Clinical trials: sponsored by University Hospital, Brest
Fatigue Symptom
Validation of the French Version of the Fatigue Score "Brief Fatigue Inventory ( BFI)".
Fatigue, or asthenia, is an important symptom for the diagnosis and follow-up of patients in routine as well as research oriented clinical practice.
- Trial name
- EAMG (NCT02645812)
- Sponsor
- University Hospital, Brest
Cataract, Exfoliative Glaucoma
Measurement of Ocular Tensional Fluctuation by Triggerfish Lens Before and After Cataract Surgery in Patients With Exfoliative Glaucoma
Glaucoma is a very frequent disease in Brittany. In glaucoma the retinal ganglion cells and their axons slowly die with visible changes at the optic nerve head (cupping).
- Trial name
- TRIGGERFISH (NCT02658071)
- Where
- France
- Volunteers
- 6 people
- Sponsor
- University Hospital, Brest
Renal Transplant
Influence of Thymoglobuline on Phenotypic and Functional Profiles of B Lymphocytes in Renal Transplant Recipients
The investigators expect to better characterise B cell subpopulation and functional properties early after graft, to analyse effect of induction therapy (thymoglobulin versus basiliximab) on B cells, and to compare this B cell…
- Trial name
- THYMO B (NCT02894606)
- Testing
- Thymoglobulin Induction, Basiliximab Induction
- Where
- 2 sites in France
- Volunteers
- 49 people
- Sponsor
- University Hospital, Brest
Renal Transplant
B Cell Lymphocyte in Humoral Rejection and Alloimmunisation
This study aims to better characterise B cell phenotype and functional abnormalities in kidney transplant patients producing donor specific antibody (DSA) and in those with chronic antibody mediated rejection (cAMR) and to search…
- Trial name
- BHL (NCT03016455)
- Testing
- Presence of DSA w/ cAMR, Presence of DSA w/o cAMR, No DSA No cAMR
- Where
- 13 sites in France
- Volunteers
- 116 people
- Sponsor
- University Hospital, Brest
Neoplasms,Ovarian
Urinary Human Papilloma Virus Test in the General Population in Brittany
This is a population-based, prospective, multicenter and open-label study. 12,500 female non-respondents to the uterine cervix smear from 30 to 65 years of age in the context of the organized cervical cancer screening of the…
- Trial name
- PapU-Access (NCT03598946)
- Testing
- Urinary test
- Where
- France
- Volunteers
- 1,809 people
- Sponsor
- University Hospital, Brest
Polymyalgia Rheumatica
Abatacept in earLy Onset Polymyalgia Rheumatica: Study ALORS
Polymyalgia rheumatic (PMR) is a frequent inflammatory disease. It affects the elderly, with peak incidences at the age of 70 to 80 years; an age >50 years or older, is considered a criterion for the diagnosis.
- Trial name
- ALORS (NCT03632187)
- Testing
- Abatacept
- Where
- 5 sites in France
- Volunteers
- 34 people
- Sponsor
- University Hospital, Brest
Physical Activity, Breast Cancer
Study of Program Interest "Bouge" to Improve the Daily Physical Activity in Processings Treatment of Non-metastatic Breast Cancer
Evaluate the "Bouge" digital program (smartphone application) to increase the daily physical activity of breast cancer patients
- Conditions
- Physical Activity, Breast Cancer, Mobile Health Apps
- Trial name
- BOUGE CANCER (NCT03674515)
- Testing
- Smartphone equipped with application "bouge" = Coach group
- Where
- 2 sites in France
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Physical Activity, Pregnant
Study of Programm Interest 'Bouge' to Improve the Daily Physical Activity at the Pregnant Women.
Evaluate the "Bouge" digital program (smartphone application) to increase the daily physical activity of pregnant patients beguining at 15 SA
- Conditions
- Physical Activity, Pregnant, Mobile Health Apps
- Trial name
- BOUGE GROSSESS (NCT03688087)
- Testing
- Smartphone equipped with application "bouge" = Coach group
- Where
- 4 sites in France
- Volunteers
- 250 people
- Sponsor
- University Hospital, Brest
Coxarthrosis; Primary, Coxarthrosis; Secondary
Is the Dynamic of the Pelvic Bone Altered After a Total Hip Replacement ?
Total hip replacement is one of the most common surgical procedure in France. In 2010, an estimated 147 513 total hip procedures were performed. This number is constantly increasing.
- Trial name
- DYPAMAT (NCT04587440)
- Testing
- Pelvic inclination measurement
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Brest
Early Intervention in Remote Autism
Early Intervention in Remote Autism (IPAAD)
The Early Start Denver Model (ESDM) has shown its efficiency in the early management of ASD. The study aims to evaluate the efficiency of a new type of management based on a semi-intensive center-based intervention (8h per week)…
- Trial name
- IPAAD (NCT04660669)
- Testing
- ESDM intervention, MOOC
- Where
- 4 sites in France
- Volunteers
- 90 people
- Sponsor
- University Hospital, Brest
Venous Thromboembolism (VTE)
Molecular Imaging of Active Venous Thrombus With Positron Emission Tomography (PET)
Venous thromboembolism (VTE), which includes deep vein thrombosis (DVT) and/or pulmonary embolism (PE), is a major public health issue.
