Clinical trials: sponsored by University Hospital, Angers
Physical Activity, Aged
Study of an Physical Exercise Program on Older People of 75 Years Old and More, Hospitalized in Geriatric Short Stay
The main objective is to assess the effect, compared to usual care, of a nursing accompaniment or nursing assistant intervention in the physical activity of patients hospitalized in the geriatric stay, on the daily number of…
- Trial name
- ACTI-PACT (NCT04327115)
- Testing
- "Control" strategy, "Intervention" strategy
- Where
- France
- Volunteers
- 864 people
- Sponsor
- University Hospital, Angers
End-stage Renal Disease
Evaluation of the Level of Expression of CD45RC on T Lymphocytes as a Predictive Biomarker of Acute Rejection After Renal Transplantation
Chronic renal failure is a major public health problem in industrialized countries, due to its frequency - about 3 million patients in France - and its socio-economic impact.
- Trial name
- ECLAT (NCT03994497)
- Testing
- Blood samples
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Angers
Sleep Apnea, Inflammation
PTP1B Implication in the Vascular Dysfunction Associated With Obstructive Sleep Apnea
Obstructive sleep apnea (OSA) syndrome is associated with increased vascular dysfunction and atherosclerosis. Especially, it has been shown that OSA associated intermittent hypoxia represents a pro inflammatory stimulus resulting…
- Conditions
- Sleep Apnea, Inflammation, Atherosclerosis
- Trial name
- MacroSAS (NCT04235023)
- Testing
- myeloid PTP1B expression analysis
- Where
- France
- Volunteers
- 58 people
- Sponsor
- University Hospital, Angers
Aortic Aneurysm and Dissection
MITAORTA - Role of Mitochondrial Dynamic in Aneurysm and Dissection of Ascending Thoracic Aorta
The main objective is to compare the mitochondrial dynamic between patients operated for aneurysm of ascending aorta or type A aortic dissection (AAD) or control group
- Trial name
- MITAORTA (NCT05434481)
- Testing
- Mitochondrial dynamic analysis in the aorta samples and metabolomic profiling in the aortic diseases
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Thoracic Outlet Syndrome
TULIP et MASC : Premiers Usages
The aim of this work is to propose two new questionnaires (TULIP and MASC) which are simple to complete by the patient, quick to analyze and can be calculated directly by the physician, adapted to the general population, whether…
- Trial name
- TEMPUS (NCT05441176)
- Testing
- Questionnaires
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Angers
Musculoskeletal Disorder, Rotator Cuff Tendinitis
Body Schema Alterations in Musculoskeletal Disorders : Effect of Laterality
This study assess ocular movements in a hand laterality judgment task in a population of musculoskeletal disorders. Reaction time, error rate and visual strategy are compared between musculoskeletal disorders and healthy…
- Conditions
- Musculoskeletal Disorder, Rotator Cuff Tendinitis, Chronic Low Back Pain, Carpal Tunnel Syndrome
- Trial name
- Schem-TMS (NCT03567109)
- Testing
- hand laterality judgment task
- Where
- France
- Volunteers
- 71 people
- Sponsor
- University Hospital, Angers
Allergy
Hemp Seed Awareness
Hemp is a plant of the Cannabaceae family. Cannabis sativa, derived from female flowers, is the first illicit substance used by adolescents and is a major public health problem.
- Trial name
- ARCHANGE (NCT04841954)
- Testing
- hemp prick-test
- Where
- France
- Volunteers
- 600 people
- Sponsor
- University Hospital, Angers
Preterm Birth
AttachMent Preterm in the Loire Infant Follow-up Team
The purpose of this study is to describe the attachment representations of children born prematurely at age 3 and 5 with regard to their neurocognitive and behavioral development.
- Trial name
- AMPLIFy (NCT04304846)
- Testing
- Questionnaires and interviews
- Where
- 2 sites in France
- Volunteers
- 90 people
- Sponsor
- University Hospital, Angers
Consciousness Disorder
Feasibility Study of Virtual Reality to Promote the Awakening of Patients in a State of Minimal Consciousness
Advances in neurosurgery and neuroresuscitation have improved patients' prognosis. However, 2% of serious head injuries progress to a vegetative state, this condition persisting at 1 year for 1% of these patients.
- Trial name
- REVEIL (NCT04978857)
- Testing
- autobiographic movie
- Where
- France
- Volunteers
- 8 people
- Sponsor
- University Hospital, Angers
Venous Disease
Volume Estimation of the Limb After VEnous Treatment
Chronic venous disease encompasses a broad spectrum of clinical presentations and is considered the most common vascular disease.
