Clinical trials: sponsored by University Hospital, Brest
Systemic Lupus Erythematosus (SLE)
3TR (Taxonomy, Treatment, Targets and Remission) Systemic Lupus Erythematosus Study Protocol 2
The natural history of Systemic lupus erythematosus (SLE) is characterized by relapses or flares alternated with periods of remission.
- Trial name
- 3TR-SLE2 (NCT05747651)
- Testing
- Blood sample, Urine sample, Saliva sample
- Where
- France
- Volunteers
- 6 people
- Sponsor
- University Hospital, Brest
Cystic Fibrosis
Non-invasive Prenatal Diagnosis of Monogenic Disorders by Linked-reads Technology
Description of the presence of cell-free fetal DNA in maternal plasma allowed the possibility of non-invasive prenatal diagnosis.
- Trial name
- NID (NCT03622892)
- Where
- 6 sites in France
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Heart Failure
Effect of Personalized Follow-up in Adapted Physical Activities in Subjects With Chronic Heart Failure.
France has one million people with heart failure (HF). Exercise intolerance, characterised by dyspnoea, is the main clinical symptom in HF patients and a key determinant of reduced quality of life.
- Trial name
- BougeTonCoeur (NCT06222762)
- Testing
- Experimental arm
- Where
- 2 sites in France
- Volunteers
- 90 people
- Sponsor
- University Hospital, Brest
Schizophrenia Prodromal, Schizophrenia, Childhood
Patientheque in Patients With a Psychosis
Establishment of a patient library for patients who have had a first psychotic episode and who have an "at risk" status for psychotic disorder (GRD, APS, BLIPS group) or a psychosis threshold during CAARMS administration.
- Conditions
- Schizophrenia Prodromal, Schizophrenia, Childhood, Schizophrenia
- Trial name
- LONGIPEP (NCT05340348)
- Testing
- Blood samples (36 mL) + fecal samples + hair sample
- Where
- France
- Volunteers
- 250 people
- Sponsor
- University Hospital, Brest
Superficial Adenopathy
Predictive Character Analysis of Ganglionic Echography for the Diagnostic of Benin or Malignant Superficial Adenopathy
Investigators need to establish a formal diagnostic of superficial adenopathy through complementary investigations to find etiologic diagnostic ( Echography, adenogram).
- Trial name
- EGAS (NCT02645825)
- Sponsor
- University Hospital, Brest
Tolerance, Biopsy Site Itching
SAfety and TOlerance of the Biopsies in Auto-immune Rare dIseases
Biopsies are performed in several autoimmune diseases to diagnose or classify them Tolerance and information of the patients have been poorly evlauated our objective is to evaluate tolerance and information of the patients after…
- Trial name
- SATORI (NCT05022420)
- Where
- 8 sites in France
- Volunteers
- 505 people
- Sponsor
- University Hospital, Brest
Chronic Respiratory Disease
The Benefits of Individualized Follow-up With a Sport-Health Professional in the Care of Patients With Chronic Respiratory Diseases
Pulmonary rehabilitation is an integral part of care for patients with chronic respiratory diseases. It improves patients' physical capacities, quality of life and symptoms, at least in the short term.
- Trial name
- WANTTOMOVE (NCT06579612)
- Testing
- Personalized follow-up and support
- Where
- 2 sites in France
- Volunteers
- 352 people
- Sponsor
- University Hospital, Brest
Premature Birth
Effect of the IBAIP in Preterm Infants Neurodevelopment
Mortality in very preterm infants has decreased significantly over the past twenty years. However, neuromotor, behavioral and cognitive development disorders are more common in these children born before 33 weeks of gestation as…
- Trial name
- IBAIP (NCT04685356)
- Testing
- IBAIP : Infant Behaviour Assessment and Intervention Program, Standard Support, Ages and Stages Questionnaire (ASQ)
- Where
- 9 sites in France
- Volunteers
- 240 people
- Sponsor
- University Hospital, Brest
Sjogren's Syndrome
B-dependant Rare AutoImmune diseaSES - Cohort of Patients With Suspected Diagnosis of Primitive Sjögren Syndrome
The objectif is to study the diagnosis performance of the different classification criteria in reference to the gold standard consisting of the diagnosis made by expert doctors after standardized assessment, of pSS (primary…
- Trial name
- BRAISES-DiaPSS (NCT04931160)
- Testing
- Blood, fluid, sells and urine samples
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Brest
Systemic Lupus Erythematosus (SLE)
3TR (Taxonomy, Treatment, Targets and Remission) Systemic Lupus Erithematosus Study Protocol
The natural history of Systemic lupus erythematosus (SLE) is characterized by relapses or flares alternated with periods of remission.
