Clinical trials: sponsored by University Hospital, Angers
Myeloproliferative Disorder, Essential Thrombocythemia
Pilot Study for the Development of a Diagnostic Score to Differentiate Myeloproliferative Neoplasms.
Prospective study for the development of a non-invasive score for differentiating prefibrotic myelofibrosis from essential thrombocytosis and overt myelofibrosis.
- Conditions
- Myeloproliferative Disorder, Essential Thrombocythemia, Primary Myelofibrosis, Prefibrotic Stage, Primary Myelofibrosis, Fibrotic Stage
- Trial name
- BioScoreSMP (NCT03869476)
- Testing
- Non-invasive diagnosis score
- Where
- 2 sites in France
- Volunteers
- 133 people
- Sponsor
- University Hospital, Angers
Breast Asymmetry, 3D
MEasurement by a Numerical Approach of BREAst Volume
Breast asymmetry is a rare in plastic surgery. In majority of cases, it is idiopathic. In cases that are poorly tolerated physically (vertebral imbalance, posture disorders) or psychologically, the decision to perform breast…
- Trial name
- MENABREA (NCT03715738)
- Testing
- arm 1 : Creaform3D + MyotonPRO
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Cancer Childhood, Febrile Neutropenia
Clusterin, Ptx3 and Pediatric Febrile Neutropenia (CluPPFeN)
Febrile aplasia is a common occurrence in children/adults treated with chemotherapy for malignant blood diseases or solid cancers.
- Trial name
- CluPPFeN (NCT05584930)
- Testing
- Collection of blood sample
- Where
- France
- Volunteers
- 55 people
- Sponsor
- University Hospital, Angers
Mucositis Oral, Stem Cell Transplant Complications
Evaluate the Efficacy of Selenium for the Prevention of Chemotherapy-induced Mucositis During Autologous Stem Cell Transplantation.
Chemotherapy-induced mucositis is an important complication after autologous stem cell transplantation. It is mainly responsible for pain and dysphagia requiring opioids and artificial nutrition.
- Trial name
- AutoSelenium (NCT04080622)
- Testing
- Selenium
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Angers
Charcot-Marie-Tooth Disease Type 2A
Metabolomic Exploration of Dysregulated Lipid Metabolism in MFN2-related CMT2A (MetaDLM_CMT2A)
Charcot-Marie-Tooth (CMT) disease is the commonest sensitivo-motor inherited peripheral neuropathies with a prevalence of about 10-30 per 100,000. To date, more than 80 genes have been found responsible for CMT.
- Trial name
- NCT04881201
- Testing
- blood sample
- Where
- France
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Surgical Complications, Device Safety
Complications of the Cephalic Route in Implantable Site Placement in Children
Totally implantable venous access devices (TIVADs) offer long-term central venous access for children requiring intravenous treatments.
- Trial name
- SitePedia (NCT06644885)
- Testing
- TIVAD implantation complications
- Volunteers
- 426 people
- Sponsor
- University Hospital, Angers
Anesthesia
PABLOS 2.0 - Chronic Pain After Sternotomy
The PABLOS study (NCT05345639) recently realised at the University Hospital of Angers looked at the place of loco-regional anesthesia (LRA) in the optimization of analgesia and the early post-operative recovery of patients…
- Trial name
- PABLOS2 (NCT06534775)
- Testing
- Questionnary
- Where
- France
- Volunteers
- 253 people
- Sponsor
- University Hospital, Angers
Fractures, Bone
Boneview-ED - Impact of Artificial Intelligence Detecting Fractures in the Emergence Department : a Pragmatic Prospective Study
Traumatic emergencies are the primary reason for consultation in emergency departments and standard radiography is the primary imaging exam for osteoarticular trauma.
- Trial name
- Boneview-ED (NCT06013852)
- Testing
- processing the radiography with the "Boneview" software
- Where
- France
- Volunteers
- 1,600 people
- Sponsor
- University Hospital, Angers
Metastatic Renal Cancer
Ketogenic Diet for Patients Receiving Treatment for Metastatic Renal Cell Carcinoma
The purpose of this study is to evaluate the tolerance of one year of ketogenic diet associated with vitamin supplementation in patients treated for a metastatic renal cell carcinoma.
- Trial name
- CETOREIN (NCT04316520)
- Testing
- Ketogenic diet
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Angers
Tonsillectomy, COVID-19
Impact of a History of Tonsillectomy or Adenoidectomy on the Severity of COVID-19 : AMYVID Study
Little is known about the impact of tonsillectomy and/or adenoidectomy on the severity and presentation of respiratory infections, let alone COVID-19.
- Conditions
- Tonsillectomy, COVID-19, Adenoidectomy
- Trial name
- NCT05935566
- Testing
- health questionnaire
- Sponsor
- University Hospital, Angers
Septic Shock
Effects of Norepinephrine and Volume Expansion in Capillary Refill Time in Septic Shock in Angers University Hospital
the purpose of this study is to assess the effect of norepinephrine and fluid expansion on capillary refill time during septic shock.
- Trial name
- NOVECAR-A (NCT05325957)
- Where
- France
- Sponsor
- University Hospital, Angers
Chronic Diseases in Children
User Experience of a Gait Training Treadmill for Home Rehabilitation of Children With Chronic Conditions
"In the context of limited accessibility to prolonged and efficient rehabilitation programs based on physical activity, this study aims to develop a home program for children with chronic diseases affecting physical health…
- Trial name
- EMMVIES-UX (NCT06552819)
- Testing
- No intervention
- Where
- France
- Volunteers
- 75 people
- Sponsor
- University Hospital, Angers
Rare Intellectual Disabilities
Multi-Omics and IPSCs to Improve Diagnosis of Rare Intellectual Disabilities
Background Genetic factors play a major role in intellectual disability (ID) but the underlying cause is not determined in many cases.
- Trial name
- MIDRID (NCT03635294)
- Testing
- Blood sample
- Where
- 6 sites in France
- Volunteers
- 7 people
- Sponsor
- University Hospital, Angers
Anemia
Accuracy of Non Invasive Hemoglobin Measure by SpHb Device in Post Operative Anemia Diagnosis
Non invasive Hemoglobin monitoring by SpHb device had been developed to assess Hemoglobin level during hemorrhagic surgery. It's accuracy to detect post operative anemia on a single post operative measure has been recently…
- Trial name
- SpHb_gyneco (NCT06497335)
- Testing
- non invasive hemoglobin measure
- Volunteers
- 150 people
- Sponsor
- University Hospital, Angers
Anemia
Efficiency of Patient Blood Management Protocol in Gynecological Surgery Department (PERIOPESGYNECO)
Perioperative anemia is associated with higher risk of red blood cell transfusion, higher rates of morbimortality and lower quality of postoperative recovery.
- Trial name
- PERIOPESGYNECO (NCT06493435)
- Volunteers
- 160 people
- Sponsor
- University Hospital, Angers
Pediatric Obesity
Qualitative Evaluation of Pediatric Obesity Therapeutic Education Programs
Obesity concerns almost the entire planet and is considered in France as a major public health issue: 17% of children are overweight and 4% obese.
- Trial name
- QUALIPOP (NCT06488235)
- Volunteers
- 32 people
- Sponsor
- University Hospital, Angers
Infertility
Conversion of in Vitro Fertilization Cycles to Intrauterine Inseminations in Patients With a Poor Ovarian Response to Stimulation
The purpose of this study is to compare the efficiency of conversion to IUI and IVF in patients with a poor ovarian response to stimulation
- Trial name
- ConFIRM (NCT03362489)
- Testing
- IVF / IVF-ICSI, IUI
- Where
- 32 sites in France, Guadeloupe
- Volunteers
- 462 people
- Sponsor
- University Hospital, Angers
Small Bowel Obstruction
Early Surgery Versus 3 Days Non-surgical Management in Acute Small Bowel Obstruction (SURGI-BOW)
For uncomplicated acute small bowel obstruction (aSBO), the "Bologna guidelines" recommend non-surgical management of 72 hours before considering surgery.
- Trial name
- SURGI-BOW (NCT06065150)
- Testing
- Standard support, Early surgery proposed according to the radiological score
- Where
- 14 sites in France
- Volunteers
- 630 people
- Sponsor
- University Hospital, Angers
Endothelial Dysfunction
Circulating Exosomes and Endothelial Dysfunction in Patients With Obstructive Sleep Apneas Hypopneas Syndrome
Evaluation of miRNA contained in exosomes in obese and OSA patients with endothelial dysfunction evaluated by digital plethysmography (ENDOPAT) compared to obese and OSA patients without endothelial dysfunction.
- Trial name
- EXODYS (NCT04459182)
- Testing
- ENDOPAT
- Where
- France
- Volunteers
- 99 people
- Sponsor
- University Hospital, Angers
Renal Disease
Evaluation of a Screening Strategy of Fabry Disease in Patient With Renal Biopsy
Fabry disease is genetic X linked disease, with annual incidence of 1 in 100,000 that is certainly underestimate the true prevalence of the disease.
- Trial name
- HISTOFAB (NCT03869554)
- Testing
- Detection of Fabry disease
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Angers