Clinical trials: sponsored by University Hospital, Caen
Facial Paresis
Reinnervation of Facial Muscles After Lengthening Temporalis Myoplasty
The purpose of this study is to determine the physiology of nerve healing and the neurotization of the facial muscles after lengthening temporalis myoplasty.
- Trial name
- FacialReinn (NCT01833221)
- Testing
- injection of 1% lidocaine, 2mL for facial nerve block
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Caen
Diffuse Large B Cell Lymphoma
CyBeR Association in Relapsed/Refractory DLBCL
Forty percent of patients with diffuse large B cell lymphoma (DLBCL) have primary refractory or relapsed disease (R/R). For these fit patients, standard treatment in second line therapy is high dose therapy with autologous stem…
- Trial name
- CyBeR-Lymph (NCT02758925)
- Testing
- Rituximab, Bendamustine, Cytarabine
- Volunteers
- 78 people
- Sponsor
- University Hospital, Caen
Surgery, Blood Loss
Epidemiology of Severe Peroperative Bleeding During Scheduled Surgery
Peroperative bleeding has been studied in specific populations exposed to bleeding (i.e. cardiac surgery, orthopedic surgery). Epidemiology of peroperative bleeding and transfusion remain poorly studied in the whole cohort of…
- Trial name
- NCT02311309
- Testing
- Control, Unanticipated bleeding
- Volunteers
- 1,439 people
- Sponsor
- University Hospital, Caen
Anesthesia
Preoxygenation With Positive Inspiratory Pressure During Induction of Anesthesia
Adults patients scheduled for elective surgery were randomly allocated to receive preoxygenation with spontaneous breathing, positive pressure ventilation (positive inspiratory pressure: 12 cmH2O) without PEEP, and with PEEP…
- Trial name
- PREOX (NCT02313766)
- Testing
- PPV : positive pressure ventilation, PEEP : PPV + PEEP
- Volunteers
- 150 people
- Sponsor
- University Hospital, Caen
Heart Failure
Mathematical Models Derived Indices for the Selection and Planning of a Specific Optimal Treatment to the Patient in Heart Failure
Heart failure is a growing throughout pathology in Europe. It is a public health issue and an economic issue. The management to be effective needs to be early but specific.
- Trial name
- VP2HF (NCT02732977)
- Testing
- expert system development
- Volunteers
- 30 people
- Sponsor
- University Hospital, Caen
Heart Failure
Cardiac Rehabilitation of Heart Failure Patients by Telemedicine
The purpose of the READ study is to compare the continuation of the cardiac rehabilitation at home with clinical follow-up, therapeutic education, and advice on the training at the stamina, via telemedicine with the classic…
- Trial name
- READ (NCT00877318)
- Testing
- SCAD information system
- Where
- 2 sites in France
- Volunteers
- 64 people
- Sponsor
- University Hospital, Caen
Cardiac Failure
Tomography Positron Emission Assessment of the Impact of Cardiac Rehabilitation on Coronary Endothelial Function in Cardiac Failure
In patients with heart failure, the drive to the effort has demonstrated its safety and its interest. Patients with heart failure, endothelium-dependent peripheral vasodilatation is impaired by decreased activity of endothelial…
- Trial name
- TEP-READ (NCT02524574)
- Testing
- cardiac Rehabilitation, Tomography Positron Emission
- Where
- France
- Volunteers
- 54 people
- Sponsor
- University Hospital, Caen
Stroke
Ketamine for Thrombolysis in Acute Ischemic Stroke
KETA trial is a nonprofit, double-blind, randomized, controlled pilot trial with aiming to determine if co-administration of ketamine with recombinant of tissue type plasminogen activator (tPA) for thrombolysis in acute ischemic…
- Trial name
- KETA (NCT02258204)
- Testing
- Ketamine
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Caen
Unspecified Disorder of Vestibular Function, Bilateral
Biological Rhythms and Vestibular System
The purpose of this study is to study the relationship between the vestibular system and chronobiology
- Trial name
- REHAB_Rn'V (NCT01839409)
- Testing
- vestibular stimulation
- Where
- France
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Healthy
Human Fine-motor-skills in Weightlessness: Comparison of a Laboratory and an Everyday-like Context
The human performance during weightlessness was tested in a multiplicity of laboratory experiments during parabolic flights and in space.
