Clinical trials: sponsored by University Hospital, Brest
Chronic Obstructive Pulmonary Disease, Cardiovascular Insufficiency
Validation of a Walk-Time Limit Test (WTLT) Derived from the 6-Minute Walk Test (6-MWT) in Patients with Chronic Cardiovascular or Respiratory Diseases
Many exercise tests are commonly used to evaluate the changes of exercise tolerance following rehabilitation programs in patients with chronic respiratory diseases.
- Trial name
- TTLM (NCT04086953)
- Testing
- 6-minute walk test, Walk-Time Limit Tes, Incremental shuttle walk test
- Where
- France
- Volunteers
- 44 people
- Sponsor
- University Hospital, Brest
Gonococcal (GC) Infection, Arthritis, Infectious
Epidemiology of Gonococcal Arthritis (EpGAr)
The aim of this retrospective observational study was to describe the epidemiology of Neisseria gonorrhoeae septic arthritis over the last 10 years at Brest and Rennes university hospitals.
- Trial name
- EpGAr (NCT06897943)
- Where
- 2 sites in France
- Volunteers
- 11 people
- Sponsor
- University Hospital, Brest
Harm Reduction, Prisoners
Assessment of the Perceptions and Opinions of Staff Working of Prisons and Detention Centers on the Use of Psychoactive Substances in Prisons and Harm Reduction (PERRCEP)
Evaluation, through an anonymous questionnaire, of the perceptions and opinions of staff working in prisons and detention centers in Brittany regarding the consumption of illicit substances and harm reduction measures in prison…
- Trial name
- PERRCEP (NCT06894589)
- Where
- France
- Volunteers
- 800 people
- Sponsor
- University Hospital, Brest
Acute Renal Failure, Hemorrhage
Impact of Renal Replacement Therapy on Coagulation Profile of Patients with Acute Renal Failure
Renal failure and high plasmatic level of urea have been associated with an increased risk of hemorrhage in surgical patients. There is only sparse data on the impact of renal replacement therapy on homeostatic parameters.
- Conditions
- Acute Renal Failure, Hemorrhage, Coagulation Disorder
- Trial name
- HEMOSTIR (NCT03536195)
- Where
- France
- Volunteers
- 14 people
- Sponsor
- University Hospital, Brest
Pulmonary Embolism, Proximal Deep Vein Thrombosis
Six Years of Follow-up After Idiopathic Venous Throbmoembolism
Beyond the first 6 months of anticoagulation, patients with a first episode of unprovoked venous thromboembolism have a high risk of recurrence after stopping anticoagulations.
- Trial name
- Padis-Ext (NCT02884934)
- Where
- 10 sites in France
- Volunteers
- 409 people
- Sponsor
- University Hospital, Brest
Gonarthrosis, Arthroplasty
Rehabilitation with Personalized Strategies According to Muscle Volume Before Knee Arthroplasty
Preoperative rehabilitation before total knee arthroplasty (TKA) has not been proven to be effective. Latest meta-analyzes do not find any improvement of motor performance during gait 6 months after surgery.
- Trial name
- REPERAGE (NCT04318197)
- Testing
- Personalized rehabilitation program with electrostimulation, Global rehabilitation program
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Brest
Anxiety Disorders
Improvement of Anxiety Management During a Venous Puncture About Children with a Participatory Entertainment Method
The purpose of this study is to demonstrate an anxiety decrease about children 3 to 6 years during a venous puncture with the "fabrique à histoire".
- Trial name
- PEDIPAIN (NCT04200196)
- Testing
- "fabrique à histoire", Usual care
- Where
- France
- Volunteers
- 116 people
- Sponsor
- University Hospital, Brest
Carbapenemase-Producing Enterobacteriaceae
Prevention of Carbapenemase-producing Enterobacteriaceae Epidemics: Evaluation of a Simplified Contact Screening Policy (CADECO)
In France, carbapenemase-producing Enterobacteriaceae (CPE) are a significant concern due to their emergence. Efforts to limit their spread focus on reducing antibiotic selection pressure and preventing patient-to-patient…
- Trial name
- CADECO (NCT06839911)
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Brest
Prostatic Neoplasms
Prostate Hyperfixation on PET-choline in Patients With Prostate Cancer: Correlation With MRI and Pathological Data (LOC-CHOLINE)
In France, when prostate cancer is suspected, multiparametric MRI is the reference imaging technique for tumor localization, and is used to guide biopsies in order to characterize the tumor as accurately as possible.
