Clinical trials: sponsored by University Hospital, Brest
Subarachnoid Hemorrhage, Pneumonia, Bacterial
Influence of Pneumonia on Delayed Cerebral Ischemia After Subarachnoid Hemorrhage . SAH-CIP (SubArrachnoid Hemorrhage - Cerebral Infarction Pneumonia)
Prognosis of subarachnoid hemorrhage (SAH) is scarce, indeed almost half patients die or become severely disable after SAH. Outcome is related to the severity of the initial bleeding and delayed cerebral infarction (DCI).
- Trial name
- SAH-CIP (NCT05094349)
- Where
- France
- Volunteers
- 224 people
- Sponsor
- University Hospital, Brest
HPV Vaccination, Pap Smear
Impact of HPV Vaccination to Catch up in the Emergence of Lesions of the Cervix
In France, the vaccination coverage observed for HPV vaccination is low for a full-scale regimen, and has been falling since 2010.
- Conditions
- HPV Vaccination, Pap Smear, Cervical Cancer, Catch-up Vaccination
- Trial name
- HPVAC (NCT03328013)
- Where
- France
- Volunteers
- 191 people
- Sponsor
- University Hospital, Brest
Cardiovascular Risk Factor
What Are the Factors for Maintaining and Stopping of Accompanying Citizens? Do Personality Traits of Accompanying Citizens Appear to Influence These Factors?
In 2017, cardiovascular diseases (CVDs) were the leading cause of death worldwide. Most cardiovascular diseases can be prevented by changing risk behaviors.
- Trial name
- SPICES_MIX (NCT05080517)
- Where
- France
- Volunteers
- 21 people
- Sponsor
- University Hospital, Brest
Prospective Study
Clinical and Radiological Evaluation of Two Mastoid Filling Products
to compare, the osseous density in the mastoid of two products used to obliterate the mastoid during surgery for cholesteatoma
- Trial name
- MASTOS (NCT05072678)
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Brest
Transplant; Complication, Failure
Evaluation of HEMO2Life® for Kidney Graft Preservation (OXYOP): 4 Years Follow-up
4 years follow-up of the oxyop study.
- Trial name
- OXYOP4 (NCT05050513)
- Where
- France
- Volunteers
- 116 people
- Sponsor
- University Hospital, Brest
Chronic Obstructive Pulmonary Disease
Intra- and Inter-evaluator Reproducibility of Upper Limb Strength Measures in Patients With COPD
According to the recommendations of French and international learned societies, respiratory rehabilitation is part of the care of patients with Chronic Obstructive Pulmonary Disease (COPD).
- Trial name
- FORMES (NCT04341753)
- Testing
- pulmonary rehabilitation
- Where
- France
- Volunteers
- 57 people
- Sponsor
- University Hospital, Brest
Pulmonary Diseases, Fever
Pneumocystis Primary Infection in Non-immunosuppressed Infants
To determine the prevalence of P. jirovecii in nasopharyngeal aspirations of neonates and infants hospitalized for symptomatic respiratory infection.
- Trial name
- CAPRI-PC (NCT03740646)
- Where
- France
- Volunteers
- 400 people
- Sponsor
- University Hospital, Brest
Giant Cell Arteritis
Comparison of 22Mhz and 18Mhz High-frequency Probes for the Ultrasound Study of Temporal Arteries in Patients Suspected of Having Giant Cell Arteritis
Evaluation of the structural features of temporal arteritis using two frequencies probes: 18 and 22Mhz.
- Trial name
- ECHORTON (NCT04204512)
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Brest
MDS, ALL
Optical Genome Mapping in Hematological Malignancies
Establish the diagnostic potential of optical genome mapping in patients with suspected hematologic cancer
- Conditions
- MDS, ALL, Other Hematologic Malignant Neoplasms
- Trial name
- CARTOGEN (NCT05009537)
- Where
- 4 sites in France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Brest
the Cement Augmented Screws of TFNA Nails
Use of Cemented TFNA Nail Augmentation in the Treatment of Trochanterian Rock Fractures
Intramedullary nailing is the standard treatment of trochanteric fractures. Mechanical failure such as cut-out and cut-through are associated with high rates of revision surgery, functional impairment and mortality.
