin
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Virtual Reality, Brain Damage
Evaluation of a Virtual Reality Tool for Identifying the Cognitive Functions of the Right Hemisphere in Patients With Brain Damage -TANGO
Evaluate the diagnostic performance of a virtual reality application to detect the presence of cognitive impairment of the non-dominant hemisphere in patients with brain damage
- Trial name
- TANGO (NCT04288505)
- Testing
- VIRTUAL REALITY application
- Where
- France
- Volunteers
- 41 people
- Sponsor
- University Hospital, Angers
Delivery, Post Partum
Evaluation of Postpartum Posttraumatic Stress Disorder at Angers University Hospital (ESPT-PP)
The purpose of this study is to estimate the prevalence of post-traumatic stress disorder (PTSD) at one month in women who have given birth at the University Hospital of Angers over a period of 1 year.
- Trial name
- ESPT-PP (NCT04160273)
- Testing
- patient questionnaire and telephone follow-up
- Where
- France
- Volunteers
- 1,451 people
- Sponsor
- University Hospital, Angers
Anaphylaxis Caused by Hymenoptera Venom (Disorder)
Hymenoptera Venom Immunotherapy: Evaluation of Its Long-term Efficacy at the University Hospital of Angers (EFLOTITA2)
Allergy to Hymenoptera venom is one of the main causes of anaphylaxis in adults, and is less common in the paediatric population. It can be severe or even fatal.
- Trial name
- EFLOTITA2 (NCT05311644)
- Testing
- Telephone survey
- Where
- France
- Volunteers
- 290 people
- Sponsor
- University Hospital, Angers
Pediatric Cancer, Cancer Survivor
LOG-I - Impact Study of LOG-AFTER Software on Long-term Monitoring of Former Patients (LOG-I - LOG-Impact Study)
Childhood cancer survivors represent a high-risk population that requires risk-based follow-up. Follow-up recommendations have been harmonized.
- Conditions
- Pediatric Cancer, Cancer Survivor, Hemato-oncologic Patients
- Trial name
- LOG-I (NCT06939322)
- Testing
- Use of the Log-AFTER software
- Where
- France
- Volunteers
- 320 people
- Sponsor
- University Hospital, Angers
Chronic Low Back Pain
VRFR- Immersive Virtual Reality Use in a Spine Functional Restoration Program - A Feasibility Study
This clinical trial investigates the feasibility of integrating immersive virtual reality (VR) technology into a functional restoration program (FRP) for patients with chronic low back pain (CLBP).
- Trial name
- VRFR (NCT06724679)
- Testing
- Utilisability of an immersive VR device in a functional restoration program (FRP) for patients with chronic low back pain.
- Where
- 5 sites in France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Angers
Postoperative Ileus, Surgery-Complications
Intestinal Microbiota and Postoperative Ileus After Colorectal Surgery
Postoperative ileus (POI) after colorectal surgery is frequent and is a burden for national health authority because it increases the morbidity and the length of hospital stay.
- Trial name
- MICRO-IPO (NCT05512741)
- Testing
- Feces collection
- Where
- France
- Volunteers
- 64 people
- Sponsor
- University Hospital, Angers
Importance of Interictal Epileptiform Activity on Sleep EEG, Epilepsy in Children
Effect of Sulthiame on EEG in Childhood Epilepsy Syndromes
The effect of sulthiame on EEG has been studied in epilepsy syndromes of childhood with sleep activation by comparing sleep EEG obtained at baseline and after 4 weeks of treatment.
- Trial name
- SURF (NCT05885646)
- Testing
- Sulthiame
- Where
- 3 sites in France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Angers
Shock, Acute Circulatory Failure
Concordance Study of Therapeutic Decision-making in Patients With Shock Based on Hemodynamic Monitoring
Shock is a serious complication corresponding to acute circulatory failure resulting in multiorgan failure and death. In order to improve cellular oxygen utilization, several therapies can be used.