- Trial name
- 3TR-SLE1 (NCT05458622)
- Testing
- Blood sample, Urine sample, Saliva sample
- Where
- France
- Volunteers
- 25 people
- Sponsor
- University Hospital, Brest
Autoimmune Diseases
Study of STIM1 Membrane Expression
The aim of this study is to determine the expression of STIM1 in the plasma membrane of lymphocytes from patients suffering from different autoimmune diseases in order to identify new pathologies of interest presenting an…
- Trial name
- STIMEX (NCT04978948)
- Where
- 4 sites in France
- Volunteers
- 670 people
- Sponsor
- University Hospital, Brest
Idiopathic Inflammatory Myopathies
Adult Autoimmune Myopathies (MAIA)
This study corresponds to a monocentric prospective cohort of adult patients presenting a suspicion of idiopathic inflammatory myopathy.
- Trial name
- MAIA (NCT04792931)
- Testing
- description of adult autoimmune myopathies
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Brest
Myelodysplastic Syndromes, Myelodysplastic Anemia
Biocollection in MyeloDysplastic Syndrome (P-MDS)
Myelodysplastic syndromes (MDS) are chronic myeloid hemopathies characterized by ineffective hematopoiesis (with peripheral cytopenias) and which contrast with a marrow of normal richness.
- Conditions
- Myelodysplastic Syndromes, Myelodysplastic Anemia, Myelodysplastic Syndrome With Isolated Del(5Q), Myelodysplastic Syndrome With Ring Sideroblasts
- Trial name
- P-MDS (NCT04869683)
- Testing
- description of MDS pzatient cohort
- Where
- France
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Diabetes Type 1
French Version of the Scales of Fear of Hypoglycaemia in Children With Type 1 Diabetes and Their Parents
Type 1 diabetes usually appears brutally in children or young adults. While many factors of poor glycemic balance have been identified in the literature (age, socio-cultural and socio-economic level, family structure, adherence…
- Trial name
- FHS (NCT03529188)
- Where
- 3 sites in France
- Volunteers
- 194 people
- Sponsor
- University Hospital, Brest
Primary Sjögren Syndrome
Inflammatory Myopathies in Primary Sjögren's Syndrome
The AMISS study will characterize the features of muscle disease in patients with primary Sjogren's syndrome (pSS).
- Trial name
- AMISS (NCT03126383)
- Where
- France
- Volunteers
- 54 people
- Sponsor
- University Hospital, Brest
ANCA-associated Vasculitis
Biocollection of Patients With ANCA Associated Vasculitis
As rare disease, vasculitis affects a small number of patients, the cohorts available in the literature are few and the pathophysiological mechanisms remain to be elucidated.
- Trial name
- ANCA (NCT05364892)
- Testing
- Blood samples (80 mL), Fecal samples, Urinary sample (20-40 mL)
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Sleep Disorders
Validation of a Method of Screening for Sleep Disorders in Children With Cerebral Palsy, Using Connected Tools
Cerebral palsy (CP) is the most common cause of child disability. Nearly 40% of PC children suffer from sleep disorders, which are not routinely screened.
- Trial name
- SOUTIEN-PC (NCT03915418)
- Testing
- Connected tools
- Where
- 6 sites in France
- Volunteers
- 140 people
- Sponsor
- University Hospital, Brest
Shock, Cardiac Output, Low
Comparison of Allows Measurement of Cardiac Output Between Clearsight System and Transpulmonary Thermodilution
Correlation study between the data provided by two measurement systems, trans- pulmonary thermodilution and ClearSight © (non invasive), to determine the interest in routine use (cardiac output, cardiac index, stroke volume and…
- Trial name
- CONDUCT (NCT02728791)
- Where
- France
- Volunteers
- 42 people
- Sponsor
- University Hospital, Brest
Systemic Lupus Erythematosus
Follow-up of the Systemic Lupus Erythematosus Cohort as Part of the Multidisciplinary Consultation at Brest CHRU
Systemic lupus erythematosus is a complex systemicautoimmune disease that can affect most organs of the human body. Although they are many recommendations on the diagnosis and managment of SLE, diagnosis and therapeutic managment…
- Trial name
- COLUPUS (NCT06551389)
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Brest
Cancer, Lung, Radiotherapy; Complications
Follow-up of Pulmonary Radiotoxicity for Bronchopulmonary Cancer.
assess the consequences of low doses of radiation delivered by the volumetric radiotherapy, on the respiratory capacity of patients treated for bronchopulmonary carcinoma, by a follow up of functional respiratory exploration.
- Trial name
- TEFRARC (NCT03931356)
- Testing
- Pulmonary function tests
- Where
- France
- Volunteers
- 39 people
- Sponsor
- University Hospital, Brest