Clinical trials: sponsored by University Hospital, Brest
Marathon, Physical Activity
Glycemic Control Before, During and After the 2016 Paris Marathon
This is an observational mono-centric retrospective study carried out at the University Hospital of Brest The main objective of this study is to assess the glycemic control before, during and after the 2016 Paris Marathon in…
- Conditions
- Marathon, Physical Activity, Type 1 Diabetes Mellitus, Education
- Trial name
- MARADIAB (NCT04926298)
- Where
- France
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Primary Sjögren Syndrome
Eye Dryness Evaluation in Primary Sjögren's Syndrome
The objective of this observational study is to develop new tools to assess primary Sjögren's syndrome (pSS) symptoms and to measure the severity of eye involvement in these patients.
- Trial name
- PEPSS (NCT03614299)
- Testing
- Ecological symptom measurements using a webapp, Interferometry
- Where
- France
- Volunteers
- 45 people
- Sponsor
- University Hospital, Brest
Pulmonary Embolism
Comparison of 3 Diagnostic Strategies of PE: Planar V/Q Scan, CTPA, and V/Q SPECT.
Pulmonary embolism (PE) remains a diagnostic challenge. False negative testing exposes patient to the risk of potentially fatal recurrence.
- Trial name
- SPECTACULAR (NCT02983760)
- Testing
- Planar V/Q-based strategy, CTPA-based strategy, V/Q SPECT-based strategy
- Where
- 11 sites in Canada, France and 1 more
- Volunteers
- 611 people
- Sponsor
- University Hospital, Brest
Chronic Obstructive Pulmonary Disease Overlap Syndrome, Asthma
Combined Neuromuscular Electrical Stimulation for Quadriceps and Triceps During Pulmonary Rehabilitation in COPD
Patients with COPD frequently have muscle disorders. Pathogenic mechanisms generate significant pathophysiological changes in the locomotor muscles structure, leading to decreased strength, decreased endurance and limited…
- Trial name
- COMBIELEC (NCT04684966)
- Testing
- Neuromuscular Electrical Stimulation
- Where
- France
- Volunteers
- 266 people
- Sponsor
- University Hospital, Brest
Deep Vein Thrombosis
Single Complete Compression Ultrasonography to Rule Out Deep Vein Thrombosis During Pregnancy and Postpartum
The objective of the EDVIGE study is to determine whether a negative single distal and proximal leg veins compression ultrasonography safely rules out the diagnosis of deep vein thrombosis in pregnant and post-partum women with…
- Trial name
- EDVIGE (NCT00740454)
- Testing
- Lower limb veins compression ultrasonography
- Where
- 2 sites in France, Switzerland
- Volunteers
- 200 people
- Sponsor
- University Hospital, Brest
Sjogren's Disease
Tolerance and Efficacy of Rituximab in Sjogren's Disease
CLINICAL PHASE II INDICATION Sjogren's syndrome RATIONALE Sjögren's syndrome (SS) is an autoimmune disorder affecting 0.2% to 3% of the general population.
- Trial name
- TEARS (NCT00740948)
- Testing
- Rituximab (mabthera) Injection
- Where
- 14 sites in France
- Volunteers
- 122 people
- Sponsor
- University Hospital, Brest
Children with Chronic Illnesses Affecting Physical Health
Impact of the "Kid'EM App" Digital Guidance Tool for Setting Rehabilitation Goals by the Rehabilitation Professional for Children with Chronic Conditions Impacting Physical Health (READ'APP'T)
On an individual level, the first expected benefit for the child using the "Kid'EM app" would be an improvement in the quality of his or her rehabilitation goals, which would be more Specific, Measurable, Activity-related…
- Trial name
- READ'APP'T (NCT06475950)
- Testing
- Kid'EM app" experimental group, Kid'EM app control group
- Where
- 36 sites in France
- Volunteers
- 252 people
- Sponsor
- University Hospital, Brest
Sicca Syndrome, Xerostomia
Tolerance and Efficiency of an Intrabuccal Biological Film to Enhance Oral Dryness Sensation: The "PREDELFI" Clinical Pilot Study
Xerostomia affects at least a quarter of the population. This prevalence is increased in postmenopausal women and people over 65 years of age.
- Trial name
- PREDELFI (NCT04206826)
- Testing
- PREDELFI, CONTROL
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Brest
Sensitive Skin
Quantitative Sensory Testing in Subjects With Sensitive Skin or Not
Sensitive skin is a common problem, with 50% of women and 30% of men in Europe feel they have sensitive skin. The Quantitative sensory testing (QST) is a physico-psychic method that uses gradients stimuli of different modalities…
- Trial name
- SENSISKIN (NCT03081403)
- Testing
- Quantitative Sensory Testing
- Where
- France
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Multimorbidity
The Reported Frequency of FP Visits and Family Difficulties Should Alert FPs and Help Them to Prevent Severe Outcomes in Multimorbid Outpatients
The European General Practitioners Research Network (EGPRN) designed and validated a comprehensive definition of multimorbidity using a systematic literature review and qualitative research throughout Europe.
