Clinical trials: sponsored by University Hospital, Caen
Sport Injury, Shoulder Injuries
Shoulder Muscle Imbalance as a Risk Factor for Shoulder Injury in Elite Badminton Players
Background: To assess the impact of pre-season clinical measures and rotator muscles strength on the risk of significant shoulder injury (SSI) in elite badminton players Design: Prospective cohort study Participants: Nineteen…
- Trial name
- BADEPAULE (NCT04486807)
- Testing
- Elite badminton players
- Where
- France
- Volunteers
- 19 people
- Sponsor
- University Hospital, Caen
Accident, Traffic
Evaluation of Reporting of Road Traffic Accidents With Drugs Responsible for Cognitive Side Effects (ERoADS)
Drugs responsible for cognitive and psychomotor side effects may lead to impaired driving skills and road traffic accidents. This study investigates reports of road traffic accident for different class of drugs responsible for…
- Trial name
- ERoADS (NCT04480996)
- Testing
- Drugs Responsible for Cognitive Side Effects
- Where
- France
- Volunteers
- 500,000 people
- Sponsor
- University Hospital, Caen
Peripheral Arterial Disease, Atherosclerosis Obliterans
Comparison of 3 Ultrasonic Techniques for Measuring the Systolic Pressure Index
Continuous Doppler ankle brachial index (ABI) is the gold standard for screening and monitoring of peripheral arterial disease (PAD) but is no longer carried out in clinical practice.
- Conditions
- Peripheral Arterial Disease, Atherosclerosis Obliterans, Atherosclerosis Right Leg, Atherosclerosis Left Leg
- Trial name
- ABIPULSE (NCT04440072)
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Caen
ACL Tear, ACL - Anterior Cruciate Ligament Deficiency
Proprioceptive Isokinetic Repositioning, Functional Testing, and a Self-reported Questionnaire Before and After Anterior Cruciate Ligament Reconstruction
This prospectively study aims to evaluate the evolution of knee joint proprioception on isokinetic dynamometer before and after Anterior Cruciate Ligament (ACL) reconstruction and its relationships with muscle strength, self…
- Trial name
- PRO-ACL (NCT04058574)
- Testing
- Proprioception measurement on isokinetic dynamometer
- Where
- 2 sites in France
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
ACL - Anterior Cruciate Ligament Deficiency, Muscle Weakness
Isokinetic Muscular Assessment After ACL Ligamentoplasty: Study of Factors Predictive of Muscle Imbalance.
Despite advances in surgery and rehabilitation, the return to sport after anterior cruciate ligament (ACL) reconstruction surgery remains a major challenge. challenge.
- Trial name
- PREDICT-ACL (NCT04071912)
- Where
- France
- Volunteers
- 113 people
- Sponsor
- University Hospital, Caen
Covid-19, Cancer
COVID-19 in Pediatric Oncology and Hematology Centers in France
Since the description of the first cases of infection in December 2019 in the Hubei province in China, a new coronavirus, called SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2), emerged and caused a pandemic.
- Trial name
- PEDONCOVID (NCT04433871)
- Testing
- No intervention, observational
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Caen
Acute Respiratory Distress Syndrome
Maneuver for Evaluating the Potential Recruitability of the Pulmonary Parenchyme in Patients With ARDS
This study will try to define the threshold of the recruitable volume (Vrec), obtained by a derecruitment maneuver, that permit to identify patients responder or not to alveolar recruitment maneuvers.
- Trial name
- MERP (NCT04387669)
- Where
- France
- Volunteers
- 42 people
- Sponsor
- University Hospital, Caen
Epidural; Anesthesia
Does Ultrasound Increase the First-pass Success of Epidural Space Identification in Obese Parturients
Obesity is associated with difficulties in epidural space catheterization. The investigators want to prove that a pre-procedural ultrasound exam of lumbar spine increase the first-pass success rate of the epidural space…
- Trial name
- NCT04352283
- Testing
- Preprocedural ultrasound exam of lumbar spine
- Where
- France
- Volunteers
- 56 people
- Sponsor
- University Hospital, Caen
Quality of Life, Brain Metastases
Evaluation of the Best Treatment in Terms of Quality of Life for Patients Having a Brain Metastasis
Main Goal : evaluation of quality of life for patient having a brain metastasis and allowed to have either surgery and radiosurgery of the surgical site or only hypofractionned radiosurgery on the lesion.
- Trial name
- OPTMETACER (NCT04358666)
- Testing
- surgery and focal radiosurgery of the surgical bed
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Caen
Antibiotic Prophylaxis, Adult Heart Transplantation
Antibiotic Prophylaxis in Adult Heart Transplantation: a French National Survey
The study focuses on the antibiotic prophylaxis use in adult heart transplantation in France.
- Trial name
- ATC (NCT02479503)
- Testing
- Antibiotic prophylaxis in adult heart transplantation
- Where
- France
- Volunteers
- 21 people
- Sponsor
- University Hospital, Caen
Type 2 Diabetes Mellitus in Obese, Bariatric Surgery Candidate
Glycemic Profile by CGMS in Diabetic Patients After Bariatric Surgery
The aim of this observational prospective monocentric study is to examine glycemic patterns in adult T2D patients candidates to bariatric surgery, by using a continuous glucose monitoring (CGM) sensor over 14 days post-surgery…
- Trial name
- CGM-BARIA (NCT04332354)
- Testing
- routine care. No intervention
- Volunteers
- 31 people
- Sponsor
- University Hospital, Caen
Rheumatoid Arthritis
Biomarkers in Rheumatoid Arthritis Treated With Anti-interleukin-6 Therapy
The use of anti-interleukin (IL)-6 therapy, including tocilizumab, in rheumatoid arthritis or giant cell arteritis, led to the improvement or even control of disease in some patients for whom no further therapeutic options were…
- Trial name
- INTER-ACT (NCT04281602)
- Where
- France
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Accidental Falls, Fractures
Falls With Fracture : Role of Cognitive Disorders and Comparison With Bone Fragility
The purpose of this study is to determine whether cognitive disorders are a risk factor for a fracture after a fall independently of a bone fragility.
- Trial name
- CFC (NCT02292316)
- Testing
- gait and cognitive assessments, blood sample, osteodensitometry
- Where
- 2 sites in France
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Weightlessness, Cerebral Blood Flow
Cerebral Blood Flow Distribution During Parabolic Flight-induced Microgravity
When astronauts return from space flight, they manifest a set of symptoms, the most striking of which is orthostatic intolerance, that is, the inability to stay upright.
- Trial name
- GraCer (NCT03986788)
- Testing
- Weightlessness
- Where
- France
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Sciatica
Ultrasound-guided Caudal or Interlaminar Corticosteroid Epidural Injection for Sciatica
An open-label randomized trial to compare the efficacy of ultrasound-guided caudal and interlaminar corticosteroid injections for the treatment of lumbar disk herniation-related sciatica.
- Trial name
- HiatUS (NCT02897336)
- Testing
- ultrasound-guided, interlaminar
- Where
- France
- Sponsor
- University Hospital, Caen
Alcoholic or Viral C Compensated Cirrhosis
Influence of ABO Blood Group on the Risk of Complications in Alcoholic or Viral C Cirrhosis?
The non-O blood group is a risk factor of deep vein thrombosis and recurrence of thromboembolic events, especially when associated with Factor 5 Leiden or prothrombin G20210A mutations.
- Trial name
- ABOCIRRALVIR (NCT03342170)
- Testing
- G20210A prothrombin gene mutation and Factor 5 Leiden mutation
- Where
- France
- Volunteers
- 1,500 people
- Sponsor
- University Hospital, Caen
Multiple Sclerosis, Malignant Tumor
Drugs for the Treatment of Multiple Sclerosis and Risk of Cancer: a Pharmacovigilance Analysis in Vigibase
Even though the therapeutic panel for multiple sclerosis (MS) treatment has improved in the last 20 years, safety data especially for the second-line and innovative treatments are lacking.
- Trial name
- PVSEPK (NCT04237337)
- Testing
- Exposure to MS drugs
- Volunteers
- 200,000 people
- Sponsor
- University Hospital, Caen
C10.114.375.500
Influence of Socio-Economic Factor on Net Survival in Patients With Multiple Sclerosis in France ( ECOVIMUS).
Background: In comparison to general population, persons with Multiple Sclerosis have a higher risk to premature death with an estimate reduced life expectancy from 7 to 14 years.
- Trial name
- ECOVIMUS (NCT04028232)
- Where
- 18 sites in France
- Volunteers
- 30,000 people
- Sponsor
- University Hospital, Caen
Peritoneal Dialysis
Evaluation of Dexterity in Prevalent Peritoneal Dialysis Patients
The objective of the study is to measure the manual dexterity of patients treated by peritoneal dialysis - transversal study
- Trial name
- DEXTER (NCT03900819)
- Testing
- dexterity measurement
- Where
- France
- Volunteers
- 43 people
- Sponsor
- University Hospital, Caen
Inferior Vena Cava Diameter
Comparison of Subcostal and Transhepatic Views to Assess Inferior Vena Cava by Echocardiography
Comparison of subcostal and transhepatic views to measure inferior vena cava diameter by echocardiography in intensive care unit patients
- Trial name
- VCI ECHO (NCT03587090)
- Testing
- echocardiography
- Where
- France
- Volunteers
- 131 people
- Sponsor
- University Hospital, Caen