Clinical trials: sponsored by University Hospital, Brest
Stroke Basal Ganglia
Emotions Analysis in Patients With Chronic Phase of Stroke Basal Ganglia
Compare the emotional experience of patients with focal lesions of the basal ganglia by ischemic or hemorrhagic damage and healthy participants.
- Trial name
- KALISS (NCT02884882)
- Testing
- Emotional induction
- Where
- France
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Hypophosphatemia, Infection
Hypophosphatemia as a Predictor in Surgical Resuscitation Sepsis
Retrospective study in the surgical intensive care unit of the Brest Teaching Hospital (France) during a 6-months period (January 2015 -May 2015) to study the independent association between hypophosphatemia and 28-day infection.
- Trial name
- NCT03740802
- Where
- France
- Volunteers
- 264 people
- Sponsor
- University Hospital, Brest
Neuroendocrine Tumors
Neuroendocrine Tumors of Old Patients in the West of France
Neuroendocrine cancer remains a poorly known entity. Comprehensive treatment is multidisciplinary involving surgery, radiological and nuclear medicine, and medical.
- Trial name
- TANGO (NCT03749681)
- Where
- France
- Volunteers
- 306 people
- Sponsor
- University Hospital, Brest
Chest Pain, Dyspnea
Diagnostic Reasoning and Sense of Alarm at Dyspnoea and / or Chest Pain
Dyspnea and chest pain represent 1.5% of general practice consultations. They may be a sign of many diseases, potentially serious. The concept of Gut Feelings brings a sense of alarm and reinsurance.
- Trial name
- RaisDiag (NCT02932982)
- Where
- 11 sites in France
- Volunteers
- 241 people
- Sponsor
- University Hospital, Brest
COPD
Screening for COPD in Primary Care: a Synergistic Approach - Dentists - Pharmacists -Physiotherapists - Nurses - Physicians
A recent French study conducted in the general population in the north, using more than 12,000 people randomly drawn from the electoral lists, shows a prevalence of nearly 15% of an obstructive spirometric function disorder; The…
- Trial name
- UNANIME (NCT03104348)
- Testing
- COPD screening
- Where
- 2 sites in France
- Volunteers
- 179 people
- Sponsor
- University Hospital, Brest
Oncology
Modeling of the Response to Hypofractionated Stereotactic Pulmonary Irradiation
Identify 18-Fluorodeoxyglucose (18F-FDG) positron emission tomography-computed tomography (PET-CT) parameters predictive of tumor response and local control
- Trial name
- MUMOFRAT (NCT03175861)
- Testing
- Stereotactic radiotherapy
- Where
- 4 sites in France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Brest
Cerebral Palsy
Analgesia and Physiotherapy in Children With Cerebral Palsy (ANTALKINECP)
SPARCLE 1 and 2 studies followed a cohort of 818 children with cerebral palsy (CP) between 8 and 12 (SPARCLE 1) and 13 and 18 years old (SPARCLE 2) interviewed at home.
- Trial name
- ANTALKINECP (NCT02839785)
- Testing
- Ibuprofen
- Where
- 3 sites in France
- Volunteers
- 3 people
- Sponsor
- University Hospital, Brest
Cystic Fibrosis, Respiratory Infection
Sputum Validation for the Molecular Diagnosis of Respiratory Viral Infections in Cystic Fibrosis
The aim of this pilot study is to demonstrate the feasibility of viral biomolecular diagnosis in sputum compared to nasopharyngeal swab in cystic fibrosis acute respiratory infection.
- Trial name
- EXPIRE (NCT03684759)
- Where
- 3 sites in France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Brest
Primary Sjögren's Syndrome (pSS)
Diagnostic Suspicion of Primitive Syndrome Sjögren's : Brest Cohort
This study aims to evaluate the diagnosis performance of several item used for the classification, the diagnosis and the prognostic of pSS (primary Sjogren syndrome)
- Trial name
- DIApSS (NCT03681964)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Brest
Multiple Myeloma, Non-hodgkin Lymphoma
Use of Zarzio® in Post-autologous Stem Cell Transplantation Procedure
There are limited data concerning the use of biosimilars of filgrastim in autologous stem cell transplantation (ASCT). This study aimed to evaluate G-CSF efficiency and safety (based on haemograms, transfusion needs and…
- Conditions
- Multiple Myeloma, Non-hodgkin Lymphoma, Hodgkin Lymphoma
- Trial name
- ZAPA (NCT03323541)
- Testing
- Filgrastim Prefilled Syringe [Zarzio®]
- Volunteers
- 62 people
- Sponsor
- University Hospital, Brest
Corpus Callosum Malformation, Prenatal Disorder
Frequency and Type of Genetic Abnormalities Found in Antenatal Corpus Callosum Malformation
Corpus callosum malformation (CCM) is the most frequently detected cerebral defect diagnosed in the prenatal setting. The most common CCM is corpus callosum agenesis (CCA) which is found in 2 to 3% of patients presenting with…
- Trial name
- AGMCC1318 (NCT03680651)
- Where
- France
- Volunteers
- 275 people
- Sponsor
- University Hospital, Brest
Myelofibrosis
Interferon-pegyle α2a Efficiency and Tolerance in Myelofibrosis
Patients who carried primary or secondary myelofibrosis from Philadelphia negative MPNs (PMF/SMF) and who are treated or are about to be treated with pegylated-interferon (mostly α2a) are eligible to this prospective study.
