Clinical trials: sponsored by University Hospital, Caen
Pointing Task, Gasping Task
Effects of Inverted Vision on Pointing and Grasping in Parabolic Flight
Parabolic flight is the only ground-based condition in which weightlessness (0G) can be created long enough for safely testing changes in human perception and behavior.
- Trial name
- SpaceInVision (NCT02885844)
- Testing
- INVERTED VISION, NORMAL VISON
- Where
- France
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Cardiomyopathies
Diagnosis of Fabry Disease: Impact of an Educational Brochure Intended for Cardiologist
The cardiac Fabry disease are early, frequent and severe, dominated by the frequency of left ventricular hypertrophy. They are responsible for a high morbidity and mortality, reducing life expectancy of 15 to 20 years for men.
- Trial name
- TARIFF (NCT02883205)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Caen
Premature Birth
Perception of Temporal Regularity in Tactile Stimulation: a Diffuse Correlation Spectroscopy Study in Preterm Neonates
A key function of our brain is to identify temporal structures in the environment and use them to form expectations. These expectations allow us to plan and organize our behavior towards changes in the environment, and optimize…
- Trial name
- PREMATEMP (NCT02880696)
- Testing
- Regular stimulation sequence, Random stimulation sequence, DCS
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Chronic Kidney Disease
Impact of the Implementation of CKD Coordination Function on Dialysis Initiation Frequency in Emergency
Kidney failure is a major public health problem. REIN registry shows that 33% of patients treated in renal replacement therapy for ESRD start dialysis in emergency.
- Trial name
- ICoDU (NCT02878902)
- Testing
- Post implementation
- Volunteers
- 200 people
- Sponsor
- University Hospital, Caen
Critical Care, Catheterization
Venous Site for Central Catheterization
Central venous catheters are needed in the critical care setting to administer drugs. Three sites are available to gain vascular access: subclavian, internal jugular and femoral.
- Conditions
- Critical Care, Catheterization, ICU
- Trial name
- 3SITES (NCT01479153)
- Testing
- Randomization of the site for catheterization
- Where
- 5 sites in France
- Volunteers
- 3,471 people
- Sponsor
- University Hospital, Caen
Type 2 Diabetes
Effects of Exenatide on Glycemic Control and Weight in Continuous Subcutaneous Insulin Infusion (CSII) Type 2 Treated Patients With Type 2 Diabetes
The purpose of this study is to determine whether exenatide is effective to improve glycemic control among type 2 diabetic patients treated by insulin pump therapy.
- Trial name
- EXEPUMP (NCT01140893)
- Testing
- Exenatide
- Where
- 3 sites in France
- Volunteers
- 110 people
- Sponsor
- University Hospital, Caen
Obsessive Compulsive Disorder, Healthy
Inhibitory Control of the Mind : Neural Bases and Impact for Obsessive-compulsive Disorders
Mental-health conditions affect million people worldwide. The economic burden of mental illness is enormous and the economic health of both developing and developed nations will depend on controlling the staggering growth in…
- Trial name
- SUPTOC (NCT02850393)
- Testing
- Functional magnetic resonance imaging, behavioral measures, physiological measurements
- Where
- France
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Healthy Volunteers
Spatial Orientation and Motor Skills: How to Flip Switches "Down" in Weightlessness?
The purpose of the study is to investigate spatial orientation in weightlessness as it manifests not in perception but rather in motor performance by direction and reaction time of flip switch. Hypotheses are that flip switch: 1.
- Trial name
- Down (NCT02850380)
- Testing
- FLIP SWITCHES "DOWN" IN WEIGHTLESSNESS
- Where
- France
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Healthy Volunteers
Gas Exchange and Cardiovascular Kinetics of Regulation - Effects of Short Term Changes in Gravity
The regulation of the cardiovascular respiratory system after changing environmental conditions or changes in work rates are essential for cognitive as well as physical functioning.
