Clinical trials: sponsored by University Hospital, Brest
Cardiovascular Risk Factors
Cardiovascular Disease Prevention in Europe and Sub-Saharan Africa
Cardiovascular disease (CVD) is the leading cause of death in the world. 17.5 million people died in 2012 due to CVD (31% of all causes of death). In Europe more than 50% of deaths are due to CVD.
- Trial name
- Spices_phase_2 (NCT03886064)
- Testing
- Multi-behavioral intervention
- Where
- 2 sites in France
- Volunteers
- 583 people
- Sponsor
- University Hospital, Brest
Hemiplegia
Seated - Standing Passage of the Hemiplegic
This is a study for a new mechanical transport device adapted to the hemiplegic patients. Healthy volunteers : After explaining the protocol and presenting the movement laboratory, the subjects are equipped with reflective…
- Trial name
- PADH2 (NCT03117699)
- Testing
- New device for seated-standing passages
- Where
- 2 sites in France
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Thromboembolic Venous Disease
New Genetic Mutations in Thromboembolic Venous Disease Idiopathic. Study "FIT GENETIQUE".
Identify new genetic mutations predisposing to an increased risk of VTE by locating and / or identifying genes involved in subjects at high risk for thrombotic and in whom screening for detectable hereditary thrombophilia was…
- Trial name
- Fit-Génétique (NCT02841085)
- Testing
- Genetic sample
- Where
- France
- Volunteers
- 613 people
- Sponsor
- University Hospital, Brest
Renal Insufficiency, Chronic
Interest of the Peak of Reticulocytes in Chronic Hemodialysis Patients Treated by Mircera Hemodialysis Population
Patients under hemodialysis treatment are mostly treated by erythropoietin (EPO) through erythropoiesis stimulating agents (ESA).
- Trial name
- RETICERA (NCT02832323)
- Testing
- Reticera
- Where
- 9 sites in France
- Volunteers
- 94 people
- Sponsor
- University Hospital, Brest
Catheter-related Bloodstream Infection
Comparison of Early Phase Infections Risk Between Midline and Piccline Caheters: MIDLINE AND PICCLINE CATHETERS
A long-term venous access is frequently required in patient management. Currently, it is ensured by using the long peripheral intravenous catheters (Midline) or peripheral inserted central catheters (PICC line).
- Trial name
- PICCORMID (NCT05264402)
- Where
- France
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Sensitive Skin, Cosmetic Exposure
Impact of Exposure to Cosmetics on Sensitive Skin
The concept of sensitive or reactive skin was evoked in 1947 and developed in the 1970s and is now widely recognized. The international pruritus society has proposed an international consensus definition: sensitive skin is…
- Trial name
- SENSICOS (NCT03958968)
- Where
- 2 sites in France
- Volunteers
- 161 people
- Sponsor
- University Hospital, Brest
Pruritus, Brain Tumor
Prevalence of a Localized or Diffuse Pruritus in a Population With One or Several, Primitive or Secondary, Brain Tumor(s)
The association between the presence of pruritus, especially centrofacial, and the presence of a brain tumor is a widespread notion in the medical community but based on a single publication by Andreev et al.
- Trial name
- PRURI-C (NCT03673878)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Brest
Adenocarcinoma of the Prostate
Prediction of Lymph Node Invasion for Prostate Adenocarcinoma
Despite lymph node involvement (LNI) being one of the main prognostic factors in patients with prostate cancer (PCa), pelvic lymph node irradiation remains debated, possibly due to an insufficient selection of patients.
- Trial name
- PRED-NCHIR (NCT04909957)
- Where
- France
- Volunteers
- 400 people
- Sponsor
- University Hospital, Brest
Urogenital Abnormalities, Prenatal Disorder
Fetal Ano-genital Distance in 2D Ultrasound.
The purpose of this study is to determine a threshold value of fetal anogenital distance in 2D ultrasound to differentiate male fetuses from female fetuses, starting 18 weeks of gestation and until the due date.
- Conditions
- Urogenital Abnormalities, Prenatal Disorder, Sex Development Disorder
- Trial name
- DAG (NCT03898440)
- Where
- France
- Volunteers
- 318 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Severe Trauma, General Anaesthesia
Association Between a Peri-traumatic Dissociation State and the Occurrence of Post-traumatic Stress Syndrome
Patients will be selected after studying clinical records.Patients who had general anesthesia due to an injury related to severe trauma within 6 to 12 months prior to inclusion will be included.
- Trial name
- DIStress-AG (NCT03930966)
- Testing
- PDEQ, PCL-5 and demographic survey
- Where
- France
- Volunteers
- 148 people
- Sponsor
- University Hospital, Brest
Anorexia
Body Image Disorder in Anorexia Nervosa and Virtual Reality
Evaluation of the tolerance and acceptability of the virtual representation of its body image.