- Trial name
- PEG-MF (NCT02910258)
- Where
- 12 sites in France
- Volunteers
- 62 people
- Sponsor
- University Hospital, Brest
Polycythemia Vera, Essential Thrombocythemia
Drug Observance and Side Effects of Cytoreductive Drugs in PV and ET Patients
Patients treated with oral or sub-cutaneous drugs for polycythemia vera or essential thrombocythemia completed an unique paper questionnaire in order to describe their observance, the side effects and their own appreciation of…
- Trial name
- OUEST (NCT02893410)
- Where
- France
- Volunteers
- 286 people
- Sponsor
- University Hospital, Brest
Miscarriage in Second Trimester
Pregnancy Loss Between 15 and 22 Weeks SA Within the Network of Perinatal Pérriodof Western Brittany : Case Control Study PILOT STUDY CA
The etiologies and some risk factors for pregnancy loss in the 2nd trimester are described in the literature. However, there are some risk factors that are not studied.
- Trial name
- PEGREP (NCT03668743)
- Where
- 2 sites in France
- Volunteers
- 202 people
- Sponsor
- University Hospital, Brest
Pulmonary Embolism
Time Trend Analysis of PE Diagnosis With SPECT V/Q: a Single Institution Observational Study
Following the implementation of SPECT V/Q imaging for PE diagnosis, the investigators previously conducted an observational study over the period 2011-2013 that showed the safety of a diagnostic management based on SPECT V/Q to…
- Trial name
- TOMOBS (NCT03657992)
- Where
- France
- Volunteers
- 2,000 people
- Sponsor
- University Hospital, Brest
Urinary Tract Infections, Resistant Infection
Optimization Management Study of Community Urinary Tract Infections Spectrum
Urinary tract infections are the second most common community-acquired infections. Even if extended spectrum β-lactamase-producing Enterobacteriaceae (ESBLE) cause fewer urinary tract infections, their proportion is increasing.
- Conditions
- Urinary Tract Infections, Resistant Infection, Community-Acquired Infections, Beta Lactam Resistant Bacterial Infection
- Trial name
- OPTICUR-EBLSE (NCT03655548)
- Volunteers
- 108 people
- Sponsor
- University Hospital, Brest
Opiate Dependence, Chronic Pain
Medicinal Dependence and Chronic Pain: Addictive Evaluation in CETD
prescription opioid misuse in chronic pain is a growing public health concern. few studies got interested in prevalence of misuse and of opiate use disorder in a population of patients with a non cancer chronic pain.
- Trial name
- DEMDOU (NCT03635346)
- Where
- France
- Volunteers
- 128 people
- Sponsor
- University Hospital, Brest
Radius; Fracture, Lower or Distal End, Tendon Injury - Upper Limb
Screw Lengths in Radius Volar Plates
Background Fractures of the distal radius are among the most common. Major complications, including irritation and rupture of the extensor tendons, may occur if epiphyseal screws of inappropriate length are used.
- Conditions
- Radius; Fracture, Lower or Distal End, Tendon Injury - Upper Limb, Fracture Fixation, Internal
- Trial name
- PESLDRF (NCT03634865)
- Where
- France
- Volunteers
- 41 people
- Sponsor
- University Hospital, Brest
Prostate Cancer
Functional Medical Imaging Quantization in Prostate Cancer
Prostate cancer is the most common cancer in men over 50 years old and the third leading cause of cancer death. Because of the variety of prostate cancers, different treatments exist.
- Trial name
- QUIP (NCT03376360)
- Where
- France
- Volunteers
- 61 people
- Sponsor
- University Hospital, Brest
Adrenal Tumor
18FDG PET Textural Indices in Adrenal Lesion
Tumors are characterized by a great heterogeneity. Characterizing this intra-tumor heterogeneity is a major challenge in oncology to improve the therapeutic management and move towards personalized medicine adapted to each…
- Trial name
- ImpactTexture (NCT03469102)
- Where
- France
- Volunteers
- 53 people
- Sponsor
- University Hospital, Brest