- Trial name
- GasEx (NCT02850354)
- Testing
- anti-g maneuvers
- Where
- France
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Stress Hyperglycemia
Medical ICU Paper-based Dynamic Insulin Protocol
Intensive care unit (ICU) patients commonly display hyperglycemia, even without previously known diabetes. It was demonstrated that hyperglycemia was associated with increased hospital mortality in various medical and surgical…
- Trial name
- NCT02847104
- Testing
- dynamic insulin protocol, static insulin protocol
- Volunteers
- 131 people
- Sponsor
- University Hospital, Caen
Total Hip Arthroplasty
Comparative Study of the Wear of Uncemented Acetabular Conventional Polyethylene and X3 in Total Hip Replacement, for Stereo-radiographic Analysis
Total hip arthroplasty (THA) is one of the most effective medical procedures. Except for the few early complications (acute infections and dislocations), the patient made a PTH can be assured of a significant improvement in its…
- Trial name
- COCYCOX (NCT02525770)
- Testing
- radiostereometric analysis (RSA)
- Where
- France
- Volunteers
- 112 people
- Sponsor
- University Hospital, Caen
Coronary Artery Disease
Myocardial Flow Reserve and 99mTc-DTPA Cardiac Dynamic SPECT
New CZT-based SPECT cameras are potentially capable of dynamic 3-D acquisition. Preliminary results suggested that dynamic acquisitions could allow the assessment of myocardial flow reserve using 99mTc-labelled perfusion tracers.
- Trial name
- Flow-Heart (NCT02844686)
- Testing
- Cardiac SPECT
- Volunteers
- 20 people
- Sponsor
- University Hospital, Caen
Atrial Fibrillation
Electrophysiological Effects of NACOS and AVK on Pulmonary Veins and Left Atrium in Paroxysmal AF Catheter Ablation
Atrial fibrillation (AF) is the most common cardiac arrhythmias with a constantly growing prevalence AF. The purpose of paroxysmal AF processing is to control outbreaks from these pulmonary veins, medicated way (antiarrhythmic)…
- Trial name
- NACO-VP (NCT02814955)
- Where
- France
- Volunteers
- 90 people
- Sponsor
- University Hospital, Caen
Hydroxyzine, Long QT Syndrome
Hydroxyzine and Risk of Prolongation of QT Interval
On 04/30/2015, ANSM (the National Security Agency of Medicines and Health Products) shared an information for general practicioners, pediatricians, anesthesiologists, dermatologists, geriatricians, psychiatrists, community…
- Trial name
- HYDROXYZINE-QT (NCT02814981)
- Where
- France
- Volunteers
- 130 people
- Sponsor
- University Hospital, Caen
Atrial Fibrillation
ALDOsterone for Prediction of Post-Operative Atrial Fibrillation
Post-operative atrial fibrillation (POAF) is a major and frequent complication occurring after cardiac surgery, contributing to prolonged intensive care and hospital stays and is associated with several cardiovascular…
- Trial name
- ALDO-POAF (NCT02814903)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Caen
Healthy Volunteers
Neurocognitive Performance During Space Flight. Validation of a Test Battery
The main objective of this experiment is to evaluate the alterations in brain cortical activity induced by micro- and hypergravity conditions.
- Trial name
- NeuroCog (NCT02805400)
- Testing
- determination of cortical activity
- Where
- France
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
BLOOD PRESSURE
Simultaneous Determination of Blood Pressure by Oscillometry and Photoplethysmography Compared to the Standard Inert Gas Rebreathing Technique
Main objective of the experiment is threefold: 1) to technically test a device for central blood pressure estimation for its applicability in a spaceflight-related environment and on the International Space Station.
- Trial name
- CeCi (NCT02805413)
- Testing
- Détermination and comparison of blood pressure
- Where
- France
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Atrial Fibrillation, Aldosterone
Plasma Aldosterone Levels and Atrial Fibrillation Reduction (ALDO-AF Study)
Atrial fibrillation (AF) is the most common cardiac arrhythmias with a constantly growing prevalence. Two main techniques are used today to restore sinus rhythm: electrical cardioversion and radiofrequency ablation.
- Trial name
- ALDO-AF (NCT02804321)
- Where
- France
- Volunteers
- 170 people
- Sponsor
- University Hospital, Caen
Healthy Volunteers
Effects of Microgravity on Central Aortic Pressure During Parabolic Flights
Cardiovascular events remain the main cause of death of the industrialized world (Global status report on noncommunicable diseases 2010. Geneva, World Health Organization, 2011).
- Trial name
- CapFlight (NCT02789072)
- Testing
- central aortic pressure (measured in mmHg).
- Where
- France
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Healthy Volunteers
Conflict Detection Development During the Reasoning
The study to explore the development of these abilities with age, and called "Development of the conflict detection during the reasoning - Decor" will take place at CYCERON center and will include two groups of 22 participants…
- Trial name
- DéCoR (NCT02788968)
- Testing
- MRI
- Where
- France
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen