Clinical trials: sponsored by University Hospital, Brest
Breastfeeding Mothers of Infants Hospitalized
The "Pooling" Expressed Breast Milk: A Method for Improving the Nutritional Intake of Premature Infants
The investigators compared a pooled mother's expressed breastmilk for 24 hours with individual pump session collection of milk to provide a more consistent caloric product without increasing bacterial contamination.
- Trial name
- POOL-BM (NCT02994823)
- Where
- France
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Positron Emission Tomography, Glioma
18F-Fluoro-Ethyl-Tyrosine (FET) Positron Emission Tomography (PET) and Grading Glioma
Role of 18F-FET PET for grading gliomas according to 2016 WHO classification: value of quantitative and qualitative data obtained by 18F-FET PET for differentiating low grade glioma (WHO II) versus high grade gliomas (WHO III and…
- Trial name
- GLIOFET (NCT04001257)
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Brest
Primary Dysmenorrhea
Sense of Coherence and Primary Dysmenorrhea in High School Girls in Finistere, France
This study evaluates the relation between sens of coherence and primary dysmenorrhea. Aself-questionnaire is completed by a sample of girls aged between 14 and 19, schooled in Finistère (France).
- Trial name
- DysM et SOC (NCT04083131)
- Where
- 6 sites in France
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Primary sjögren's Syndrome
Ultrasound Abnormalities of the Salivary Glands in Primary Sjögren's Syndrome According to the Duration of the Disease
Salivary gland ultrasonography is identified as a valuable diagnostic tool and potential criteria item for disease classification of sjögren's syndrome and evaluate evolution of parenchyma.
- Trial name
- MASAÏ (NCT04212572)
- Where
- 3 sites in France
- Volunteers
- 242 people
- Sponsor
- University Hospital, Brest
Metastatic Bronchopulmonary Cancer
Development of a Model to Predict the Risk of Venous Thromboembolic Events in Patients With Metastatic Bronchopulmonary Cancer
Venous thrombo-embolism (VTE) is a frequent and serious complication of cancer. However, predictive tools for VTE in cancer patients is lacking.
- Trial name
- LUCAAT (NCT04196790)
- Where
- 3 sites in France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Brest
High Flow Nasal, Time of Flight Camera
Evaluation of Lung Volume Under Nasal High Flow With a Time of Flight Camera
The effectiveness of Nasal High Flow therapy (NHF), in comparison with conventional oxygen therapy, is based on Positive Expiratory Pressure (PEP) and washout of dead space.
- Conditions
- High Flow Nasal, Time of Flight Camera, Lung Volume, Healthy Volunteers
- Trial name
- CamOpt (NCT04096183)
- Testing
- Ventilation of healthy volunteers
- Where
- France
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Small Fiber Neuropathy
Causes Associated With Small Fiber Neuropathy (SFN).
Small fiber neuropathy (SFN) is an injury of cutaneous nerve fibers, mainly by a decrease in their density within the cutaneous tissue.
- Trial name
- EtioNPF (NCT04170205)
- Where
- France
- Volunteers
- 450 people
- Sponsor
- University Hospital, Brest
Osteoradionecrosis of Jaw
Osteoradionecrosis and PENTOCLO Protocol: Retrospective Study
osteoradionecrosis (ORN) affects up to 30% of irradiated patients and can occur up to several decades after stopping treatment. Differents therapeutics exist but there is no consensus concerning the management of the maxillary…
- Trial name
- OPEN (NCT04097847)
- Testing
- Pentoxifylline-Tocopherol-Clodronate
- Where
- France
- Volunteers
- 96 people
- Sponsor
- University Hospital, Brest
Endotracheal Intubation, Deep Sedation
Inhaled Sedation Using the Anesthetic-conserving Device ( ANACONDA) in Prehospital Emergency Medecine.
Achieving the optimal sedation level for patient management is not always possible using our standard intravenous medications in Pre-hospital Emergency medicine.
- Trial name
- ANACONDA (NCT04141267)
- Where
- France
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Adolescent Development, Post Traumatic Stress Disorder
Teenagers After London Terrorist Attack
Context: Since March 2012, several terrorist attacks have been perpetrated in France (Toulouse, Montauban, Paris, Nice ...). In March 2017, 53 french teenagers were victims in a terrorist attack in London (Westminster Bridge).