- Trial name
- FINESKILL (NCT02566213)
- Testing
- Parabolic flight, Motor skills measurements
- Where
- France
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Healthy Volunteers
Interaction of Otolith Stimulation and Carotid Baroreflex in Humans
It is well documented that a few days stay in space induces a change in the vestibular-ocular reflex reflecting a reinterpretation of sensory inputs following the disappearance of gravity.
- Trial name
- OTOBAR (NCT02565095)
- Testing
- Stimulation of the carotid baroreceptors with a pressure system
- Where
- France
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Healthy Volunteers
The Operation of Control Devices During Parabolic Flights: Influence of Weightlessness, Stress and Motivation
The aim of this project is to investigate whether alterations in sensory-motor performances during weightlessness are only of theoretical relevance, or indeed restrict the capacity of the participants.
- Trial name
- Grafism (NCT02563275)
- Testing
- motion analysis system, parabolic flight
- Where
- France
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Healthy Volunteers
The Effect of Gravity on the Muscular Control of Landing From a Jump
In this project, investigators propose to study the jump in different reduced gravity fields obtained during parabolic flights profiles but also during increased gravity fields obtained during turns of the airplane or during the…
- Trial name
- SLS-JUMP (NCT02563223)
- Testing
- Parabolic flight, Subject Loading System
- Where
- France
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Healthy Participants
Human Neutral Body Posture in Weightlessness
The scientific goal of this experiment is to evaluate the performances of our three-dimensional digital model by comparing its prediction computed from underwater data to posture observed during real weightlessness during…
- Trial name
- HYDRONAUT (NCT02563262)
- Testing
- body angles measurements during weightlessness
- Where
- France
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Healthy Volunteers
Influence of Gravity on Dexterity, Hand-eye Coordination and Perception of Orientation and Distances
If investigators know that the anticipatory mechanisms involved in precision grip take into account the gravity, however it is unclear how they adapt to changes in the gravitational level.
- Trial name
- DEXTER0g (NCT02563249)
- Testing
- Parabolic flight, movements of the upper limb, the gripping force, muscle activity and eye-cephalic subject movement measurements
- Where
- France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Healthy Volunteers
Evaluation of 3D Selection Tasks in Parabolic Flight Conditions: Pointing Task in Augmented Reality User Interfaces
During a space mission the crew has to perform a wide variety of tasks under different acceleration conditions. For handling of displays and control items during a mission, the astronaut's performance is strong depended on an…
- Trial name
- 3DPICK (NCT02563236)
- Testing
- Parabolic flight
- Where
- France
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Congenital Adrenal Hyperplasia
COrticosteroid in Congenital Adrenal Hyperplasia
Congenital adrenal hyperplasia (CAH) results from a deficiency of a key enzyme in the biosynthesis of cortisol, mainly 21-hydroxylase, resulting in its classic form a neonatal salt loss syndrome and / or a virilization syndrome…
- Trial name
- COCA (NCT02552251)
- Testing
- Hormonal balance measurements, metabolic balance measurements, bone balance measurements
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Caen
Schizophrenic Disorders
Interest of Repetitive Transcranial Magnetic Stimulation (rTMS) in the Treatment of Auditory Hallucinations
Auditory hallucinations are common (present in 60-70% of cases) and extremely debilitating. Behavioral disorders associated with them can have serious social repercussions.
- Trial name
- TMS HALLU (NCT02525315)
- Testing
- Transcranial magnetic stimulation: rTMS
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Caen
Coronary Artery Disease
Technical Performance of a New Cardiac Technology "IQ-SPECT" Applied to SCINTI-CT Myocardial Imaging With 99mTc-Sestamibi in Coronary Patients
Cardiological examination is one of the major directions in nuclear medicine for detection of myocardial ischemia in patients with suspected coronary artery disease.
- Trial name
- IQSCINTIMYOC (NCT02524600)
- Testing
- myocardial IQ-SPECT imaging applied to scintigraphic imaging, scintigraphic imaging
- Where
- France
- Volunteers
- 103 people
- Sponsor
- University Hospital, Caen
Suicide
Alliance With Therapeutic Entourage in Support of Young Suicidal
Regardless of age, the quality of hospital care, the confidence that the young can have in the health care team, joining parents are pivotal elements and influence followed.
- Trial name
- IPSI2 (NCT02524535)
- Testing
- Therapeutic alliance
- Where
- France
- Volunteers
- 292 people
- Sponsor
- University Hospital, Caen