Clinical trials: sponsored by University Hospital, Brest
Perioperative Complication, Myocardial Injury
Development of a New Prognostic Assessment Tool for Postoperative Myocardial Injury
Myocardial injury after noncardiac surgery (MINS) is common, silent, and strongly associated with morbi-mortality. There are some evidences in the littérature showing that troponin elevation pre and/or postoperatively and…
- Trial name
- TROPUTILE (NCT04286685)
- Where
- 2 sites in France
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Suicide, Attempted
Suicide Sleep Monitoring (Ssleem)
Promising results have shown that interventions to reduce insomnia diminish suicidal ideation. A better understanding of the bidirectional mechanism between sleep disturbances and suicide behavior will allow the design of…
- Trial name
- SSLEEM (NCT03068598)
- Testing
- PulseOn watch/Suunto Spartan Ultra watch
- Where
- France
- Volunteers
- 29 people
- Sponsor
- University Hospital, Brest
Gastrointestinal Bleedings
Efficacy of Small Bowel Preparation in Capsule Endoscopy
The best preparation of small bowel is still unknown. The primary aim of this study is to evaluate the polyethylene glycol (PEG) impact of small bowel preparation for unexplained gastrointestinal bleeding exploration.
- Trial name
- PREPINTEST (NCT01267981)
- Testing
- Standard diet, Standard Diet + 500 ml of polyethyleneglycol, Standard diet + 2 liters of polyethylene glycol the day before + 500ml of polyethylene glycol
- Where
- 17 sites in France
- Volunteers
- 858 people
- Sponsor
- University Hospital, Brest
Chronic Disease, Lumbago
Relevance of the Activ'Dos App for Chronic Low Back Pain Patients
The purpose of this study is to compare a self rehabilitation program using ACTIV'DOS app versus using a standard sheet of paper.
- Trial name
- ACTIV'DOS (NCT04725344)
- Testing
- ACTIV'DOS group, Usual practise
- Where
- 4 sites in France
- Volunteers
- 19 people
- Sponsor
- University Hospital, Brest
Addiction, Alcohol
Impact of a Brief Motivational Intervention Including Counter-marketing Arguments With a Population of Patients With Moderate to Severe Alcohol Use Disorders Who Are Followed up on an Outpatient Basis (Primary Care or Addictology) (DEPREV_Phase 3)
Alcohol consumption is the second cause of avoidable death after tobacco. The Evin law was constructed in 1991 with the aim of reducing exposure to alcohol marketing among the youngest.
- Trial name
- NCT04881500
- Testing
- Motivational interview, Routine Care
- Where
- 6 sites in France
- Volunteers
- 83 people
- Sponsor
- University Hospital, Brest
Hidradenitis Suppurativa
Validation of the French Version of the Score on Quality of Life (HiSQOL) in Hidradenitis Suppurativa (QUALIVER)
Validation of the French Version of the Score on Quality of Life in Hidradenitis Suppurativa. The French HiSQOL will be completed by 60 patients with hidradenitis suppurativa a first time, and a second time 1 week later.
- Trial name
- QUALIVER (NCT05986825)
- Testing
- Verneuil questionnaire Validation
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Brest
Rehabilitation, Elderly Person
Evaluation of the Concordance of Five Times Sit To Stand Results Between a Physical Consultation and a Teleconsultation
This study concerns elderly person aged more than 65 years with autonomous mobility. It is a multicentric randomized trial in two arms : Arm one : remote consultation then physical consultation Arm two : physical consultation…
- Conditions
- Rehabilitation, Elderly Person, Teleconsultation
- Trial name
- TELETEST (NCT06365177)
- Testing
- Physical consultation, Teleconsultation
- Where
- 2 sites in France
- Volunteers
- 108 people
- Sponsor
- University Hospital, Brest
Myeloproliferative Disorders
Characterization of Myeloproliferative Neoplasia With a Mutated IDH, SRSF2 or SF3B1 Allele (CARPEDIEM)
Retrospective study assessing the impact of IDH1/2, SRSF2 or SF3B1 mutations on event free survival of MPN patients
- Trial name
- CARPEDIEM (NCT06481345)
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Brest
Myeloproliferative Neoplasm
Diagnostic Characterization and Evolution of "Triple Negative" Thrombocytosis (CASTETTE)
Evaluation of Event free survival in patients with triple-negative thrombocytosis
- Trial name
- CASTETTE (NCT06481332)
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Brest
Myeloproliferative Neoplasm, Inflammatory Disease
Observatory of Patients With MyeloProliferative Neoplasm Treated With Anti-inflammatory Immunotherapy
The study will collect cases of MPN patients who also benefit from an anti-inflammatory immunotherapy for another disease. Efficacy and tolerability of the drug will be assessed in this population.
- Trial name
- OPIUM (NCT06476535)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Brest
Metastatic Melanoma
PET/CT Whole-body Dynamic Acquisition at FDG to Metastatic Melanoma Under Immunotherapy
The value of 4D body-to-whole dynamic acquisition in FDG PET / CT to differentiate progression / pseudo-progression during the first therapeutic assessment (PET1) of metastatic melanoma treated with immune checkpoint inhibitors…
- Trial name
- IMMUNOPET2 (NCT04272658)
- Testing
- value of 4D body-to-whole dynamic acquisition in FDG
- Where
- France
- Volunteers
- 56 people
- Sponsor
- University Hospital, Brest
Alopecia Areata
Evaluation of the Efficacy of Systemic Treatments for Alopecia (ESTAA)
The aim of our study was to retrospectively assess the efficacy and safety of systemic treatments in patients with alopecia areata, by recruiting cases from the HUGO network (Hôpitaux Universitaires du Grand Ouest), a network of…
- Trial name
- ESTAA (NCT06471114)
- Where
- France
- Volunteers
- 250 people
- Sponsor
- University Hospital, Brest
Myeloproliferative Neoplasm
Exploring the Impact of Monocytes in Myeloproliferative Neoplasia (EMYNEM)
Impact of monocytes on Myeloproliferative Neoplasm hematopoietic stem cell growth and differentiation in vitro
- Trial name
- EMYNEM (NCT06462664)
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Brest
Frailty
Implementation Study of the ICOPE Program for the Detection of Frailty in the Elderly Within the Territorial Health Professional Communities (CPTS) of Brest Region
Frailty is a geriatric syndrome resulting from a decrease in physiological reserve capacities altering the mechanisms of adaptation to stress with, in the absence of diagnosis and management, a short-term risk of falls…
- Trial name
- ICOPE 29 (NCT05541731)
- Where
- 2 sites in France
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Cystic Fibrosis
Patienthèque of Finisterian (South of Brittany) Children With Cystic Fibrosis in the Time of Precision Medicine
The objective of this study is to evaluate the relevance of Porphyromonas as a biomarker predicting the risk of P. aeruginosa primocolonization in children form 0 to 18 years old with cystic fibrosis.
- Trial name
- MUCOthèque (NCT04137133)
- Testing
- collection
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Brest
Sports Injury, Prevention
Evaluation of Invisible Preparation Behaviors of Middle and High School Students in Sports Facilities (PRICELESS)
The investigators define the Invisible Preparation (IP) as the set of health behaviors that young athletes implement, on their own, to optimize their health and performances.
- Conditions
- Sports Injury, Prevention, Training, Hydration
- Trial name
- PRICELESS (NCT06361771)
- Where
- France
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Colonic Neoplasms
Comparison of MORbidity of Submucosal DIssection Resection of Giant cOlon Lesions Versus Surgery: a National Multicenter Study (MORDIGO)
Propose a one-piece endoscopic resection such as endoscopic submucosal dissection (ESD) rather than surgery for benign lesions and superficial T1 cancers colorectal cancers offers comparable efficacy with better tolerability.
- Trial name
- MORDIGO (NCT06371898)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Brest
Hydration
Study of Hydration Levels in Sports and Non-sports Schoolchildren (EHC)
New knowledge regarding the negative impact of poor hydration on health highlights the need to provide recent epidemiological data on the water intake of the French population, especially among middle school students, a group…
- Trial name
- EHC (NCT06170554)
- Where
- France
- Volunteers
- 259 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Delirium
The ABCDEF Bundle in Critical Care: a French National Survey Still a Long Way to go!
The goal of this observational study is to evaluate the knowledge and compliance of French intensive care units with the ABCDEF (A: Assessment, Prevention, Management of Pain, B: Both Spontaneous Awakening Trials and Spontaneous…
- Trial name
- NCT06344013
- Where
- France
- Volunteers
- 341 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Mental Disorder, Child
Association Between a Biological Pattern of Dysregulation of the HPA Axis and Mental Disorders in Children Exposed to Early Life Stress
The purpose of this study is to demonstrate an association between a biological pattern of dysregulation of the HPA axis and mental disorders in children exposed to early life stress.
- Trial name
- ESASP (NCT04363112)
- Testing
- Mini Kid II
- Where
- France
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest