Clinical trials: sponsored by University Hospital, Brest
Cancer of Head and Neck
Prognostic Value of 18FDG PET/CT Textural Indices in HNSCC
Head and neck (HN) cancer is the sixth most common malignancy worldwide, with around 800,000 new cases and 320,000 deaths in 2015.
- Trial name
- ImpactTextureO (NCT03378193)
- Where
- France
- Volunteers
- 284 people
- Sponsor
- University Hospital, Brest
Prostate Cancer
Prognostic Value of SPECT-CT Quantitative Indices for the Response Assessment of Bone Metastatic Prostate Carcinoma
Prognostic interest of bone scintigraphy in bone metastatic prostate carcinoma (BMPC) has been shown. Recent technological advances allow to perform quantitative bone SPECT-CT in routine practice.
- Trial name
- INTEVOPROSTATE (NCT03382522)
- Where
- France
- Volunteers
- 19 people
- Sponsor
- University Hospital, Brest
HTPPE, Idiopathic Pulmonary Embolism
Determine the Frequency of a HTPPE in 5 Years (± on 1 Year) After a First Episode of Idiopathic Pulmonary Embolism.
Forward-looking troop established(constituted) by the patients having been included in the study " PADIS EP ", PHRC on 2006 and 2009, randomized checked(controlled), double-blind, comparing an anticoagulating…
- Trial name
- PADIS-HTP (NCT01894204)
- Testing
- HTPPE
- Where
- 8 sites in France
- Volunteers
- 235 people
- Sponsor
- University Hospital, Brest
Juvenile Idiopathic Arthritis
Therapeutic Alliance is it Associated With Better Compliance Amongst Children With Juvenile Idiopathic Arthritis ?
to evalute if therapeutic alliance is related to adherence in JIA
- Trial name
- ALLIANCE (NCT02824978)
- Where
- 17 sites in France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Brest
Hypophosphatemia, Infection
Hypophosphatemia as a Predictive Marker of Mortality During Sepsis in ICU
Retrospective study in the 3 intensive care units of the Brest Teaching Hospital (France) during a 18-months period (June 2014 -December 2015) to study the independent association between hypophosphatemia and 90-day mortality.
- Trial name
- PORPOISE-REA (NCT03529058)
- Where
- France
- Volunteers
- 193 people
- Sponsor
- University Hospital, Brest
Endodontic Treatment
Stress Factors Induced by Patient and Young Clinicien During Endodontic Treatment
The aim of this pilot study is to examine the patient's induced stress and the young dentist's induced stress, during endodontic treatment.
- Trial name
- STRESSENDO (NCT03217760)
- Testing
- Endodontic treatment, VAS of stress, CORAH scale
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Axillary Block
Descriptive Assessment of Practice in Anaesthesia : Lidocaine 1% Adrenaline Under in Axillary Block Realization
Axillary block is the good anesthetic technique for upper limb surgery without exceeding a certain total dose injected of Local Anesthetic (AL). The maximal recommended dose of Lidocaine adrenaline in the upper limb is 500 mg.
- Trial name
- fLACON (NCT03290404)
- Where
- 3 sites in France
- Volunteers
- 292 people
- Sponsor
- University Hospital, Brest
End Stage Renal Diseases
Evaluation of a Marine OXYgen Carrier: HEMO2Life® for hypOthermic Kidney Graft Preservation, Before Transplantation (OXYOP)
Kidney transplantation is the treatment of choice for end stage renal diseases, increasing life expectancy and quality of life. Improvement in organ preservation is a critical issue in this context.
- Trial name
- NCT02652520
- Testing
- HEMO2Life® use in organ preservation solution
- Where
- 6 sites in France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Brest
Duchenne Dystrophy Muscular
Biomechanical and Morphological Changes in Dystrophic Muscle
The loss of ability to walk in many children with DMD (Duchenne muscular Dystrophy) is a pejorative event. Biomechanical and morphological unknowledge about the loss of the walk ability in children with DMD is an obstacle in…
- Trial name
- MARCHE-DMD (NCT02472990)
- Where
- 10 sites in France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Pregnancy Anemia
Prevalence Study of the Etiology of Pregnancy Anemia
Anemia during pregnancy occurs in 41% of women. The most common etiology is iron deficiency, but studies to determine prevalence of other causes of anemia in pregnancy are still lacking.