- Trial name
- TFNA (NCT04993053)
- Where
- France
- Volunteers
- 61 people
- Sponsor
- University Hospital, Brest
Foramen Ovale, Patent
Risk of Ischaemic Stroke After Pulmonary Embolism in Patients With and Without Patent Foramen Ovale
stroke's risk is increased in patients with pulmonary embolism and PFO compared to patients without PFO. Does this increased risk persist years after pulmonary embolism ?
- Trial name
- EPIC-FOPCohort (NCT04987008)
- Where
- 3 sites in France
- Volunteers
- 53 people
- Sponsor
- University Hospital, Brest
Prostatic Neoplasms, Recurrence
PSMA PET/CT for Biochemical Recurrence Detection in Patients With Prostate Cancer
The aim of this study is to evaluate PSMA-PET for the detection of occult biological recurrence in patients with prostatic cancer referred to the Brest University Hospital.
- Trial name
- RB-PSMA (NCT04983459)
- Where
- France
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Endometrial Cancer
Pelvic Sentinel Node Detection Using Indocyanine Green Learning Curve
According to ESGO-ESTRO-ESMO guidelines, pelvic Sentinel lymph node detection is suitable for lymph node staging in endometrial carcinoma of the uteri.
- Trial name
- ENDO-GREEN (NCT04958278)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Brest
SARS-CoV2 Infection
Evaluation of the Sofia SARS Antigen FIA Assay for COVID-19
Evaluating the performance of the Sofia SARS Antigen FIA
- Trial name
- ESADEC (NCT04953091)
- Where
- 2 sites in France
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Knee Arthroplasty
Multimodal Modeling of the Knee Joint
The trial will contribute to the development of an innovative algorithm that aims to simplify and improve preoperative knee surgical decision.
- Trial name
- KneeMod (NCT04179812)
- Where
- France
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Chronic Pruritus
Causes of Chronic Pruritus
The aim of this study is to include all patients followed between 2008 and 2018 in order to analyze the etiologie of the chronic pruritus
- Trial name
- PRURISINE (NCT04949893)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Brest
Prosthetic Joint Infection, Staphylococcus
Clindamycin in Prosthetic Joint Infections Caused by Staphylococcus (CISTA)
The alternatives to the combination of Fluoroquinolone and Rifampicin in prosthetic joint infections (PJI) caused by staphylococcus are currently unclear.
- Trial name
- CISTA (NCT04946500)
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Cystic Fibrosis
Epidemiology of Anaerobic Bacteria in Cystic Fibrosis Patients: Descriptive and Non-interventional Study
Recently, the respiratory microbiota characterisation of a Cystic Fibrosis (CF) patients' cohort has highlighted the potential role of anaerobes, and specially species belonging to the genus Porphyromonas, in the first P.
- Trial name
- ANA-MUCO (NCT04879381)
- Testing
- Sputum samples
- Where
- 2 sites in France
- Volunteers
- 101 people
- Sponsor
- University Hospital, Brest
Aneurysm, 4D CT Scan
Pulsatility Aneurysmal Evaluation Process by Cerebral Dynamic CTA (Computed Tomography Angiography)
Intracranial aneurysm are frequent with a prevalence estimated over 2-5% in the general population. These are focal dilatations occuring in the cerebral vessels. They usually remain silent until complications occur.
- Trial name
- PULSAN (NCT03535181)
- Where
- France
- Volunteers
- 11 people
- Sponsor
- University Hospital, Brest
Lung Cancer
Immunological Markers Predictive of Response and Toxicity to Checkpoint Inhibitors in Non-small Cell Lung Cancer
A prospective, observational, single-center study to determine the proportion of patients who have or will develop changes in biological markers of immunity during immunotherapy treatment.
- Trial name
- IMMUNO-PREDICT (NCT04918836)
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Brest