Clinical trials: sponsored by University Hospital, Brest
Non Small Cell Lung Cancer Metastatic, Treatment Adverse Effect
Thyroid Dysfunction and Nivolumab Reponse in NSCLC
This is an observational, retrospective and monocentric study, conducted at the university Hospital of Brest The primary objective is to assess the association between the occurrence of thyroid dysfunction in patients treated…
- Conditions
- Non Small Cell Lung Cancer Metastatic, Treatment Adverse Effect, Thyroid Dysfunction, Immune Checkpoint Inhibitor
- Trial name
- THYRONIVO (NCT04470440)
- Where
- France
- Volunteers
- 134 people
- Sponsor
- University Hospital, Brest
Ovarian Hyperstimulation Syndrome, Cardiovascular Diseases
Medical Assistance for the Procreation and Risk of Thrombosis.
This study aims at evaluating clincal practice regarding prevention of arterial and venous thrombosis following ovarian stimulation.
- Conditions
- Ovarian Hyperstimulation Syndrome, Cardiovascular Diseases, Embolism and Thrombosis
- Trial name
- AMPERT (NCT02610608)
- Testing
- ovarian stimulation
- Where
- 9 sites in France
- Volunteers
- 129 people
- Sponsor
- University Hospital, Brest
Malignant Lymphoma, Relapsed Non Hodgkin Lymphoma
Interest of a Systematic One-year Monitoring by 18F-FDG PET-CT
In the study, we aimed to characterize the role of FDG PET/CT surveillance at 12 months of malignant lymphoma in asymptomatic patients after a first complete remission and to define a rational follow-up strategy.
- Conditions
- Malignant Lymphoma, Relapsed Non Hodgkin Lymphoma, Relapsed Hodgkin's Disease, Adult, Diagnostic Imaging
- Trial name
- LYMPHOTEP1 (NCT04464590)
- Volunteers
- 100 people
- Sponsor
- University Hospital, Brest
Pelvic Pain
Assessment of Pain of Pelvic Congestion Syndrome Treated by Coils Embolization
Summary: Main Objective: to evaluate the efficacy of pelvic gonadal vein embolization with coils in treatment of pelvic congestion syndrome Methods: retrospective study included 25 patients in the University hospital of Brest.
- Trial name
- SCVPC (NCT04461860)
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Brest
Psoriasis
Work Stress and Impact of Pruritus on Quality of Life
Work stress and pruritus: imbalance of effort balance reward in patients with psoriasis.
- Trial name
- PRUERI (NCT04316533)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Brest
Renal Transplantation
Comparison Thymoglobulin® and Grafalon®
This is a prospective, multicenter, observational, non -interventional study with comparison with an historical cohort Investigators will compare the efficacy and safety of Thymoglobulin (Sanofi-Aventis) versus Grafalon (Neovii…
- Trial name
- THYGRET (NCT03996278)
- Testing
- Grafalon
- Where
- 13 sites in France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Brest
Juvenile Idiopathic Arthritis, COVID 19
Drug Management of Juvenile Idiopathic Arthritis in Covid-19 Context : Impact on Therapeutical Managment
The current situation of Sars-Cov-2 pandemic generates fears in the general population. Among patients receiving long-term immunomodulatory drugs, especially in the context of auto-immune diseases, there may be legitimates…
- Conditions
- Juvenile Idiopathic Arthritis, COVID 19, Treatment
- Trial name
- RHUMAJICOVID (NCT04407923)
- Where
- 8 sites in France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Brest
Identify Emerging Health Challenges for Children With Motor Disabilities and Their Parents Facing the COVID-19 Pandemic
National Survey on the Lockdown of Children With Disabilities
During the COVID-19 pandemic, lockdown measures were established in France affecting the life course of children with disabilities.
- Trial name
- ECHO (NCT04395833)
- Where
- France
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Pruritus
Pruritus and Melanoma and Cutaneous Carcinomas Treated With Immunotherapy
Immune checkpoint inhibitors (ICIs) are commonly used in the therapeutic arsenal of metastatic melanoma, Merkel cell carcinoma and cutaneous squamous cell carcinoma, thanks to their inhibiting effects on cytotoxic…
- Trial name
- PRURICHECKPOIN (NCT04365244)
- Where
- 2 sites in France
- Volunteers
- 181 people
- Sponsor
- University Hospital, Brest
Occupational Stress
Experience of Hospital Students in the Odontology Department
During their studies, the dental students of Brest (France) learn their future profession by working in the Dental University Hospital, from the fourth academic year.
