Clinical trials: sponsored by University Hospital, Caen
Thromboembolism, Arthroplasty Replacement, Knee
Safety Study of Stopping Thromboprophylaxis Based on Ultrasound Results After Total Knee Replacement
The purpose of this study is to determine whether stopping Low Molecular Weight Heparin (LMWH) thromboprophylaxis is safe after total knee joint replacement.
- Trial name
- NCT00362492
- Testing
- Bilateral ultrasound examination 7+/- 2 after surgery
- Where
- 17 sites in France
- Volunteers
- 850 people
- Sponsor
- University Hospital, Caen
Pressure Ulcers
Maggot Therapy for Wound Debridement
The main objective of the trial was to study the efficacy of bagged larvae on wound debridement in comparison to classical treatments.
- Trial name
- MAGGOT (NCT01211236)
- Testing
- application of wound dressing made of bio-bags (vitapads) containing maggots, application of classical hydrogel/alginate wound dressing
- Where
- 3 sites in France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Caen
Myocardial Infarction, Shock, Cardiogenic
Comparison of Standard Treatment Versus Standard Treatment Plus Extracorporeal Life Support (ECLS) in Myocardial Infarction Complicated With Cardiogenic Shock
Cardiogenic shock is currently the main cause of death after myocardial infarction and 50% of deaths occur within the first 48 hours.
- Trial name
- NCT00314847
- Testing
- Extra-Corporeal Life Support -Impella 2.5
- Where
- 13 sites in France
- Volunteers
- 19 people
- Sponsor
- University Hospital, Caen
Aortic Stenosis
Femoral vs Radial Approach and MRI Evaluation of Strokes
Symptomatic cerebral infarction following cardiac catheterization is rare but silent brain injury could occur at an unexpectedly high rate.
- Trial name
- NCT00329979
- Testing
- vascular access site
- Where
- France
- Volunteers
- 152 people
- Sponsor
- University Hospital, Caen
Intubation
Comparison of Three Laryngoscope Blades for Orotracheal Intubation in the Operating Room
The purpose of this study is to determinate if there is a difference in performance provided by three laryngoscope blades: plastic single use, metallic single use and metallic reusable blades.
- Trial name
- Laryngotest (NCT00876967)
- Testing
- metallic single use blade, plastic single use blade, metallic reusable blade
- Where
- France
- Volunteers
- 1,040 people
- Sponsor
- University Hospital, Caen
Hemodialysis
HEMOTOL: Efficacy and Safety of Hemodialysis On-line Monitoring Devices on Hemodynamic Stability in Intensive Care Unit
The purpose of this randomized controlled study is to compare the effects of different new dialysis on-line monitoring devices on hemodynamic stability during intermittent hemodialysis in critically ill patients with acute kidney…
- Trial name
- HEMOTOL (NCT00811109)
- Testing
- Standard Hemodialysis, with Blood Volume Management (BVM®) only, with Blood Volume (BVM®) and Temperature (BTM®) on-line monitoring
- Where
- France
- Volunteers
- 600 people
- Sponsor
- University Hospital, Caen
Multiple Myeloma de Novo Treatment
Multiple Myeloma Treated With Thalidomide Before Autotransplant or With Conventional Chemotherapy and as Consolidation/Maintenance Treatment in Young and Elderly Patients : 3 Randomized Studies.
The aim of the study was to evaluate efficacy and tolerability of Thalidomide in first-line treatment of multiple myeloma as induction treatment in young patients, with Dexamethasone before autotransplant, and in elderly patients…
- Trial name
- MAG 2002 (NCT01070862)
- Testing
- Thalidomide, Dexamethasone, Vincristin , Adriamycin, Dexamethasone = VAD, Thalidomide, melphalan, endoxan, dexamethasone (MCDex-Thal)
- Where
- 3 sites in France
- Sponsor
- University Hospital, Caen
Malignant Mesothelioma, Metastatic Cancer
Mesothelin and Osteopontin as Diagnostic Markers in Patients With Mesothelioma or Atypical Mesothelial Hyperplasia
RATIONALE: Studying levels of mesothelin and osteopontin in samples of blood from patients with mesothelioma or atypical mesothelial hyperplasia may help doctors identify biomarkers related to cancer.
- Trial name
- NCT00899613
- Testing
- laboratory biomarker analysis, study of high risk factors
- Where
- France
- Volunteers
- 270 people
- Sponsor
- University Hospital, Caen
Healthy
Effects of Sleep Deprivation on Food Intake and Motor Activity in Man
Evidence that shortened period of sleep could be a risk factor for weight gain and obesity has grown over the past decade. Concurrent with the obesity epidemic, numerous studies have reported a parallel epidemic of chronic sleep…
- Trial name
- NCT00986492
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Kidney Failure, Acute, Critical Illness
Angiotensin-Converting Enzyme Polymorphism and Acute Renal Failure (ECAREA)
Associations between angiotensin-converting enzyme gene polymorphism and occurrence and outcome of ARDS, and with respiratory complications post cardiopulmonary bypass have already been demonstrated.
- Trial name
- NCT00316576
- Testing
- Blood sampling for PCR
- Where
- France
- Volunteers
- 160 people
- Sponsor
- University Hospital, Caen