- Trial name
- LOC-CHOLINE (NCT06836154)
- Where
- France
- Volunteers
- 70 people
- Sponsor
- University Hospital, Brest
Study of Venous Drainage of the Cranio-Cervical Junction Using MRI
Venous Drainage of the Craniocervical Junction: a Retrospective Anatomical Study (SVCR MR1)
This study aims to examine the feasibility of distinctly visualizing the different cervical venous networks (subcutaneous, muscular, extra-canalicular, and intra-canalicular) using dedicated magnetic resonance imaging (MRI)…
- Trial name
- SVCR MR1 (NCT06815848)
- Where
- France
- Volunteers
- 160 people
- Sponsor
- University Hospital, Brest
Adult Scoliosis, Spine Deformity
Perioperative Morbidity in Adult Scoliotic Surgery: Analysis of a Series From Brest (MOSCA-B)
Scoliosis surgery is an invasive procedure essential for alleviating significant pain and improving the physical, psychological, aesthetic, professional, and social well-being of patients.
- Conditions
- Adult Scoliosis, Spine Deformity, Neurosurgery
- Trial name
- MOSCA-B (NCT06815861)
- Where
- France
- Volunteers
- 48 people
- Sponsor
- University Hospital, Brest
Venous Thromboembolism
Recurrence of Thromboembolic Venous Disease of Atypical Location (RUSE)
RUSE is a retrospective data-based study designed to assess the frequency, characteristics and phenotype of documented recurrences of thromboembolic venous disease in atypical locations.
- Trial name
- RUSE (NCT06815874)
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Brest
Von Willebrand Diseases
Cardiovascular and Venous Thromboembolism Disease in Patients with Von Willebrand Disease in the French West
Due to increasing of life expectancy, patients with von Willebrand disease are exposed to age-related pathologies such as cancer or cardiovascular diseases.
- Trial name
- TWIGO (NCT05773638)
- Where
- 6 sites in France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Brest
Cardiac Surgery
Study of Prognostic Factors in Interventional Rhythmology
Develop a prospective register assessing the short- and long-term complications of patients undergoing interventional rhythm
- Trial name
- PRINT (NCT03099057)
- Testing
- follow-up of patients after interventional rhythm operation
- Where
- France
- Volunteers
- 2,805 people
- Sponsor
- University Hospital, Brest
Advanced Non Small Cell Lung Cancer
Retrospective Observational Study on Prediction of Response to PD-1 Immunotherapy in Patients with NSCLC
Therapeutic antibodies that block the programmed death-ligand 1 (PD-L1)/programmed death-1 (PD-1) pathway have revolutionized immuno-oncology by inducing robust and durable responses in patients with various cancer including…
- Trial name
- PREDICTION (NCT04886401)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Brest
Transplant; Complication, Failure
EVEROLD LONG TERM FOLLOW-UP
Long Term Follow up of EVEROLD study
- Trial name
- EVEROLD FUP (NCT06504225)
- Where
- 14 sites in France
- Volunteers
- 260 people
- Sponsor
- University Hospital, Brest
PICC Line Placement
COMPLI-PICC: Study on Picclines' Complications
This is a prospective monocentric study of PICC Line complications use in 5 medical and one surgical units of Brest Medical University Hospital.
- Trial name
- COMPLI-PICC (NCT03017911)
- Testing
- Piccline
- Where
- France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Brest
Clinical and Radiographic Success in 24 Months
Treatments of the Necrosed Immature Teeth (REV)
Estimate if the technique of revascularisation pulpaire (with some hydroxide of calcium) allows to obtain a better forecast of preservation of the tooth without complication than the conventional technique with the creation of an…
- Trial name
- NCT02064517
- Testing
- MTA, Hydroxide of calcium
- Where
- 3 sites in France
- Volunteers
- 16 people
- Sponsor
- University Hospital, Brest
Alcohol Abuse
Influence of Alcohol Marketing Stimuli in Adults With Regular Alcohol Consumption
Alcohol use is the second leading cause of preventable death after smoking. The Evin law was built in 1991 with the goal of reducing exposure to alcohol marketing among the youngest.
- Trial name
- DEPREV_Phase_2 (NCT05125783)
- Testing
- questionnaire
- Where
- 7 sites in France
- Volunteers
- 287 people
- Sponsor
- University Hospital, Brest
Cardiac Surgery
Interest of the Not Invasive Ventilation Used in Meadow and Post-operative of Cardiac Surgery
After cardiac surgery, many complications can arise, in particular at the cardiac and lung level and it is true especially as the patient is with comorbidity.
- Trial name
- CAPVNI (NCT02302300)
- Testing
- Manufacturer STELLAR 150
- Where
- France
- Volunteers
- 216 people
- Sponsor
- University Hospital, Brest