- Trial name
- EQUAVECU (NCT04364100)
- Where
- France
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Horton Disease
Velocimetric Study of Temporal Arteries in Patients With Horton Disease Using Scan-Doppler
The use of ultrasonography in detecting giant cell arteritis ( GCA) is emerging. Currently, temporal biopsy is the gold standard to diagnose GCA but studies have shown the interest to use B mode ultrasonography.
- Trial name
- VELHOR (NCT03360162)
- Where
- France
- Volunteers
- 46 people
- Sponsor
- University Hospital, Brest
Children Sedation
Comparison of Chlorpromazine or Pentobarbital Premedications for Pediatric Imaging Procedures
Sedation is often required for pediatric medical imaging procedures to ensure compliance and quality images. Recommendations exist regarding pediatric sedation, but there are currently no guidelines regarding the choice of the…
- Trial name
- PREIMAPED (NCT04350528)
- Testing
- Chlorpromazine or Pentobarbital
- Where
- France
- Volunteers
- 254 people
- Sponsor
- University Hospital, Brest
Chronic Low Back Pain
Robot Coach of Chronic Low Back Pain Patient
The objective of KERAAL technological project is to create a new intelligent robot which allows a humanoid robot to record then to show and to follow the progress of rehabilitation sessions proposed by a physiotherapist to a…
- Trial name
- RCOOL (NCT03260738)
- Testing
- Rehabilitation program with Poppy robot, Usual rehabilitation program
- Where
- 2 sites in France
- Volunteers
- 31 people
- Sponsor
- University Hospital, Brest
Patents With Normal VQ/SPECT
Normal Ventilatory and Perfusion Pulmonary Function in TEMP
Ventilation - perfusion SPECT is attractive for lung function assessement. Unfortunately, it is very difficult to delineate normal to abnormal areas because of physiological uptake heterogeneity.
- Trial name
- 3DSPECSTAT (NCT04332406)
- Where
- France
- Volunteers
- 96 people
- Sponsor
- University Hospital, Brest
ACL Injury
Evaluation of Clinical and Biomechanical Correlation During Return to Sport After Anterior Cruciate Ligament Injury
Comparison of two groups of subjets (ACL injury who return to sport) and control group non-injured about clinical and biomechanical data : clinical test functional test motion analysis of 2 sport exercises tibial translation…
- Trial name
- REPILOG (NCT02686723)
- Testing
- Clinical and biomechanical evaluations
- Where
- France
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Medical Termination of Pregnancy
Medical Termination of Pregnancy : Evaluation of Patients' Practices and Feelings in Brest Hospital
This study evaluate the feelings of patients about a medical termination of pregnancy that they experienced in Brest Hospital. Patients responded to an online questionnaire assessing their feelings at each stage of the medical…
- Trial name
- IMGEPR (NCT04294212)
- Where
- France
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Wrist Arthritis, Survival
Total Wrist Denervation: Survival Study and Functional Outcomes
The purpose of the study is to evaluate the long-term effectiveness of total wrist denervation on pain by assessing the surgery survival.
- Trial name
- DTDPESERF (NCT03977389)
- Testing
- Total wrist denervation
- Where
- France
- Volunteers
- 63 people
- Sponsor
- University Hospital, Brest
Prematurity, Parenting
Study of the Quality of Sleep of Parents of Premature Children Compared to Parents of Full-term Children
This study evaluate the incidence of sleep disorders in parents of premature children hospitalized in unit care of neonatalogy or intensive unit care of neonatalogy, compared to parents of full-term child in maternity.
- Conditions
- Prematurity, Parenting, Sleep Deprivation
- Trial name
- SLEEP-PP (NCT03693651)
- Where
- France
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Metabolic Myopathies, Exercise Test
Metabolic Exercise Testing
Exertional symptoms are the hallmarks of metabolic myopathies, supporting the concept of using functional tests when this diagnosis is suspected.
- Conditions
- Metabolic Myopathies, Exercise Test, Myalgia
- Trial name
- RANNOU (NCT02362685)
- Testing
- functional test, matching genotype with phenotype
- Where
- France
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Aspergillosis, Influenza
Invasive Pulmonary Aspergillosis and Severe Influenza
Invasive pulmonary aspergillosis (IPA) has been reported in critically ill patients with influenza infection with a highly variable incidence between 1 to 21%.
- Conditions
- Aspergillosis, Influenza, Critical Illness
- Trial name
- ASPERGIGRIPP (NCT04232956)
- Where
- 4 sites in France
- Volunteers
- 478 people
- Sponsor
- University Hospital, Brest