- Conditions
- Shock, Acute Circulatory Failure, Hemodynamic Monitoring
- Trial name
- PICC-ECHO (NCT05613647)
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Angers
Solid Cancers
Real-life Performance Evaluation of the LiFlow X-ray Platform
The thoraco-abdomino-pelvic (TAP) scanner is crucial for assessing and monitoring solid cancers. However, advancements in scanner technology have led to a significant increase in data volume, from 100 images per exam 20 years ago…
- Trial name
- LiFE (NCT06999538)
- Testing
- Radiologist interpretation
- Volunteers
- 400 people
- Sponsor
- University Hospital, Angers
Sleep Apnea, COPD Exacerbation
Impact of Continuous Positive Airway Pressure on the Occurrence of Acute Exacerbations of COPD in Patients With COPD-OSA Overlap Syndrome (CO-OS)
Chronic Obstructive Pulmonary Disease (COPD) and Obstructive Sleep Apnea (OSA) are both frequent respiratory diseases with estimated prevalences between 8 and 15% of the adult population.
- Conditions
- Sleep Apnea, COPD Exacerbation, Overlap Syndrome
- Trial name
- SLEEPOVEA (NCT05958563)
- Testing
- continuous positive airway pressure treatment
- Where
- 15 sites in France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Angers
Pain, Postoperative, Cardiac Surgery
Chest Wall Block After Sternotomy: Randomized Controlled Trial in Cardiac Surgery: (PABLOS Study)
The main objective is to compare the effectiveness of LocoRegional Anesthesia (LRA) (bilateral transverse thoracic block or bilateral parasternal block) in addition to standard management compared to standard management alone…
- Trial name
- PABLOS (NCT05345639)
- Testing
- LRA Loco-regional anesthesia, Standardized post-operative analgesia protocol
- Where
- France
- Volunteers
- 254 people
- Sponsor
- University Hospital, Angers
Predisposition, Genetic, Cancer Childhood
EXOme Rare Cancers in Children (EXOCARE)
Other than high-dose radiation and previous chemotherapy, few strong risk factors have been identified as causes of childhood cancer.
- Conditions
- Predisposition, Genetic, Cancer Childhood, Development Delay
- Trial name
- EXOCARE (NCT03472807)
- Testing
- Collection of blood sample or saliva, Collection of a tumor sample taken before the participation of the patient in study, Collection of blood sample if tumor sample is not available
- Where
- 27 sites in France, Reunion
- Volunteers
- 169 people
- Sponsor
- University Hospital, Angers
Thoracic Outlet Syndrome
Systematic Transcutaneous Oxymetry Use in Thoracic Outlet Syndrome
The measurement of the transcutaneous oxygen partial pressure (TCPO2) at exercise is, to our knowledge, the only method to estimate during the exercise the importance of ischemia segment of limb by segment of limb bilaterally and…
- Trial name
- STOUT (NCT03355274)
- Testing
- Transcutaneous Oximetry, Photopletysmography, Questionnaires of Quality of Life (QoL)
- Where
- France
- Volunteers
- 222 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Chronic Myeloid Leukemia (CML)
Evaluation of a Cardiovascular Active Prevention in Chronic Myeloid Leukemia on the Cardiovascular Morbi-mortality
According to the French National Cancer Institute, 35 000 new hematologic cancers are observed in France representing 10% of the new cancers.
- Trial name
- PALERMO (NCT03746054)
- Testing
- Optimal medical treatment, usual clinical practice
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Angers
Health Knowledge, Attitudes, Practice, Nurse Training
Impact of Simulation-Based Training on the Safety of Medication Administration
Task interruption is part of professional life. The healthcare world is not exempt from this phenomenon. Task interruptions lead to errors and increase the risks in managing patients.
- Conditions
- Health Knowledge, Attitudes, Practice, Nurse Training, Simulation
- Trial name
- SIM-SAM (NCT05543655)
- Testing
- high fidelity simulation
- Where
- France
- Volunteers
- 25 people
- Sponsor
- University Hospital, Angers
Acute Respiratory Failure
Surface Mechanomyography Using a Parasternal Patch to Measure and Detect Respiratory Drive and Effort
Surface mechanomyography (sMMG) has been proposed as a tool to study muscle mechanical activity. sMMG is a noninvasive technique using specific transducers to record muscle surface oscillations due to mechanical activity of the…
- Trial name
- PATCH-MMG (NCT06046898)
- Testing
- non-invasive ventilation with or without resistance
- Where
- France
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers