Clinical trials: sponsored by University Hospital, Caen
Anxiety State, Sleep Disturbance
Anxiety/Depression, Sleep and Alcohol in Elderly Anxiety/Depression, Sleep Disturbances and Alcohol Use Disorder in Elderly With Cognitive Complaints
The goal of MEM-ASA is to investigate the prevalence of anxiety/depression, sleep disturbances and alcohol use disorder in elderly with cognitive complaints.
- Conditions
- Anxiety State, Sleep Disturbance, Alcohol Abuse, Aging
- Trial name
- MEM-ASA (NCT04368416)
- Where
- France
- Volunteers
- 3,000 people
- Sponsor
- University Hospital, Caen
Hemodialysis, Renal Insufficiency, Chronic
Feasibility and Evaluation Study of the UPLUG Hemodialysis Connection Device
The new Uplug° technology, interface between the end of the hemodialysis catheter and the dialysis circuit, makes it possible to limit direct access to the hemodialysis catheter during connections and disconnections.
- Trial name
- UPLUG-SAFE (NCT05419258)
- Testing
- UPLUG Hemodialysis Connection Device
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Caen
Cardiac Remodeling, Ventricular
Intracardiac Flow Remodeling in Athletes
The uncertainty concerning the onset and the extent of cardiac remodeling in response to intensive training hinders medical evaluation by physician.
- Trial name
- INFINITE (NCT03076788)
- Testing
- electrocardiogram and echocardiography
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Microbial Colonization, Viral Infection
Follow-up of the Nasal Microbiome and Viral Infections in Newborns Hospitalised in Neonatology.
The goal of this interventional study is to learn about nasal microbiome and viral infections in newborns hospitalised in neonatology.
- Conditions
- Microbial Colonization, Viral Infection, Neonatal Infection
- Trial name
- NEOBIOME (NCT05717283)
- Testing
- Nasal swab
- Where
- France
- Volunteers
- 38 people
- Sponsor
- University Hospital, Caen
Cancer
Acute Lymphoblastic Leukaemia Related to Lenalidomide (LenALL)
Although lenalidomide (LEN) have proved effective in treating many cancers, few patients receiving LEN may experience rare but life-threatening adverse events such as Acute Lymphoblastic Leukaemia (ALL).
- Trial name
- NCT06251648
- Testing
- Lenalidomide
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Caen
Chronic Kidney Diseases
Geriatric Assessment for Older Kidney Transplantation Candidates
Geriatric assessment is now widely used to decide whether older patients with chronic kidney disease should be put on the kidney transplantation waiting list.
- Trial name
- NCT05395247
- Testing
- Geriatric assessment
- Where
- France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Caen
Glioma, Malignant
Monitoring of Patients With Diffuse Gliomas Using Circulating miRNAs
MicroRNAs are small non-coding RNAs involved in the post-transcriptional regulation of genes and, consequently, of intracellular signalling pathways that govern cellular behaviour (Komatsu et al., 2023).
- Trial name
- GliomiR (NCT06203496)
- Testing
- Blood sample
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Caen
Atrial Fibrillation Recurrent
SPironolactONe for the Maintenance of Sinus Rhythm in Patients With Atrial Fibrillation
Introduction: There is evidence that aldosterone and the activation of its receptor, mineralocorticoid receptor (MR), promote cardiac fibrosis and electrical disturbances.
- Trial name
- SPONSoR (NCT06204640)
- Testing
- Spironolactone
- Volunteers
- 580 people
- Sponsor
- University Hospital, Caen
Sigmoid Diverticulosis, Colorectal Surgery
Impact of Socioeconomic and Territorial Inequalities on Surgical Management of Sigmoid Diverticulitis
Sigmoid diverticulitis (SD) is a common pathology characterized by inflammation/infection of a diverticulum in the sigmoid colon.
- Trial name
- EDIVERTICULITE (NCT06200857)
- Where
- France
- Volunteers
- 6,800 people
- Sponsor
- University Hospital, Caen
Preventive Care
Oral Feeding Delay Prevention in Preterm Newborns
Preventing oral feeding delays in preterm newborns remains a stake for NICU nowadays. Indeed, it lengthens hospitalization duration, distorts parent-newborns relationships, and increases the risks of adverse nursing outcomes.
- Trial name
- PARENTALIM (NCT06184386)
- Testing
- NIDCAPARENTALIM, SOFS
- Where
- France
- Volunteers
- 43 people
- Sponsor
- University Hospital, Caen
Premature Infant
Evaluation of the Risks and Benefits of Abdominal Massage Treatment in Neonatalogy in Premature Children
Premature birth creates difficulties for the child in starting his diet and digestion. The immaturity of the major vital functions complicates the abdominal transit.
- Trial name
- PREMASS (NCT03681782)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Caen
Peritoneal Dialysis
Usefulness of Sterile Adhesive Dressing at the Exit-site of Peritoneal Dialysis Catheter
Infection of peritoneal dialysis fluid is a major complication in patients treated with peritoneal dialysis (PD). The aim of catheter emergence care is to reduce bacterial contamination of the peritoneum.
- Trial name
- PANCADIPE (NCT03677063)
- Testing
- No dressing
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Caen
Pelvic Girdle Pain, Pregnancy Related
Cross-cultural Adaptation and Validation of the Pelvic Girdle Questionnaire in French Language
The objective of this study is the adaptation of the Pelvic Girdle Questionnaire to the French language from France, and the analysis of its psychometric properties.
- Conditions
- Pelvic Girdle Pain, Pregnancy Related, Postpartum Period
- Trial name
- PELVIC (NCT03436888)
- Where
- 2 sites in France
- Volunteers
- 134 people
- Sponsor
- University Hospital, Caen
BTKi-induced Atrial Fibrillation, Hematologic Malignancy
IRAF-ABLATION Study: a Multicenter International Retrospective Cohort of Patients With BTK Inhibitors-related AF Treated by Catheter Ablation
Targeted anticancer drugs have completely changed the prognosis of malignancies during the past decades. Patients suffering from malignancies live longer and this allows adverse events of anticancer drugs to emerge, notably…
- Conditions
- BTKi-induced Atrial Fibrillation, Hematologic Malignancy, Atrial Fibrillation Catheter Ablation
- Trial name
- NCT06130709
- Testing
- Atrial fibrillation catheter ablation in a population of BTKi-induced atrial fibrillation
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Caen
Atrial Fibrillation
Identification of Immunomodulators Associated With Atrial Fibrillation Reporting: Analysis of the WHO Pharmacovigilance Database
Atrial fibrillation is the most prevalent sustained arrhythmia worldwide with a great morbimortality. Some populations are more at risk to develop atrial fibrillation like patients suffering from inflammatory diseases or patients…
- Trial name
- NCT06095791
- Testing
- Immunomodulators with FDA approval on the 1st January 2023.
- Where
- France
- Volunteers
- 4,000,000 people
- Sponsor
- University Hospital, Caen
Hematologic Cancer
Research-Action in Hematology From Hospitalization to Home
Objective : To study and support the hospitalization and the return home of patients with the help of a psychological follow-up started in a hospital institution and which will continue in the patient's home, based on the…
- Trial name
- RAH HD (NCT06053918)
- Testing
- additional follow-up extension at home
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Caen
Visual Acuity, Accidental Fall
Nurses Ability to Assess Visual Acuity in Geriatric Consultation
Nurses participate to geriatric evaluations for falling patients. For these patients, it is recommended to evaluate,especially, visual acuity but this is not currently done because it is difficult to systematically combine with…
- Conditions
- Visual Acuity, Accidental Fall, Aging, Nurse's Role
- Trial name
- AVIGE (NCT03076606)
- Testing
- ophthalmologist examination
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Caen
Biliary Stricture, Biopsy Wound
Percutaneous Transluminal Forceps Biopsy
To evaluate during a 7 months period the efficacy, safety and accuracy of percutaneous transluminal forceps biopsy combined with transhepatic biliary drainage in patients with biliary stricture
- Conditions
- Biliary Stricture, Biopsy Wound, Oncology
- Trial name
- NCT06039670
- Testing
- biliary biopsy
- Volunteers
- 50 people
- Sponsor
- University Hospital, Caen
Atrial Fibrillation
Subcutaneous Cardiac Monitoring of Patients With BTK Inhibitors
The goal of this clinical trial is to screen all types of electrocardiographic changes and rhythm disorders in adult patients with a hematologic malignancy requiring a treatment by Bruton's tyrosine kinase (BTK) inhibitor…
- Trial name
- IRAF-ISCM (NCT06029166)
- Testing
- Insertable subcutaneous cardiac monitor (BIOMONITOR IIIm®, Biotronik®)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Caen
Rectal Cancer Patients
Validation of the French Version of the Low Anterior Resection Syndrome (LARS) Among Rectal Cancer Patients
Oncological rectal cancer outcomes have improved considerably because of optimal surgery by total mesorectal excision in conjunction with multidisciplinary team management by selective multimodal therapy (ie, neo-adjuvant…
- Trial name
- LARS (NCT03569488)
- Testing
- FT-LARS questionnaire
- Where
- 8 sites in France
- Volunteers
- 1,100 people
- Sponsor
- University Hospital, Caen