- Trial name
- PREGAN (NCT03448432)
- Where
- France
- Volunteers
- 700 people
- Sponsor
- University Hospital, Brest
Whipple Disease
Detection and Characteristic of Whipple Diseases in the Great Britany
Whipple's disease is a chronic systemic infection caused by ubiquitous bacterium Tropheryma wipplei on a genetic predisposition which should be considered in patients with recurrent episodes of seronegative arthritis, erosive or…
- Trial name
- WHO (NCT03350685)
- Where
- 8 sites in France
- Volunteers
- 267 people
- Sponsor
- University Hospital, Brest
Esophageal Cancer, Esophageal Surgery Cancer
Predictive Factors of Survival With and Without Repetition With 5 and 10 Years Curative Post-oesophagectomy for Cancer of the Oesophagus
Prospective study of Predictive Factors of Survival With and Without Repetition With 5 and 10 Years Curative Post-oesophagectomy for Cancer of the Oesophagus
- Conditions
- Esophageal Cancer, Esophageal Surgery Cancer, Overall Survival
- Trial name
- RESARPO (NCT03410758)
- Where
- France
- Volunteers
- 245 people
- Sponsor
- University Hospital, Brest
Blood Loss After a Total Hip Replacement
Blood-sparing During Hip Prosthesis Surgery With Exacyl® in Patients Treated With Rivaroxaban
This study evaluates the efficacy of tranexamic acid versus placebo on perioperative blood loss using two dosage regimens (standard and extended) after a surgery during total hip arthroplasty in patients receiving the novel…
- Trial name
- ESPER (NCT02403596)
- Testing
- Exacyl®
- Where
- 4 sites in France
- Volunteers
- 231 people
- Sponsor
- University Hospital, Brest
Healthy
Study of the ANI Validity on Evaluation of Nociception in State of Hypnosis
Healthy subjects should assess pain on a numerical scale (EN), during painful skin stimuli of variable intensity delivered by a CO2 laser used at the power of 0.3 W, known for its safety.
- Trial name
- NCT02302313
- Testing
- CO2 laser and ANI monitor
- Where
- France
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Gastro Intestinal Bleeding
Management of Digestive Haemorrhaging In CHRU of Brest During 2009 and 2014
Gastro intestinal (GI) bleeding is relatively frequent and may lead to intensive care unit admission. Although a restrictive strategy for red blood cell transfusion is supported by a large randomized controlled trial literature…
- Trial name
- HDréa (NCT03379285)
- Where
- France
- Volunteers
- 272 people
- Sponsor
- University Hospital, Brest
Glioblastoma Multiforme, Anaplastic Astrocytoma
FET-PET and Multiparametric MRI for High-grade Glioma Patients Undergoing Radiotherapy
Glioblastoma is the most common malignant brain tumor in adults. The primary treatment consists of maximal tumor removal followed by radiotherapy (RT) with concomitant and adjuvant temozolomide.
- Conditions
- Glioblastoma Multiforme, Anaplastic Astrocytoma, Radiotherapy
- Trial name
- IMAGG (NCT03370926)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Brest
Hemophilia
Health Practice of Hemophilia Patiente Care During Pregnancy, Delivery and Newborn Children
Prenancy and specialy delivery for hemophilia mother and her children possibly hemophilia is risked. Diagnostical of hemophilia pregnan is the first difficulty but patients with hemorrhagic menstruation without etiology known…
- Trial name
- ECHANGE (NCT03360149)
- Where
- 7 sites in France
- Volunteers
- 35 people
- Sponsor
- University Hospital, Brest
Dental Pulp Capping
3-months Success Rate of Direct Pulp Capping With Biodentine®
Biodentine® is a most recent material for direct pulp capping. The aim of this study is to determine the 3 months success rate (defined as clinical and radiographic successes together) of direct pulp capping realized with…
- Trial name
- CPDB (NCT02891876)
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Brest
Out-of-Hospital Cardiac Arrest
Early-onset Pneumonia After Out-of-hospital Cardiac Arrest
Early-onset pneumonia after out-of-hospital cardiac arrest is frequent. An association between early-onset pneumonia and an increase in morbidity has been reported in this population.
- Trial name
- PP-ACR (NCT03355885)
- Where
- France
- Volunteers
- 240 people
- Sponsor
- University Hospital, Brest
Bone Metastases
Double-bed SPECT/CT for Bone Scintigraphy in Initial Staging of Cancer Patients
Bone scintigraphy is currently a reference test in the initial staging of cancer. Bone scintigraphy historically consists in a planar whole-body scintigraphy (WBS).
- Trial name
- DTOM (NCT03353090)
- Where
- France
- Volunteers
- 102 people
- Sponsor
- University Hospital, Brest