- Conditions
- Adolescent Development, Post Traumatic Stress Disorder, Terrorism
- Trial name
- AVAL (NCT03493243)
- Testing
- Questionnaires
- Where
- 2 sites in France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Brest
Venous Thromboembolism
Thrombus Elastography in Venous Thrombo-Embolism.
Venous Thrombo-Embolic Disease (VTED) is a serious and common ailment, defined by the growth of a clot - or thrombus - in a vein, and/or as the migration of this thrombus to a pulmonary artery.
- Trial name
- TEVTE (NCT04130048)
- Testing
- Ultrasound Elastography
- Where
- France
- Volunteers
- 45 people
- Sponsor
- University Hospital, Brest
Meningioma
Meningiomas and Treatment With CYPROTERONE ACETATE or Progestin
Investigators observe an increase risk of meningioma in patient treated by CYPROTERONE ACETATE or other form of progestin. Investigatorsdiscribe caractéristics of meningioma and treatement of the patients follow up in CHRU of…
- Trial name
- MAP (NCT04109404)
- Where
- France
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Critical Care, Medication
Stopping Cardiovascular Treatments and Mortality in a MICU
Cardiovascular treatments should not be interrupted following hospital admission, in order to decrease patients' morbidity. However, following ICU admission, such treatments are frequently interrupted and/or modified.
- Conditions
- Critical Care, Medication, Cardiovascular Diseases, Outcome, Fatal
- Trial name
- TRAM (NCT04121429)
- Testing
- Observation
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Brest
Severe Brain Injury
Study of PbiO2 Variation by Body Temperature and Capnia in Severe Head Trauma Patients Treated With Targeted Temperature Control
Serious head trauma is a common and pathology and responsible of high morbidity and mortality. The major challenge, from the very first hours, is to limit cerebral ischemia by controlling secondary brain injury factors.
- Trial name
- TODAY (NCT04109430)
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Brest
Anemia, Surgery
Anemia and Red Blood Cells Transfusion in Oncological Surgery
Oncologic patients experience anemia and anemia is associated with poor prognosis. Transfusion is associated with adverse events, and equipoise remains on the optimal transfusion strategy in oncologic patients in surgical…
- Conditions
- Anemia, Surgery, Oncology
- Trial name
- IMPACT (NCT04101240)
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Brest
Prostatic Adenocarcinoma
Prediction of the Risk of Biochemical Relapse After Radical Prostatectomy for Prostate Cancer Using Radomics on Pre-therapeutic MRI
With 50% of post-operative biochemical failure, efficient predictive models are needed to guide post-operative management. Radiomic features are quantitative features extracted from medical imaging, supposed to be correlated with…
- Trial name
- PREBOP (NCT04063800)
- Where
- 2 sites in France
- Volunteers
- 195 people
- Sponsor
- University Hospital, Brest
Pruritus
Study Evaluating the Benefit of Music Therapy on Pruritus in Patients With Pruritic Dermatitis
Many clinical studies have shown the benefit of music therapy in various pathologies, including pain, and it is now established that the latter has a complementary therapeutic interest.
- Trial name
- PRURI-MUSIC (NCT03701971)
- Testing
- evaluation of the intensity of pruritus
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Brest
Intubation
A Systematic Echography During Intubation Procedure to Predict Cardiovascular Collapse
In the operating room, most intubation procedures (IP) are scheduled and performed on hemodynamically stable patients. In the ICU, IP is frequently performed in emergent patients, because of unstable hemodynamics and/or acute…
- Trial name
- EPIC (NCT03184207)
- Where
- 3 sites in France
- Volunteers
- 70 people
- Sponsor
- University Hospital, Brest
Urinary Incontinence, Stress
Stress Urinary Incontinence of Sporting Teenager
Physical activity and sport are beneficial to the cardiovascular system, the musculoskeletal system and many chronic pathologies. The High Authority of Health (HAS) recommends a regular practice.
- Trial name
- INCREASE (NCT03309397)
- Where
- France
- Volunteers
- 103 people
- Sponsor
- University Hospital, Brest
Measure of the X-ray Dose
Comparative Study of Calculating the X-ray Dose to the Skin of the Patient Exposed
The main objective is to estimate the precision of the calculation by the software DoseMap ® towards the in vivo measure by gafchromic movie.
- Trial name
- DOSEMAP (NCT04048694)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Brest