- Trial name
- THROMPET (NCT06057844)
- Testing
- Additional blood sampling
- Where
- France
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Hematoma, Subdural
Platelet Activity Monitoring for Patients Under Adp Medication Using Verify Now in Subdural Hematoma
The brain is encased in three membranes: the pia mater, arachnoid, and dura mater. A subdural hematoma is often a post-traumatic accumulation of blood between the dura mater and the brain, occurring when a trauma tears a small…
- Trial name
- PAPAYE (NCT06415422)
- Testing
- Biological samples
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Brest
Polymyalgia Rheumatica, Inflammatory Rheumatism
Justification of the Initial Diagnosis and Evaluation of the Overall Evolution of a Cohort of Recent Polymyalgia Rheumatica (JADORE)
Pseudo-rheumatoid arthritis (PRA) is a common inflammatory rheumatic disease of the elderly, characterized by inflammatory shoulder and/or hip pain.
- Trial name
- JADORE (NCT07132164)
- Testing
- biobank sample collection
- Where
- 30 sites in France
- Volunteers
- 400 people
- Sponsor
- University Hospital, Brest
Hematology, Graft, Mobilization
Results of Peripheral Blood Stem Cells According to Stimulatory Molecule,: Zarzio Versus Granocytes
Investigator therefore propose a retrospective mono-centric study, to compare the results obtained in patients with myeloma or lymphoma, mobilized with Zarzio® in order to obtain a graft, with the results obtained in our study.
- Trial name
- ZAG (NCT03367117)
- Where
- France
- Volunteers
- 70 people
- Sponsor
- University Hospital, Brest
Psychotic Disorders, Psychosis
Semantic and Syntactic Computerized Analysis of Free Speech
Subtle speech disorganization could be predictive of a transition to schizophrenia of ultra-high-risk patients. The aim of our longitudinal multicenter cohort study is to identify specific linguistic markers of the psychotic…
- Conditions
- Psychotic Disorders, Psychosis, Schizophrenia and Related Disorders, Schizophrenia Prodromal
- Trial name
- ASESID (NCT03525054)
- Where
- 3 sites in France
- Volunteers
- 215 people
- Sponsor
- University Hospital, Brest
Atopic Dermatosis, Alloknesie
Study of Alloknesia in Atopic Dermatitis
Alloknesia is defined as pruritus (= itching) triggered by light mechanical stimuli, which are responsible for the perception of light touch under physiological conditions, but which are perceived as pruritic under pathological…
- Trial name
- ALLOKNESIE (NCT06923202)
- Where
- 8 sites in France
- Volunteers
- 160 people
- Sponsor
- University Hospital, Brest
Craniocervical Surgery
Improved Understanding of Venous Drainage at the Cranio-cervical Junction : Study of Postoperative Venous Remodeling Following Surgical Treatment of Lesions of the Posterior Fossa or Posterior Approach of the Upper Cervical Spine.
In the literature, a dichotomous view of cerebral venous drainage is most commonly found. Thus, two drainage pathways are most often considered: the jugular vein network and the vertebral artery plexus.
- Trial name
- VENAMAP 2 (NCT07206667)
- Testing
- T1 GRE GADO MRI sequence
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Brest
Distal Amputation of the Fingers
Lipofilling Versus Conservative Treatment in Fingertips Injuries Sequelae
The purpose of this study is to evaluate the contribution of autologous graft reinjection (lipofilling) in the treatment of dysaesthesic pulp.
- Trial name
- LIPOFILLING (NCT04076397)
- Testing
- autologous transplant reinjection, desensitization
- Where
- 2 sites in France
- Sponsor
- University Hospital, Brest
Osteoarthritis, Knee
Is Non Surgical CaRE Using Treat to Target Multimodal meDIcal Strategies aBLE to Delay or Avoid Total Knee Replacement?
Knee is the most common site of osteoarthritis. Treatment of knee osteoarthritis starts with a full course of medical therapy, followed by surgery to replace the knee with a prosthesis if this strategy fails, or in advanced…
- Trial name
- INCREDIBLE (NCT06643845)
- Testing
- arthroplasty, Medical and non-medical treatments
- Where
- 21 sites in France
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Brest
Refractive Errors, Ametropia
Performance of Refractometers With Self-adjusting Lenses Compared to Cycloplegia in Children (REFRALENS)
This study aimed to compare refractive measurements using Vision-S™ 700, an immersive and compact phoropter with a tunable-focus lens, and Vision-R™ 800, a phoropter with a tunable-focus lens without immersion, with cycloplegic…
- Trial name
- REFRALENS (NCT06668246)
- Testing
- Vision-S™ 700, an immersive and compact phoropter with a tunable-focus lens, and Vision-R™ 800, a phoropter with a tunable-focus lens without immersion, with cycloplegic refraction serving as the gold
- Where
- France
- Volunteers
- 43 people
- Sponsor
- University Hospital, Brest