- Trial name
- REVAM (NCT03118921)
- Testing
- Virtual reality
- Where
- France
- Volunteers
- 17 people
- Sponsor
- University Hospital, Brest
Atopic Dermatitis
Effects of an Anti-TRPM8 in the Atopic Dermatitis Pruritus
The aim of the study is to analyse the effect of the menthoxypropanediol, a derivative of menthol, on the pruritus of atopic dermatitis (ex vivo study).
- Trial name
- DA-TRPM8 (NCT03610386)
- Testing
- Adding menthoxypropanediol to the biopsy, No adding menthoxypropanediol to the biopsy
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Brest
Post Operative Atrial Fibrillation
Evaluation and Monitoring of the Protocol Post Operative Atrial Fibrillation
Objectives The aims of this study is to evaluate the efficacy and tolerance of our post-operative AF management protocol after cardiac surgery, including beta-blockers, digoxin, amiodarone.
- Trial name
- ETOFIB (NCT05165862)
- Where
- France
- Volunteers
- 54 people
- Sponsor
- University Hospital, Brest
Blood Sample
Study of the Effect of the Benfluorex
More than 5 million persons in France exposed, in last years, to the taking of the Benfluorex. Arisen, at certain patients, of a valvulopathy characterized by mitrals and/or aortic leaks Withdrawal of the French market: nov.
- Trial name
- MEDIAGENE (NCT02008552)
- Testing
- Sampling of blood
- Where
- 7 sites in France
- Volunteers
- 346 people
- Sponsor
- University Hospital, Brest
Colorectal Neoplasms Malignant, Colonoscopy
Sensitivity of Fecal Immunochemical Test (FIT) for Colorectal Cancer (CRC) Screening
Fecal immunochemical test (FIT) was introduced in France late 2015, FIT has better diagnostic accuracy for colorectal cancers (CRCs) than previous screening tests.
- Conditions
- Colorectal Neoplasms Malignant, Colonoscopy, Early Detection of Cancer, Female
- Trial name
- FITBACK (NCT05163236)
- Testing
- Positive fecal immunochemical test (FIT), Negative fecal immunochemical test (FIT), Fecal immunochemical test (FIT) not performed
- Where
- France
- Volunteers
- 1,149 people
- Sponsor
- University Hospital, Brest
Prostate Cancer
Innovative Planning and Guidance System for Prostate Focal Brachytherapy
A key feature of low-dose brachytherapy is that irradiation affects only a local area around the inserted radiation sources. The exposure of healthy tissues around these sources is then reduced.
- Trial name
- FOCUS (NCT03160365)
- Testing
- ACQUISITION OF IMAGES
- Where
- France
- Volunteers
- 34 people
- Sponsor
- University Hospital, Brest
Pain
Central Neuromodulation of Pain Through Music in Healthy Subjects
The present research aims to study the neuromodulatory effect of music on the sensory component of pain. The activation of pain control systems, through music, would pave the way for rehabilitation prospects for patients with a…
- Trial name
- DOUMU1 (NCT03914105)
- Testing
- Without music, With music
- Where
- France
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Rectal Cancer
Prediction of the Response to Neoadjuvant Radiation Chemotherapy Through Texture Analysis Derived From Medical Imaging
In patient with complete pathological response, surgery could be omitted without compromising progression-free or overall survival. A powerful prediction model is needed to guide management of this population.
- Trial name
- RECTOMICS (NCT04920435)
- Where
- 3 sites in France
- Volunteers
- 124 people
- Sponsor
- University Hospital, Brest
Cerebral Palsy
Evaluation of Functional, Neuroplastic and Biomechanical Changes Induced by an Intensive, Playful Early-morning Treatment Including Lower Limbs (EARLY-HABIT-ILE) in Preschool Children With Uni and Bilateral Cerebral Palsy
An urgent priority in the field of paediatric neurorehabilitation is the development of effective early motor interventions. Hand and Arm Bimanual Intensive Therapy Including Lower Extremities (= HABIT-ILE) applies the concepts…
- Trial name
- HABIT-ILE (NCT04017871)
- Testing
- MRI, Electro-Encephalography-High Density (children with unilateral PC only), 3D and EMG analysis
- Where
- 2 sites in France
- Volunteers
- 42 people
- Sponsor
- University Hospital, Brest
Chronic Sinusitis
Evolution of the Endonasal Microbiota in Patients With Chronic Rhinosinusitis
Chronic rhinosinusitis (CRS) is defined according to the French society of otorhinolaryngology as chronic non-mechanical damage to the nasal structures, excluding infectious damage to the sinus structures.
- Trial name
- METEL-RC (NCT04418622)
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Brest