Clinical trials: sponsored by University Hospital, Brest
Arrest Cardio Respiratory
Free Iron and Out of Hospital Cardiac Arrest
Out of hospital cardiac arrest is associated with a poor prognosis. The aim of this study is to provide a better understanding of perturbations of iron metabolism after cardiac arrest and to analyze the impact on clinical…
- Trial name
- DESFER (NCT03491670)
- Where
- France
- Volunteers
- 25 people
- Sponsor
- University Hospital, Brest
High Intellectual Potential, Children
Study of Gesture and Executive Functions in Children With High Intellectual Potential
The main objective of this study is to determine whether children with high intellectual potential have gestural and / or executive difficulties compared to control children.
- Trial name
- MOHPI (NCT03128125)
- Testing
- clinical examination in neurology, neuropsychological examination, anamnestic elements
- Where
- France
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Ovarian Neoplasm
Survival Data and Characteristics of Finisterian Patients Treated With PARP Inhibitors for Ovarian Cancer Between 2014 and 2019.
Ovarian cancer is a relatively uncommon but serious disease. It ranks 10th for female cancers, 5th for mortality, and its origin is still imperfectly known.
- Trial name
- BREIZH-PARPi (NCT04573933)
- Where
- 4 sites in France
- Volunteers
- 54 people
- Sponsor
- University Hospital, Brest
Acute Gastroenteritis, Dehydration
Continuous Enteral Rehydration by Nasogastric Tube With ORS in Children With Acute Gastroenteritis
When oral rehydration is impossible, enteral rehydration via the nasogastric route has been the recommended method of rehydration since 2008 by ESPGHAN ( European Society for Paediatric Gastroenterology Hepatology and Nutrition…
- Trial name
- GEA (NCT04555200)
- Where
- France
- Volunteers
- 88 people
- Sponsor
- University Hospital, Brest
Crystal-Induced Arthritis
Biotherapy Treatment on Features of Microcrystalline Polyarthritis
The study will involve adult patient who had received any biologic agent for microcrystalline disease in western France (Tours, Le Mans, Orléans, Angers, Rennes, Poitiers et Brest) between 01/01/2010 and 31/12/2018.
- Trial name
- FUMBLE (NCT04005625)
- Where
- France
- Volunteers
- 46 people
- Sponsor
- University Hospital, Brest
Lateral Amyotrophic Sclerosis, Venous Thrombo-embolic Desease
Venous Disease Thromboembolic and Amyotrophic Lateral Sclerosis
Venous thrombo-embolic (VTE) rates could be high in patients with amyotrophic lateral sclerosis (ALS). Indeed, the rate of VTE in this specific population could be 7-fold higher in this population.
- Trial name
- TESLA (NCT04446325)
- Where
- France
- Volunteers
- 227 people
- Sponsor
- University Hospital, Brest
Endocrine System Diseases, Osteoporosis
Endocrine, Bone And Metabolic Disorders In Adults After Allogeneic Stem-cell Transplant
Allogeneic hematopoietic stem cell transplantations (allo-HSCT) is often indicated in malignant hematologic diseases. Conditioning regimens, used to reduce the tumor burden and to prevent transplant rejection, are based on…
- Conditions
- Endocrine System Diseases, Osteoporosis, Metabolic Syndrome, Adrenal Insufficiency
- Trial name
- ENDOCALLOGREFF (NCT04488432)
- Where
- France
- Volunteers
- 45 people
- Sponsor
- University Hospital, Brest
Lung Cancer
Prediction of Esophageal and Lung Toxicities After Radiation (Chemo) Therapy
(Chemo)-radiotherapy is the gold standard therapeutic treatment for patients with locally advanced lung cancer non accessible or ineligible for surgery.
- Trial name
- PTOP-RT (NCT04545658)
- Where
- France
- Volunteers
- 167 people
- Sponsor
- University Hospital, Brest
Placental Abruption, Placenta Diseases
Study on Retroplacental Hematomas in Finistère
Cases with placental abruption will be identified by interrogation of two databases of Brest University Hospital between January 2013 and December 2018. First trimester PAPPA and bhCG levels will be recorded.
- Trial name
- HEMOPLACENTA (NCT04168606)
- Where
- France
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Hand Dermatoses
Hand Dermatitis in the Care and Hospital Staff
Study of the prevalence and risk factors of occupational dermatitis in the hands of caregivers and hospital staff of the Brest CHRU.