- Trial name
- NCT03116061
- Testing
- Questionnaire
- Volunteers
- 96 people
- Sponsor
- University Hospital, Brest
Lymphedema
A 3D Tablet Sensor Approach to the Measurement of a Lymphedema
Up to now, the diagnosis of lymphedema remains hard and delayed. It suffers from many limitations such as lack of coordination and formation of the health-care network.
- Trial name
- LO3D (NCT04821440)
- Testing
- Water displacement volumetry, Three dimension volumetry
- Where
- 2 sites in France
- Volunteers
- 42 people
- Sponsor
- University Hospital, Brest
Systemic Lupus Erythematosus
Systemic Lupus Erythematosus Within the Framework of the Multidisciplinary Consultation
Diagnosis and follow up of a lupus cohort in a multidisciplinary consultation in Brest ( France)
- Trial name
- CO LUPUS (NCT04320680)
- Testing
- description of a lupus patient cohort
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Brest
COPD
Effect of Different Form of Upper Limb Muscles Training on Dyspnea in COPD
Evaluate the effect of upper limbs strength training versus the effect of upper limbs endurance training, on dyspnea, in patients with COPD during a pulmonary rehabilitation program.
- Trial name
- REHABSUP (NCT03611036)
- Testing
- Strength training, Endurance training
- Where
- 2 sites in France
- Volunteers
- 280 people
- Sponsor
- University Hospital, Brest
Patients Having Realized a Suicide Attempt
Short Message System (SMS) Monitoring Intended for the Suicidal Patients
The study wants to prove that SMS monitoring reduced the number of suicide attempts in six months according to the beginning of its implementation in the group of the patients benefiting SMS compared with the group of patients…
- Trial name
- NCT02106949
- Testing
- SMS contact with patient after discharge in intervention group
- Where
- 13 sites in France
- Volunteers
- 530 people
- Sponsor
- University Hospital, Brest
Subacute Stroke
Rehabilitation Robotics After a Stroke
Upper limb motor control after a stroke may be improved with rehabilitation robotics at a subacute stage. The aim of this multicenter controled randomized single blind study is to define the place of rehabilitation robotics at…
- Trial name
- REM_AVC (NCT01383512)
- Testing
- ARMEO Spring, Self rehabilitation
- Where
- 23 sites in France
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Dysphonia, Connective Tissue Disease
Characterization of "Bamboo" and Other Vocal Cord Lesions Responsible for Dysphonia in Patients With Systemic Autoimmune Diseases (BAMBOO)
The goal of this multicenter retrospective observational study is to provide an inventory of the specific and non specific cord vocal lesions that can cause dysphonia in patients with systemic autoimmune diseases.
- Conditions
- Dysphonia, Connective Tissue Disease, Vasculitis
- Trial name
- BAMBOO (NCT06779799)
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Brest
Whipple Disease
Biological Evolution of Whipple's Disease (WHIP)
Whipple's disease (WD), a rare systemic infection by Tropheryma whipplei, lacks research on biological abnormalities pre- and post-treatment. This study explores these abnormalities for their diagnostic and monitoring value.
- Trial name
- WHIP (NCT06776484)
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Brest
Lateral Epicondylitis
Efficacy of One or Two Botulinum Toxin Injections in the Treatment of Chronic Lateral Epicondylalgia: a Retrospective Study (EPITOX)
Despite being a self-limiting injury, lateral epicondylitis (LE) can be difficult to manage. In cases of refractory LE, conservative treatment fails and symptoms persist over 6 months.
- Trial name
- EPITOX (NCT06765694)
- Testing
- Botulinum toxin injection
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Brest
ARDS (Acute Respiratory Distress Syndrome), AKI - Acute Kidney Injury
Renal Recovery After PEEP Weaning in ARDS (RE2SDRA)
The purpose of the study is to investigate renal recovery in ARDS after PEEP weaning. The primary outcome was the variation of the hourly urine output (HUO), 48 h after PEEP weaning.
- Trial name
- RE2SDRA (NCT06754787)
- Where
- France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Brest
Serous Otitis, Tympanic Membrane Perforation
Otological Study of Facial Cleft Patients Over 10 Years of Age (Excluding Isolated Cleft Lip) (EFEOF)
Studies published on the placement of transtympanic ventilatory tubes in children with cleft palate show heterogeneous results, highlighting the need for a new study with strong statistical power and long-term follow-up to…
- Conditions
- Serous Otitis, Tympanic Membrane Perforation, Retraction Pocket, Cholesteatoma
- Trial name
- EFEOF (NCT06738927)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Brest