- Trial name
- VELVET (NCT03703765)
- Testing
- lower limb volume estimation
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Angers
Venous Thromboembolism, Deep Vein Thrombosis
Inter-observer Reliability of the TRiP(Cast) Score in Patients With Trauma to a Lower Limb Requiring Immobilisation
The aim of the study isto evaluate the inter-observer reliability of the assessment of venous thromboembolic risk using the TRiP(cast) score in patients presenting with trauma to a lower limb requiring immobilisation, and of the…
- Conditions
- Venous Thromboembolism, Deep Vein Thrombosis, Pulmonary Embolism, Thromboprophylaxis
- Trial name
- CCASTING (NCT06416280)
- Testing
- Assessment of the TRiP(cast) score
- Where
- France
- Volunteers
- 302 people
- Sponsor
- University Hospital, Angers
Cardiac Rehabilitation, Acute Coronary Syndrome
Using a Connected Application to Maintain Physical Activity After Cardiac Rehabilitation
Maintaining physical activity after cardiac rehabilitation has a major role in disease progression and patient prognosis. 6 months after the cardiac rehabilitation, we find during a nursing interview that many patients do not…
- Conditions
- Cardiac Rehabilitation, Acute Coronary Syndrome, Heart Failure
- Trial name
- APA&CO2 (NCT05646849)
- Testing
- Connected application
- Where
- France
- Volunteers
- 208 people
- Sponsor
- University Hospital, Angers
Hyperplasia
TREC - Evaluation of the Impact of Eversion Technical Features on the Rate of Carotid Restenosis
Restenosis due to myo-intimal hyperplasia remains a concern after carotid endarterectomy. It occurs in around 6% of cases. Several risk factors for restenosis have already been identified, such as smoking, hypertension, female…
- Trial name
- TREC (NCT06272305)
- Testing
- This research does not require any specific investigation and does not imply any modification of treatment.
- Volunteers
- 500 people
- Sponsor
- University Hospital, Angers
Early Rehospitalization of the Elderly
Early Rehospitalization of Persons Aged 75 Years or Older Admitted to a Geriatric Post-emergency Unit.
The older population is increasing, and one of the challenges is to prevent functional disability. Longer hospital stays are a recognized factor in dependency.
- Trial name
- BACK-UPUG (NCT06239935)
- Volunteers
- 687 people
- Sponsor
- University Hospital, Angers
Incretins, Osteoporosis
The Role of Incretins in Bone Remodeling in Humans
The role of incretins (GIP and GLP-1) on cells and bone tissue has been shown in cellular and animal studies. In humans, the role of these hormones is mainly studied in the pathophysiology of diabetes, their effect on bone is…
- Conditions
- Incretins, Osteoporosis, Bone Remodeling, Healthy
- Trial name
- INCREMOS (NCT03966261)
- Testing
- blood sample
- Where
- France
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Sarcopenia, Hepatobiliary Disease
Evaluation of the Sarcopenia in Hepatobiliary Surgery
The sarcopenia is defined as a loss of muscle mass and a loss of muscle function ( strength or performance). Some studies showed that the sarcopenia increase the postoperative complications and the overall survival in abdominal…
- Conditions
- Sarcopenia, Hepatobiliary Disease, Postoperative Complications, Surgery
- Trial name
- SARFO (NCT03754452)
- Where
- France
- Volunteers
- 45 people
- Sponsor
- University Hospital, Angers
ARDS
Comparison of Volume Assist Control, Dual Mode and Airway Pressure Release Ventilation.
The aim of the COMIX-R study is to assess the short term physiological effects of 3 ventilation strategies for adult patients with ARDS admitted to intensive care unit
- Trial name
- COMIX-R (NCT04196738)
- Testing
- ventilation strategy
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Angers
Loiasis With Positive Blood Microfilaremia
Assessment and Treatment of Loiasis With Positive Microfilaremia
Loiasis is a vector-borne filariasis endemic in the forested areas in Central Africa whose incidence and morbi-mortality are poorly understood.
- Trial name
- LoPoMi (NCT06194149)
- Volunteers
- 200 people
- Sponsor
- University Hospital, Angers
Cardiopulmonary Arrest, Mechanical Ventilation Complication
Evaluating the Performance of Invasive Ventilation During Specialized CPR
Describe the ventilation patterns, describe the evolution of ventilation over time and describe the safety data for two strategies of ventilation (volume or pression modes) during specialized cardiopulmonary resuscitation of…
- Trial name
- NCT06175689
- Volunteers
- 400 people
- Sponsor
- University Hospital, Angers
Type 1 Diabetes, Treatment
Influence of Type 1 Diabetes (T1DM) Treatment Type on Mental Workload
Influence of the type of treatment for type 1 diabetes (pump versus multiple injections versus closed loop) on the treatment burden of children and adolescents and their parents.
- Trial name
- CHAM&DIAB (NCT06165159)
- Testing
- children and adolescents with type 1 diabetes and their parents
- Where
- France
- Volunteers
- 800 people
- Sponsor
- University Hospital, Angers