- Trial name
- MANUS-PRO (NCT04136574)
- Where
- France
- Volunteers
- 1,138 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Pruritus, Monoclonal Gammopathy
Frequency and Characteristics of Pruritus in Patients With Monoclonal Gammopathy
Pruritus is most often secondary to dermatitis but can also occur without skin lesions, it is called pruritus sine materia. The causes of pruritus sine materia are various: haematological (myeloproliferative neoplasia ...)…
- Trial name
- PRURIGAMMA (NCT03832140)
- Where
- France
- Volunteers
- 281 people
- Sponsor
- University Hospital, Brest
Brain Metastases
Dosimetric Validation of Scans Generated by GAN From Pre-therapeutic MRI in Stereotactic Cerebral Radiotherapy
Stereotactic radiotherapy (SRT) is being widely accepted as a treatment of choice for patients with a small number of brain metastases and an acceptable size, allowing a better target dose conformity resulting in high local…
- Trial name
- SBRT-IRM (NCT04525053)
- Where
- France
- Volunteers
- 184 people
- Sponsor
- University Hospital, Brest
Asthma in Children, Asthma Attack
Child Asthma : What Parents Attitude During an Asthma Attack at Home Before Consulting the Pediatric Emergencies
prospective multicenter observational study. Parents whose children meet the inclusion criteria complete a questionnaire assessing the child's follow-up, the management of the current asthma attack, and the treatment provided at…
- Conditions
- Asthma in Children, Asthma Attack, Therapeutic Adherence
- Trial name
- ASPECT (NCT03967873)
- Where
- 2 sites in France
- Volunteers
- 350 people
- Sponsor
- University Hospital, Brest
MECP2-Related Severe Neonatal Encephalopathy, Dysautonomia
Dysautonomic Phenotype in Male Patients With MECP2 Mutation
Dysautonomic signs are well known among girls with a Rett Syndrom. Rett syndrom is caused by a MECP2 mutation in 95% of cases. We want to search dysautonomic signs among boys with a MECP2 mutations because they are less studied…
- Conditions
- MECP2-Related Severe Neonatal Encephalopathy, Dysautonomia, Masculinity
- Trial name
- MECP2BOYS (NCT04502199)
- Testing
- non interventional study
- Where
- 7 sites in France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Brest
Stroke, Critically Ill
Study of Prognostic Factors in Patients Admitted to ICU for Stroke
Outcome of stroke patients admitted to the intensive care unit the intensive care unit (ICU) is poor and haemorrhagic stroke, fixed dilated pupil(s) and GCS <10 are associated with increased mortality and poor functional outcome.
- Trial name
- REAVC (NCT04434287)
- Where
- France
- Volunteers
- 204 people
- Sponsor
- University Hospital, Brest
Surgery--Complications
Incidence of Rhinological Morbidities During Endonasal Pituitary Surgery, With or Without Nasoseptal Flap
Determine and compare prospectively the incidence of rhinological adverse events during pituitary surgery with or without nasoseptal flap
- Trial name
- HLNS (NCT04493801)
- Where
- France
- Volunteers
- 160 people
- Sponsor
- University Hospital, Brest
Alcohol Abuse
Perception of the Risks of Alcohol and Individual Vulnerabilities in Young Adults
Alcohol use is the second leading cause of preventable death after smoking. The Evin law was built in 1991 with the goal of reducing exposure to alcohol marketing among the youngest.
- Trial name
- DEPREV (NCT03876132)
- Where
- France
- Volunteers
- 23 people
- Sponsor
- University Hospital, Brest
Handball Players
Determination of Normal Values for the Star Excursion Balance Test (SEBT) in Handball Players
the aim of this study is to determine normal values for SEBT in young national or international handball women players for determining specific level for SEBT to predict risk of injury
- Trial name
- SEBTHAND (NCT03797430)
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Pulmonary Disease
Cardio-Respiratory Response of a Training Session Versus an Adapted Physical Activity Session
the aim of this study is to show that training session with nintendo WII requires the same cardiorespiratory demand than training session on ergocycle or treadmill, traditionally used in pulmonary rehabilitation program.
- Trial name
- WIIRR (NCT03793504)
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Brest
Copd
Effect of Pulmonary Rehabilitation on Fear of Falling in COPD Patients
The aim of this study is to measure the impact of pulmonary rehabilitation program on fear of falling in COPD patients
- Trial name
- PARACHUTE (NCT03793452)
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Brest